ATE141646T1
(de)
|
1986-04-09 |
1996-09-15 |
Genzyme Corp |
Genetisch transformierte tiere, die ein gewünschtes protein in milch absondern
|
GB8615942D0
(en)
*
|
1986-06-30 |
1986-08-06 |
Animal & Food Research Council |
Peptide production
|
US5366894A
(en)
*
|
1986-06-30 |
1994-11-22 |
Pharmaceutical Proteins Limited |
Peptide production
|
EP0832981A1
(en)
*
|
1987-02-17 |
1998-04-01 |
Pharming B.V. |
DNA sequences to target proteins to the mammary gland for efficient secretion
|
US4873316A
(en)
*
|
1987-06-23 |
1989-10-10 |
Biogen, Inc. |
Isolation of exogenous recombinant proteins from the milk of transgenic mammals
|
JP2707466B2
(ja)
*
|
1988-07-06 |
1998-01-28 |
第一製薬株式会社 |
遺伝子導入非ヒト動物
|
GB8823869D0
(en)
*
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
US5650503A
(en)
*
|
1988-11-11 |
1997-07-22 |
Ppl Therapeutics (Scotland) Limited |
Genetic construct of which protein coding DNA comprises introns and is designed for protein production in transgenic animals
|
GB8826446D0
(en)
*
|
1988-11-11 |
1988-12-14 |
Agricultural & Food Res |
Peptide production
|
US5464764A
(en)
*
|
1989-08-22 |
1995-11-07 |
University Of Utah Research Foundation |
Positive-negative selection methods and vectors
|
US6689610B1
(en)
|
1989-08-22 |
2004-02-10 |
University Of Utah Research Foundation |
Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
|
US5633076A
(en)
*
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
RU2095414C1
(ru)
*
|
1989-12-01 |
1997-11-10 |
Джен Фарминг Ойроп БВ |
Трансген для получения рекомбинантного полипептида в молоке трансгенных коров, способ получения трансгенной коровы (варианты), молоко от трансгенной коровы, пищевой состав
|
DE69133534T2
(de)
|
1990-03-08 |
2006-12-28 |
Fujitsu Ltd., Kawasaki |
Schichtstruktur mit Kontaktöffnung und Verfahren zur Herstellung derselben
|
JPH04365487A
(ja)
*
|
1990-04-11 |
1992-12-17 |
Consortium Elektrochem Ind Gmbh |
組換dna−構造体、組換ベクター、トランスゲン動物の乳からの蛋白質の取得法、トランスゲン動物の製法及びトランスゲン動物の乳
|
US6262336B1
(en)
|
1991-01-11 |
2001-07-17 |
American Red Cross |
Expression of a heterologous protein C in mammary tissue of transgenic animals using a long whey acidic protein promoter
|
US6984772B1
(en)
|
1994-02-18 |
2006-01-10 |
Virginia Tech Intellectual Properties, Inc. |
Transgenic non-human mammals producing fibrinogen in their milk
|
US5965789A
(en)
*
|
1991-01-11 |
1999-10-12 |
American Red Cross |
Engineering protein posttranslational modification by PACE/furin in transgenic non-human mammals
|
US5831141A
(en)
*
|
1991-01-11 |
1998-11-03 |
United States Of America As Represented By The Department Of Health And Human Services |
Expression of a heterologous polypeptide in mammary tissue of transgenic non-human mammals using a long whey acidic protein promoter
|
JPH06507307A
(ja)
*
|
1991-01-11 |
1994-08-25 |
アメリカン・レツド・クロス |
トランスジェニック動物の乳腺組織における活性ヒトプロテインcの発現
|
US5965788A
(en)
*
|
1992-06-12 |
1999-10-12 |
Institut National De La Recherche Agronomique |
Transgenic non-human mammal comprising a rabbit WAP promoter
|
FR2677652B1
(fr)
*
|
1991-06-12 |
2005-05-27 |
Agronomique Inst Nat Rech |
Procede de preparation d'une proteine d'interet dans le lait d'un animal transgenique, produit obtenu et cellule eucaryote utilisee.
|
US6268545B1
(en)
|
1991-06-12 |
2001-07-31 |
Institut National De La Recherche Agronomique |
Transgenic non-human mammal comprising a rabbit WAP promoter, uses thereof, and a DNA construct comprising the rabbit WAP promoter
|
WO1993004171A1
(en)
*
|
1991-08-19 |
1993-03-04 |
Symbicom Aktiebolag |
Human beta-casein, process for producing it and use thereof
|
GB9119338D0
(en)
|
1991-09-10 |
1991-10-23 |
Inst Of Animal Physiology And |
Control of gene expression
|
US6448469B1
(en)
|
1991-10-02 |
2002-09-10 |
Genzyme Corporation |
Production of membrane proteins in the milk of transgenic nonhuman mammals
|
DK8892D0
(da)
*
|
1992-01-23 |
1992-01-23 |
Symbicom Ab |
Humant proteingen
|
AU4537393A
(en)
*
|
1992-06-15 |
1994-01-04 |
Gene Pharming Europe Bv |
Production of recombinant polypeptides by bovine species and transgenic methods
|
US5667839A
(en)
*
|
1993-01-28 |
1997-09-16 |
Collagen Corporation |
Human recombinant collagen in the milk of transgenic animals
|
US5856178A
(en)
*
|
1993-08-30 |
1999-01-05 |
Utah State University |
DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
|
US20030033617A1
(en)
|
1996-04-10 |
2003-02-13 |
Gyula Hadlaczky |
Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
|
US6077697A
(en)
|
1996-04-10 |
2000-06-20 |
Chromos Molecular Systems, Inc. |
Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
|
AU3672697A
(en)
*
|
1996-07-24 |
1998-02-10 |
University Of Maryland |
The butyrophilin gene promoter and uses thereof
|
US6011197A
(en)
|
1997-03-06 |
2000-01-04 |
Infigen, Inc. |
Method of cloning bovines using reprogrammed non-embryonic bovine cells
|
DK0975755T3
(da)
|
1997-04-16 |
2007-06-11 |
Millennium Pharm Inc |
CRSP-protein (cysteinrige udskilte proteiner), nukleinsyremolekyler der koder herfor samt anvendelser deraf
|
US6087166A
(en)
|
1997-07-03 |
2000-07-11 |
Basf Aktiengesellschaft |
Transcriptional activators with graded transactivation potential
|
OA11520A
(en)
|
1997-10-20 |
2004-02-09 |
Genzyme Transgenics Corp |
Novel modified MSP-1 nucleic acid sequences and methods for increasing mRNA levels and protein expression in cell systems.
|
US6733991B1
(en)
|
1998-05-08 |
2004-05-11 |
Osi Pharmaceuticals, Inc. |
AGS proteins and nucleic acid molecules and uses therefor
|
US6746852B1
(en)
|
1998-05-08 |
2004-06-08 |
Osi Pharmaceuticals, Inc. |
AGS proteins and nucleic acid molecules and uses thereof
|
US20030005468A1
(en)
*
|
1998-06-19 |
2003-01-02 |
Meade Harry M. |
Methods and vectors for improving nucleic acid expression
|
US6258998B1
(en)
|
1998-11-24 |
2001-07-10 |
Infigen, Inc. |
Method of cloning porcine animals
|
WO2000040693A2
(en)
*
|
1999-01-06 |
2000-07-13 |
Atlantic Biopharmaceuticals, Inc. |
Expression of secreted human alpha-fetoprotein in transgenic animals
|
EP2301947A3
(en)
|
1999-02-26 |
2011-11-23 |
Millennium Pharmaceuticals, Inc. |
Secreted proteins and uses thereof
|
US6774120B1
(en)
|
1999-06-01 |
2004-08-10 |
Sarah Ferber |
Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
|
US8778899B2
(en)
|
1999-06-01 |
2014-07-15 |
Sarah Ferber |
Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
|
TR200500004T2
(tr)
|
1999-06-25 |
2005-03-21 |
Basf Aktiengesellschaft |
Karbon metabolizma ve enerji üretimindeki proteinleri dodlayan korynebacterium glutamicum genleri
|
US7291714B1
(en)
|
1999-06-30 |
2007-11-06 |
Millennium Pharmaceuticals, Inc. |
Glycoprotein VI and uses thereof
|
EP1702980A1
(en)
|
1999-07-01 |
2006-09-20 |
Basf Aktiengesellschaft |
Corynebacterium glutamicum gene encoding Hpr of phosphoenolpyruvate:sugar phosphotransferase system
|
NZ517955A
(en)
|
1999-08-23 |
2004-03-26 |
Dana Farber Cancer Inst Inc |
PD-1, a receptor for B7-4 for modulating the immune response
|
EP1254169B1
(en)
|
1999-12-30 |
2007-05-09 |
President And Fellows of Harvard College |
Methods relating to modulation of th2 cell subset activity by modulation of xbp-1 activity
|
KR20020073580A
(ko)
|
2000-02-09 |
2002-09-27 |
바스프 악티엔게젤샤프트 |
신규 연장효소 유전자 및 다가불포화 지방산의 제조 방법
|
WO2001064882A2
(en)
|
2000-02-29 |
2001-09-07 |
Millennium Pharmaceuticals, Inc. |
1983, 52881, 2398, 45449, 50289, and 52872, g protein-coupled receptors and uses therefor
|
ES2254042T3
(es)
|
2000-03-24 |
2008-03-16 |
Biosphere Medical, Inc. |
Microesferas para embolizacion activa.
