NL192206C - Werkwijze voor het bereiden van een 13ß-alkyl-17Ó-ethynyl-17ß- alkanoyloxy-gon-4-en-3-on-oxim verbinding, werkwijze voor het bereiden van farmaceutische preparaten met een dergelijke verbinding alsmede de gevormde farmaceutische preparaten. - Google Patents

Werkwijze voor het bereiden van een 13ß-alkyl-17Ó-ethynyl-17ß- alkanoyloxy-gon-4-en-3-on-oxim verbinding, werkwijze voor het bereiden van farmaceutische preparaten met een dergelijke verbinding alsmede de gevormde farmaceutische preparaten. Download PDF

Info

Publication number: NL192206C
Authority: NL; Netherlands
Prior art keywords: compound; ethynyl; gon; preparation; ethyl
Prior art date: 1975-07-24

Application number

NL7608210A

Other languages

English (en)

Dutch (nl)

Other versions

NL192206B (nl

NL7608210A (nl

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-07-24

Filing date

1976-07-23

Publication date

1997-03-04

1976-07-23 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1977-01-26 Publication of NL7608210A publication Critical patent/NL7608210A/xx

1996-11-01 Publication of NL192206B publication Critical patent/NL192206B/xx

1997-03-04 Application granted granted Critical

1997-03-04 Publication of NL192206C publication Critical patent/NL192206C/nl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Reproductive Health (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Fertilizers (AREA)

NL7608210A 1975-07-24 1976-07-23 Werkwijze voor het bereiden van een 13ß-alkyl-17Ó-ethynyl-17ß- alkanoyloxy-gon-4-en-3-on-oxim verbinding, werkwijze voor het bereiden van farmaceutische preparaten met een dergelijke verbinding alsmede de gevormde farmaceutische preparaten. NL192206C (nl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US59896675A	1975-07-24	1975-07-24
US59896675		1975-07-24
US05/652,000 US4027019A (en)	1975-07-24	1976-01-23	3-Oximes of D-17α-ethynyl-19-nortestosterone esters and method
US65200076		1976-01-23

Publications (3)

Publication Number	Publication Date
NL7608210A NL7608210A (nl)	1977-01-26
NL192206B NL192206B (nl)	1996-11-01
NL192206C true NL192206C (nl)	1997-03-04

Family

ID=27083202

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL7608210A NL192206C (nl)	1975-07-24	1976-07-23	Werkwijze voor het bereiden van een 13ß-alkyl-17Ó-ethynyl-17ß- alkanoyloxy-gon-4-en-3-on-oxim verbinding, werkwijze voor het bereiden van farmaceutische preparaten met een dergelijke verbinding alsmede de gevormde farmaceutische preparaten.

Country Status (22)

