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MX9306841A - Vacuna a base de ureasa contra la infeccion por helicobacter en mamiferos. - Google Patents

Vacuna a base de ureasa contra la infeccion por helicobacter en mamiferos.

Info

Publication number
MX9306841A
MX9306841A MX9306841A MX9306841A MX9306841A MX 9306841 A MX9306841 A MX 9306841A MX 9306841 A MX9306841 A MX 9306841A MX 9306841 A MX9306841 A MX 9306841A MX 9306841 A MX9306841 A MX 9306841A
Authority
MX
Mexico
Prior art keywords
mammals
vaccine against
based vaccine
helicobacter infection
against helicobacter
Prior art date
Application number
MX9306841A
Other languages
English (en)
Inventor
Pierre Michetti
Andre Blum
Catherine Davin
Rainer Haas
Irene Corthesy-Theulaz
Jean-Pierre Kraehenbuhl
Emilia Saraga
Original Assignee
Fundation Pour La Rech Des Mal
Gastro Intestinales Gastrofond
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25517797&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9306841(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fundation Pour La Rech Des Mal, Gastro Intestinales Gastrofond filed Critical Fundation Pour La Rech Des Mal
Publication of MX9306841A publication Critical patent/MX9306841A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe un método para provocar en un huésped mamífero una respuestainmunoprotectora a la infección por Helicobacter, mediante laadministración al huésped de una cantidad inmunológicamente efectiva deuna ureasa de Helicobacter o subunidades de ureasa como antígeno. Seproporcionan también las composiciones de vacuna.
MX9306841A 1992-11-03 1993-11-03 Vacuna a base de ureasa contra la infeccion por helicobacter en mamiferos. MX9306841A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97099692A 1992-11-03 1992-11-03
US08/085,938 US5972336A (en) 1992-11-03 1993-07-06 Urease-based vaccine against helicobacter infection

Publications (1)

Publication Number Publication Date
MX9306841A true MX9306841A (es) 1995-01-31

Family

ID=25517797

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306841A MX9306841A (es) 1992-11-03 1993-11-03 Vacuna a base de ureasa contra la infeccion por helicobacter en mamiferos.

Country Status (29)

Country Link
US (1) US5972336A (es)
EP (2) EP1170016A3 (es)
JP (1) JPH07503255A (es)
KR (1) KR100287424B1 (es)
CN (1) CN1111429C (es)
AT (1) ATE217196T1 (es)
AU (2) AU678195C (es)
BR (1) BR9305711A (es)
CA (1) CA2127283A1 (es)
CZ (1) CZ284416B6 (es)
DE (1) DE69331901T2 (es)
DK (1) DK0625053T3 (es)
ES (1) ES2176232T3 (es)
FI (1) FI112032B (es)
GE (1) GEP20012429B (es)
HU (1) HU219760B (es)
IL (1) IL107474A (es)
MX (1) MX9306841A (es)
NO (1) NO942490L (es)
NZ (2) NZ258118A (es)
OA (1) OA10087A (es)
PL (1) PL174448B1 (es)
PT (1) PT625053E (es)
RO (1) RO114870B1 (es)
RU (1) RU2125891C1 (es)
SG (1) SG70978A1 (es)
SK (1) SK280619B6 (es)
WO (1) WO1994009823A1 (es)
ZA (1) ZA938203B (es)

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FR2682122B1 (fr) * 1991-10-03 1995-06-09 Pasteur Institut Nouveaux genes d'helicobacter pylori. leur utilisation pour la preparation de souches recombinantes de h. pylori.
US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
JPH08509873A (ja) 1993-05-19 1996-10-22 アンスティテュ・パストゥール ヘリコバクター感染に対する免疫組成物、該組成物に用いられるポリペプチドおよび該ポリペプチドをコードする核酸配列
US5843460A (en) * 1993-05-19 1998-12-01 Institut Pasteur Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
US6406703B1 (en) 1993-07-27 2002-06-18 Csl Limited Treatment of H. pylori associated gastroduodenal disease
ATE244578T1 (de) * 1993-07-27 2003-07-15 Csl Ltd Behandlung eines durch helicobakter verursachten gastroduodenalen krankheit
AUPM612494A0 (en) 1994-06-08 1994-06-30 Csl Limited Treatment or prevention of helicobacter infection
AU702878B2 (en) * 1994-06-08 1999-03-11 Csl Limited Treatment and prevention of helicobacter infection
EP0769018B1 (en) * 1994-07-01 2002-12-18 Chiron Corporation Helicobacter proteins and vaccines
AU723063B2 (en) * 1995-04-28 2000-08-17 Oravax, Inc Multimeric, recombinant urease vaccine
US5837240A (en) * 1995-04-28 1998-11-17 Oravax-Merieux Co. Multimeric, recombinant urease vaccine
EP0840796A2 (en) * 1995-07-26 1998-05-13 Maxim Pharmaceuticals Mucosal delivery of polynucleotides
GB2307987A (en) * 1995-12-06 1997-06-11 Univ Manchester Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto
US6248551B1 (en) * 1997-03-28 2001-06-19 Institut Pasteur Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides
US20020026035A1 (en) * 1997-04-01 2002-02-28 Harold Kleanthous Helicobacter ghpo 1360 and ghpo 750 polypeptides and corresponding polynucleotide molecules
WO1998049318A1 (fr) * 1997-04-30 1998-11-05 Pasteur Merieux Serums & Vaccins Composition vaccinale anti-helicobacter a base d'adn
US20030158396A1 (en) * 1997-07-29 2003-08-21 Harold Kleanthous Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome
US5985631A (en) 1997-09-12 1999-11-16 Oravax-Merieux Co. Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US20020151462A1 (en) * 1998-02-19 2002-10-17 Ling Lissolo Helicobacter pylori membrane proteins
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
AU770498B2 (en) 1998-06-19 2004-02-26 Merieux Oravax LT and CT in parenteral immunization methods against helicobacter infection
US6190667B1 (en) 1998-06-30 2001-02-20 Institut Pasteur Methods of inhibiting Helicobacter pylori
WO2000003730A1 (en) * 1998-07-16 2000-01-27 Cheil Jedang Corporation Urease based vaccine against helicobacter infection
WO2000045847A1 (en) * 1999-02-05 2000-08-10 Alk-Abelló A/S Novel mucosal delivery system
US7384640B1 (en) * 1999-09-30 2008-06-10 Wyeth Holdings Corporation Mutant cholera holotoxin as an adjuvant
US20020051794A1 (en) 2000-08-09 2002-05-02 Alk-Abello A/S Novel parenteral vaccine formulations and uses thereof
US20020107368A1 (en) * 2000-12-07 2002-08-08 Jing-Hui Tian Helicobacter proteins, gene sequences and uses thereof
AUPR524101A0 (en) * 2001-05-25 2001-06-21 Council Of The Queensland Institute Of Medical Research, The Antigen targeting
JP2005508143A (ja) 2001-06-07 2005-03-31 ワイス・ホールデイングス・コーポレーシヨン アジュバントとしてのコレラホロトキシンの突然変異形
ATE451386T1 (de) * 2001-06-07 2009-12-15 Wyeth Corp Mutantenformen von cholera holotoxin als adjuvans
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
ES2434732T3 (es) 2004-12-15 2013-12-17 Janssen Alzheimer Immunotherapy Anticuerpos para beta-amiloide humanizados para su uso en mejorar la cognición
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
CN100460014C (zh) * 2006-07-20 2009-02-11 中国人民解放军第三军医大学 基于尿素酶b亚单位活性片段的幽门螺杆菌疫苗及其制备方法
WO2008055316A1 (en) * 2006-11-10 2008-05-15 Marshall Barry J Methods and devices for the delivery of peptides into the gastric mucosa
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
PT2182983E (pt) 2007-07-27 2014-09-01 Janssen Alzheimer Immunotherap Tratamento de doenças amiloidogénicas com anticorpos anti-abeta humanizados
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
KR100982489B1 (ko) * 2007-12-17 2010-09-15 대구한의대학교산학협력단 헬리코박터 파일로리로부터 유래된 항원을 이용하여헬리코박터 파일로리 특이 항체 생산을 위한 백신을제조하는 방법
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
PL218700B1 (pl) 2012-03-29 2015-01-30 Gdański Univ Medyczny Doustna szczepionka zawierająca przetrwalniki Bacillus subtilis oraz jej zastosowanie do immunizacji przeciwko Helicobacter pylori
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
EP2837939A1 (en) * 2013-08-13 2015-02-18 Technische Universität München Method for the detection of H.pylori infection
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US5268276A (en) * 1988-09-16 1993-12-07 Jan Holmgren Recombinant systems for expression of cholera B-sub-unit with the aid of foreign promoters and/or leader peptides
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US5443832A (en) * 1990-04-16 1995-08-22 Institut Swisse De Recherches Experimentales Sur Le Cancer Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
JPH04169539A (ja) * 1990-11-01 1992-06-17 Imuno Japan:Kk 消化器疾患治療・予防剤およびその製造方法
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US5837240A (en) * 1995-04-28 1998-11-17 Oravax-Merieux Co. Multimeric, recombinant urease vaccine

Also Published As

Publication number Publication date
AU2003270987A1 (en) 2004-01-22
PL304419A1 (en) 1995-01-09
DK0625053T3 (da) 2002-08-12
DE69331901D1 (de) 2002-06-13
DE69331901T2 (de) 2002-10-31
HU9402261D0 (en) 1994-10-28
SK280619B6 (sk) 2000-05-16
NZ299149A (en) 1997-12-19
EP0625053B1 (en) 2002-05-08
EP1170016A2 (en) 2002-01-09
PT625053E (pt) 2002-09-30
RO114870B1 (ro) 1999-08-30
EP0625053A1 (en) 1994-11-23
OA10087A (en) 1996-12-18
FI943171A0 (fi) 1994-07-01
HUT69938A (en) 1995-09-28
KR100287424B1 (ko) 2001-04-16
WO1994009823A1 (en) 1994-05-11
ZA938203B (en) 1994-06-09
CN1094640A (zh) 1994-11-09
RU2125891C1 (ru) 1999-02-10
US5972336A (en) 1999-10-26
ES2176232T3 (es) 2002-12-01
AU5561994A (en) 1994-05-24
NO942490L (no) 1994-08-22
SG70978A1 (en) 2000-03-21
ATE217196T1 (de) 2002-05-15
CN1111429C (zh) 2003-06-18
FI943171L (fi) 1994-09-01
SK79394A3 (en) 1996-09-04
AU678195B2 (en) 1997-05-22
GEP20012429B (en) 2001-05-25
EP1170016A3 (en) 2002-03-06
PL174448B1 (pl) 1998-07-31
JPH07503255A (ja) 1995-04-06
NO942490D0 (no) 1994-07-01
AU678195C (en) 2003-06-12
CZ284416B6 (cs) 1998-11-11
CA2127283A1 (en) 1994-05-11
FI112032B (fi) 2003-10-31
IL107474A (en) 1998-09-24
BR9305711A (pt) 1997-02-18
IL107474A0 (en) 1994-02-27
HU219760B (hu) 2001-07-30
NZ258118A (en) 1997-04-24
CZ160994A3 (en) 1995-04-12

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