|
ES2272461T3
(es)
|
2000-04-07 |
2007-05-01 |
Basf Plant Science Gmbh |
Proteinas proteina-quinasa relacionadas con el estres y metodos de utilizacion en las plantas.
|
EP1714661A3
(en)
|
2000-05-19 |
2012-03-14 |
The Center for Blood Research, INC. |
Methods for diagnosing and treating hemostatic disorders by modulating p-selectin activity
|
EP1297135B1
(en)
|
2000-06-28 |
2013-01-09 |
Genetics Institute, LLC |
Pd-l2 molecules: novel pd-1 ligands and uses therefor
|
DE60142356D1
(de)
|
2000-07-18 |
2010-07-22 |
Millennium Pharm Inc |
18480 humane proteinkinasemoleküle und ihre verwendungen
|
US6677500B2
(en)
|
2000-08-15 |
2004-01-13 |
Board Of Trustees Of The University Of Illinois |
Ungulates expressing exogenous IGF-I in their milk
|
WO2002018583A2
(en)
|
2000-09-01 |
2002-03-07 |
The Center For Blood Research, Inc. |
Modified polypeptides stabilized in a desired conformation and methods for producing same
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
US20040226053A1
(en)
*
|
2000-10-13 |
2004-11-11 |
Meade Harry M. |
Methods of producing a target molecule in a transgenic animal and purification of the target molecule
|
ES2338757T3
(es)
|
2000-10-18 |
2010-05-12 |
The Brigham And Women's Hospital, Inc. |
Polipeptidos ligandos para selectina-e/selectina-l de la celula hematopoyetica y metodos de utilizacion de los mismos.
|
EP1356108A2
(en)
|
2000-11-28 |
2003-10-29 |
Wyeth |
Expression analysis of fkbp nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
|
HUP0303905A3
(en)
|
2000-11-28 |
2005-11-28 |
Wyeth Corp |
Expression analysis of kiaa nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
|
DE60144493D1
(de)
|
2000-12-08 |
2011-06-01 |
Curagen Corp |
Verfahren zur bestimmung und behandlung von tuberöse-sklerose komplex assoziierten erkrankungen
|
US7247704B2
(en)
|
2000-12-18 |
2007-07-24 |
Arriva Pharmaceuticals, Inc. |
Multifunctional protease inhibitors and their use in treatment of disease
|
US8981061B2
(en)
|
2001-03-20 |
2015-03-17 |
Novo Nordisk A/S |
Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
|
US8231878B2
(en)
|
2001-03-20 |
2012-07-31 |
Cosmo Research & Development S.P.A. |
Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof
|
EP1379125A4
(en)
|
2001-03-22 |
2004-12-08 |
Abbott Gmbh & Co Kg |
TRANSGENIC ANIMALS THAT EXPRESS SPECIFIC ANTIBODIES FOR INTERESTING GENES AND THEIR USE
|
GB0107510D0
(en)
|
2001-03-26 |
2001-05-16 |
Univ Bristol |
New elongase gene and a process for the production of -9-polyunsaturated fatty acids
|
EP1383912A4
(en)
|
2001-04-02 |
2007-11-28 |
Wyeth Corp |
PD-1, A RECEPTOR FOR B7-4, AND USES THEREOF
|
EP1572868A4
(en)
|
2001-04-16 |
2007-04-04 |
Wyeth Corp |
NOVEL OPEN READING FRAMES OF STREPTOCOCCUS PNEUMONIAE ENCODING POLYPEPTIDE ANTIGENS AND USES THEREOF
|
WO2003014151A2
(en)
|
2001-08-10 |
2003-02-20 |
Genset S.A. |
Human secreted proteins, their encoding polynucleotides, and uses thereof
|
CA2459961A1
(en)
|
2001-09-05 |
2003-03-13 |
Basf Plant Science Gmbh |
Protein phosphatase stress-related polypeptides and methods of use in plants
|
US7776321B2
(en)
|
2001-09-26 |
2010-08-17 |
Mayo Foundation For Medical Education And Research |
Mutable vaccines
|
US6956114B2
(en)
|
2001-10-30 |
2005-10-18 |
'454 Corporation |
Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
|
US6902921B2
(en)
|
2001-10-30 |
2005-06-07 |
454 Corporation |
Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
|
DE10154180A1
(de)
|
2001-11-05 |
2003-05-15 |
Basf Ag |
gene die für genetische Stabilitäts-, genexpressions-und Faltungsproteine codieren
|
DE10154270A1
(de)
|
2001-11-05 |
2003-05-15 |
Basf Ag |
Gene die für Kohlenstoffmetabolismus- und Energieproduktion-Proteine codieren
|
US7220585B2
(en)
|
2001-11-09 |
2007-05-22 |
Basf Plant Science Gmbh |
Transcription factor stress-related polypeptides and methods of use in plants
|
EP1525323B1
(en)
|
2001-11-09 |
2015-01-21 |
Dana-Farber Cancer Institute, Inc. |
Pgc-1beta, a novel pgc-1 homologue and uses therefor
|
WO2003053363A2
(en)
|
2001-12-19 |
2003-07-03 |
Millennium Pharmaceuticals, Inc. |
Human diacylglycerol acyltransferase 2 (dgat2) family members and uses therefor
|
WO2005000193A2
(en)
|
2003-06-30 |
2005-01-06 |
Tel Aviv University Future Technology Development L.P. |
Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
|
US20040052928A1
(en)
|
2002-09-06 |
2004-03-18 |
Ehud Gazit |
Peptides and methods using same for diagnosing and treating amyloid-associated diseases
|
US7781396B2
(en)
|
2002-01-31 |
2010-08-24 |
Tel Aviv University Future Technology Development L.P. |
Peptides directed for diagnosis and treatment of amyloid-associated disease
|
WO2003078660A2
(en)
|
2002-03-18 |
2003-09-25 |
Yeda Research And Development Co. Ltd. |
Methods of identifying gene expression products resultant from alternative splicing and methods of diagnosing and treating disorders associated therewith
|
CN102793921A
(zh)
|
2002-04-09 |
2012-11-28 |
比奥根艾迪克Ma公司 |
用于治疗tweak 相关病症的方法
|
EP1572950B1
(en)
|
2002-06-17 |
2012-10-10 |
Thrasos, Inc. |
Single domain tdf-related compounds and analogs thereof
|
US7250551B2
(en)
|
2002-07-24 |
2007-07-31 |
President And Fellows Of Harvard College |
Transgenic mice expressing inducible human p25
|
CA2496272A1
(en)
|
2002-08-20 |
2004-03-04 |
Millennium Pharmaceuticals, Inc. |
Integrin b6 markers for compositions, kits, and methods for identification, assessment, prevention and therapy of cervical cancer
|
US20060009378A1
(en)
|
2002-11-14 |
2006-01-12 |
Itshak Golan |
Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases
|
EP2112229A3
(en)
|
2002-11-25 |
2009-12-02 |
Sequenom, Inc. |
Methods for identifying risk of breast cancer and treatments thereof
|
US7491699B2
(en)
|
2002-12-09 |
2009-02-17 |
Ramot At Tel Aviv University Ltd. |
Peptide nanostructures and methods of generating and using the same
|
EP2058275A1
(en)
|
2003-01-07 |
2009-05-13 |
Ramot at Tel-Aviv University Ltd. |
Peptide nanostructures encapsulating a foreign material and method of manufacturing same
|
WO2004078991A2
(en)
|
2003-03-04 |
2004-09-16 |
Yeda Research And Development Co. Ltd. |
Pon polypeptides, polynucleotides encoding same and compositions and methods utilizing same
|
EP1610678B1
(en)
|
2003-04-04 |
2011-07-27 |
Yeda Research And Development Co., Ltd. |
Antibodies for inhibiting the activity of mmp-2 and mmp-9
|
FR2853551B1
(fr)
|
2003-04-09 |
2006-08-04 |
Lab Francais Du Fractionnement |
Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
|
US7097993B2
(en)
|
2003-06-25 |
2006-08-29 |
Wisconsin Alumni Research Foundation |
Method for identifying an agent that modulates type 1 phosphatidylinositol phosphate kinase isoform β661 activity
|
EP3192872A1
(en)
|
2003-08-26 |
2017-07-19 |
The Regents of the University of Colorado, a body corporate |
Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
|
WO2005031362A2
(en)
|
2003-10-02 |
2005-04-07 |
Ramot At Tel Aviv University Ltd. |
