NO149139B - DIMETHYLOX OXPHOSPHONATES FOR USE AS BASIC MATERIAL IN THE PREPARATION OF PHYSIOLOGICALLY ACTIVE PROSTAGLANDINES - Google Patents
DIMETHYLOX OXPHOSPHONATES FOR USE AS BASIC MATERIAL IN THE PREPARATION OF PHYSIOLOGICALLY ACTIVE PROSTAGLANDINES Download PDFInfo
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- NO149139B NO149139B NO750535A NO750535A NO149139B NO 149139 B NO149139 B NO 149139B NO 750535 A NO750535 A NO 750535A NO 750535 A NO750535 A NO 750535A NO 149139 B NO149139 B NO 149139B
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- 238000009987 spinning Methods 0.000 claims description 80
- 239000002131 composite material Substances 0.000 claims description 15
- 125000006850 spacer group Chemical group 0.000 claims description 2
- 241000446313 Lamella Species 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 9
- 239000000203 mixture Substances 0.000 description 6
- 238000010276 construction Methods 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
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- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
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- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
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Description
Spinnedyse. Spinning nozzle.
Denne oppfinnelse angår spinnedyser, nærmere bestemt spinnedyser for frem-bringelse av sammensatte filamenter. This invention relates to spinning nozzles, more specifically spinning nozzles for producing composite filaments.
Fabrikasjonen av kjente spinnedyser for fremstilling av sammensatte filamenter medfører store omkostninger og van-skeligheter. Hullene i spinnedysens munn-stykke må være nøyaktig utformet. Det er vel kjent at dannelsen av disse hull er en kostbar og omstendelig prosess. Resten av spinnedysen må også være meget nøyaktig i utformning og dimensjoner. Dessuten kan ikke store investeringer av tid og penger i en sammensatt spinnedyse på noen måte garantere at det ønskede resultat oppnåes. De kjente sammensatte spinnedyser er dessuten begrenset til spinning av to polymerisater og kan ikke benyttes for spinning av et sammensatt filament av flere enn to polymerisater. Styring av spinneoppløs-ningene gjennom konvensjonelle sammensatte spinnedyser er også meget vanskelig. The manufacture of known spinning nozzles for the production of composite filaments entails great costs and difficulties. The holes in the nozzle of the spinning nozzle must be precisely designed. It is well known that the formation of these holes is an expensive and cumbersome process. The rest of the spinning nozzle must also be very precise in design and dimensions. Furthermore, large investments of time and money in a complex spinning nozzle cannot in any way guarantee that the desired result is achieved. The known composite spinning nozzles are also limited to spinning two polymers and cannot be used for spinning a composite filament of more than two polymers. Controlling the spinning solutions through conventional compound spinning nozzles is also very difficult.
Formålet for og virkningen av foreliggende oppfinnelse er å tilveiebringe en spinnedyse av den type som er beskrevet i innledningen til påstanden, hvor de oven-nevnte ulemper er overvunnet foruten at spinnedysen ifølge oppfinnelsen er av en enkel konstruksjon, kan fremstilles ved lave omkostninger, er lett å montere og demon-tere for rengjøring og utskifting av deler, kan spinne sammensatte filamenter som kan bestå ikke bare av to, men av tre eller flere spinneoppløsninger, idet kvantiteten av hver spinnekomposisjon kan styres meget nøyaktig og kan kombineres umiddel-bart før den trer ut av munnstykkene. The purpose and effect of the present invention is to provide a spinning nozzle of the type described in the introduction to the claim, where the above-mentioned disadvantages are overcome, besides the fact that the spinning nozzle according to the invention is of a simple construction, can be produced at low cost, is easy to assemble and disassemble for cleaning and replacement of parts, can spin composite filaments that can consist not only of two, but of three or more spinning solutions, the quantity of each spinning composition can be controlled very accurately and can be combined immediately before spinning out of the nozzles.
En utførelsesform av foreliggende oppfinnelse angår således en spinnedyse sammensatt av laminerte plater og utmerker seg ved at spinnehodet omfatter et antall stablede laminerte plater, hver forsynt med et flertall adskilte slisser som strekker seg innover fra en rett kant på platen og er forbundet med kanaler hvor hver av kanalene i to tilstøtende plater kommuniserer med en tilførselskilde for spinneoppløsning, idet slissene i to tilstøtende plater møtes i felles punkter ved platenes kanter, hvilke felles punkter danner spinneåpningene og holdes adskilt fra de følgende sett felles punkter ved hjelp av avstandsplater uten slisser. An embodiment of the present invention thus relates to a spinning nozzle composed of laminated plates and is distinguished by the fact that the spinning head comprises a number of stacked laminated plates, each provided with a plurality of separate slots which extend inwards from a straight edge of the plate and are connected by channels where each of the channels in two adjacent plates communicate with a supply source for spinning solution, as the slots in two adjacent plates meet at common points at the edges of the plates, which common points form the spinning openings and are kept separate from the following set of common points by means of spacer plates without slots.
Andre formål og fordeler ved oppfinnelsen vil gå frem av følgende detaljerte beskrivelse under henvisning til tegningen, hvor Other objects and advantages of the invention will become apparent from the following detailed description with reference to the drawing, where
fig. 1 er et perspektiv av en spinnedyse delvis i demontert stand og viser oppfin-nelsens prinsipp og den stablede anordning av de med slisser forsynte lameller som holdes mellom platene og fig. 1 is a perspective view of a spinning nozzle partially disassembled and shows the principle of the invention and the stacked arrangement of the slitted lamellas which are held between the plates and
fig. 2 er et adskilt perspektivisk oppriss som viser den måte hvorpå lamellene kan anordnes for å danne et sammensatt filament som fremkommer ved hjelp av tre forskjellige spinnekomposisjoner. fig. 2 is a detached perspective elevation showing the manner in which the lamellae may be arranged to form a composite filament produced by means of three different spinning compositions.
På tegningen er vist et antall par av tynne plater eller lameller 11 og 12 lagt flatt inn mellom plater 13 (se fig. 1). Hele utstyret klemmes tett sammen ved hjelp av bolter 16 som strekker seg gjennom hull i platene og lamellene. Dette utstyr vil i det følgende bli betegnet som spinnedysen. The drawing shows a number of pairs of thin plates or lamellae 11 and 12 laid flat between plates 13 (see fig. 1). The entire equipment is clamped tightly together by means of bolts 16 which extend through holes in the plates and slats. In the following, this equipment will be referred to as the spinning nozzle.
Hver av de tynne plater eller lameller 11 er forsynt med innbyrdes adskilte parallelle slisser 20 og 21 som strekker seg i en vinkel fra kanten av lamellen og ender i huller 24 henholdsvis 25. Hullene 24 og således også slissene 20 er forbundet ved hjelp av huller 28 i lamellene 12 og boringer 29 i platene 13 med et grenrør 30 i den øverste plate 13. Boringene 29 og hullene ?4 og 28 ligger rett overfor hverandre for å danne en første ledning eller gjennom-strømningskanal for strømning av spinne-oppløsning gjennom de sammensatte lameller og plater. Da hver av slissene 20 er forbundet med disse ledninger eller gjen-nomstrømningskanaler, vil spinneoppløs-ningen strømme ut av spinnedysen gjennom disse slisser. Spinneoppløsningens ba-ner gjennom de første kanaler er antydet med piler 31. Each of the thin plates or lamellas 11 is provided with mutually separated parallel slots 20 and 21 which extend at an angle from the edge of the lamella and end in holes 24 and 25 respectively. The holes 24 and thus also the slots 20 are connected by means of holes 28 in the lamellae 12 and bores 29 in the plates 13 with a manifold 30 in the top plate 13. The bores 29 and the holes ?4 and 28 are directly opposite each other to form a first conduit or through-flow channel for the flow of spinning solution through the assembled slats and plates. As each of the slits 20 is connected by these lines or flow-through channels, the spinning solution will flow out of the spinning nozzle through these slits. The paths of the spin resolution through the first channels are indicated by arrows 31.
