MXPA05003891A - Medicina que comprende una tiourea para utilizarse como un agente despigmentante o un agente antimutagenico y anticarcinogenico. - Google Patents
Medicina que comprende una tiourea para utilizarse como un agente despigmentante o un agente antimutagenico y anticarcinogenico.Info
- Publication number
- MXPA05003891A MXPA05003891A MXPA05003891A MXPA05003891A MXPA05003891A MX PA05003891 A MXPA05003891 A MX PA05003891A MX PA05003891 A MXPA05003891 A MX PA05003891A MX PA05003891 A MXPA05003891 A MX PA05003891A MX PA05003891 A MXPA05003891 A MX PA05003891A
- Authority
- MX
- Mexico
- Prior art keywords
- medicine
- agent
- thiourea
- mutagenic
- depigmenting
- Prior art date
Links
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title abstract 2
- 230000002790 anti-mutagenic effect Effects 0.000 title abstract 2
- 239000003005 anticarcinogenic agent Substances 0.000 title abstract 2
- 239000002592 antimutagenic agent Substances 0.000 title abstract 2
- 239000007854 depigmenting agent Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 102000003425 Tyrosinase Human genes 0.000 abstract 1
- 108060008724 Tyrosinase Proteins 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 230000008099 melanin synthesis Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invencion se refiere a un medicamento o una composicion cosmetica que comprende al menos una tiourea de formula general I, o al menos uno de sus derivados de monoxido o dioxido de formulas generales (IIa), (IIb) y (III), o mezclas de los mismos; ventajosamente, este medicamento es utilizado para inhibir la tirosinasa, inhibir la sintesis de la melamina, aclarar o despigmentar la epidermis o eliminar las manchas ocasionadas por la edad y como agente anti-mutagenico y anti-carcinogenico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0212697A FR2845599B1 (fr) | 2002-10-11 | 2002-10-11 | Medicament comprenant une thiouree pour son utilisation en tant que depigmentant |
PCT/FR2003/002907 WO2004032912A1 (fr) | 2002-10-11 | 2003-10-03 | Medicament comprenant une thiouree pour son utilisation en tant que depigmentant ou agent antimutagene et anticarcinogene |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05003891A true MXPA05003891A (es) | 2005-08-03 |
Family
ID=32039668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05003891A MXPA05003891A (es) | 2002-10-11 | 2003-10-03 | Medicina que comprende una tiourea para utilizarse como un agente despigmentante o un agente antimutagenico y anticarcinogenico. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20060135618A1 (es) |
EP (1) | EP1553933B1 (es) |
JP (1) | JP2006509733A (es) |
KR (1) | KR20050094806A (es) |
AT (1) | ATE367807T1 (es) |
AU (1) | AU2003286213A1 (es) |
CA (1) | CA2501742A1 (es) |
DE (1) | DE60315176D1 (es) |
FR (1) | FR2845599B1 (es) |
MX (1) | MXPA05003891A (es) |
NO (1) | NO20052176L (es) |
WO (1) | WO2004032912A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2881654B1 (fr) * | 2005-02-07 | 2009-05-29 | Lmd | Compositions medicinales contenant une alkylsulfone pour le traitement du cancer en association a des agents chimiotherapeutiques ou a des rayonnements ionisants ou non ionisants |
FR2890070A1 (fr) * | 2005-08-31 | 2007-03-02 | Galderma Res & Dev | Nouveaux inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
WO2007039821A2 (en) * | 2005-08-31 | 2007-04-12 | Galderma Research & Development | Novel inhibitors of tyrosinase, their method of preparation and their use in human medicine and in cosmetics |
WO2008015315A1 (fr) * | 2006-08-03 | 2008-02-07 | Lmd | Compositions medicinales contenant une thiouree pour le traitement du cancer en association avec des agents chimiotherapeutiques ou des rayonnements ionisants ou non ionisants |
BRPI1009037A2 (pt) * | 2009-06-09 | 2017-06-06 | Mardi Medicines Ltd | ''ácidos carboxílicos halogenados alifáticos, oligômeros, e/ou respectivos polímeros e seu uso na desvitalização de neoplamas externos e internos'' |
BE1019432A3 (fr) * | 2010-07-23 | 2012-07-03 | Auriga Internat | Utilisation d'isothiocyanates et derives pour le traitement et/ou la prevention des lucites. |
BE1019431A3 (fr) * | 2010-07-23 | 2012-07-03 | Auriga Internat | Procede de synthese d'isothiocyanates et leurs derives et utilisations de ceux-ci. |
AU2013269340B9 (en) | 2012-06-01 | 2017-08-17 | Pharmagra Labs, Inc. | Method of synthesising sulforaphane |
TWI508950B (zh) * | 2014-08-29 | 2015-11-21 | Univ Hungkuang | 3-methyl-2-sulfanyl-2,3-dihydro-1H-imidazole-1-carboxylic acid Tertiary butyl ester and its preparation method and use |
CN109661224B (zh) | 2016-09-06 | 2022-05-24 | 联合利华知识产权控股有限公司 | 用于降低细胞黑色素含量的化合物 |
KR102201385B1 (ko) * | 2018-10-11 | 2021-01-11 | 주식회사 그라젬 | 피부 미백용 조성물 및 이를 이용한 미백용 화장품 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5411986A (en) * | 1993-03-12 | 1995-05-02 | The Johns Hopkins University | Chemoprotective isothiocyanates |
ES2352974T3 (es) * | 2000-02-29 | 2011-02-24 | Mediquest Therapeutics, Inc. | Inhibidores de tirosinasa de melanocitos como aclaradores tópicos de la piel. |
FR2820036B1 (fr) * | 2001-01-26 | 2005-12-09 | L M D | Utilisation d'un isothiocyanate, d'un thiocyanate ou de leur melange en tant que depigmentant |
-
2002
- 2002-10-11 FR FR0212697A patent/FR2845599B1/fr not_active Expired - Fee Related
-
2003
- 2003-10-03 MX MXPA05003891A patent/MXPA05003891A/es unknown
- 2003-10-03 JP JP2004542546A patent/JP2006509733A/ja not_active Withdrawn
- 2003-10-03 AT AT03776954T patent/ATE367807T1/de not_active IP Right Cessation
- 2003-10-03 DE DE60315176T patent/DE60315176D1/de not_active Expired - Lifetime
- 2003-10-03 AU AU2003286213A patent/AU2003286213A1/en not_active Abandoned
- 2003-10-03 US US10/530,723 patent/US20060135618A1/en not_active Abandoned
- 2003-10-03 KR KR1020057006214A patent/KR20050094806A/ko not_active Withdrawn
- 2003-10-03 CA CA002501742A patent/CA2501742A1/fr not_active Abandoned
- 2003-10-03 EP EP03776954A patent/EP1553933B1/fr not_active Expired - Lifetime
- 2003-10-03 WO PCT/FR2003/002907 patent/WO2004032912A1/fr active IP Right Grant
-
2005
- 2005-05-03 NO NO20052176A patent/NO20052176L/no unknown
Also Published As
Publication number | Publication date |
---|---|
JP2006509733A (ja) | 2006-03-23 |
ATE367807T1 (de) | 2007-08-15 |
DE60315176D1 (de) | 2007-09-06 |
AU2003286213A1 (en) | 2004-05-04 |
WO2004032912A1 (fr) | 2004-04-22 |
KR20050094806A (ko) | 2005-09-28 |
NO20052176L (no) | 2005-05-03 |
FR2845599A1 (fr) | 2004-04-16 |
EP1553933B1 (fr) | 2007-07-25 |
US20060135618A1 (en) | 2006-06-22 |
EP1553933A1 (fr) | 2005-07-20 |
CA2501742A1 (fr) | 2004-04-22 |
FR2845599B1 (fr) | 2005-01-07 |
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