Novel antibacterial agents and methods of identifying and utilizing same
|
WO2005034732A2
(en)
|
2003-10-07 |
2005-04-21 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
EP1959011B1
(en)
|
2003-10-24 |
2012-03-28 |
Selexis S.A. |
High efficiency gene transfer and expression in mammalian cells by a multiple transfection procedure of matrix attachment region sequences
|
IL158868A0
(en)
|
2003-11-13 |
2004-05-12 |
Yeda Res & Dev |
Methods of generating and using stem cells enriched with immature primitive progenitor
|
DE10359661A1
(de)
|
2003-12-18 |
2005-07-28 |
Basf Ag |
Genvarianten die für Proteine aus dem Stoffwechselweg von Feinchemikalien codieren
|
US8007847B2
(en)
|
2004-01-13 |
2011-08-30 |
Eytan Biderman |
Feeding formula appliance
|
US20050245444A1
(en)
*
|
2004-04-30 |
2005-11-03 |
Yann Echelard |
Method of using recombinant human antithrombin for neurocognitive disorders
|
WO2006009836A2
(en)
|
2004-06-17 |
2006-01-26 |
Thrasos Therapeutics, Inc. |
Tdf-related compounds and analogs thereof
|
US7288385B2
(en)
|
2004-06-25 |
2007-10-30 |
The Salk Institute For Biological Studies |
Increasing life span by modulation of Smek
|
EP1793816B1
(en)
|
2004-08-19 |
2012-01-04 |
Tel Aviv University Future Technology Development L.P. |
Compositions for treating amyloid associated diseases
|
US7893197B2
(en)
|
2004-08-25 |
2011-02-22 |
Janssen Pharmaceutica N.V. |
Relaxin-3 chimeric polypeptides and their preparation and use
|
CA2583121A1
(en)
|
2004-10-21 |
2007-01-04 |
Wyeth |
Immunogenic compositions of staphylococcus epidermidis polypeptide antigens
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
US20060121004A1
(en)
*
|
2004-12-07 |
2006-06-08 |
Yann Echelard |
Methods of reducing the incidence of rejection in tissue transplantation through the use of recombinant human antithrombin
|
CN1274829C
(zh)
|
2004-12-10 |
2006-09-13 |
四川大学华西医院 |
抗eb病毒所致肿瘤多肽及其应用与制备方法
|
EP1844403A4
(en)
|
2005-01-16 |
2010-06-23 |
Zlango Ltd |
SIGNS COMMUNICATION
|
US8019818B2
(en)
|
2005-01-18 |
2011-09-13 |
Zlango Ltd. |
Communications network system and methods for using same
|
US8226926B2
(en)
|
2005-05-09 |
2012-07-24 |
Biosphere Medical, S.A. |
Compositions and methods using microspheres and non-ionic contrast agents
|
US8124084B2
(en)
|
2005-05-17 |
2012-02-28 |
University Of Connecticut |
Compositions and methods for immunomodulation in an organism using IL-15 and soluble IL-15Ra
|
CN101203603B
(zh)
|
2005-06-17 |
2011-11-16 |
巴斯福植物科学有限公司 |
凝集素样蛋白激酶胁迫相关多肽和在植物内使用的方法
|
JP5383186B2
(ja)
|
2005-07-07 |
2014-01-08 |
イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム リミテッド |
H19をダウンレギュレートする核酸薬剤、及びそれを使用する方法
|
US20090186097A1
(en)
|
2005-08-09 |
2009-07-23 |
David Lee Ayares |
Transgenic Ungulates Expressing CTLA4-IG and Uses Thereof
|
US8299212B2
(en)
|
2005-09-20 |
2012-10-30 |
Thrasos Therapeutics, Inc. |
TDF-related compounds and analogs thereof, analogs and bioactive fragments
|
EP1937311A2
(en)
|
2005-09-30 |
2008-07-02 |
The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services |
Methods and compositions for modulating immune tolerance
|
IL172297A
(en)
|
2005-10-03 |
2016-03-31 |
Compugen Ltd |
Soluble vegfr-1 variants for the diagnosis of preeclampsia
|
ES2539616T3
(es)
|
2005-10-18 |
2015-07-02 |
Precision Biosciences |
Meganucleasa diseñada racionalmente con afinidad de formación de dímeros alterada
|
US7767420B2
(en)
|
2005-11-03 |
2010-08-03 |
Momenta Pharmaceuticals, Inc. |
Heparan sulfate glycosaminoglycan lyase and uses thereof
|
US20100184021A1
(en)
|
2006-01-16 |
2010-07-22 |
Compugen Ltd. |
Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis
|
WO2007080559A2
(en)
|
2006-01-16 |
2007-07-19 |
Zlango Ltd. |
Iconic communication
|
US8450269B2
(en)
|
2006-02-03 |
2013-05-28 |
Prolor Biotech Ltd. |
Long-acting growth hormone and methods of producing same
|
US10351615B2
(en)
|
2006-02-03 |
2019-07-16 |
Opko Biologics Ltd. |
Methods of treatment with long-acting growth hormone
|
US8048849B2
(en)
|
2006-02-03 |
2011-11-01 |
Modigene, Inc. |
Long-acting polypeptides and methods of producing same
|
US9249407B2
(en)
|
2006-02-03 |
2016-02-02 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US8946155B2
(en)
|
2006-02-03 |
2015-02-03 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US9458444B2
(en)
|
2006-02-03 |
2016-10-04 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US7553941B2
(en)
|
2006-02-03 |
2009-06-30 |
Modigene Inc |
Long-acting polypeptides and methods of producing same
|
US8048848B2
(en)
|
2006-02-03 |
2011-11-01 |
Prolor Biotech Ltd. |
Long-acting interferons and derivatives thereof and methods thereof
|
US20140113860A1
(en)
|
2006-02-03 |
2014-04-24 |
Prolor Biotech Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US8476234B2
(en)
|
2006-02-03 |
2013-07-02 |
Prolor Biotech Inc. |
Long-acting coagulation factors and methods of producing same
|
US20150038413A1
(en)
|
2006-02-03 |
2015-02-05 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US8759292B2
(en)
|
2006-02-03 |
2014-06-24 |
Prolor Biotech, Llc |
Long-acting coagulation factors and methods of producing same
|
US10221228B2
(en)
|
2006-02-03 |
2019-03-05 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
JP2009543544A
(ja)
|
2006-05-15 |
2009-12-10 |
パラテック ファーマシューティカルズ インコーポレイテッド |
置換されたテトラサイクリン化合物を用いて、遺伝子または遺伝子産物の発現を調節する方法
|
FR2901707B1
(fr)
|
2006-05-31 |
2017-09-29 |
Lab Francais Du Fractionnement |
Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis
|
CA2654165A1
(en)
|
2006-06-05 |
2007-12-13 |
Cancer Care Ontario |
Assessment of risk for colorectal cancer
|
EP2037737B1
(en)
|
2006-07-11 |
2014-04-02 |
University Of Medicine And Dentistry Of New Jersey |
Cell membrane repair proteins, nucleic acids encoding the same and associated methods of use
|
FR2904558B1
(fr)
*
|
2006-08-01 |
2008-10-17 |
Lab Francais Du Fractionnement |
"composition de facteur vii recombinant ou transgenique, presentant majoritairement des formes glycanniques biantennees, bisialylees et non fucosylees"
|
US9277737B2
(en)
|
2006-09-21 |
2016-03-08 |
Probiodrug Ag |
Mouse models carrying a knock-out mutation of the QPCTL-gene
|
CN105061580B
(zh)
|
2006-10-03 |
2020-06-05 |
罗格斯新泽西州立大学 |
多肽和药物组合物及其应用
|
FR2910969B1
(fr)
*
|
2006-12-29 |
2009-02-27 |
Lab Francais Du Fractionnement |
Procede de mesure de la concentration de facteur viia (fviia) dans un echantillon
|
FR2910786B1
(fr)
|
2006-12-29 |
2017-08-11 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies (Lfb) |
"procede d'extraction d'une proteine presente dans du lait"
|
WO2008087642A2
(en)
|
2007-01-16 |
2008-07-24 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Nucleic acid constructs and methods for specific silencing of h19
|
DK2121944T3
(da)
|
2007-01-19 |
2011-10-31 |
Probiodrug Ag |
In vivo screeningsmodeller til behandling af Alzheimers sygdom og andre QPCT-relaterede lidelser
|
FR2912310B1
(fr)
|
2007-02-13 |
2009-08-07 |
Kasan Sarl |
Nouvelles compositions cosmetiques et/ou pharmaceutiques et leurs applications.
|
EP2079839A4
(en)
|
2007-03-05 |
2009-11-18 |
Cancer Care Ontario |
ASSESSMENT OF COLORECTAL CARCINOMA RISK
|
EP2134365B1
(en)
|
2007-03-21 |
2019-03-13 |
Effat Emamian |
Compositions and methods for inhibiting tumor cell growth
|
US9556210B2
(en)
|
2007-04-23 |
2017-01-31 |
Sabag-Rfa Ltd. |
System for delivering therapeutic agents into living cells and cells nuclei
|
WO2008129548A2
(en)
|
2007-04-23 |
2008-10-30 |
Segev Laboratories Limited |
A system for delivering therapeutic agents into living cells and cells nuclei
|
WO2014064687A1
(en)
|
2012-10-22 |
2014-05-01 |
Deliversir Ltd |
A system for delivering therapeutic agents into living cells and cells nuclei
|
US9156865B2
(en)
|
2007-04-23 |
2015-10-13 |
Deliversir Ltd |
System for delivering therapeutic agents into living cells and cells nuclei
|
FR2917414B1
(fr)
*
|
2007-06-15 |
2012-07-13 |
Lab Francais Du Fractionnement |
Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci
|
EP2182943B1
(en)
|
2007-07-23 |
2016-10-26 |
Janssen Biotech, Inc. |
Methods and compositions for treating fibrosis related disorders using il-17 antagonists
|
FR2920024B1
(fr)
|
2007-08-14 |
2012-12-14 |
Lfb Biotechnologies |
Procede de purification ou de detection d'une proteine cible
|
JP5607530B2
(ja)
|
2007-09-04 |
2014-10-15 |
コンピュゲン エルティーディー. |
ポリペプチド並びにポリヌクレオチド、並びに薬剤および生物製剤生産のための薬剤標的としてのその利用
|
JP2011501652A
(ja)
|
2007-09-12 |
2011-01-13 |
プロビオドルグ エージー |
トランスジェニックマウス
|
US8663980B2
(en)
|
2007-10-26 |
2014-03-04 |
Janssen Biotech, Inc. |
Vectors, host cells, and methods of production and uses
|
ES2422291T3
(es)
|
2007-10-31 |
2013-09-10 |
Prec Biosciences Inc |
Meganucleasas monocatenarias diseñadas racionalmente con secuencias de reconocimiento no palindrómicas
|
US8501449B2
(en)
|
2007-12-04 |
2013-08-06 |
Proteon Therapeutics, Inc. |
Recombinant elastase proteins and methods of manufacturing and use thereof
|
US9462793B2
(en)
|
2008-01-14 |
2016-10-11 |
Probiodrug Ag |
Mouse carrying a knock-out mutation of the Qpct-gene
|
JP2011525113A
(ja)
|
2008-06-20 |
2011-09-15 |
ワイス・エルエルシー |
β−溶血性連鎖球菌株由来のORF1358の組成物および使用方法
|
FR2933496B1
(fr)
*
|
2008-07-02 |
2012-10-05 |
Lfb Biotechnologies |
Procede de mesure du taux de facteur vii active dans un echantillon
|
US8999661B2
(en)
|
2008-07-30 |
2015-04-07 |
Dana-Farber Cancer Institute, Inc. |
Compositions for detecting cell death and methods of use thereof
|
EP2330896B1
(en)
|
2008-09-10 |
2015-11-25 |
Ben Gurion University Of The Negev Research And Development Authority |
Antinecrotic activity of alpha 1-antitrypsin
|
US8962247B2
(en)
|
2008-09-16 |
2015-02-24 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
|
US8476013B2
(en)
|
2008-09-16 |
2013-07-02 |
Sequenom, Inc. |
Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
SI2342226T1
(sl)
|
2008-09-26 |
2016-11-30 |
Dana-Farber Cancer Institute Inc. |
Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe
|
SMT202000101T1
(it)
|
2008-10-10 |
2020-03-13 |
Childrens Medical Center |
Vaccino con trimero di env di hiv-1 stabilizzato biochimicamente
|
WO2010061393A1
(en)
|
2008-11-30 |
2010-06-03 |
Compugen Ltd. |
He4 variant nucleotide and amino acid sequences, and methods of use thereof
|
WO2010064231A1
(en)
|
2008-12-02 |
2010-06-10 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Methods of analyzing a-i rna editing and nucleic acid constructs capable of same
|
US8734759B2
(en)
|
2008-12-05 |
2014-05-27 |
Yeda Research And Development Co. Ltd. |
Methods of diagnosing and treating motor neuron diseases
|
FR2940655B1
(fr)
|
2008-12-31 |
2011-02-18 |
Lfb Biotechnologies |
Peptides isoles de facteur vii de lapin.
|
US9181315B2
(en)
|
2009-01-08 |
2015-11-10 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for induced brown fat differentiation
|
WO2010088522A2
(en)
|
2009-01-30 |
2010-08-05 |
Ab Biosciences, Inc. |
Novel lowered affinity antibodies and uses therefor
|
FR2942231B1
(fr)
|
2009-02-19 |
2015-03-20 |
Lfb Biotechnologies |
Acides nucleiques se liant specifiquement au facteur vii/viia humain, et utilisations
|
FR2942232B1
(fr)
|
2009-02-19 |
2015-03-13 |
Lfb Biotechnologies |
Moyens pour la purification d'une proteine de la coagulation et procedes pour sa mise en oeuvre
|
US9023767B2
(en)
|
2009-05-07 |
2015-05-05 |
Memorial Sloan-Kettering Cancer Center |
γ-Secretase substrates and methods of use
|
FR2947181B1
(fr)
|
2009-06-26 |
2012-05-04 |
Lfb Biotechnologies |
Composition de facteur vii
|
US12203113B2
(en)
|
2009-07-09 |
2025-01-21 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US9663778B2
(en)
|
2009-07-09 |
2017-05-30 |
OPKO Biologies Ltd. |
Long-acting coagulation factors and methods of producing same
|
FR2948665B1
(fr)
|
2009-07-31 |
2011-09-23 |
Lfb Biotechnologies |
Procede pour la purification de proteines de la coagulation a domaine gla actives
|
FR2948664B1
(fr)
|
2009-07-31 |
2013-11-01 |
Lfb Biotechnologies |
Procede pour la purification de proteines de la coagulation a domaine gla
|
US9642817B2
(en)
|
2009-08-27 |
2017-05-09 |
Technion Research & Development Foundation Limited |
Liposomal compositions and uses of same
|
EP3168232B1
(en)
|
2009-11-13 |
2021-09-29 |
Dana-Farber Cancer Institute, Inc. |
Compositions, kits, and methods for the diagnosis, prognosis, monitoring, treatment and modulation of post-transplant lymphoproliferative disorders and hypoxia associated angiogenesis disorders using galectin-1
|
EP3660165B1
(en)
|
2009-12-22 |
2023-01-04 |
Sequenom, Inc. |
Processes and kits for identifying aneuploidy
|
WO2011088163A1
(en)
|
2010-01-14 |
2011-07-21 |
President And Fellows Of Harvard College |
Methods for modulating skeletal remodeling and patterning by modulating shn2 activity, shn3 activity, or shn2 and shn3 activity in combination
|
US10429384B2
(en)
|
2010-01-22 |
2019-10-01 |
Dana-Farber Cancer Institute, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of metabolic disorders
|
EP2528949A1
(en)
|
2010-01-27 |
2012-12-05 |
Yeda Research And Development Co. Ltd. |
Antibodies that inhibit metalloproteins
|
CN102971342B
(zh)
|
2010-01-28 |
2016-08-03 |
Ab生物科学公司 |
亲和力降低的新抗体和制备所述抗体的方法
|
TWI518325B
(zh)
|
2010-02-04 |
2016-01-21 |
自治醫科大學 |
對alk抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
|
US20130109615A1
(en)
|
2010-02-24 |
2013-05-02 |
Ben Gurion University Of The Negev Research And Development Authority |
Methods for inhibiting necrosis
|
US8861162B2
(en)
*
|
2010-03-09 |
2014-10-14 |
Honeywell International Inc. |
High power solid state power controller (SSPC) solution for primary power distribution applications
|
AU2011230537C1
(en)
|
2010-03-26 |
2018-08-02 |
Trustees Of Dartmouth College |
Vista regulatory T cell mediator protein, vista binding agents and use thereof
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
WO2011133288A1
(en)
|
2010-04-19 |
2011-10-27 |
The Trustees Of The University Of Pennsylvania |
Microrna induction of pluripotential stem cells and uses thereof
|
KR20130036276A
(ko)
|
2010-06-22 |
2013-04-11 |
더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 |
보체 결합 3의 C3d 조각에 대한 항체들
|
CN103068399A
(zh)
|
2010-06-30 |
2013-04-24 |
卡姆普根有限公司 |
用于治疗多发性硬化、类风湿性关节炎以及其他自身免疫病症的c1orf32
|
JP2013541938A
(ja)
|
2010-09-02 |
2013-11-21 |
プロビオドルグ エージー |
アイソqc関連障害の治療のためのインビボスクリーニングモデル
|
US9632088B2
(en)
|
2010-09-07 |
2017-04-25 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for gamma-secretase assay
|
WO2012046238A2
(en)
|
2010-10-06 |
2012-04-12 |
Ramot At Tel-Aviv University Ltd. |
Erythropoietin receptor antagonists
|
WO2012051301A1
(en)
|
2010-10-12 |
2012-04-19 |
President And Fellows Of Harvard College |
