NO175429C - Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater - Google Patents

Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater

Info

Publication number: NO175429C
Authority: NO; Norway
Prior art keywords: dehydro; vitamin; derivatives; therapeutically active; analogous process
Prior art date: 1988-01-20

Application number

NO890239A

Other languages

English (en)

Other versions

NO175429B (no

NO890239L (no

NO890239D0 (no

Inventor

Enrico Giuseppe Baggiolini

Bernard Michael Hennessy

Shian-Jan Shiuey

Gary Arthur Truitt

Milan Radoje Uskokovic

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-20

Filing date

1989-01-19

Publication date

1994-10-12

1989-01-19 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1989-01-19 Publication of NO890239D0 publication Critical patent/NO890239D0/no

1989-07-21 Publication of NO890239L publication Critical patent/NO890239L/no

1994-07-04 Publication of NO175429B publication Critical patent/NO175429B/no

1994-10-12 Publication of NO175429C publication Critical patent/NO175429C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO890239A 1988-01-20 1989-01-19 Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater NO175429C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US14593288A	1988-01-20	1988-01-20

Publications (4)

Publication Number	Publication Date
NO890239D0 NO890239D0 (no)	1989-01-19
NO890239L NO890239L (no)	1989-07-21
NO175429B NO175429B (no)	1994-07-04
NO175429C true NO175429C (no)	1994-10-12

Family

ID=22515181

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO890239A NO175429C (no)	1988-01-20	1989-01-19	Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater

Country Status (23)

Country	Link
EP (1)	EP0325279B1 (no)
JP (1)	JPH0764806B2 (no)
KR (1)	KR960009119B1 (no)
AR (1)	AR247551A1 (no)
AT (1)	ATE74350T1 (no)
AU (1)	AU622139B2 (no)
BG (1)	BG60530B2 (no)
CA (1)	CA1337529C (no)
DE (1)	DE58901056D1 (no)
DK (1)	DK169945B1 (no)
ES (1)	ES2033467T3 (no)
FI (1)	FI90764C (no)
GR (1)	GR3004786T3 (no)
HU (1)	HU201007B (no)
IE (1)	IE60921B1 (no)
IL (1)	IL88989A (no)
MC (1)	MC1998A1 (no)
NO (1)	NO175429C (no)
NZ (1)	NZ227641A (no)
PH (1)	PH25605A (no)
PT (1)	PT89486B (no)
YU (1)	YU47298B (no)
ZA (1)	ZA8923B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4804502A (en) *	1988-01-20	1989-02-14	Hoffmann-La Roche Inc.	Vitamin D compounds
EP0398217B1 (de) *	1989-05-18	1994-01-12	F. Hoffmann-La Roche Ag	Dehydrocholecalciferolderivate
AU650751B2 (en) *	1991-05-28	1994-06-30	Wisconsin Alumni Research Foundation	Novel synthesis of 19-nor vitamin D compounds
EP0580968B1 (en) *	1992-05-20	1996-08-28	F. Hoffmann-La Roche Ag	Vitamin D3 fluorinated analogs
US5753638A (en) *	1992-10-07	1998-05-19	Hoffmann-La Roche Inc.	Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
CA2096105A1 (en) *	1992-10-07	1994-04-08	Enrico Giuseppe Baggiolini (Deceased)	Vitamin d3 fluorinated analogs
TW267161B (no) *	1992-11-20	1996-01-01	Hoffmann La Roche
US5401733A (en) *	1993-10-01	1995-03-28	Hoffmann-La Roche Inc.	Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) *	1993-11-24	1995-06-27	Hoffmann-La Roche Inc.	Vitamin D3 fluorinated analogs
TW403735B (en) *	1995-11-22	2000-09-01	Hoffmann La Roche	25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) *	1996-03-21	1999-08-12	F. Hoffmann-La Roche Ag	1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
US5939408A (en) *	1996-05-23	1999-08-17	Hoffman-La Roche Inc.	Vitamin D3 analogs
SG70009A1 (en) *	1996-05-23	2000-01-25	Hoffmann La Roche	Vitamin d3 analogs
DE69813380T2 (de) *	1997-05-02	2003-12-04	Duphar International Research B.V., Weesp	Verfahren zur Herstellung von 16-Dehydro Vitamin D Verbindungen
US6331642B1 (en) *	1999-07-12	2001-12-18	Hoffmann-La Roche Inc.	Vitamin D3 analogs
JP4795023B2 (ja) *	2004-02-03	2011-10-19	中外製薬株式会社	ビタミンｄ化合物及びそれらの合成中間体の合成方法
US8906888B2 (en) *	2005-04-25	2014-12-09	Cytochroma Inc.	Low-calcemic 16,23-diene 25-oxime analogs of 1α,25-dihydroxy vitamin D3
WO2007022433A2 (en) *	2005-08-18	2007-02-22	Bioxell S.P.A.	SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1574685A (en) *	1977-03-24	1980-09-10	Wisconsin Alumni Res Found	Vitamin d3 derivatives
GB2021115B (en) *	1978-05-19	1982-10-06	Wisconsin Alumni Res Found	Vitamin d derivatives
US4360471A (en) *	1981-12-11	1982-11-23	Wisconsin Alumni Research Foundation	23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) *	1983-03-21	1985-04-02	Hoffmann-La Roche Inc.	Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) *	1984-01-30	1985-03-19	Wisconsin Alumni Research Foundation	Hydroxyvitamin D2 isomers
US4612308A (en) *	1984-11-29	1986-09-16	Hoffmann-La Roche Inc.	25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) *	1987-09-14	1990-02-06	Hoffman-La Roche Inc.	Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) *	1988-01-20	1989-02-14	Hoffmann-La Roche Inc.	Vitamin D compounds
EP0398217B1 (de) *	1989-05-18	1994-01-12	F. Hoffmann-La Roche Ag	Dehydrocholecalciferolderivate