Hullene 25 og dermed også slissene 21 er forbundet ved hjelp av huller 35 i lamellene 12 og boringer 36 i platene 13 med et grenrør 38 i den underste plate 13. Hullene 25 og 35 og boringene 36 ligger rett overfor hverandre for å danne en annen ledning eller kanal, gjennom hvilken spinneoppløs-ningen strømmer til og gjennom slissene 21. Banen for den annen spinneoppløsning gjennom det annet sett kanaler er antydet ved pilene 39. The holes 25 and thus also the slots 21 are connected by means of holes 35 in the slats 12 and bores 36 in the plates 13 with a branch pipe 38 in the lower plate 13. The holes 25 and 35 and the bores 36 lie directly opposite each other to form another line or channel, through which the spinning solution flows to and through the slits 21. The path of the second spinning solution through the second set of channels is indicated by the arrows 39.
Hver av de tynne plater eller lameller 12 er forsynt med innbyrdes adskilte parallelle slisser 40 som strekker seg fra kanten av platene til hullene 35 slik at spinne-oppløsning fra grenrøret 38 i den underste plate 13 vil flyte ut av spinnedysen gjennom slissene 40. Each of the thin plates or lamellae 12 is provided with mutually separated parallel slits 40 which extend from the edge of the plates to the holes 35 so that spinning solution from the branch tube 38 in the lower plate 13 will flow out of the spinning nozzle through the slits 40.
Endene av slissene 40 overlappes av endene av slissene 20 i de tynne plater 11, idet endene av slissene 20 og 40 avsluttes ved felles punkter eller på bestemte steder på spinnedysens overflate, slik at en første spinneoppløsning går gjennom slissene 40 og danner et sammensatt filament (ikke vist). Således møtes slissene 20 og 40 ved overflaten av spinnedysen og avgrenser dermed sammensatte spinneåpninger eller munnstykker. The ends of the slits 40 are overlapped by the ends of the slits 20 in the thin plates 11, the ends of the slits 20 and 40 ending at common points or at certain places on the surface of the spinning nozzle, so that a first spinning solution passes through the slits 40 and forms a composite filament ( not shown). Thus, the slits 20 and 40 meet at the surface of the spinning nozzle and thus delimit composite spinning openings or nozzles.
Hver av de tynne plater eller lameller 12 er forsynt med innbyrdes adskilte parallelle slisser 41 som strekker seg fra kanten av platen 12 til huller 28, idet slissene 40 og 41 i lamellen eller platen 12 er parallelle. Således flyter spinneopløsning fra grenrø-ret 30 i den øverste plate 13 til og gjennom slissene 41. Endene av slissene 41 overlappes av endene av slissene 21 i lamellene 11 og danner sammensatte spinnemunnstyk-ker eller åpninger. Slissene 21 og 41 avsluttes med andre ord ved felles punkter eller på bestemte steder på spinnedysens overflate. Således vil den første spinneoppløs-ning som går gjennom slissene 41 forbinde seg med den annen spinneoppløsning som går gjennom slissene 21 og danner sammensatte filamenter, idet de to strømmer av spinneoppløsning møtes ved spinnedysens overflate. Each of the thin plates or slats 12 is provided with mutually separated parallel slits 41 which extend from the edge of the plate 12 to holes 28, the slits 40 and 41 in the lamella or plate 12 being parallel. Thus, spinning solution flows from the branch tube 30 in the top plate 13 to and through the slits 41. The ends of the slits 41 are overlapped by the ends of the slits 21 in the slats 11 and form composite spinning nozzles or openings. In other words, the slits 21 and 41 end at common points or at certain places on the surface of the spinneret. Thus, the first spinning solution that passes through the slits 41 will connect with the second spinning solution that passes through the slits 21 and form composite filaments, the two streams of spinning solution meeting at the surface of the spinning die.