Methods for identifying modulators of triglyceride metabolism, for modulating triglyceride metabolism and for identifying subjects at risk for abnormal triglyceride metabolism
|
WO2012052878A1
(en)
|
2010-10-19 |
2012-04-26 |
Vascular Biogenics Ltd. |
Isolated polynucleotides and nucleic acid constructs for directing expression of a gene-of-interest in cells
|
US9539427B2
(en)
|
2010-11-08 |
2017-01-10 |
The Johns Hopkins University |
Methods for improving heart function
|
FR2967071A1
(fr)
|
2010-11-10 |
2012-05-11 |
Lab Francais Du Fractionnement |
Facteur h pour le traitement de maladies auto-immunes du systeme nerveux
|
WO2012066549A1
(en)
|
2010-11-15 |
2012-05-24 |
Ramot At Tel-Aviv University Ltd. |
Dipeptide analogs for treating conditions associated with amyloid fibril formation
|
WO2012090067A1
(en)
|
2010-12-30 |
2012-07-05 |
Lfb Biotechnologies |
Glycols as pathogen inactivating agents
|
NZ713461A
(en)
|
2011-04-15 |
2017-02-24 |
Compugen Ltd |
Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
|
WO2012156976A1
(en)
|
2011-05-16 |
2012-11-22 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Methods of producing artemisinin in non-host plants and vectors for use in same
|
WO2012156535A1
(en)
|
2011-05-19 |
2012-11-22 |
Fundación Progreso Y Salud |
Highly inducible dual-promoter lentiviral tet-on system
|
US9067997B2
(en)
|
2011-05-25 |
2015-06-30 |
Innate Pharma Sa |
Anti-KIR antibodies for the treatment of inflammatory and autoimmune disorders
|
CA2836855C
(en)
|
2011-06-30 |
2020-07-14 |
Compugen Ltd. |
Polypeptides and uses thereof for treatment of autoimmune disorders and infection
|
EP2734621B1
(en)
|
2011-07-22 |
2019-09-04 |
President and Fellows of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
WO2013017555A1
(en)
|
2011-08-01 |
2013-02-07 |
Lfb-Biotechnologies |
Factor vii compositions with specific glycosylation for controlled half-life
|
EP2742062A2
(en)
|
2011-08-12 |
2014-06-18 |
Probiodrug AG |
In vivo screening models for treatment of qc-related disorders
|
AU2012298884B2
(en)
|
2011-08-23 |
2017-11-16 |
Foundation Medicine, Inc. |
Novel KIF5B-RET fusion molecules and uses thereof
|
CA2848368C
(en)
|
2011-09-13 |
2023-02-14 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for brown fat induction and activity using fndc5
|
US10378060B2
(en)
|
2011-10-14 |
2019-08-13 |
Dana-Farber Cancer Institute, Inc. |
ZNF365/ZFP365 biomarker predictive of anti-cancer response
|
WO2013056178A2
(en)
|
2011-10-14 |
2013-04-18 |
Foundation Medicine, Inc. |
Novel estrogen receptor mutations and uses thereof
|
FR2983212A1
(fr)
|
2011-11-28 |
2013-05-31 |
Lfb Biotechnologies |
Aptameres anti-fh, procede pour leur obtention et utilisations
|
ES2894724T3
(es)
|
2011-12-02 |
2022-02-15 |
Rhode Island Hospital |
Vacuna contra la malaria falciparum
|
WO2013114363A2
(en)
|
2012-01-30 |
2013-08-08 |
Yeda Research And Development Co.Ltd. |
Antimicrobial agents
|
BR112014018481A2
(pt)
|
2012-02-01 |
2017-07-04 |
Compugen Ltd |
anticorpo monoclonal ou policlonal ou um fragmento de ligação a antígeno do mesmo, polinucleotídeo, anticorpo monoclonal, vetor, hibridoma, anticorpo, hibridoma 5166-2 e/ou 5166-9, anticorpo ou fragmento de ligação a antígeno, composição farmacêutica, uso do anticorpo ou fragmento de ligação a anticorpo, método para tratar câncer, método para diagnosticar câncer em um indivíduo, anticorpo, método, composição ou uso
|
CN104427994A
(zh)
|
2012-02-14 |
2015-03-18 |
奥普科生物制品有限公司 |
长效凝血因子和生产它们的方法
|
SMT201800620T1
(it)
|
2012-02-15 |
2019-01-11 |
Novo Nordisk As |
Anticorpi che legano la proteina di riconoscimento dei peptidoglicani 1
|
US9550830B2
(en)
|
2012-02-15 |
2017-01-24 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
|
SMT201700488T1
(it)
|
2012-02-15 |
2017-11-15 |
Novo Nordisk As |
Anticorpi che legano e bloccano il recettore d'innesco espresso sulle cellule mieloidi-1 (trem-1)
|
EP4155401A1
(en)
|
2012-03-02 |
2023-03-29 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
TW201400499A
(zh)
|
2012-03-12 |
2014-01-01 |
Revo Biolog Inc |
抗凝血酶用於治療妊娠毒血症之用途
|
US9494597B2
(en)
|
2012-04-02 |
2016-11-15 |
Ab Biosciences, Inc. |
Human control antibodies and uses therefor
|
BR112014025951A2
(pt)
|
2012-04-19 |
2017-07-11 |
Opko Biologics Ltd |
variantes de oxintomodulina de longa ação e métodos de produção do mesmo
|
US9920361B2
(en)
|
2012-05-21 |
2018-03-20 |
Sequenom, Inc. |
Methods and compositions for analyzing nucleic acid
|
US10504613B2
(en)
|
2012-12-20 |
2019-12-10 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
EP2855521A4
(en)
|
2012-05-24 |
2016-03-02 |
Mountgate Group Ltd |
COMPOSITIONS AND METHODS ASSOCIATED WITH THE PREVENTION AND TREATMENT OF RABIC INFECTION
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
TWI705073B
(zh)
|
2012-06-22 |
2020-09-21 |
達特茅斯學院基金會 |
新穎之vista-ig構築體及vista-ig用於治療自體免疫、過敏及發炎病症之用途
|
AU2013290102B2
(en)
|
2012-07-13 |
2018-11-15 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
JP6389172B2
(ja)
|
2012-08-03 |
2018-09-12 |
エルエフビー ユーエスエー インコーポレイテッドLfb Usa, Inc. |
体外式膜型人工肺におけるアンチトロンビンの使用
|
AU2013312211B2
(en)
|
2012-09-07 |
2018-03-29 |
King's College London |
VISTA modulators for diagnosis and treatment of cancer
|
EP2914621B1
(en)
|
2012-11-05 |
2023-06-07 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
AU2013349239B2
(en)
|
2012-11-20 |
2018-04-12 |
Opko Biologics Ltd. |
Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides
|
US20140242664A1
(en)
|
2012-12-12 |
2014-08-28 |
The Broad Institute, Inc. |
Engineering of systems, methods and optimized guide compositions for sequence manipulation
|
CN114634950A
(zh)
|
2012-12-12 |
2022-06-17 |
布罗德研究所有限公司 |
用于序列操纵的crispr-cas组分系统、方法以及组合物
|
WO2014093701A1
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
PL2931898T3
(pl)
|
2012-12-12 |
2016-09-30 |
Le Cong |
Projektowanie i optymalizacja systemów, sposoby i kompozycje do manipulacji sekwencją z domenami funkcjonalnymi
|
SG10201912328UA
(en)
|
2012-12-12 |
2020-02-27 |
Broad Inst Inc |
Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications
|
SG10201912327SA
(en)
|
2012-12-12 |
2020-02-27 |
Broad Inst Inc |
Engineering and Optimization of Improved Systems, Methods and Enzyme Compositions for Sequence Manipulation
|
EP2896697B1
(en)
|
2012-12-12 |
2015-09-02 |
The Broad Institute, Inc. |
Engineering of systems, methods and optimized guide compositions for sequence manipulation
|
US20140310830A1
(en)
|
2012-12-12 |
2014-10-16 |
Feng Zhang |
CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes
|
ES2701749T3
(es)
|
2012-12-12 |
2019-02-25 |
Broad Inst Inc |
Métodos, modelos, sistemas y aparatos para identificar secuencias diana para enzimas Cas o sistemas CRISPR-Cas para secuencias diana y transmitir resultados de los mismos
|
WO2014113729A2
(en)
|
2013-01-18 |
2014-07-24 |
Foundation Mecicine, Inc. |
Methods of treating cholangiocarcinoma
|
AR094778A1
(es)
|
2013-02-13 |
2015-08-26 |
Laboratoire Français Du Fractionnement Et Des Biotechnologies |
Proteínas con glicosilación modificada y métodos para producirlas
|
BR112015019341A2
(pt)
|
2013-02-13 |
2017-08-22 |
Lab Francais Du Fractionnement |
Anticorpo anti-tnf-alfa, composição que compreende o anticorpo, método para produzir uma população de anticorpos, células epiteliais da glândula mamária, mamífero não humano transgênico, e, composição de anticorpo anti-tnf monoclonal
|
EP2971100A1
(en)
|
2013-03-13 |
2016-01-20 |
Sequenom, Inc. |
Primers for dna methylation analysis
|
FR3005576B1
(fr)
|
2013-05-15 |
2015-06-19 |
Lab Francais Du Fractionnement |