1989
- 1989-01-03 ZA ZA8923A patent/ZA8923B/xx unknown
- 1989-01-17 PH PH38057A patent/PH25605A/en unknown
- 1989-01-17 DK DK019789A patent/DK169945B1/da not_active IP Right Cessation
- 1989-01-17 CA CA000588384A patent/CA1337529C/en not_active Expired - Fee Related
- 1989-01-17 NZ NZ227641A patent/NZ227641A/en unknown
- 1989-01-18 HU HU89175A patent/HU201007B/hu not_active IP Right Cessation
- 1989-01-18 IL IL88989A patent/IL88989A/xx not_active IP Right Cessation
- 1989-01-18 AR AR89313011A patent/AR247551A1/es active
- 1989-01-19 IE IE15789A patent/IE60921B1/en not_active IP Right Cessation
- 1989-01-19 KR KR89000514A patent/KR960009119B1/ko not_active IP Right Cessation
- 1989-01-19 AU AU28644/89A patent/AU622139B2/en not_active Ceased
- 1989-01-19 MC MC902029A patent/MC1998A1/xx unknown
- 1989-01-19 JP JP1008782A patent/JPH0764806B2/ja not_active Expired - Fee Related
- 1989-01-19 YU YU11789A patent/YU47298B/sh unknown
- 1989-01-19 NO NO890239A patent/NO175429C/no unknown
- 1989-01-19 PT PT89486A patent/PT89486B/pt not_active IP Right Cessation
- 1989-01-19 FI FI890283A patent/FI90764C/fi not_active IP Right Cessation
- 1989-01-20 EP EP89100974A patent/EP0325279B1/de not_active Expired - Lifetime
- 1989-01-20 ES ES198989100974T patent/ES2033467T3/es not_active Expired - Lifetime
- 1989-01-20 AT AT89100974T patent/ATE74350T1/de not_active IP Right Cessation
- 1989-01-20 DE DE8989100974T patent/DE58901056D1/de not_active Expired - Fee Related
1992
- 1992-06-03 GR GR920401138T patent/GR3004786T3/el unknown
1994
- 1994-02-24 BG BG098544A patent/BG60530B2/bg unknown

