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MX347150B - Anticuerpos especificos para claudina 6 (cldn6). - Google Patents

Anticuerpos especificos para claudina 6 (cldn6).

Info

Publication number
MX347150B
MX347150B MX2012005444A MX2012005444A MX347150B MX 347150 B MX347150 B MX 347150B MX 2012005444 A MX2012005444 A MX 2012005444A MX 2012005444 A MX2012005444 A MX 2012005444A MX 347150 B MX347150 B MX 347150B
Authority
MX
Mexico
Prior art keywords
cancer
cldn6
claudin
antibodies specific
sarcoma
Prior art date
Application number
MX2012005444A
Other languages
English (en)
Other versions
MX2012005444A (es
Inventor
Sahin Ugur
Türeci Özlem
Koslowski Michael
Walter Korden
Wöll Stefan
Kreuzberg Maria
Hubner Bernd
Erdeljan Michael
Original Assignee
Johannes Gutenberg-Universität Mainz *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP09014136A external-priority patent/EP2322555A1/en
Application filed by Johannes Gutenberg-Universität Mainz * filed Critical Johannes Gutenberg-Universität Mainz *
Publication of MX2012005444A publication Critical patent/MX2012005444A/es
Publication of MX347150B publication Critical patent/MX347150B/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C—CHEMISTRY; METALLURGY
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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Abstract

La presente invención se refiere a anticuerpos útiles como terapéuticos para tratar y/o prevenir enfermedades asociadas con células que expresan CLDN6, que incluyen enfermedad relacionada con tumores tal como cáncer de ovario, cáncer de pulmón, cáncer gástrico, cáncer de mama, cáncer hepático, cáncer pancreático, cáncer de piel, melanoma maligno, cáncer de cabeza y cuello, sarcoma, cáncer de vías biliares, cáncer de la vejiga urinaria, cáncer de riñón, cáncer de colon, coriocarcinoma placentario, cáncer de cuello uterino, cáncer testicular, y cáncer uterino.
MX2012005444A 2009-11-11 2010-11-11 Anticuerpos especificos para claudina 6 (cldn6). MX347150B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26020209P 2009-11-11 2009-11-11
EP09014136A EP2322555A1 (en) 2009-11-11 2009-11-11 Antibodies specific for claudin 6 (CLDN6)
US36161810P 2010-07-06 2010-07-06
EP10006956 2010-07-06
PCT/EP2010/006888 WO2011057788A1 (en) 2009-11-11 2010-11-11 Antibodies specific for claudin 6 (cldn6)

Publications (2)

Publication Number Publication Date
MX2012005444A MX2012005444A (es) 2012-06-19
MX347150B true MX347150B (es) 2017-04-17

Family

ID=43480734

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2017004846A MX385874B (es) 2009-11-11 2010-11-11 Anticuerpos especificos para claudina 6 (cldn6).
MX2012005444A MX347150B (es) 2009-11-11 2010-11-11 Anticuerpos especificos para claudina 6 (cldn6).
MX2020011790A MX2020011790A (es) 2009-11-11 2012-05-09 Anticuerpos especificos para claudina 6 (cldn6).

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2017004846A MX385874B (es) 2009-11-11 2010-11-11 Anticuerpos especificos para claudina 6 (cldn6).

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2020011790A MX2020011790A (es) 2009-11-11 2012-05-09 Anticuerpos especificos para claudina 6 (cldn6).

Country Status (29)

Country Link
US (5) US9487584B2 (es)
EP (4) EP4461354A3 (es)
JP (3) JP5889196B2 (es)
KR (4) KR102317098B1 (es)
CN (4) CN111875703B (es)
AU (3) AU2010318316B2 (es)
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