Procede d'inactivation d'une proteine prion
|
JP6650393B2
(ja)
|
2013-06-13 |
2020-02-19 |
オージェネシス リミテッド |
細胞の集団、分化転換の方法及びその使用方法
|
RU2716421C2
(ru)
|
2013-06-17 |
2020-03-11 |
Те Брод Инститьют Инк. |
Доставка, применение и применения в терапии систем crispr-cas и композиций для целенаправленного воздействия на нарушения и заболевания с использованием вирусных компонентов
|
EP3620524A1
(en)
|
2013-06-17 |
2020-03-11 |
The Broad Institute, Inc. |
Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells
|
EP3011029B1
(en)
|
2013-06-17 |
2019-12-11 |
The Broad Institute, Inc. |
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
|
CN105492611A
(zh)
|
2013-06-17 |
2016-04-13 |
布罗德研究所有限公司 |
用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物
|
WO2014204727A1
(en)
|
2013-06-17 |
2014-12-24 |
The Broad Institute Inc. |
Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof
|
DK3011031T3
(da)
|
2013-06-17 |
2020-12-21 |
Broad Inst Inc |
Fremføring og anvendelse af crispr-cas-systemerne, vektorer og sammensætninger til levermålretning og -terapi
|
CN105358228A
(zh)
|
2013-07-05 |
2016-02-24 |
法国血液分割暨生化制品实验室 |
亲和层析基质
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
US9340800B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
Extended DNA-sensing GRNAS
|
FR3011250A1
(fr)
|
2013-09-30 |
2015-04-03 |
Lab Francais Du Fractionnement |
Acides nucleiques se liant specifiquement au facteur ix/ixa humain, et utilisations
|
US20150158926A1
(en)
|
2013-10-21 |
2015-06-11 |
Opko Biologics, Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
AU2014338575B2
(en)
|
2013-10-21 |
2019-11-07 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
WO2015065964A1
(en)
|
2013-10-28 |
2015-05-07 |
The Broad Institute Inc. |
Functional genomics using crispr-cas systems, compositions, methods, screens and applications thereof
|
FR3012453B1
(fr)
|
2013-10-31 |
2015-11-13 |
Lab Francais Du Fractionnement |
Proteine chimerique dans le traitement de l’amylose
|
EP2876114A1
(en)
|
2013-11-25 |
2015-05-27 |
Consejo Superior De Investigaciones Científicas |
Antibodies against CCR9 and applications thereof
|
WO2015089473A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
|
EP3080258A1
(en)
|
2013-12-12 |
2016-10-19 |
The Broad Institute, Inc. |
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
|
JP6793547B2
(ja)
|
2013-12-12 |
2020-12-02 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
最適化機能CRISPR−Cas系による配列操作のための系、方法および組成物
|
US20150166985A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting von willebrand factor point mutations
|
BR112016013213A2
(pt)
|
2013-12-12 |
2017-12-05 |
Massachusetts Inst Technology |
administração, uso e aplicações terapêuticas dos sistemas crispr-cas e composições para visar distúrbios e doenças usando componentes de administração de partículas
|
DK3079725T3
(da)
|
2013-12-12 |
2020-01-20 |
Broad Inst Inc |
Administration, brug og terapeutiske anvendelser af crispr-cas-systemerne og sammensætninger til genomredigering
|
KR20160089530A
(ko)
|
2013-12-12 |
2016-07-27 |
더 브로드 인스티튜트, 인코퍼레이티드 |
Hbv 및 바이러스 질병 및 질환을 위한 crisprcas 시스템 및 조성물의 전달,용도 및 치료적 적용
|
WO2015089364A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Crystal structure of a crispr-cas system, and uses thereof
|
SG10201912797XA
(en)
|
2013-12-24 |
2020-02-27 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
EP3117011B1
(en)
|
2014-03-13 |
2020-05-06 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
AU2015249374A1
(en)
|
2014-04-24 |
2016-12-01 |
Dana-Farber Cancer Institute, Inc. |
Tumor suppressor and oncogene biomarkers predictive of anti-immune checkpoint inhibitor response
|
EP3143123B1
(en)
|
2014-05-16 |
2019-11-27 |
The Trustees Of The University Of Pennsylvania |
Microrna induction of cardiac regeneration
|
MX2016016310A
(es)
|
2014-06-11 |
2017-10-20 |
A Green Kathy |
Uso de agonistas y antagonistas vista para suprimir o aumentar la inmunidad humoral.
|
SG10202002486QA
(en)
|
2014-06-16 |
2020-04-29 |
Univ Johns Hopkins |
Compositions and methods for the expression of crispr guide rnas using the h1 promoter
|
FR3022462B1
(fr)
|
2014-06-18 |
2018-04-27 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Composition orale d'anticorps anti-tnfalpha
|
KR102465120B1
(ko)
|
2014-07-17 |
2022-11-10 |
노보 노르디스크 에이/에스 |
점도를 감소시키기 위한 trem-1 항체의 부위 지정 돌연변이유발
|
EP4079847A1
(en)
|
2014-07-30 |
2022-10-26 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
WO2016028682A1
(en)
|
2014-08-17 |
2016-02-25 |
The Broad Institute Inc. |
Genome editing using cas9 nickases
|
US20170275344A1
(en)
|
2014-08-26 |
2017-09-28 |
Compugen Ltd. |
Polypeptides and uses thereof as a drug for treatment of autoimmune disorders
|
WO2016049251A1
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling mutations in leukocytes
|
WO2016049163A2
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Use and production of chd8+/- transgenic animals with behavioral phenotypes characteristic of autism spectrum disorder
|
WO2016049258A2
(en)
|
2014-09-25 |
2016-03-31 |
The Broad Institute Inc. |
Functional screening with optimized functional crispr-cas systems
|
AU2015328411C1
(en)
|
2014-10-06 |
2022-03-03 |
Dana-Farber Cancer Institute, Inc. |
Angiopoietin-2 biomarkers predictive of anti-immune checkpoint response
|
CN107405398A
(zh)
|
2014-12-05 |
2017-11-28 |
伊穆奈克斯特股份有限公司 |
鉴定vsig8作为推定vista受体及其用以产生vista/vsig8激动剂和拮抗剂的用途
|
WO2016092550A2
(en)
|
2014-12-10 |
2016-06-16 |
Opko Biologics Ltd. |
Methods of producing long acting ctp-modified polypeptides
|
EP3230452A1
(en)
|
2014-12-12 |
2017-10-18 |
The Broad Institute Inc. |
Dead guides for crispr transcription factors
|
EP3230451B1
(en)
|
2014-12-12 |
2021-04-07 |
The Broad Institute, Inc. |
Protected guide rnas (pgrnas)
|
WO2016094880A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of crispr systems and compositions for genome editing as to hematopoietic stem cells (hscs)
|
WO2016094874A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Escorted and functionalized guides for crispr-cas systems
|
EP3234192B1
(en)
|
2014-12-19 |
2021-07-14 |
The Broad Institute, Inc. |
Unbiased identification of double-strand breaks and genomic rearrangement by genome-wide insert capture sequencing
|
WO2016106236A1
(en)
|
2014-12-23 |
2016-06-30 |
The Broad Institute Inc. |
Rna-targeting system
|
CA2970370A1
(en)
|
2014-12-24 |
2016-06-30 |
Massachusetts Institute Of Technology |
Crispr having or associated with destabilization domains
|
MA41296A
(fr)
|
2014-12-30 |
2017-11-07 |
Orgenesis Ltd |
Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
|
WO2016108926A1
(en)
|
2014-12-30 |
2016-07-07 |
The Broad Institute Inc. |
Crispr mediated in vivo modeling and genetic screening of tumor growth and metastasis
|
EP3265825A4
(en)
|
2015-03-06 |
2018-08-08 |
Dana-Farber Cancer Institute, Inc. |
Pd-l2 biomarkers predictive of pd-1 pathway inhibitor responses in esophagogastric cancers
|
EP3273971A4
(en)
|
2015-03-27 |
2018-12-05 |
Yeda Research and Development Co. Ltd. |
Methods of treating motor neuron diseases
|
FR3034669B1
(fr)
|
2015-04-07 |
2020-02-14 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Nouvelle utilisation du facteur von willebrand
|
EP3294280A1
(en)
|
2015-05-11 |
2018-03-21 |
Yeda Research and Development Co., Ltd. |
Citrin inhibitors for the treatment of cancer
|
WO2016185457A1
(en)
|
2015-05-19 |
2016-11-24 |
Yeda Research And Development Co. Ltd. |
Methods of promoting lymphangiogenesis
|
NL2014935B1
(en)
|
2015-06-08 |
2017-02-03 |
Applied Immune Tech Ltd |
T cell receptor like antibodies having fine specificity.
|
US20180169297A1
(en)
|
2015-06-12 |
2018-06-21 |
Laboratoire Français Du Fractionnement Et Des Biotechnologies |
Injectable composition of factor vii and fillers
|
WO2016205728A1
(en)
|
2015-06-17 |
2016-12-22 |
Massachusetts Institute Of Technology |
Crispr mediated recording of cellular events
|
WO2016205745A2
(en)
*
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Cell sorting
|
AU2016279062A1
(en)
|
2015-06-18 |
2019-03-28 |
Omar O. Abudayyeh |
Novel CRISPR enzymes and systems
|
US9790490B2
(en)
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
EP3430134B1
(en)
|
2015-06-18 |
2022-09-21 |
The Broad Institute, Inc. |
Novel crispr enzymes and systems
|
US10960058B2
(en)
|
2015-06-19 |
2021-03-30 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
CN107922497B
(zh)
|
2015-06-24 |
2022-04-12 |
詹森药业有限公司 |
抗vista抗体和片段
|
WO2017024317A2
(en)
|
2015-08-06 |
2017-02-09 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce targeted protein degradation through bifunctional molecules
|
EP3334449B1
(en)
|
2015-08-10 |
2021-09-29 |
The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center |
Methods and pharmaceutical compositions for improving wound healing using cd24
|
AU2016342038B2
(en)
|
2015-10-22 |
2022-09-08 |
Massachusetts Institute Of Technology |
Type VI-B CRISPR enzymes and systems
|
EP3365357B1
(en)
|
2015-10-23 |
2024-02-14 |
President and Fellows of Harvard College |
Evolved cas9 proteins for gene editing
|
CA3002676A1
(en)
|
2015-10-29 |
2017-05-04 |
Dana-Farber Cancer Institute, Inc. |
Methods for identification, assessment, prevention, and treatment of metabolic disorders using pm20d1 and n-lipidated amino acids
|
IL289849B2
(en)
|
2015-11-10 |
2024-01-01 |
Nat Inst Biotechnology Negev Ltd |
Means and methods for reducing tumorigenicity of cancer stem cells
|
US12110490B2
(en)
|
2015-12-18 |
2024-10-08 |
The Broad Institute, Inc. |
CRISPR enzymes and systems
|
WO2017137830A1
(en)
|
2016-02-12 |
2017-08-17 |
Janssen Pharmaceutica Nv |
Anti-vista (b7h5) antibodies
|
WO2017138008A2
(en)
|
2016-02-14 |
2017-08-17 |
Yeda Research And Development Co. Ltd. |
Methods of modulating protein exocytosis and uses of same in therapy
|
US20190083642A1
(en)
|
2016-03-30 |
2019-03-21 |
Regentis Biomaterials Ltd. |
Treatments utilizing a polymer-protein conjugate
|
UA125382C2
(uk)
|
2016-04-15 |
2022-03-02 |
Імьюнекст Інк. |
Антитіла проти людського vista та їх застосування
|
CA3026110A1
(en)
|
2016-04-19 |
2017-11-02 |
The Broad Institute, Inc. |
Novel crispr enzymes and systems
|
WO2017184786A1
(en)
|
2016-04-19 |
2017-10-26 |
The Broad Institute Inc. |
Cpf1 complexes with reduced indel activity
|
KR102424476B1
(ko)
|
2016-04-19 |
2022-07-25 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신규한 crispr 효소 및 시스템
|
US11708588B2
(en)
|
2016-06-16 |
2023-07-25 |
Adam Brian Robertson |
Gene editing
|
AU2017283713B2
(en)
|
2016-06-17 |
2021-04-08 |
Massachusetts Institute Of Technology |
Type VI CRISPR orthologs and systems
|
US20210222164A1
(en)
|
2016-06-29 |
2021-07-22 |
The Broad Institute, Inc. |
Crispr-cas systems having destabilization domain
|
EP3481855B1
(en)
|
2016-07-11 |
2023-09-06 |
OPKO Biologics Ltd. |
Long-acting coagulation factor vii and methods of producing same
|
CA3030534A1
(en)
|
2016-07-11 |
2018-01-18 |
The National Institute For Biotechnology In The Negev, Ltd. |
Fusion proteins with extended serum half life
|
WO2018013720A1
(en)
|
2016-07-12 |
2018-01-18 |
Washington University |
Incorporation of internal polya-encoded poly-lysine sequence tags and their variations for the tunable control of protein synthesis in bacterial and eukaryotic cells
|
WO2018015881A1
(en)
|
2016-07-18 |
2018-01-25 |
Ramot At Tel-Aviv University Ltd. |
Modular platform for targeted therapeutics
|
FR3054444A1
(fr)
|
2016-07-29 |
2018-02-02 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Composition orale d'anticorps anti-tnf alpha
|
IL308426A
(en)
|
2016-08-03 |
2024-01-01 |
Harvard College |
Adenosine nuclear base editors and their uses
|
US11661590B2
(en)
|
2016-08-09 |
2023-05-30 |
President And Fellows Of Harvard College |
Programmable CAS9-recombinase fusion proteins and uses thereof
|
US11352647B2
(en)
|
2016-08-17 |
2022-06-07 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
CN110312799A
(zh)
|
2016-08-17 |
2019-10-08 |
博德研究所 |
新型crispr酶和系统
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
JP2020501506A
(ja)
|
2016-09-07 |
2020-01-23 |
イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー. |
抗NKp46抗体およびその治療的使用
|
WO2018057618A1
(en)
|
2016-09-20 |
2018-03-29 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of aml using usp10 biomarkers and modulators
|
GB2573062A
(en)
|
2016-10-14 |
2019-10-23 |
Harvard College |
AAV delivery of nucleobase editors
|
WO2018074979A1
(en)
|
2016-10-17 |
2018-04-26 |
Nanyang Technological University |
Truncated crispr-cas proteins for dna targeting
|
EP3545095A1
(en)
|
2016-11-28 |
2019-10-02 |
Yeda Research and Development Co., Ltd. |
Isolated polynucleotides and polypeptides and methods of using same for expressing an expression product of interest
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
CN110177878B
(zh)
|
2016-12-29 |
2023-11-03 |
Asc治疗公司 |
转基因动物和生物生产方法
|
HUE057326T2
(hu)
|
2017-01-05 |
2022-04-28 |
Kahr Medical Ltd |
SIRP1 Alfa-41 BBL fúziós fehérje és eljárások annak alkalmazására
|
HRP20230937T1
(hr)
|
2017-01-05 |
2023-11-24 |
Kahr Medical Ltd. |
Pd1-41bbl fuzijski protein i metode korištenja istog
|
WO2018165504A1
(en)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
EP3592777A1
(en)
|
2017-03-10 |
2020-01-15 |
President and Fellows of Harvard College |
Cytosine to guanine base editor
|
CN110959039A
(zh)
|
2017-03-15 |
2020-04-03 |
博德研究所 |
新型cas13b直向同源物crispr酶和系统
|
EP3601562A1
(en)
|
2017-03-23 |
2020-02-05 |
President and Fellows of Harvard College |
Nucleobase editors comprising nucleic acid programmable dna binding proteins
|
CA3059757A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Novel type vi crispr orthologs and systems
|
SG11201911256UA
(en)
|
2017-05-08 |
2020-01-30 |
Orgenesis Ltd |
Transdifferentiated cell populations and methods of use thereof
|
WO2018208910A1
(en)
|
2017-05-09 |
2018-11-15 |
The Broad Institute Inc. |
Gut microbiome function predicts response to anti-integrin biologic therapy in inflammatory bowel diseases
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
US11820822B2
(en)
|
2017-06-06 |
2023-11-21 |
Dana-Farber Cancer Institute, Inc. |
Methods for sensitizing cancer cells to T cell-mediated killing by modulating molecular pathways
|
US20210093667A1
(en)
|
2017-06-26 |
2021-04-01 |
The Broad Institute, Inc. |
Crispr/cas-adenine deaminase based compositions, systems, and methods for targeted nucleic acid editing
|
WO2019023680A1
(en)
|
2017-07-28 |
2019-01-31 |
President And Fellows Of Harvard College |
METHODS AND COMPOSITIONS FOR EVOLUTION OF BASIC EDITORS USING PHAGE-ASSISTED CONTINUOUS EVOLUTION (PACE)
|
EP3676376B1
(en)
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
High efficiency base editors comprising gam
|
WO2019060746A1
(en)
|
2017-09-21 |
2019-03-28 |
The Broad Institute, Inc. |
SYSTEMS, METHODS, AND COMPOSITIONS FOR THE TARGETED EDITING OF NUCLEIC ACIDS
|
EP3466975A1
(en)
|
2017-10-05 |
2019-04-10 |
Laboratoire Français du Fractionnement et des Biotechnologies |
A specific binding molecule directed against galectin-3 protein
|
EP3697906A1
(en)
|
2017-10-16 |
2020-08-26 |
The Broad Institute, Inc. |
Uses of adenosine base editors
|
WO2019089803A1
(en)
|
2017-10-31 |
2019-05-09 |
The Broad Institute, Inc. |
Methods and compositions for studying cell evolution
|
CN111655230A
(zh)
|
2017-11-07 |
2020-09-11 |
拉尼医疗有限公司 |
使用可吞服药物递送装置递送到肠道组织中的凝血因子制剂
|
US11591385B2
(en)
|
2017-11-09 |
2023-02-28 |
Pinteon Therapeutics Inc. |
Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
|
WO2019094983A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
WO2019094984A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells
|
EP3488858A1
(en)
|
2017-11-27 |
2019-05-29 |
Laboratoire Français du Fractionnement et des Biotechnologies |
A von willebrand factor composition for use in treating a pathology mediated by angiogenesis
|
FR3075200B1
(fr)
|
2017-12-15 |
2022-12-23 |
Lab Francais Du Fractionnement |
Variants avec fragment fc ayant une affinite augmentee pour fcrn et une affinite augmentee pour au moins un recepteur du fragment fc
|
FR3075603A1
(fr)
|
2017-12-21 |
2019-06-28 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Composition pharmaceutique pour administration orale d'anticorps pour le traitement des maladies du tractus gastro-intestinal
|
CR20200450A
(es)
|
2018-04-02 |
2021-02-11 |
Bristol Myers Squibb Co |
Anticuerpos anti-trem-l y usos de los mismos
|
US10968257B2
(en)
|
2018-04-03 |
2021-04-06 |
The Broad Institute, Inc. |
Target recognition motifs and uses thereof
|
WO2019209807A1
(en)
|
2018-04-23 |
2019-10-31 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Compositions and methods for modulating endoplasmic reticulum-associated degradation
|
WO2019211842A1
(en)
|
2018-04-30 |
2019-11-07 |
Opko Biologics Ltd. |
Long-acting human growth hormone-antagonists and methods of producing the same
|
EP3797160A1
(en)
|
2018-05-23 |
2021-03-31 |
The Broad Institute Inc. |
Base editors and uses thereof
|
EP3581203A1
(en)
|
2018-06-11 |
2019-12-18 |
Laboratoire Français du Fractionnement et des Biotechnologies |
Antibodies with increased activity in the digestive tract
|
WO2019244107A1
(en)
|
2018-06-21 |
2019-12-26 |
Daiichi Sankyo Company, Limited |
Compositions including cd3 antigen binding fragments and uses thereof
|
US11873322B2
(en)
|
2018-06-25 |
2024-01-16 |
Yeda Research And Development Co. Ltd. |
Systems and methods for increasing efficiency of genome editing
|
CA3104780A1
(en)
|
2018-07-11 |
2020-01-16 |
Kahr Medical Ltd. |
Sirpalpha-4-1bbl variant fusion protein and methods of use thereof
|
AU2019318079A1
(en)
|
2018-08-07 |
2021-01-28 |
Massachusetts Institute Of Technology |
Novel Cas12b enzymes and systems
|
WO2020041380A1
(en)
|
2018-08-20 |
2020-02-27 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of crispr-cas9
|
WO2020086627A1
(en)
|
2018-10-22 |
2020-04-30 |
University Of Rochester |
Genome editing by directed non-homologous dna insertion using a retroviral integrase-cas9 fusion protein
|
CN113286816A
(zh)
|
2018-10-29 |
2021-08-20 |
斯宾疗法有限责任公司 |
用于α-1-抗胰蛋白酶病症的组合物和方法
|
US20220282275A1
(en)
|
2018-11-15 |
2022-09-08 |
The Broad Institute, Inc. |
G-to-t base editors and uses thereof
|
MX2021008487A
(es)
|
2019-01-14 |
2021-11-12 |
Univ Rochester |
Escisión y poliadenilación del arn nuclear dirigido con crispr-cas.
|
US12215382B2
(en)
|
2019-03-01 |
2025-02-04 |
The General Hospital Corporation |
Liver protective MARC variants and uses thereof
|
WO2020181180A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
A:t to c:g base editors and uses thereof
|
WO2020181202A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
A:t to t:a base editing through adenine deamination and oxidation
|
WO2020181178A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through thymine alkylation
|
WO2020181195A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenine excision
|
WO2020181193A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenosine methylation
|
EP3938400A4
(en)
|
2019-03-11 |
2022-11-23 |
Memorial Sloan Kettering Cancer Center |
Cd22 antibodies and methods of using the same
|
GB201903520D0
(en)
|
2019-03-14 |
2019-05-01 |
Tropic Biosciences Uk Ltd |
Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells
|
GB201903519D0
(en)
|
2019-03-14 |
2019-05-01 |
Tropic Biosciences Uk Ltd |
Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest
|
WO2020191102A1
(en)
|
2019-03-18 |
2020-09-24 |
The Broad Institute, Inc. |
Type vii crispr proteins and systems
|
IL265486A
(en)
|
2019-03-19 |
2020-09-30 |
Yeda Res & Dev |
Bistable type ii opsins and uses thereof
|
EP3942042A1
(en)
|
2019-03-19 |
2022-01-26 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
US20220192992A1
(en)
|
2019-04-01 |
2022-06-23 |
Vta Labs, Llc |
Protection of monoclonal antibody integrity against evaporative solidification, compression and proteolysis by dextran and cyclodextrin derivatives
|
US20220307003A1
(en)
|
2019-04-17 |
2022-09-29 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
EP3962529A4
(en)
|
2019-04-30 |
2023-11-01 |
Dana-Farber Cancer Institute, Inc. |
METHOD FOR CANCER TREATMENT USING ANTI-CX3CR1 AND IMMUNE CHECKPOINT BLOCKING REAGENTS COMBINATIONS
|
AU2020270420A1
(en)
|
2019-05-03 |
2021-11-18 |
Rani Therapeutics, Llc |
Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device
|
WO2020236972A2
(en)
|
2019-05-20 |
2020-11-26 |
The Broad Institute, Inc. |
Non-class i multi-component nucleic acid targeting systems
|
WO2020243393A1
(en)
|
2019-05-30 |
2020-12-03 |
Vta Labs, Llc |
Design of a single oral delivery system containing a monoclonal antibody for the simultaneous treatment of chron's disease and ulcerative colitis
|
US20210008172A1
(en)
|
2019-07-11 |
2021-01-14 |
Opko Biologics Ltd. |
Long-acting igf-1 or igf-1 variants and methods of producing same
|
MX2022000367A
(es)
|
2019-07-11 |
2022-07-13 |
Kahr Medical Ltd |
Heterodimeros, metodos y uso de los mismos.
|
WO2021016453A1
(en)
|
2019-07-23 |
2021-01-28 |
University Of Rochester |
Targeted rna cleavage with crispr-cas
|
WO2021030666A1
(en)
|
2019-08-15 |
2021-02-18 |
The Broad Institute, Inc. |
Base editing by transglycosylation
|
CN114729384A
(zh)
|
2019-09-12 |
2022-07-08 |
博德研究所 |
工程化腺相关病毒衣壳
|
EP4058477A2
(en)
|
2019-11-11 |
2022-09-21 |
IBI-AG Innovative Bio Insecticides Ltd. |
Insect control nanobodies and uses thereof
|
WO2021108717A2
(en)
|
2019-11-26 |
2021-06-03 |
The Broad Institute, Inc |
Systems and methods for evaluating cas9-independent off-target editing of nucleic acids
|
IL271656A
(en)
|
2019-12-22 |
2021-06-30 |
Yeda Res & Dev |
System and methods for identifying cells that have undergone genome editing
|
WO2021150925A1
(en)
|
2020-01-24 |
2021-07-29 |
Dana-Farber Cancer Institute, Inc. |
Uses of biomarkers for improving immunotherapy
|
EP4100519A2
(en)
|
2020-02-05 |
2022-12-14 |
The Broad Institute, Inc. |
Adenine base editors and uses thereof
|
US20230103771A1
(en)
|
2020-03-27 |
2023-04-06 |
University Of Rochester |
CRISPR-Cas13 crRNA Arrays
|
US20240218367A1
(en)
|
2020-03-27 |
2024-07-04 |
University Of Rochester |
Targeted Destruction of Viral RNA by CRISPR-Cas13
|
CN116096873A
(zh)
|
2020-05-08 |
2023-05-09 |
布罗德研究所股份有限公司 |
同时编辑靶标双链核苷酸序列的两条链的方法和组合物
|
CA3185589A1
(en)
|
2020-07-15 |
2022-01-20 |
Douglas Matthew ANDERSON |
Targeted rna cleavage with dcasl3-rnase fusion proteins
|
EP4182458A2
(en)
|
2020-07-20 |
2023-05-24 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for treatment and prevention of coronavirus infection
|
US20230304047A1
(en)
|
2020-08-11 |
2023-09-28 |
University Of Oslo |
Improved gene editing
|
US12006550B2
(en)
|
2020-10-12 |
2024-06-11 |
University Of South Carolina |
Targeting treatment for ADAM30 in pathological cells
|
IL278401A
(en)
|
2020-10-29 |
2022-05-01 |
Yeda Res & Dev |
Polynucleotides for editing RNA and a method for using them
|
CN117425501A
(zh)
|
2021-01-13 |
2024-01-19 |
纪念斯隆凯特琳癌症中心 |
抗体-吡咯并苯二氮䓬衍生物缀合物
|
CN117425500A
(zh)
|
2021-01-13 |
2024-01-19 |
纪念斯隆凯特琳癌症中心 |
抗dll3抗体-药物缀合物
|
EP4326753A2
(en)
|
2021-04-23 |
2024-02-28 |
University of Rochester |
Genome editing by directed non-homologous dna insertion using a retroviral integrase-cas fusion protein and methods of treatment
|
US20240280561A1
(en)
|
2021-06-08 |
2024-08-22 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating and/or identifying an agent for treating intestinal cancers
|
US20240325568A1
(en)
|
2021-07-20 |
2024-10-03 |
The Broad Institute, Inc. |
Engineered targeting compositions for endothelial cells of the central nervous system vasculature and methods of use thereof
|
WO2023097119A2
(en)
|
2021-11-29 |
2023-06-01 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions to modulate riok2
|
WO2023196802A1
(en)
|
2022-04-04 |
2023-10-12 |
The Broad Institute, Inc. |
Cas9 variants having non-canonical pam specificities and uses thereof
|
WO2023240137A1
(en)
|
2022-06-08 |
2023-12-14 |
The Board Institute, Inc. |
Evolved cas14a1 variants, compositions, and methods of making and using same in genome editing
|
TW202428311A
(zh)
|
2022-07-14 |
2024-07-16 |
美商博得學院股份有限公司 |
藉由與運鐵蛋白受體的相互作用實現cns範圍之基因傳遞的aav衣殼
|
WO2024040083A1
(en)
|
2022-08-16 |
2024-02-22 |
The Broad Institute, Inc. |
Evolved cytosine deaminases and methods of editing dna using same
|
WO2024081245A1
(en)
|
2022-10-10 |
2024-04-18 |
Therapeutics By Design, LLC |
Tissue differentiation factor related polypeptides (tdfrps) for the treatment of myocardial injury
|
WO2024155745A1
(en)
|
2023-01-18 |
2024-07-25 |
The Broad Institute, Inc. |
Base editing-mediated readthrough of premature termination codons (bert)
|
WO2024163842A2
(en)
|
2023-02-03 |
2024-08-08 |
The Broad Institute, Inc. |
Delivering genes to the brain endothelium to treat lysosomal storage disorder-derived neuropathology
|
WO2025011876A2
(en)
|
2023-07-08 |
2025-01-16 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts |
Antisense long noncoding rnas for the modification of gene expression and for therapeutic applications
|