Also Published As

Publication number	Publication date
NO175429B (no)	1994-07-04
HUT49317A (en)	1989-09-28
PH25605A (en)	1991-08-08
FI90764B (fi)	1993-12-15
PT89486B (pt)	1993-12-31
IL88989A (en)	1993-08-18
IL88989A0 (en)	1989-08-15
NZ227641A (en)	1991-06-25
IE890157L (en)	1989-07-20
YU47298B (sh)	1995-01-31
HU201007B (en)	1990-09-28
MC1998A1 (fr)	1990-01-26
KR960009119B1 (en)	1996-07-13
DK19789D0 (da)	1989-01-17
DK19789A (da)	1989-07-21
DE58901056D1 (de)	1992-05-07
FI890283A (fi)	1989-07-21
AU2864489A (en)	1989-07-20
FI90764C (fi)	1994-03-25
JPH029861A (ja)	1990-01-12
IE60921B1 (en)	1994-09-07
ES2033467T3 (es)	1993-03-16
CA1337529C (en)	1995-11-07
DK169945B1 (da)	1995-04-10
NO890239L (no)	1989-07-21
ZA8923B (en)	1989-09-27
EP0325279B1 (de)	1992-04-01
KR890011838A (ko)	1989-08-22
BG60530B2 (bg)	1995-07-28
FI890283A0 (fi)	1989-01-19
NO890239D0 (no)	1989-01-19
ATE74350T1 (de)	1992-04-15
AR247551A1 (es)	1995-01-31
EP0325279A1 (de)	1989-07-26
YU11789A (en)	1991-04-30
AU622139B2 (en)	1992-04-02
PT89486A (pt)	1989-10-04
JPH0764806B2 (ja)	1995-07-12
GR3004786T3 (no)	1993-04-28

Similar Documents

Publication	Publication Date	Title
NO174547C (no)	1994-05-25	Analogifremgangsmåte ved fremstilling av terapeutisk aktive didehydro-vitamin-D3-derivater
NO176759C (no)	1995-05-24	Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-substituerte-2-oksindol-derivater
NO174385C (no)	1994-04-27	Analogifremgangsmåte ved fremstilling av terapeutisk aktive spiro-substituerte glutamid-derivater
NO174101C (no)	1994-03-16	Analogifremgangsmåte ved fremstilling av terapeutisk aktive triazolderivater
FI96861C (fi)	1996-09-10	Menetelmä terapeuttisesti aktiivisten substituoitujen indolyylipyrrolijohdannaisten valmistamiseksi
NO179584C (no)	1996-11-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-acylaminotiazoler
NO176758C (no)	1995-05-24	Analogifremgangsmåte for fremstilling av terapeutiske anvendbare tetrazolyl-bifenylylmetyl-pyrimidiner
NO175978C (no)	1995-01-11	Analogifremgangsmåte for fremstilling av terapeutisk aktive bis-aza-bicykliske forbindelser
NO178619C (no)	1996-05-02	Analogifremgangsmåte for fremstilling av terapeutisk aktive di-t-butylfenoler
NO178498C (no)	1996-04-10	Analogifremgangsmåte ved fremstilling av terapeutisk aktive karbapenemderivater
NO173652C (no)	1994-01-12	Analogifremgangsmaate ved fremstilling av et terapeutisk aktivt indazol-3-karboksylsyrederivat
NO174467C (no)	1994-05-11	Analogifremgangsmåte for fremstilling av terapeutisk aktive kromanderivater
NO175429C (no)	1994-10-12	Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater
NO180084C (no)	1997-02-12	Analogifremgangsmåte ved fremstilling av terapeutisk aktive 1,4-dihydropyridinderivater
NO176275C (no)	1995-03-08	Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazinonderivater
NO174959C (no)	1994-08-10	Analogifremgangsmåte for fremstilling av terapeutisk aktive N-aminobutyl-N-fenyl-arylamidderivater
NO173334C (no)	1993-12-01	Analogifremgangsm}te for fremstilling av terapeutisk aktive alkylaminoalkylenderivater 2H-1-benzopyraner
NO178967C (no)	1996-07-10	Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazin-derivater
NO176142C (no)	1995-02-08	Analogifremgangsmåte for fremstilling av terapeutisk aktive aminoalkoksyfenylderivater
NO173784C (no)	1994-02-02	Anaslogifremgangsmaate for fremstilling av terapeutisk aktive tieno-tri-azolo-diazepinderivater
NO176477C (no)	1995-04-12	Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-alkoksymetylsubstituerte kromanderivater
NO174391C (no)	1994-04-27	Analogifremgangsmåte for fremstilling av terapeutisk aktive kromanderivater
NO176100C (no)	1995-02-01	Analogifremgangsmåte for fremstilling av terapeutisk aktive oksodihydropyridyl- og oksodihydropyridazinylkromanderivater
NO175781C (no)	1994-12-07	Analogifremgangsmåte for fremstilling av terapeutisk aktive tetracykliske forbindelser
NO174200C (no)	1994-04-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-imino-6-polyfluoralkoksybenzotiazol-forbindelser