Country	Link
US (1)	US4027019A (da)
JP (1)	JPS5214760A (da)
AT (1)	AT350748B (da)
AU (1)	AU501808B2 (da)
CA (1)	CA1072948A (da)
CH (1)	CH599249A5 (da)
DE (2)	DE2633210C2 (da)
DK (1)	DK145610C (da)
ES (1)	ES450108A1 (da)
FI (1)	FI55036C (da)
FR (1)	FR2318645A1 (da)
GB (1)	GB1557197A (da)
IE (1)	IE43581B1 (da)
IL (1)	IL50103A (da)
MX (1)	MX3417E (da)
NL (1)	NL192206C (da)
NO (1)	NO143350C (da)
NZ (1)	NZ181130A (da)
PH (1)	PH12003A (da)
PT (1)	PT65402B (da)
SE (2)	SE421800B (da)
YU (1)	YU39968B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4507290A (en) *	1981-04-07	1985-03-26	World Health Organization	Esters of 17 α-ethynyl 19-nor-testosterone and 17 α-ethynyl-18-homo-19-nor-testosterone and pharmaceutical compositions containing the same
GB8313921D0 (en) *	1983-05-19	1983-06-22	World Health Org	Contraceptive compositions
WO1993013122A1 (de) *	1991-12-22	1993-07-08	Schering Aktiengesellschaft	3-methylsulfonylhydrazono- und 3-oxyimino-steroide, ein verfahren zu deren herstellung, diese steroide enthaltende pharmazeutische präparate sowie ihre verwendung zur herstellung von arzneimitteln
US7459445B2 (en) *	2000-03-10	2008-12-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and topical pharmaceutical formulations of the same
US6855703B1 (en)	2000-03-10	2005-02-15	Endeavor Pharmaceuticals	Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7989436B2 (en)	2003-07-23	2011-08-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and pharmaceutical formulations comprising the same
US6660726B2 (en)	2000-03-10	2003-12-09	Endeavor Pharmaceuticals	Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
EP1363669A2 (en) *	2001-02-02	2003-11-26	Pharmacia Corporation	Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
US6992075B2 (en) *	2003-04-04	2006-01-31	Barr Laboratories, Inc.	C(14) estrogenic compounds
JP2006522833A (ja) *	2003-04-11	2006-10-05	バー・ラボラトリーズ，インコーポレイテッド	エストロゲンおよびプロゲスチンの投与法
AR039733A1 (es) *	2003-06-25	2005-03-09	Gador Sa	Proceso para la obtencion de norelgestromin en distintas relaciones de los isomeros e y z
HUP0301981A2 (hu) *	2003-06-30	2005-04-28	Richter Gedeon Vegyészeti Gyár Rt.	Tiszta d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-3E- és 3Z-oxim izomerek, valamint eljárás az izomer keverékek és a tiszta izomerek előállítására
US7816546B2 (en) *	2003-06-30	2010-10-19	Richter Gedeon Vegyeszeti Gyar Rt.	Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime
HUP0301982A2 (hu) *	2003-06-30	2005-04-28	Richter Gedeon Vegyészeti Gyár Rt.	Eljárás nagy tisztaságú d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-oxim előállítására
CA2575138A1 (en) *	2004-08-12	2006-02-23	Sicor, Inc.	Process for the preparation of 3-oximino steroids
US20060183724A1 (en) *	2005-02-03	2006-08-17	Diliberti Charles E	Compositions of unconjugated estrogens and methods for their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1493161B2 (de) *	1951-01-28	1973-08-30		17alpha-aethinyl-18-methyl-19nortestosteronester, verfahren zu ihrer herstellung und diese enthaltendes mittel
US3780073A (en) *	1966-07-06	1973-12-18	Ortho Pharma Corp	3-oximes of 19-nortestosterone esters
US3532689A (en) *	1967-04-20	1970-10-06	Ortho Pharma Corp	3-oxime and 3-oxime esters of 19-nortestosterone
NL7306609A (da) *	1972-05-26	1973-11-28
US3912768A (en) *	1972-09-26	1975-10-14	Warner Lambert Co	Norethindrone O-alkyloximes

1976
- 1976-01-23 US US05/652,000 patent/US4027019A/en not_active Expired - Lifetime
- 1976-06-11 NZ NZ181130A patent/NZ181130A/en unknown
- 1976-06-14 FR FR7617973A patent/FR2318645A1/fr active Granted
- 1976-06-14 PH PH18572A patent/PH12003A/en unknown
- 1976-06-15 GB GB24769/76A patent/GB1557197A/en not_active Expired
- 1976-06-28 AU AU15357/76A patent/AU501808B2/en not_active Expired
- 1976-07-06 CA CA256,343A patent/CA1072948A/en not_active Expired
- 1976-07-13 YU YU1733/76A patent/YU39968B/xx unknown
- 1976-07-22 MX MX001792U patent/MX3417E/es unknown
- 1976-07-22 JP JP51086661A patent/JPS5214760A/ja active Granted
- 1976-07-22 CH CH940376A patent/CH599249A5/xx not_active IP Right Cessation
- 1976-07-22 IL IL50103A patent/IL50103A/xx unknown
- 1976-07-23 FI FI762116A patent/FI55036C/fi not_active IP Right Cessation
- 1976-07-23 NO NO762583A patent/NO143350C/no unknown
- 1976-07-23 IE IE1636/76A patent/IE43581B1/en unknown
- 1976-07-23 DE DE2633210A patent/DE2633210C2/de not_active Expired
- 1976-07-23 NL NL7608210A patent/NL192206C/nl not_active IP Right Cessation
- 1976-07-23 ES ES450108A patent/ES450108A1/es not_active Expired
- 1976-07-23 AT AT543976A patent/AT350748B/de not_active IP Right Cessation
- 1976-07-23 DK DK335876A patent/DK145610C/da not_active IP Right Cessation
- 1976-07-23 SE SE7608407A patent/SE421800B/xx not_active IP Right Cessation
- 1976-07-23 PT PT65402A patent/PT65402B/pt unknown
- 1976-07-23 DE DE2661002A patent/DE2661002C2/de not_active Expired
1979
- 1979-12-14 SE SE7910336A patent/SE445458B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPS624400B2 (da)	1987-01-30
FR2318645B1 (da)	1978-11-17
PT65402A (en)	1976-08-01
SE421800B (sv)	1982-02-01
AU1535776A (en)	1978-01-05
ATA543976A (de)	1978-11-15
YU39968B (en)	1985-06-30
DE2661002C2 (da)	1988-03-17
DE2661002A1 (da)	1985-05-02
NO143350C (no)	1981-01-28
IL50103A0 (en)	1976-09-30
NL192206B (nl)	1996-11-01
AU501808B2 (en)	1979-06-28
US4027019A (en)	1977-05-31
FI762116A (da)	1977-01-25
DK335876A (da)	1977-01-25
NO143350B (no)	1980-10-13
DK145610B (da)	1982-12-27
YU173376A (en)	1982-08-31
JPS5214760A (en)	1977-02-03
FR2318645A1 (fr)	1977-02-18
DE2633210A1 (de)	1977-02-17
IL50103A (en)	1979-11-30
ES450108A1 (es)	1977-11-16
CH599249A5 (da)	1978-05-31
SE7910336L (sv)	1979-12-14
NO762583L (da)	1977-01-25
PH12003A (en)	1978-10-06
AT350748B (de)	1979-06-11
SE445458B (sv)	1986-06-23
FI55036B (fi)	1979-01-31
NZ181130A (en)	1984-07-06
IE43581L (en)	1977-01-24
SE7608407L (sv)	1977-01-25
NL7608210A (nl)	1977-01-26
CA1072948A (en)	1980-03-04
FI55036C (fi)	1979-05-10
MX3417E (es)	1980-11-13
DK145610C (da)	1983-08-01
IE43581B1 (en)	1981-04-08
DE2633210C2 (de)	1987-04-09
PT65402B (en)	1979-06-09
GB1557197A (en)	1979-12-05

Publication	Publication Date	Title
NL192206C (nl)	1997-03-04	Werkwijze voor het bereiden van een 13ß-alkyl-17Ó-ethynyl-17ß- alkanoyloxy-gon-4-en-3-on-oxim verbinding, werkwijze voor het bereiden van farmaceutische preparaten met een dergelijke verbinding alsmede de gevormde farmaceutische preparaten.
US4738957A (en)	1988-04-19	Estriol esters
EP1272504B1 (de)	2007-05-30	8.beta.-hydrocarbyl-substituierte estratriene als selektiv wirksame estrogene
Rapala et al.	1965	The adamantyl group in medicinal agents. II. Anabolic steroid 17β-adamantoates
IL105684A (en)	1998-08-16	History of A. Nedersten 3-On, pharmaceutical preparations containing them
SK79298A3 (en)	2000-06-12	Contraceptive process and kit for female mammals, comprising a combination of gestagen and oestrogen
IL90410A (en)	1994-07-31	A medicinal product containing estrogen and pure antiestrogen and medicinal preparations containing the product
NO316518B1 (no)	2004-02-02	Testosteron-derivat
US3159543A (en)	1964-12-01	3-cyclopentyl and cyclopentenyl ethers of estrone and derivatives thereof
NO145198B (no)	1981-10-26	Analogifremgangsmaate til fremstilling av terapeutisk aktivt 1,2-benzisotia-zolinon-3
CZ290690B6 (cs)	2002-09-11	Léčivo pro podle potřeby zaměřenou kontrolu samičí fertility
EP0318490B1 (de)	1992-01-29	14,17-g(b)-ETHANO-14-g(b)-ESTRATRIENE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMAZEUTISCHE PRÄPARATE
EP1517914B1 (de)	2005-08-31	9-alpha-substituierte estratriene als selektiv wirksame estrogene
Drill	1977	History of the first oral contraceptive
GB1604664A (en)	1981-12-16	Pharmaceutical composition and absortion method for non-human mammals
Suchowsky et al.	1964	Relationship between progestational activity and chemical structure of synthetic steroids
KR20010041698A (ko)	2001-05-25	신규 피임 키트
MXPA04011798A (es)	2005-03-31	Uso de nuevos esteres de etonogestrel.
Banik et al.	1969	Orally active oestrogens and progestins in prevention of pregnancy in rats
JP3754466B2 (ja)	2006-03-15	ジエノゲストを有効成分とするホルモン療法用制癌剤
US3916001A (en)	1975-10-28	15{60 ,16{60 ,-Methylene-10-nor-18-methyl-4-pregnenes
US3966926A (en)	1976-06-29	Composition of a steroidal[2,3-d]-isoxazole and method of use thereof
US3370071A (en)	1968-02-20	3-keto-13beta-alkyl-17beta-acetyl-gona-4, 9-dienes and process
US3816406A (en)	1974-06-11	O-aryl oximes of 3-keto steroids
KR840000120B1 (ko)	1984-02-16	7α-메틸놀에틴드론 에난세이트의 제조방법

Legal Events

Date	Code	Title	Description
1983-07-01	BA	A request for search or an international-type search has been filed
1983-11-01	BB	A search report has been drawn up
1984-03-01	BC	A request for examination has been filed
1985-01-01	A85	Still pending on 85-01-01
1997-05-01	V4	Discontinued because of reaching the maximum lifetime of a patent	Free format text: 970304