MX348418B - Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada. - Google Patents
Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada.Info
- Publication number
- MX348418B MX348418B MX2014004347A MX2014004347A MX348418B MX 348418 B MX348418 B MX 348418B MX 2014004347 A MX2014004347 A MX 2014004347A MX 2014004347 A MX2014004347 A MX 2014004347A MX 348418 B MX348418 B MX 348418B
- Authority
- MX
- Mexico
- Prior art keywords
- composition containing
- bromfenac
- increased bioavailability
- ocular composition
- containing bromfenac
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/775—Phenolic resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describen las formulaciones y métodos que proporcionan penetración mejorada del bromfenaco dentro del tejido ocular cuando se administran tópicamente, en comparación a la formulación BROMDAYMR y el método actualmente disponibles, cuando se administra tópicamente. Las formulaciones y los métodos lo hicieron así mientras conservaron la conveniencia del paciente de una administración vez al día y disminuyeron ventajosamente la concentración del bromfenaco dosificado al paciente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161546290P | 2011-10-12 | 2011-10-12 | |
| PCT/US2012/059653 WO2013055856A1 (en) | 2011-10-12 | 2012-10-11 | Ocular composition containing bromfenac with increased bioavailability |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014004347A MX2014004347A (es) | 2014-07-28 |
| MX348418B true MX348418B (es) | 2017-06-12 |
Family
ID=47073541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014004347A MX348418B (es) | 2011-10-12 | 2012-10-11 | Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada. |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9517220B2 (es) |
| EP (2) | EP2765988B9 (es) |
| CA (1) | CA2852995C (es) |
| ES (1) | ES2992712T3 (es) |
| FI (1) | FI2765988T3 (es) |
| HR (1) | HRP20241509T1 (es) |
| LT (1) | LT2765988T (es) |
| MX (1) | MX348418B (es) |
| PL (1) | PL2765988T3 (es) |
| PT (1) | PT2765988T (es) |
| SI (1) | SI2765988T1 (es) |
| WO (1) | WO2013055856A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2301964T3 (es) * | 2003-01-21 | 2008-07-01 | Senju Pharmaceutical Co., Ltd. | Preparado liquido acuoso que contiene acido 2-amino-3-(4-bromobenzoil)fenilacetico. |
| US8778999B2 (en) | 2009-03-05 | 2014-07-15 | Insite Vision Incorporated | Non-steroidal anti-inflammatory ophthalmic compositions |
| US20160143869A1 (en) | 2013-06-19 | 2016-05-26 | Sentiss Research Center | Stable bromfenac solution |
| WO2015087267A2 (en) | 2013-12-12 | 2015-06-18 | Sentiss Pharma Private Limited | Stable bromfenac ophthalmic solution |
| ES2538551B1 (es) * | 2013-12-20 | 2016-01-13 | Eurocanarias Oftalmológica, Sl | Composición Oftálmica para la corrección de la presbicia |
| CN104151182B (zh) * | 2014-06-16 | 2016-03-30 | 广东众生药业股份有限公司 | 一种溴芬酸钠倍半水合物的制备方法 |
| IT202000002296A1 (it) * | 2020-02-06 | 2021-08-06 | Sifi Spa | Formulazioni topiche oftalmiche a base di xantano con ridotta posologia |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5558876A (en) * | 1995-03-29 | 1996-09-24 | Alcon Laboratories, Inc. | Topical ophthalmic acidic drug formulations |
