NL301276I2 - omaveloxolon of een farmaceutisch aanvaardbaar zout daarvan - Google Patents

omaveloxolon of een farmaceutisch aanvaardbaar zout daarvan

Info

Publication number: NL301276I2
Authority: NL; Netherlands
Prior art keywords: omaveloxolone; pharmaceutically acceptable; acceptable salt; salt; pharmaceutically
Prior art date: 2012-04-27

Application number

NL301276C

Other languages

English (en)

Original Assignee

Reata Pharmaceuticals Holdings Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-04-27

Filing date

2024-05-29

Publication date

2024-06-24

2024-05-29 Application filed by Reata Pharmaceuticals Holdings Llc filed Critical Reata Pharmaceuticals Holdings Llc

2024-06-24 Publication of NL301276I2 publication Critical patent/NL301276I2/nl

Links

RJCWBNBKOKFWNY-IDPLTSGASA-N n-[(4as,6ar,6bs,8ar,12as,14ar,14bs)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicen-4a-yl]-2,2-difluoropropanamide Chemical compound C([C@@]12C)=C(C#N)C(=O)C(C)(C)[C@@H]1CC[C@]1(C)C2=CC(=O)[C@@H]2[C@@H]3CC(C)(C)CC[C@]3(NC(=O)C(F)(F)C)CC[C@]21C RJCWBNBKOKFWNY-IDPLTSGASA-N 0.000 title 1
229950008128 omaveloxolone Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/47—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of rings being part of condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Toxicology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

NL301276C 2012-04-27 2024-05-29 omaveloxolon of een farmaceutisch aanvaardbaar zout daarvan NL301276I2 (nl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201261687669P	2012-04-27	2012-04-27
US201361775288P	2013-03-08	2013-03-08
US201361780444P	2013-03-13	2013-03-13
PCT/US2013/038064 WO2013163344A1 (en)	2012-04-27	2013-04-24	2.2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof

Publications (1)

Publication Number	Publication Date
NL301276I2 true NL301276I2 (nl)	2024-06-24

Family

ID=49483867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL301276C NL301276I2 (nl)	2012-04-27	2024-05-29	omaveloxolon of een farmaceutisch aanvaardbaar zout daarvan

Country Status (40)

Country	Link
US (5)	US8993640B2 (nl)
EP (2)	EP3444261B1 (nl)
JP (2)	JP6410710B2 (nl)
KR (1)	KR102101774B1 (nl)
CN (1)	CN104395332B (nl)
AR (1)	AR092823A1 (nl)
AU (1)	AU2013251602B2 (nl)
BR (1)	BR112014026640B1 (nl)
CA (1)	CA2869783C (nl)
CL (1)	CL2014002886A1 (nl)
CO (1)	CO7170182A2 (nl)
CY (3)	CY1119333T1 (nl)
DK (2)	DK2841445T3 (nl)
DO (1)	DOP2014000236A (nl)
EA (1)	EA030468B1 (nl)
ES (2)	ES2861393T3 (nl)
FI (1)	FIC20240012I1 (nl)
FR (1)	FR24C1015I1 (nl)
HK (2)	HK1207086A1 (nl)
HR (1)	HRP20171275T1 (nl)
HU (3)	HUE053113T2 (nl)
IL (1)	IL235275B (nl)
LT (2)	LT2841445T (nl)
ME (1)	ME02926B (nl)
MX (1)	MX357060B (nl)
MY (1)	MY172750A (nl)
NL (1)	NL301276I2 (nl)
NZ (1)	NZ630222A (nl)
PE (1)	PE20150160A1 (nl)
PL (2)	PL2841445T3 (nl)
PT (2)	PT3444261T (nl)
RS (2)	RS56154B1 (nl)
SG (1)	SG11201406868XA (nl)
SI (2)	SI2841445T1 (nl)
SM (2)	SMT201700396T1 (nl)
TW (2)	TW201348245A (nl)
UA (1)	UA116209C2 (nl)
UY (1)	UY34764A (nl)
WO (1)	WO2013163344A1 (nl)
ZA (1)	ZA201407326B (nl)

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KR20150003875A (ko)	2015-01-09
WO2013163344A1 (en)	2013-10-31
RS56154B1 (sr)	2017-11-30
TW201726701A (zh)	2017-08-01
US20180009839A1 (en)	2018-01-11
NZ630222A (en)	2016-06-24
SG11201406868XA (en)	2014-11-27
CY2024012I1 (el)	2024-12-13
AU2013251602B2 (en)	2017-09-28
FR24C1015I1 (fr)	2024-06-28
HRP20171275T1 (hr)	2017-10-20
BR112014026640B1 (pt)	2021-05-18
JP6410710B2 (ja)	2018-10-24
UY34764A (es)	2013-11-29
JP6637136B2 (ja)	2020-01-29
HUE035673T2 (en)	2018-05-28
SMT201700396T1 (it)	2017-09-07
ME02926B (me)	2018-04-20
US12065464B2 (en)	2024-08-20
US20150259377A1 (en)	2015-09-17
EP3444261A1 (en)	2019-02-20
CL2014002886A1 (es)	2015-02-06
HK1207086A1 (en)	2016-01-22
PE20150160A1 (es)	2015-02-19
ES2634315T3 (es)	2017-09-27
CY1124130T1 (el)	2022-05-27
US9701709B2 (en)	2017-07-11
CA2869783A1 (en)	2013-10-31
EP2841445B1 (en)	2017-06-14
BR112014026640A2 (pt)	2017-07-18
US20130324599A1 (en)	2013-12-05
ZA201407326B (en)	2016-10-26
PT3444261T (pt)	2021-03-12
US20250051388A1 (en)	2025-02-13
SI2841445T1 (sl)	2017-12-29
PT2841445T (pt)	2017-09-01
SMT202100166T1 (it)	2021-05-07
KR102101774B1 (ko)	2020-04-20
HUS2400010I1 (hu)	2024-05-28
LT3444261T (lt)	2021-05-10
ES2861393T3 (es)	2021-10-06
US20210355156A1 (en)	2021-11-18
EA030468B1 (ru)	2018-08-31
IL235275B (en)	2018-03-29
EP3444261B1 (en)	2021-01-13
CO7170182A2 (es)	2015-01-28
MX2014013076A (es)	2015-05-11
DOP2014000236A (es)	2015-04-30
TW201348245A (zh)	2013-12-01
JP2015521166A (ja)	2015-07-27
PL3444261T3 (pl)	2021-07-19
CA2869783C (en)	2022-06-21
CN104395332A (zh)	2015-03-04
MX357060B (es)	2018-06-25
HUE053113T2 (hu)	2021-06-28
DK3444261T3 (da)	2021-03-08
CN104395332B (zh)	2017-01-18
MY172750A (en)	2019-12-11
UA116209C2 (uk)	2018-02-26
EA201491972A1 (ru)	2015-02-27
TWI623548B (zh)	2018-05-11
CY1119333T1 (el)	2018-02-14
DK2841445T3 (en)	2017-09-11
AU2013251602A1 (en)	2014-10-23
JP2019011349A (ja)	2019-01-24
EP2841445A1 (en)	2015-03-04
US11078230B2 (en)	2021-08-03
PL2841445T3 (pl)	2017-10-31
US8993640B2 (en)	2015-03-31
RS61544B1 (sr)	2021-04-29
HK1207085A1 (en)	2016-01-22
SI3444261T1 (sl)	2021-04-30
LT2841445T (lt)	2017-09-11
CY2024012I2 (el)	2024-12-13
AR092823A1 (es)	2015-05-06
FIC20240012I1 (fi)	2024-04-18

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