MXPA02010091A - Novedoso uso medico de inhibidores de sintasa de aldosterona solos o en combinacion con antagonistas del receptor at-1. - Google Patents

Novedoso uso medico de inhibidores de sintasa de aldosterona solos o en combinacion con antagonistas del receptor at-1.

Info

Publication number: MXPA02010091A
Authority: MX; Mexico
Prior art keywords: hypertension; pharmaceutically acceptable; acceptable salt; renal failure; restenosis
Prior art date: 2000-04-12

Application number

MXPA02010091A

Other languages

English (en)

Spanish (es)

Inventor

Ronald Edward Steele

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-12

Filing date

2001-04-10

Publication date

2003-02-12

2001-04-10 Application filed by Novartis Ag filed Critical Novartis Ag

2003-02-12 Publication of MXPA02010091A publication Critical patent/MXPA02010091A/es

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
- A—HUMAN NECESSITIES
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Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Heart & Thoracic Surgery (AREA)
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MXPA02010091A 2000-04-12 2001-04-10 Novedoso uso medico de inhibidores de sintasa de aldosterona solos o en combinacion con antagonistas del receptor at-1. MXPA02010091A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19674200P	2000-04-12	2000-04-12
PCT/EP2001/004116 WO2001076574A2 (en)	2000-04-12	2001-04-10	Novel medical use of aldosterone synthase inhibitors alone or in combination with at1-receptor antagonists

Publications (1)

Publication Number	Publication Date
MXPA02010091A true MXPA02010091A (es)	2003-02-12

Family

ID=22726655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MXPA02010091A MXPA02010091A (es)	2000-04-12	2001-04-10	Novedoso uso medico de inhibidores de sintasa de aldosterona solos o en combinacion con antagonistas del receptor at-1.

Country Status (19)

Country	Link
EP (1)	EP1282410A2 (zh)
JP (1)	JP2003530343A (zh)
KR (1)	KR20020089437A (zh)
CN (1)	CN1422152A (zh)
AR (1)	AR032316A1 (zh)
AU (2)	AU7393801A (zh)
BR (1)	BR0110079A (zh)
CA (1)	CA2405895A1 (zh)
HU (1)	HUP0301335A3 (zh)
IL (1)	IL152081A0 (zh)
MX (1)	MXPA02010091A (zh)
NO (1)	NO20024920L (zh)
NZ (1)	NZ521855A (zh)
PE (1)	PE20020082A1 (zh)
PL (1)	PL358459A1 (zh)
RU (1)	RU2002129569A (zh)
SK (1)	SK14612002A3 (zh)
WO (1)	WO2001076574A2 (zh)
ZA (1)	ZA200208204B (zh)

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ITTO20040760A1 (it) *	2004-11-03	2005-02-03	Uni Degli Studi Del Piemonte	Uso di un corticosteroide in associazione ad altri principi attivi per il trattamento della stenosi vascolare e la prevenzione della restenosi vascolare
EP1674080A1 (en) *	2004-12-24	2006-06-28	KRKA, D.D., Novo Mesto	Solid pharmaceutical composition comprising valsartan
EA012392B1 (ru) *	2004-12-24	2009-10-30	Крка, Д.Д. Ново Место	Твердая фармацевтическая композиция, содержащая валсартан
US9271963B2 (en)	2005-03-03	2016-03-01	Universitat Des Saarlandes	Selective inhibitors of human corticosteroid synthases
TW200716636A (en)	2005-05-31	2007-05-01	Speedel Experimenta Ag	Heterocyclic spiro-compounds
GT200600381A (es)	2005-08-25	2007-03-28		Compuestos organicos
EP1842543A1 (en)	2006-04-05	2007-10-10	Speedel Pharma AG	Pharmaceutical composition coprising an aldosterone synthase inhibitor and a mineralcorticoid receptor antagonist
TW200808813A (en) *	2006-04-12	2008-02-16	Speedel Experimenta Ag	Imidazo compounds
TW200808812A (en) *	2006-04-12	2008-02-16	Speedel Experimenta Ag	Imidazo compounds
EP2095819A1 (en)	2008-02-28	2009-09-02	Maastricht University	N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors
KR20120041702A (ko)	2009-05-28	2012-05-02	노파르티스 아게	네프릴리신 억제제로서의 치환된 아미노부티르산 유도체
BRPI1011657A2 (pt)	2009-05-28	2019-04-16	Novartis Ag	derivados aminopropiônicos substituídos como inibidores de neprilisina
JO2967B1 (en)	2009-11-20	2016-03-15	نوفارتس ايه جي	Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
US8673974B2 (en)	2010-11-16	2014-03-18	Novartis Ag	Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
US8877815B2 (en)	2010-11-16	2014-11-04	Novartis Ag	Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
KR20190025737A (ko)	2011-07-08	2019-03-11	노파르티스 아게	높은 트리글리세리드 대상체에서의 아테롬성동맥경화증의 치료 방법
UY35144A (es)	2012-11-20	2014-06-30	Novartis Ag	Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
MA38330B1 (fr)	2013-02-14	2016-09-30	Novartis Ag	Dérivés d'acide phosphonique butanoïque de bisphénol substitués en qualité d'inhibiteurs de nep (endopeptidase neutre)
TN2016000031A1 (en)	2013-07-25	2017-07-05	Novartis Ag	Cyclic polypeptides for the treatment of heart failure
TW201518323A (zh)	2013-07-25	2015-05-16	Novartis Ag	合成ａｐｅｌｉｎ多肽之生物結合物
PE20171328A1 (es)	2015-01-23	2017-09-12	Novartis Ag	Conjugados de acidos grasos y apelina sintetica con mayor vida media
JOP20190086A1 (ar)	2016-10-21	2019-04-18	Novartis Ag	مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب
CA3040803A1 (en) *	2016-10-27	2018-05-03	Damian Pharma Ag	Aldosterone synthase inhibitor
UY38072A (es)	2018-02-07	2019-10-01	Novartis Ag	Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
EP3787623A1 (en)	2018-05-03	2021-03-10	Damian Pharma AG	R-fadrozole for use in the treatment of aldostonerism
WO2020110011A1 (en)	2018-11-27	2020-06-04	Novartis Ag	Cyclic peptides as proprotein convertase subtilisin/kexin type 9 (pcsk9) inhibitors for the treatment of metabolic disorders
CN113166101A (zh)	2018-11-27	2021-07-23	诺华股份有限公司	作为治疗代谢障碍的蛋白质原转换酶枯草杆菌蛋白酶/kexin 9型（PCSK9）抑制剂的环状五聚体化合物
UY38485A (es)	2018-11-27	2020-06-30	Novartis Ag	Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación
WO2023084449A1 (en)	2021-11-12	2023-05-19	Novartis Ag	Diaminocyclopentylpyridine derivatives for the treatment of a disease or disorder
AR127698A1 (es)	2021-11-23	2024-02-21	Novartis Ag	Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno
WO2024241229A1 (en)	2023-05-24	2024-11-28	Novartis Ag	Naphthyridinone derivatives for the treatment of a disease or disorder

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2001
- 2001-04-10 MX MXPA02010091A patent/MXPA02010091A/es not_active Application Discontinuation
- 2001-04-10 AR ARP010101698A patent/AR032316A1/es not_active Application Discontinuation
- 2001-04-10 HU HU0301335A patent/HUP0301335A3/hu unknown
- 2001-04-10 RU RU2002129569/15A patent/RU2002129569A/ru not_active Application Discontinuation
- 2001-04-10 PL PL01358459A patent/PL358459A1/xx not_active Application Discontinuation
- 2001-04-10 CN CN01807917A patent/CN1422152A/zh active Pending
- 2001-04-10 SK SK1461-2002A patent/SK14612002A3/sk unknown
- 2001-04-10 EP EP01940317A patent/EP1282410A2/en not_active Withdrawn
- 2001-04-10 NZ NZ521855A patent/NZ521855A/en unknown
- 2001-04-10 JP JP2001574092A patent/JP2003530343A/ja active Pending
- 2001-04-10 KR KR1020027013486A patent/KR20020089437A/ko not_active Ceased
- 2001-04-10 AU AU7393801A patent/AU7393801A/xx active Pending
- 2001-04-10 IL IL15208101A patent/IL152081A0/xx unknown
- 2001-04-10 BR BR0110079-3A patent/BR0110079A/pt not_active IP Right Cessation
- 2001-04-10 AU AU2001273938A patent/AU2001273938B2/en not_active Ceased
- 2001-04-10 PE PE2001000328A patent/PE20020082A1/es not_active Application Discontinuation
- 2001-04-10 WO PCT/EP2001/004116 patent/WO2001076574A2/en not_active Application Discontinuation
- 2001-04-10 CA CA002405895A patent/CA2405895A1/en not_active Abandoned
2002
- 2002-10-11 ZA ZA200208204A patent/ZA200208204B/en unknown
- 2002-10-11 NO NO20024920A patent/NO20024920L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2405895A1 (en)	2001-10-18
KR20020089437A (ko)	2002-11-29
PE20020082A1 (es)	2002-02-21
WO2001076574A2 (en)	2001-10-18
CN1422152A (zh)	2003-06-04
RU2002129569A (ru)	2004-03-27
NZ521855A (en)	2004-10-29
AU2001273938B2 (en)	2005-03-03
HUP0301335A3 (en)	2006-02-28
NO20024920D0 (no)	2002-10-11
HUP0301335A2 (hu)	2003-08-28
IL152081A0 (en)	2003-05-29
SK14612002A3 (sk)	2003-05-02
EP1282410A2 (en)	2003-02-12
BR0110079A (pt)	2002-12-31
AU7393801A (en)	2001-10-23
AR032316A1 (es)	2003-11-05
WO2001076574A3 (en)	2002-04-25
ZA200208204B (en)	2003-10-14
PL358459A1 (en)	2004-08-09
JP2003530343A (ja)	2003-10-14
NO20024920L (no)	2002-11-27

Publication	Publication Date	Title
AU2001273938B2 (en)	2005-03-03	Novel medical use of aldosterone synthase inhibitors alone or in combination with ati-receptor antagonists
EP1341533B1 (en)	2006-02-15	Synergistic combinations comprising a renin inhibitor for cardiovascular diseases
AU2001273938A1 (en)	2002-01-10	Novel medical use of aldosterone synthase inhibitors alone or in combination with ati-receptor antagonists
US20090036432A1 (en)	2009-02-05	Combinations of AT1-antagonists, amiloride or triamterine, and a diuretic
US20040204444A1 (en)	2004-10-14	Combination of organic compounds
NZ534086A (en)	2006-08-31	Use of an aldosterone synthase inhibitor in combination with an angiotensin I receptor antagonist or an angiotensin I receptor antagonist plus a diuretic to treat various conditions
HK1059212B (zh)	2006-12-08	含有腎素抑制劑的，用於心血管疾病治療的增效組合物
MXPA06004933A (en)	2006-10-17	Combinations of at1-antagonists, amiloride or triamterine, and a diuretic
HK1089356B (zh)	2009-04-30	用於心血管疾病的包含一種高血壓酶原抑制劑的協同組合物
HK1053429A (zh)	2003-10-24	有機化合物的聯合形式

Legal Events

Date	Code	Title	Description
2013-09-30	FA	Abandonment or withdrawal