Den første spinneoppløsning trekkes ut av en kilde 48 ved hjelp av en pumpe 49 og presses inn i grenrøret 30 i den øverste plate 13 med en på forhånd fastlagt hastighet og trykk. Den første spinneoppløsning eller komposisjon strømmer deretter gjennom den første kanal (se pilen 31) til og gjennom slisser 20 i lamellene 11 og slissene 41 i lamellene 12. The first spinning solution is extracted from a source 48 by means of a pump 49 and pressed into the branch pipe 30 in the upper plate 13 at a predetermined speed and pressure. The first spinning solution or composition then flows through the first channel (see arrow 31) to and through slits 20 in the lamellae 11 and slits 41 in the lamellae 12.
Den annen spinneoppløsning trekkes ut fra en kilde 52 ved hjelp av en pumpe 53 og presses inn i grenrøret 38 i den ned-erste plate 13 under et på forhånd fastlagt trykk og hastighet. Den annen spinneopp-løsning eller komposisjon flyter deretter gjennom den annen kanal (se pilene 39) til og gjennom slissene 21 i lamellene 11 og slissene 40 i lamellene 12. The second spinning solution is extracted from a source 52 by means of a pump 53 and is pressed into the branch pipe 38 in the lower plate 13 under a predetermined pressure and speed. The second spinning solution or composition then flows through the second channel (see arrows 39) to and through the slits 21 in the lamellae 11 and the slits 40 in the lamellae 12.
Den første spinneoppløsning flyter gjennom slissene 20 og 41 og kombineres med den annen spinneoppløsning som strømmer gjennom slissene 40 og 21 på den ovenfor beskrevne måte og danner sammensatte filamenter. Da strømmen av hver spinneoppløsning kan styres nøyaktig ved innstilling av pumpehastighetene og da de to oppløsninger ikke møtes før de når spinnedysens overflate, kan den mengde av hver oppløsning som går til spinning av filamentene styres meget nøyaktig. Det faktum at de to oppløsninger møtes ved spinnedysens åpninger sikrer en meget skarp grenselinje mellom de forskjellige komposisjoner i det spundne filament. The first spinning solution flows through the slits 20 and 41 and is combined with the second spinning solution which flows through the slits 40 and 21 in the manner described above and forms composite filaments. As the flow of each spinning solution can be precisely controlled by setting the pump speeds and as the two solutions do not meet before they reach the surface of the spinning nozzle, the amount of each solution that goes to spinning the filaments can be controlled very precisely. The fact that the two solutions meet at the openings of the spinning nozzle ensures a very sharp boundary between the different compositions in the spun filament.
Da tverrsnittsarealet av hvert spinne-munnstykke er det kombinerte tverrsnitts-areal av slissene 20 og 40 (21 og 41), må nødvendigvis lamellene 11 og 12 være meget tynne. Disse slisser kan være stanset ut av plater i en masseproduksjonsoperasjon. Således blir omkostningene og tiden som går med til fremstillingen av denne spinnedyse meget små. Det vil fremgå at mens slissene 20 og 40 (21 og 41) strekker seg bort fra kantene av lamellene 11 henholdsvis 12 i forskjellige retninger, har de to lameller identisk utformning, dvs. at lamellen 12 er fremstilt identisk med lamellen 11 og deretter vendt og satt sammen med lamellen 11. Since the cross-sectional area of each spinning nozzle is the combined cross-sectional area of the slits 20 and 40 (21 and 41), the lamellae 11 and 12 must necessarily be very thin. These slots may be punched out of sheets in a mass production operation. Thus, the costs and time involved in the production of this spinning nozzle are very small. It will be seen that while the slits 20 and 40 (21 and 41) extend away from the edges of the lamellas 11 and 12 respectively in different directions, the two lamellas have an identical design, i.e. that the lamella 12 is produced identically to the lamella 11 and then turned and assembled with the lamella 11.
Fig. 2 viser en spinnedyse som benyttes til fremstilling av sammensatte filamenter bestående av tre spinneoppløsninger. Tre lameller 60, 61 og 62, som er forsynt med slisser henholdsvis 66, 67 og 68, er således klemt sammen at endene av slissene 66—68 møtes og overlapper hverandre ved et felles punkt eller forut bestemt sted spinnedysens overflate og danner et spinnemunn-stykke eller en åpning. Slissene 66—68 di-vergerer fra disse krysningspunkter ved spinnedysens overflate mot huller 71 henholdsvis 72, henholdsvis 73. Fig. 2 shows a spinning nozzle which is used for the production of composite filaments consisting of three spinning solutions. Three lamellae 60, 61 and 62, which are provided with slits 66, 67 and 68 respectively, are clamped together in such a way that the ends of the slits 66-68 meet and overlap each other at a common point or predetermined place on the surface of the spinning die and form a spinning mouth piece or an opening. The slits 66-68 diverge from these crossing points at the surface of the spinning nozzle towards holes 71, respectively 72, and 73, respectively.
Tre spinneoppløsninger mates til hullene 71—73 fra grenrør, såsom 30 og 38 (fig. 1). Disse tre oppløsninger eller komposisjoner strømmer gjennom sine respek-tive slisser 66—68 og møtes ved spinnedy- | sens overflate, hvorved der dannes et sammensatt filament som består av tre opp-løsninger. Three spinning solutions are fed to holes 71-73 from branch pipes, such as 30 and 38 (fig. 1). These three solutions or compositions flow through their respective slots 66-68 and meet at the spinnedy | sen's surface, whereby a composite filament is formed which consists of three solutions.
Det er innlysende at endog fler enn tre lameller kan legges plant sammen for å danne en spinnedyse som er istand til å fremstille et sammensatt filament bestående av fire eller flere forskjellige spinne-oppløsninger. Antallet lameller som kan benyttes er bare begrenset ved størrelsen og den innbyrdes avstand av slissene og hullene som slissene fører til. It is obvious that even more than three lamellae can be laid flat together to form a spinning die which is capable of producing a composite filament consisting of four or more different spinning solutions. The number of slats that can be used is only limited by the size and the mutual distance of the slots and the holes that the slots lead to.
Det vil uten videre fremgå at spinnedysen ifølge foreliggende oppfinnelse har en enkel konstruksjon og er lett å fremstille. De vanligvis vanskelige problemer og operasjoner man støter på ved fremstilling av konvensjonelle spinnedyser er elimert. Det er heller ikke nødvendig å kassere denne spinnedyse hvis en av spinneåpningene blir defekt på grunn av slitasje eller lig-nende som tilfellet er ved en vanlig spinnedyse. Isteden kan den lamell som omfatter den defekte åpning bare skiftes ut. Enskjønt konvensjonelle spinnedyser er meget kostbare, må hele spinnedysen kas-seres når slitasje (bevirket ved oppløsnin-gens strømning gjennom hullet) gjør bare et eller to av spinnehullene overdimensjo-nert. Denne kostbare praksis er fullstendig eliminert ved foreliggende oppfinnelse. It will be readily apparent that the spinning nozzle according to the present invention has a simple construction and is easy to manufacture. The usually difficult problems and operations encountered in the manufacture of conventional spinning nozzles are eliminated. It is also not necessary to discard this spinning nozzle if one of the spinning openings becomes defective due to wear or the like, as is the case with a normal spinning nozzle. Instead, the lamella that includes the defective opening can simply be replaced. Although conventional spinning nozzles are very expensive, the entire spinning nozzle must be discarded when wear (caused by the flow of the solution through the hole) makes only one or two of the spinning holes oversized. This costly practice is completely eliminated by the present invention.
En annen ulempe ved konvensjonelle spinnedyser består i at skader på et hull under fremstillingsprosessen kan være øde-leggende for hele spinnedysen. Således kan ved en vanlig spinnedyse som har 20.000 hull en skade på det siste hull under fremstillingen av spinnedysen bety at omkostningene ved utformningen av de første 19.999 hull er et tap. Dette problem er fullstendig overvunnet ved foreliggende oppfinnelse idet de lameller som danner spin-nedysene eller spinneåpningene kan un-dersøkes før sammensetningen for å sikre at bare godtagbare lameller benyttes. Another disadvantage of conventional spinning nozzles is that damage to a hole during the manufacturing process can be devastating for the entire spinning nozzle. Thus, in the case of a normal spinning die that has 20,000 holes, damage to the last hole during the manufacture of the spinning die can mean that the costs of designing the first 19,999 holes are a loss. This problem is completely overcome by the present invention in that the lamellae which form the spin-down nozzles or the spinning openings can be examined before assembly to ensure that only acceptable lamellae are used.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30481372A | 1972-11-08 | 1972-11-08 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO750535L NO750535L (en) | 1974-05-09 |
| NO149139B true NO149139B (en) | 1983-11-14 |
| NO149139C NO149139C (en) | 1984-02-29 |
Family
ID=23178133
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO4288/73A NO147836C (en) | 1972-11-08 | 1973-11-07 | NEW 16-ARYLOXY SUBSTITUTED OMEGA-TETRANORPROSTA GLANDINES FOR USE AS FERTILITY CONTROLLING AGENT, ANTI-PREGNANCY OR BRUNIC CYCLE SYNCHRONIZING AGENT |
| NO743493A NO148998C (en) | 1972-11-08 | 1974-09-26 | OUTSTANDING MATERIALS USED FOR THE PREPARATION OF SUBSTITUTED OMEGA-PENTANORPROSTAGLANDINES |
| NO750535A NO149139C (en) | 1972-11-08 | 1975-02-18 | DIMETHYLOX OXPHOSPHONATES FOR USE AS BASIC MATERIAL IN THE PREPARATION OF PHYSIOLOGICALLY ACTIVE PROSTAGLANDINES |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO4288/73A NO147836C (en) | 1972-11-08 | 1973-11-07 | NEW 16-ARYLOXY SUBSTITUTED OMEGA-TETRANORPROSTA GLANDINES FOR USE AS FERTILITY CONTROLLING AGENT, ANTI-PREGNANCY OR BRUNIC CYCLE SYNCHRONIZING AGENT |
| NO743493A NO148998C (en) | 1972-11-08 | 1974-09-26 | OUTSTANDING MATERIALS USED FOR THE PREPARATION OF SUBSTITUTED OMEGA-PENTANORPROSTAGLANDINES |
Country Status (29)
| Country | Link |
|---|---|
| JP (3) | JPS5416491B2 (en) |
| AR (3) | AR200585A1 (en) |
| AT (3) | AT367034B (en) |
| AU (1) | AU470375B2 (en) |
| BE (1) | BE806995A (en) |
| CA (3) | CA1085831A (en) |
| CH (1) | CH597176A5 (en) |
| CS (3) | CS182791B2 (en) |
| DD (4) | DD118856A5 (en) |
| DE (1) | DE2355540C2 (en) |
| DK (1) | DK144247C (en) |
| ES (3) | ES420325A1 (en) |
| FI (1) | FI60389C (en) |
| FR (3) | FR2205335B1 (en) |
| GB (3) | GB1456514A (en) |
| HK (3) | HK27979A (en) |
| HU (3) | HU172703B (en) |
| IE (1) | IE39537B1 (en) |
| IL (1) | IL43589A (en) |
| IN (1) | IN139384B (en) |
| KE (3) | KE2930A (en) |
| MY (3) | MY7900246A (en) |
| NL (1) | NL164273C (en) |
| NO (3) | NO147836C (en) |
| PH (3) | PH13272A (en) |
| SE (4) | SE448992B (en) |
| SU (4) | SU584766A3 (en) |
| YU (3) | YU39715B (en) |
| ZA (1) | ZA738554B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929862A (en) * | 1974-01-08 | 1975-12-30 | Upjohn Co | Substituted tolylesters of PGF{HD 2{B {60 |
| US3986764A (en) * | 1975-03-31 | 1976-10-19 | Gte Automatic Electric Laboratories Incorporated | Panel for supporting a pair of elongated mating connectors and selectively locking them together |
| GB1506816A (en) * | 1975-03-31 | 1978-04-12 | Upjohn Co | Prostaglandins |
| ES449162A1 (en) * | 1975-06-23 | 1977-12-16 | Syntex Inc | 16-Phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives |
| GB1516414A (en) * | 1975-08-22 | 1978-07-05 | Ici Ltd | Prostane derivatives |
| SE7809008L (en) * | 1977-12-12 | 1979-06-13 | Upjohn Co | USE OF PROSTAGLAND TYPE AMIDES TO CONTROL OR REGULATE THE REPRODUCTION CYCLE IN INDIVIDUALS OF MAMMALS |
| IN150279B (en) * | 1978-01-16 | 1982-09-04 | Pfizer | |
| NZ503738A (en) * | 1997-09-09 | 2001-05-25 | Procter & Gamble | Aromatic C16-20-substituted tetrahydro prostaglandin F analogues useful as FP agonists |
| DE60015508T2 (en) | 1999-03-05 | 2005-04-21 | Univ Durham | C-16 UNAUDITED FP-SELECTIVE PROSTAGLANDIN ANALOGUE |
| US6894175B1 (en) | 1999-08-04 | 2005-05-17 | The Procter & Gamble Company | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| US20020037914A1 (en) | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| JP2002329615A (en) * | 2001-05-02 | 2002-11-15 | Ohira Denshi Kk | Toroidal coil |
| US6476064B1 (en) * | 2001-06-13 | 2002-11-05 | Allergan, Inc. | Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents |
| WO2006047466A2 (en) | 2004-10-21 | 2006-05-04 | Duke University | Ophthamological drugs |
| US8722739B2 (en) | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
| US8623918B2 (en) | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1324737A (en) * | 1970-11-02 | 1973-07-25 | Upjohn Co | Prostaglandins and the preparation thereof |
| IE37602B1 (en) * | 1971-05-11 | 1977-08-31 | Ici Ltd | Cyclopentane derivatives |
-
1972
- 1972-11-07 DD DD182498*A patent/DD118856A5/xx unknown
-
1973
- 1973-10-29 SE SE7314686A patent/SE448992B/en unknown
- 1973-11-07 PH PH15191A patent/PH13272A/en unknown
- 1973-11-07 CH CH1563973A patent/CH597176A5/xx not_active IP Right Cessation
- 1973-11-07 IE IE2002/73A patent/IE39537B1/en unknown
- 1973-11-07 AR AR250885A patent/AR200585A1/en active
- 1973-11-07 GB GB2285876A patent/GB1456514A/en not_active Expired
- 1973-11-07 NL NL7315263.A patent/NL164273C/en not_active IP Right Cessation
- 1973-11-07 FI FI3443/73A patent/FI60389C/en active
- 1973-11-07 GB GB2395076A patent/GB1456513A/en not_active Expired
- 1973-11-07 BE BE1005485A patent/BE806995A/en not_active IP Right Cessation
- 1973-11-07 DD DD182497*A patent/DD117233A5/xx unknown
- 1973-11-07 DD DD174504A patent/DD109212A5/xx unknown
- 1973-11-07 ZA ZA738554A patent/ZA738554B/en unknown
- 1973-11-07 DD DD182499*A patent/DD119411A5/xx unknown
- 1973-11-07 IN IN2448/CAL/73A patent/IN139384B/en unknown
- 1973-11-07 ES ES420325A patent/ES420325A1/en not_active Expired
- 1973-11-07 AU AU62247/73A patent/AU470375B2/en not_active Expired
- 1973-11-07 YU YU2880/73A patent/YU39715B/en unknown
- 1973-11-07 AT AT0936973A patent/AT367034B/en not_active IP Right Cessation
- 1973-11-07 FR FR7339544A patent/FR2205335B1/fr not_active Expired
- 1973-11-07 NO NO4288/73A patent/NO147836C/en unknown
- 1973-11-07 IL IL43589A patent/IL43589A/en unknown
- 1973-11-07 DK DK601073A patent/DK144247C/en not_active IP Right Cessation
- 1973-11-07 CA CA185,274A patent/CA1085831A/en not_active Expired
- 1973-11-07 GB GB5175873A patent/GB1456512A/en not_active Expired
- 1973-11-07 JP JP12527273A patent/JPS5416491B2/ja not_active Expired
- 1973-11-07 DE DE2355540A patent/DE2355540C2/en not_active Expired
- 1973-11-08 HU HU72PI00000399A patent/HU172703B/en unknown
- 1973-11-08 CS CS7300007669A patent/CS182791B2/en unknown
- 1973-11-08 HU HU73PI00000452A patent/HU171819B/en unknown
- 1973-11-08 CS CS7500006066A patent/CS182794B2/en unknown
- 1973-11-08 CS CS7500006065A patent/CS182793B2/en unknown
- 1973-11-08 HU HU73PI451A patent/HU173507B/en unknown
- 1973-11-11 SU SU7301971722A patent/SU584766A3/en active
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1974
- 1974-06-06 AR AR254090A patent/AR202931A1/en active
- 1974-06-06 AR AR254091A patent/AR199966A1/en active
- 1974-09-26 NO NO743493A patent/NO148998C/en unknown
- 1974-12-18 ES ES433046A patent/ES433046A1/en not_active Expired
- 1974-12-18 ES ES433047A patent/ES433047A1/en not_active Expired
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1975
- 1975-02-18 NO NO750535A patent/NO149139C/en unknown
- 1975-02-18 SU SU752106791A patent/SU667141A3/en active
- 1975-02-19 SU SU752106125A patent/SU893130A3/en active
- 1975-07-24 PH PH17410A patent/PH13110A/en unknown
- 1975-07-24 PH PH17409A patent/PH13325A/en unknown
- 1975-08-22 FR FR7526059A patent/FR2279729A1/en active Granted
- 1975-08-22 FR FR7526060A patent/FR2283146A1/en active Granted
-
1976
- 1976-07-23 AT AT544576A patent/AT360672B/en not_active IP Right Cessation
- 1976-07-23 AT AT544676A patent/AT353285B/en active
- 1976-10-15 JP JP51123737A patent/JPS5253841A/en active Pending
- 1976-10-15 JP JP51123738A patent/JPS5257147A/en active Pending
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1977
- 1977-01-24 SE SE7700717A patent/SE436278B/en not_active IP Right Cessation
- 1977-01-24 SE SE7700718A patent/SE431756B/en not_active IP Right Cessation
- 1977-01-24 SE SE7700716A patent/SE445111B/en not_active IP Right Cessation
- 1977-07-11 CA CA341,898A patent/CA1088931A/en not_active Expired
- 1977-07-11 CA CA341,897A patent/CA1088930A/en not_active Expired
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1978
- 1978-07-27 SU SU782629453A patent/SU745362A3/en active
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1979
- 1979-03-15 KE KE2930A patent/KE2930A/en unknown
- 1979-03-15 KE KE2932A patent/KE2932A/en unknown
- 1979-03-15 KE KE2931A patent/KE2931A/en unknown
- 1979-05-03 HK HK279/79A patent/HK27979A/en unknown
- 1979-05-03 HK HK281/79A patent/HK28179A/en unknown
- 1979-05-03 HK HK280/79A patent/HK28079A/en unknown
- 1979-12-30 MY MY246/79A patent/MY7900246A/en unknown
- 1979-12-30 MY MY245/79A patent/MY7900245A/en unknown
- 1979-12-30 MY MY243/79A patent/MY7900243A/en unknown
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1980
- 1980-10-23 YU YU2706/80A patent/YU37316B/en unknown
- 1980-10-23 YU YU2707/80A patent/YU36975B/en unknown
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