| US5942508A (en) * | 1997-02-04 | 1999-08-24 | Senju Pharmaceutical Co., Ltd. | Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid |
| US6552020B1 (en) * | 1999-07-30 | 2003-04-22 | Allergan, Inc. | Compositions including antibiotics and methods for using same |
| ES2301964T3 (es) | 2003-01-21 | 2008-07-01 | Senju Pharmaceutical Co., Ltd. | Preparado liquido acuoso que contiene acido 2-amino-3-(4-bromobenzoil)fenilacetico. |
| US20080039398A1 (en) * | 2006-01-25 | 2008-02-14 | Ousler George W Iii | Formulations and methods for treating dry eye |
| US20070297981A1 (en) | 2006-01-25 | 2007-12-27 | Ousler George W Iii | Formulations and methods for treating dry eye |
| US20070299124A1 (en) * | 2006-01-25 | 2007-12-27 | Ousler George W Iii | Formulations and methods for treating dry eye |
| US20110054031A1 (en) | 2008-02-21 | 2011-03-03 | Ista Pharmaceuticals, Inc. | Ophthalmic NSAIDS as Adjuvants |
| US20100008993A1 (en) * | 2008-07-14 | 2010-01-14 | Proksch Joel W | Compositions and Methods for Increasing Bioavailability of Topical Ophthalmic Drugs |
| US8778999B2 (en) * | 2009-03-05 | 2014-07-15 | Insite Vision Incorporated | Non-steroidal anti-inflammatory ophthalmic compositions |
| BR112012010936A2 (pt) * | 2009-11-11 | 2017-10-17 | Micro Labs Ltd | combinação farmacêutica de composto de protaglandina e nsaid para o tratamento de glaucoma e hipertensão ocular |
| ES2657845T3 (es) * | 2010-04-09 | 2018-03-07 | Allergan, Inc. | Composiciones de ketorolaco para la cicatrización de heridas corneales |
-
2012
- 2012-10-11 EP EP12778008.8A patent/EP2765988B9/en active Active
- 2012-10-11 CA CA2852995A patent/CA2852995C/en not_active Expired - Fee Related
- 2012-10-11 MX MX2014004347A patent/MX348418B/es active IP Right Grant
- 2012-10-11 LT LTEPPCT/US2012/059653T patent/LT2765988T/lt unknown
- 2012-10-11 WO PCT/US2012/059653 patent/WO2013055856A1/en active Application Filing
- 2012-10-11 SI SI201232078T patent/SI2765988T1/sl unknown
- 2012-10-11 FI FIEP12778008.8T patent/FI2765988T3/fi active
- 2012-10-11 ES ES12778008T patent/ES2992712T3/es active Active
- 2012-10-11 EP EP24199704.8A patent/EP4491170A1/en active Pending
- 2012-10-11 PL PL12778008.8T patent/PL2765988T3/pl unknown
- 2012-10-11 US US13/649,271 patent/US9517220B2/en active Active
- 2012-10-11 PT PT127780088T patent/PT2765988T/pt unknown
- 2012-10-11 HR HRP20241509TT patent/HRP20241509T1/hr unknown
-
2016
- 2016-11-04 US US15/343,457 patent/US10085958B2/en active Active
-
2018
- 2018-08-21 US US16/107,174 patent/US20180353451A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT2765988T (pt) | 2024-11-14 |
| HRP20241509T1 (hr) | 2025-01-03 |
| EP2765988A1 (en) | 2014-08-20 |
| MX2014004347A (es) | 2014-07-28 |
| SI2765988T1 (sl) | 2025-01-31 |
| CA2852995C (en) | 2016-03-29 |
| EP2765988B1 (en) | 2024-09-18 |
| FI2765988T3 (fi) | 2024-11-13 |
| ES2992712T3 (en) | 2024-12-17 |
| US20180353451A1 (en) | 2018-12-13 |
| US10085958B2 (en) | 2018-10-02 |
| PL2765988T3 (pl) | 2025-02-10 |
| WO2013055856A1 (en) | 2013-04-18 |
| LT2765988T (lt) | 2024-11-25 |
| US9517220B2 (en) | 2016-12-13 |
| US20170049735A1 (en) | 2017-02-23 |
| EP2765988B9 (en) | 2025-01-08 |
| CA2852995A1 (en) | 2013-04-18 |
| EP4491170A1 (en) | 2025-01-15 |
| US20130096199A1 (en) | 2013-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |