[go: up one dir, main page]

MX2016013873A - Metodo para eliminar bacterias de la sangre usando alta velocidad de flujo. - Google Patents

Metodo para eliminar bacterias de la sangre usando alta velocidad de flujo.

Info

Publication number
MX2016013873A
MX2016013873A MX2016013873A MX2016013873A MX2016013873A MX 2016013873 A MX2016013873 A MX 2016013873A MX 2016013873 A MX2016013873 A MX 2016013873A MX 2016013873 A MX2016013873 A MX 2016013873A MX 2016013873 A MX2016013873 A MX 2016013873A
Authority
MX
Mexico
Prior art keywords
bacteria
blood
flow rate
high flow
removing bacteria
Prior art date
Application number
MX2016013873A
Other languages
English (en)
Inventor
Mccrea Keith
Ward Robert
Original Assignee
Exthera Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exthera Medical Corp filed Critical Exthera Medical Corp
Publication of MX2016013873A publication Critical patent/MX2016013873A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692—Washing or rinsing blood or blood constituents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28023—Fibres or filaments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0057—Special media to be introduced, removed or treated retained by adsorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/20—Pathogenic agents
    • A61M2202/203—Bacteria
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/62—In a cartridge

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Cell Biology (AREA)
  • External Artificial Organs (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención proporciona métodos para la eliminación de una cantidad significativa de bacterias (por ejemplo, bacterias gram-negativas y bacterias gram-positivas, incluyendo bacterias sin o con baja afinidad para sulfato de heparano) de sangre entera, suero o plasma usando un medio de adsorción. El método puede ser usado en tratamientos extracorpóreos que impliquen altas velocidades de flujo volumétrico y altas velocidades de flujo lineal.
MX2016013873A 2014-04-24 2015-04-17 Metodo para eliminar bacterias de la sangre usando alta velocidad de flujo. MX2016013873A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461984013P 2014-04-24 2014-04-24
PCT/US2015/026340 WO2015164198A1 (en) 2014-04-24 2015-04-17 Method for removing bacteria from blood using high flow rate

Publications (1)

Publication Number Publication Date
MX2016013873A true MX2016013873A (es) 2017-03-09

Family

ID=54333028

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016013873A MX2016013873A (es) 2014-04-24 2015-04-17 Metodo para eliminar bacterias de la sangre usando alta velocidad de flujo.

Country Status (12)

Country Link
US (2) US20170035956A1 (es)
EP (1) EP3134146B1 (es)
JP (3) JP2017513636A (es)
KR (1) KR20170020749A (es)
CN (1) CN106255520B (es)
AU (2) AU2015250107A1 (es)
BR (1) BR112016024569B1 (es)
CA (1) CA2946294C (es)
DE (1) DE15782250T1 (es)
ES (1) ES2625351T3 (es)
MX (1) MX2016013873A (es)
WO (1) WO2015164198A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX344592B (es) 2005-12-13 2016-12-20 Exthera Medical Corp Metodo para eliminar extracorporalmente de la sangre un microbio patogeno, una celula inflamatoria o una proteina inflamatoria.
EP2509604B1 (en) 2009-12-01 2021-03-17 ExThera Medical Corporation Device for removing cytokines from blood with surface immobilized polysaccharides
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
EP2861273B1 (en) 2012-06-13 2017-08-23 ExThera Medical Corporation Use of heparin and carbohydrates to treat cancer
HK1216625A1 (zh) 2013-06-24 2016-11-25 Exthera Medical Corporation 含有塗覆甘露糖的基質的血液過濾系統
AU2014346668C1 (en) 2013-11-08 2018-04-26 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
EP3134146B1 (en) 2014-04-24 2024-12-25 ExThera Medical Corporation Method for removing bacteria from blood using high flow rate
CN106714669B (zh) 2014-09-22 2021-05-14 艾克塞拉医疗公司 可穿戴的血液灌流装置
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
EP3422943A4 (en) 2016-03-02 2019-10-16 ExThera Medical Corporation METHOD OF TREATING DRUG ENTRIES
AU2017272021B2 (en) * 2016-05-26 2021-09-02 Cytosorbents Corporation The use of a Hemocompatible porous polymer bead sorbent for removal of Endotoxemia-inducing molecules
US20190329188A1 (en) * 2016-11-29 2019-10-31 Gambro Lundia Ab Membrane for the adsorption of bacteria
EP3388140A1 (en) * 2017-04-10 2018-10-17 Gambro Lundia AB Extracorporeal blood circuit
AU2018346535A1 (en) * 2017-10-05 2020-04-30 Minnetronix, Inc. Systems, catheters, and methods for treating along the central nervous system
JP7429343B2 (ja) 2018-01-05 2024-02-08 パス イーエックス，インク． 流体からの疾患材料の捕捉および除去のためのデバイス
EP3969014A4 (en) 2019-05-16 2023-01-25 ExThera Medical Corporation METHODS OF MODULATION OF ENDOTHELIAL GLYCOCALYX STRUCTURE
KR102419508B1 (ko) * 2020-10-14 2022-07-11 대전보건대학교 산학협력단 신규한 메티실린-내성 황색포도상구균 검출 방법 및 이의 용도
JP2023550942A (ja) * 2020-11-30 2023-12-06 アルテコ メディカル アクティエボラーグ 体液から少なくとも１つの成分を結合及び分離するための装置
CN114011389B (zh) * 2021-12-08 2023-10-31 广州康盛生物科技股份有限公司 一种用于脓毒血症的血液净化材料及其制备方法和应用
KR20240094339A (ko) * 2022-12-16 2024-06-25 서울대학교산학협력단 병원 내 2차 감염을 감소시키기 위한 혈액관류장치
WO2024177096A1 (ja) 2023-02-21 2024-08-29 東レ株式会社 中空糸膜及び中空糸膜モジュール
WO2025117428A1 (en) * 2023-11-29 2025-06-05 Exthera Medical Corporation Fluidized bed extracorporeal treatment device

Family Cites Families (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3782382A (en) 1972-02-03 1974-01-01 K N Enterprises Inc Means for blood administration and the like
US4103685A (en) 1976-01-05 1978-08-01 Lupien Paul J Method and apparatus for extravascular treatment of blood
JPS54127493U (es) 1978-02-25 1979-09-05
US4430496A (en) 1980-01-17 1984-02-07 Varian Associates, Inc. Strong anion exchange composition and methods
US4415665A (en) 1980-12-12 1983-11-15 Pharmacia Fine Chemicals Ab Method of covalently binding biologically active organic substances to polymeric substances
JPS5853757A (ja) 1981-09-25 1983-03-30 Denki Kagaku Kogyo Kk 免疫アフイニテイクロマトグラフイ−用吸着体及びその製法
SE8200751L (sv) 1982-02-09 1983-08-10 Olle Larm Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
JPS58146354A (ja) 1982-02-26 1983-08-31 日機装株式会社 体液浄化器の製造法
US4820302A (en) 1982-04-22 1989-04-11 Sterling Drug Inc. Bio compatible and blood compatible materials and methods
CA1221307A (en) 1982-12-02 1987-05-05 Nobutaka Tani Adsorbent and process for preparing the same
JPS59227827A (ja) 1983-06-10 1984-12-21 Nippon Koutai Kenkyusho:Kk マラリア原虫由来糖鎖関連抗原及びその製造法
FR2558063B1 (fr) 1984-01-18 1987-02-20 Hospal Ind Rein artificiel a aiguille unique
DE3609021A1 (de) 1985-03-25 1986-09-25 Bio-Rad Laboratories, Inc., Richmond, Calif. Chromatographisches trennmedium fuer die schnelle analyse von kleinen proben
DE3519011A1 (de) 1985-05-25 1986-11-27 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines materials zur affinitaetschromatographie
DE3880647T2 (de) 1987-11-20 1993-11-18 Kanegafuchi Chemical Ind Sorbentmittel für Serum-Amyloid-Proteine.
US4955870A (en) 1988-08-23 1990-09-11 Ridderheim Kristen A Hypodermic syringe with retractable needle
JPH0489500A (ja) 1990-07-31 1992-03-23 Kirin Brewery Co Ltd アフィニティクロマトグラフィーによる物質の精製法および精製装置
US5227049A (en) 1990-08-20 1993-07-13 Hospal Industrie Single-needle circuit for circulating blood outside the body in blood treatment apparatus
FR2672219B1 (fr) 1991-02-06 1998-09-11 Hospal Ind Procede de commande de la circulation du sang dans un circuit a aiguille unique.
SE469256B (sv) 1991-02-18 1993-06-14 Medscand Ab Rengoeringsprodukt
US5324823A (en) 1991-03-26 1994-06-28 Otsuka Pharmaceutical Factory, Inc. Adsorbent for cellular fibronectin and a method for fractional purification of fibronectin
US5211850A (en) 1991-07-26 1993-05-18 Research Medical, Inc. Plasma filter sorbent system for removal of components from blood
DE4217917A1 (de) 1992-05-30 1993-12-02 Job Prof Dr Med Harenberg Immobilisation von chemisch kovalent gebundenem Heparin an Polymere mit Arylresten im Polymer
DE4331358A1 (de) 1992-10-12 1994-04-14 Braun Melsungen Ag Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten
US5344455A (en) * 1992-10-30 1994-09-06 Medtronic, Inc. Graft polymer articles having bioactive surfaces
US5437861A (en) 1993-03-16 1995-08-01 Applied Immune Sciences, Inc. Removal of selected factors from whole blood or its components; and prevention and treatment of septic shock syndrome
NO931809L (no) 1993-05-19 1994-11-21 Norsk Hydro As Hemofilter
US5447859A (en) 1993-07-16 1995-09-05 Viagene Method for the purification or removal of retroviruses using sulfated cellulose
US5753227A (en) 1993-07-23 1998-05-19 Strahilevitz; Meir Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases
CA2168038A1 (en) 1993-08-19 1995-02-23 Jerald K. Rasmussen Heparin functional affinity supports
JPH07178161A (ja) 1993-12-24 1995-07-18 Terumo Corp 医療器具
SE9501056D0 (sv) 1995-03-23 1995-03-23 Probi Ab Epithelial adherent lactobacilli
US6312907B1 (en) 1995-04-24 2001-11-06 The Texas A & M University System DbpA compositions and methods of use
DE19515554C2 (de) 1995-04-27 1999-06-17 Braun Melsungen Ag Verwendung eines Mittels und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
DE69638094D1 (de) 1995-06-07 2010-01-21 Cerus Corp Verfahren und vorrichtungen zur entfernung von psoralenen aus blutprodukten.
AU708196B2 (en) 1995-06-20 1999-07-29 Johannes Schumacher Process and device for determining the activity of enzymes in liquids, or the concentration and/or activity of inhibitors in liquids
CA2200119C (en) 1996-03-18 2005-08-16 Masaru Nakatani Adsorbent for removing chemokine, method for removing the same, and adsorber for the same
RU2089283C1 (ru) 1996-03-23 1997-09-10 Научно-исследовательская фирма "Ультрасан" Био-, гемосовместимые сорбенты на основе сверхсшитых полимеров стирола с модифицированной поверхностью, способ их получения (варианты) и способ получения матрицы сорбента
SE507028C2 (sv) 1996-08-06 1998-03-16 Medicarb Ab Ny medicinsk användning
WO1998029727A2 (en) 1996-12-31 1998-07-09 Stephon, Robert, L. Microsphere-enhanced immunoassay for the detection of veterinary diseases
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
CA2284619A1 (en) 1997-03-25 1998-10-01 Kaneka Corporation Absorbent for eliminating hepatitis c virus, absorber, and absorption method
WO1998053829A1 (en) 1997-05-27 1998-12-03 Akzo Nobel N.V. Use of oligosaccharide for preventing blood clotting in extracorporeal blood circuits
US6465170B2 (en) 1997-06-13 2002-10-15 Baxter Aktiengesellschaft Method for depleting viral and molecular pathogens in a biological material
US6197568B1 (en) 1997-07-29 2001-03-06 The Regents Of The University Of Michigan Method and compositions for isolation, diagnosis and treatment of polyanion-binding microorganisms
US20020159995A1 (en) 1997-07-30 2002-10-31 Renal Tech International Devices, systems, and methods for reducing levels of pro-inflammatory or anti-inflammatory stimulators or mediators in the blood, generated as a result of extracorporeal blood processing
US20020197249A1 (en) 2001-04-10 2002-12-26 Renal Tech International Devices, systems, and methods for reducing levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood products
US20020197250A1 (en) 2001-04-10 2002-12-26 Renal Tech International Biocompatible devices, systems, and methods for reducing levels of pro-inflammatory or anti-inflammatory stimulators or mediators in the blood
US6053894A (en) 1997-08-04 2000-04-25 Shadd, Jr.; Daniel L. Hypodermic syringe
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US6136424A (en) 1998-02-06 2000-10-24 Renal Tech International, Llc Method of and material for purification of physiological liquids of organism, and method of producing the material
GB9804632D0 (en) 1998-03-05 1998-04-29 Cantab Pharma Res Virus preparations and methods
US8197430B1 (en) 1998-05-22 2012-06-12 Biopheresis Technologies, Inc. Method and system to remove cytokine inhibitor in patients
US6248127B1 (en) 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device
JP2000086688A (ja) 1998-09-04 2000-03-28 Ngk Insulators Ltd パルボウイルス吸着糖鎖リガンドおよびこれを利用したパルボウイルス除去装置
NO984143L (no) 1998-09-09 2000-03-10 Norsk Hydro As Ny prosess for å fremstille overflatemodifiserende stoffer
WO2000023792A1 (en) 1998-10-19 2000-04-27 Cbd Technologies Ltd. Methods of concentrating microorganisms using affinity separation
ES2372580T3 (es) 1998-12-24 2012-01-24 Toray Industries, Inc. Columna para purificar sangre.
JP2000217575A (ja) 1999-02-01 2000-08-08 Masashi Funayama 生理活性物質、ヒト血球分化細胞およびヒト細胞の吸着体。
DE19916352A1 (de) 1999-04-12 2000-10-19 Braun Melsungen Ag Entfernung von hüllehaltigen Viren aus Blut, Plasma oder Serum
SE515295C2 (sv) 1999-11-23 2001-07-09 Medicarb Ab Förfarande för framställning av konjugat av en biologiskt aktiv polysackarid och ett fast substrat, samt sådana konjugat
JP2001178817A (ja) 1999-12-24 2001-07-03 Terumo Corp 人工腎臓用装置およびこれを用いた品質評価装置ならびに流体回路
US7067060B2 (en) * 2000-01-11 2006-06-27 Nephros, Inc. Ionic enhanced dialysis/diafiltration system
JP2001190273A (ja) 2000-01-14 2001-07-17 Jsr Corp ウイルス濃縮用粒子、該粒子を使用するウイルス濃縮方法およびウイルス検出方法
GB0001450D0 (en) 2000-01-21 2000-03-08 Genpoint As Cell isolation method
ES2287006T3 (es) 2000-03-06 2007-12-16 Dade Behring Marburg Gmbh Vehiculos revestidos con polisacaridos, su preparacion y uso.
EP1192963A4 (en) 2000-04-05 2004-08-25 Toray Industries ADSORBENTS FOR PROTEINS OF THE HIGH MOBILITY PROTEIN AND PILLAR GROUP FOR CLEANING BODY LIQUIDS
US7181261B2 (en) 2000-05-15 2007-02-20 Silver James H Implantable, retrievable, thrombus minimizing sensors
DE10045434B4 (de) 2000-09-14 2005-07-14 Fresenius Hemocare Gmbh Adsorbens mit unterschiedlich modifizierten Oberflächenbereichen, Verfahren zu dessen Herstellung und Verwendung davon
JP4283430B2 (ja) 2000-09-26 2009-06-24 株式会社カネカ エンテロトキシンの吸着材、吸着除去方法および吸着器
US8178304B2 (en) 2000-10-06 2012-05-15 Smith Terry J Diagnostic methods relating to Graves' disease and other autoimmune disorders
US8153121B2 (en) 2000-10-06 2012-04-10 Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center Diagnosis and therapy of antibody-mediated inflammatory autoimmune disorders
US6509104B2 (en) 2000-12-05 2003-01-21 Michigan Biotechnology Institute Antithrombogenic polymer coating
WO2002053251A1 (en) 2000-12-29 2002-07-11 Upfront Chromatography A/S Extracorporeal capturing of specific bio-macromolecular entities from extracellular body fluids
KR100804542B1 (ko) 2001-01-30 2008-02-20 가부시키가이샤 가네카 직접 혈액관류가 가능한 체액 처리기
DE10117043A1 (de) 2001-04-05 2002-11-07 Gerhard Puetz Verfahren zur Eliminierung von potentiell toxischen und/oder schädlichen Stoffen
US20020197252A1 (en) 2001-04-10 2002-12-26 Renal Tech International Selective adsorption devices and systems
US6773412B2 (en) 2001-04-13 2004-08-10 Chf Solutions, Inc. User interface for blood treatment device
JP2003128502A (ja) 2001-10-18 2003-05-08 Noritake Co Ltd 有害物質の処理材およびその製造方法
CA2463422A1 (en) 2001-10-10 2003-04-24 Koushi Yamaguchi Photocatalytic material selectively inactivating biologically harmful substance and utilization thereof
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
US20030148017A1 (en) 2001-12-07 2003-08-07 Olli Tuominen Copolymer coating for a hydrophobic membrane
AU2003213758A1 (en) 2002-03-14 2003-09-29 Fenwal, Inc. Compound removal device
EP1507557A4 (en) 2002-04-23 2006-06-14 Meir Strahilevitz METHODS AND DEVICES FOR TARGETING A SITE IN A MAMMAL AND DETERMINING CHEMICAL SPECIES FROM A MAMMAL
US7488309B2 (en) 2002-07-03 2009-02-10 Bioanalytical Systems, Inc. Device and method for drug delivery to animals
AU2003242509A1 (en) 2002-07-11 2004-02-02 Upfront Chromatography A/S An extracorporeal stabilised expanded bed adsorption method for the treatment of sepsis
JP4587954B2 (ja) 2002-07-24 2010-11-24 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド タンパク質相互作用相違マッピング
US20040182783A1 (en) 2003-03-17 2004-09-23 Walker Kimberly A. Filter and concentrator device for treatment of blood
US7207964B2 (en) * 2003-03-17 2007-04-24 Hemavation, Llc Apparatus and method for down-regulating immune system mediators in blood
DK2103694T3 (da) 2003-08-15 2011-09-12 Univ South Florida Materialer og fremgangsmåder til indfangning af patogener og fjernelse af aurintricarboxylsyre fra en prøve
US7399400B2 (en) 2003-09-30 2008-07-15 Nano-Proprietary, Inc. Nanobiosensor and carbon nanotube thin film transistors
CA2546222A1 (en) 2003-11-19 2005-06-09 Chiron Corporation Methods and reagents for treating, preventing and diagnosing bunyavirus infection
US7540958B2 (en) 2004-03-08 2009-06-02 Gambro Lundia Ab Device for controlling blood circulation for a single needle circuit
WO2006093524A2 (en) 2004-07-16 2006-09-08 The General Hospital Corporation Antigen-carbohydrate conjugates
EP1790365B1 (en) 2004-07-23 2015-11-18 Kaneka Corporation Direct hemoperfusion adsorber packed with adsorbent having water-insoluble microparticles removed therefrom, and method of obtaining direct hemoperfusion adsorber packed with adsorbent having water-insoluble microparticles removed therefrom
DE102004037475A1 (de) 2004-07-30 2006-03-23 Heinrich, Hans-Werner, Prof. Dr. Filtersystem zur membrangetrennten, adsorptiven Behandlung partikelhaltiger Flüssigkeiten
DE112005001901T5 (de) 2004-08-04 2007-07-12 Aspira Biosystems Inc., Incline Village Einfangen und entfernen von Biomolekülen aus Körperflüssigkeiten unter Verwendung von partiellen molekularen Abdrücken
WO2006025371A1 (ja) 2004-08-30 2006-03-09 Kaneka Corporation 顆粒球吸着材
US8445293B2 (en) 2005-02-09 2013-05-21 Rapid Pathogen Screening, Inc. Method to increase specificity and/or accuracy of lateral flow immunoassays
GB0509433D0 (en) 2005-05-09 2005-06-15 Uni For Milj Og Biovitenskap Method
EP1899450A4 (en) 2005-06-24 2010-03-24 Univ Texas SYSTEMS AND METHODS INCLUDING INCLUDED CASSETTES WITH DEFINITION SYSTEMS AND LIQUIDITY SUPPLY SYSTEMS
US20100239673A1 (en) 2005-08-01 2010-09-23 Linhardt Robert J Blood compatible nanomaterials and methods of making and using the same
EP1951394A4 (en) 2005-11-21 2011-01-19 Ge Healthcare Bio Sciences Ab CHROMATOGRAPHY PROCEDURES USING HALF-SYNTHETIC HEPARIN LIGANDS
MX344592B (es) 2005-12-13 2016-12-20 Exthera Medical Corp Metodo para eliminar extracorporalmente de la sangre un microbio patogeno, una celula inflamatoria o una proteina inflamatoria.
KR101423938B1 (ko) 2005-12-21 2014-08-06 메소 스케일 테크놀러지즈, 엘엘시 분석 장치, 방법 및 시약
CA2643140C (en) 2006-02-22 2014-12-09 Henry Ford Health System System and method for delivery of regional citrate anticoagulation to extracorporeal blood circuits
WO2007146162A2 (en) 2006-06-08 2007-12-21 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Devices, systems and methods for reducing the concentration of a chemical entity in fluids
CN101460206B (zh) 2006-06-16 2012-09-26 泰尔茂株式会社 血液处理过滤器及血液处理回路
FR2902670B1 (fr) 2006-06-22 2009-04-24 Gambro Lundia Ab Utilisation d'une suspension pour traiter un support a usage medical, support a usage medical, echangeur et dispositif d'adsorption comprenant le support
WO2008147382A1 (en) 2006-09-27 2008-12-04 Micronics, Inc. Integrated microfluidic assay devices and methods
WO2008051762A2 (en) 2006-10-26 2008-05-02 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
GB0702183D0 (en) 2007-02-05 2007-03-14 Iti Scotland Ltd Pathogen binding
WO2008128251A1 (en) 2007-04-17 2008-10-23 The Children's Hospital Of Philadelphia Humanized viral vectors and methods of use thereof
US20100145317A1 (en) 2007-04-19 2010-06-10 Morris Laster Device system and method for monitoring and controlling blood analyte levels
WO2008155683A1 (en) 2007-06-18 2008-12-24 Firmenich Sa Malodor counteracting compositions and method for their use
AU2008265838A1 (en) * 2007-06-18 2008-12-24 Exthera Medical Llc Device and method for restoration of the condition of blood
JP4226050B1 (ja) 2007-09-12 2009-02-18 株式会社Ｒｅｉメディカル 体液浄化処理用吸着カラム
US20110183398A1 (en) 2007-12-31 2011-07-28 3M Innovative Properties Microorganism-capturing compositions and methods
US11051733B2 (en) 2008-01-18 2021-07-06 Wake Forest University Health Sciences Isolating and purifying cells for therapy
EP2087916A1 (en) 2008-02-11 2009-08-12 ICinnovation BV Electrosorption device for the purification of blood and other fluids
CN101632686A (zh) 2008-04-04 2010-01-27 马斯特里赫特大学 糖胺聚糖用于修复糖萼的用途
AU2009263046B2 (en) 2008-06-23 2014-07-24 Temasek Polytechnic A flow system of a dialysis device and a portable dialysis device
US20100021622A1 (en) 2008-07-24 2010-01-28 National Chiao Tung University Apparatus and method for forming multilayer polymer thin film
US20100040546A1 (en) 2008-08-13 2010-02-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Biological targeting compositions and methods of using the same
CN102186880A (zh) 2008-09-10 2011-09-14 Ith免疫治疗控股股份公司 炎症的治疗
US8310415B2 (en) 2008-09-30 2012-11-13 Animas Corporation Medical devices using bistable displays
US8430831B2 (en) 2009-02-25 2013-04-30 The Invention Science Fund I, Llc Device, system, and method for controllably reducing inflammatory mediators in a subject
US8801922B2 (en) 2009-06-24 2014-08-12 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Dialysis system
WO2011014863A2 (en) 2009-07-31 2011-02-03 Alt Eckhard U Prophylaxis against cancer metastasis
EP2509604B1 (en) * 2009-12-01 2021-03-17 ExThera Medical Corporation Device for removing cytokines from blood with surface immobilized polysaccharides
US8366649B2 (en) 2009-12-09 2013-02-05 Araz Ibragimov Manually operated disposable single-needle circuit for extracorporeal treatment of blood
AU2011215942B8 (en) 2010-02-09 2014-02-13 Exthera Medical Corporation Removal of virulence factors through extracorporeal therapy
WO2011133287A1 (en) 2010-04-19 2011-10-27 The Trustees Of Columbia University In The City Of New York Portable blood filtration devices, systems, and methods
EP2627369B1 (en) * 2010-10-15 2022-01-12 SeaStar Medical, Inc. Cytopheresic cartridge and use thereof
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
US20130131423A1 (en) * 2011-04-12 2013-05-23 Tianxin Wang Methods to detect and treat diseases
CN103857421B (zh) 2011-06-13 2017-09-22 Tla指标免疫疗法公司 治疗癌症的方法和在其中使用的结合试剂
SG10201608671SA (en) 2011-07-18 2016-12-29 Harvard College Engineered Microbe-Targeting Molecules and Uses Thereof
EP2556849A1 (en) 2011-08-08 2013-02-13 Gambro Lundia AB Separation material
EP2861273B1 (en) 2012-06-13 2017-08-23 ExThera Medical Corporation Use of heparin and carbohydrates to treat cancer
US9717841B2 (en) 2012-09-11 2017-08-01 Gary L. McNeil Closed-circuit device and methods for isolation, modification, and re-administration of specific constituents from a biological fluid source
WO2014085713A1 (en) 2012-11-30 2014-06-05 The Methodist Hospital Research Institute Methods and compositions for detecting tuberculosis
HK1216625A1 (zh) 2013-06-24 2016-11-25 Exthera Medical Corporation 含有塗覆甘露糖的基質的血液過濾系統
EP3049405A4 (en) 2013-09-26 2017-03-08 Pharmakea Inc. Autotaxin inhibitor compounds
AU2014346668C1 (en) 2013-11-08 2018-04-26 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
EP3134146B1 (en) 2014-04-24 2024-12-25 ExThera Medical Corporation Method for removing bacteria from blood using high flow rate
CN106714669B (zh) 2014-09-22 2021-05-14 艾克塞拉医疗公司 可穿戴的血液灌流装置
EP4029539A1 (en) 2015-04-07 2022-07-20 NxStage Medical Inc. Blood treatment device priming devices, methods, and systems
WO2017001357A1 (en) 2015-06-29 2017-01-05 Gambro Lundia Ab Extracorporeal blood treatment apparatus for single-needle treatments
EP3422943A4 (en) 2016-03-02 2019-10-16 ExThera Medical Corporation METHOD OF TREATING DRUG ENTRIES
US9694344B2 (en) 2016-05-02 2017-07-04 LiSo Plastics, L.L.C. Multilayer polymeric membrane and process
CN206345699U (zh) 2016-09-13 2017-07-21 南京佳乐净膜科技有限公司 一种具有长效反冲洗功能的多级复合超微滤膜滤芯
US20200023001A1 (en) 2018-07-20 2020-01-23 Northeastern University GlycoFix (Structurally And Functionally Repaired Endothelial Glycocalyx)
EP3969014A4 (en) 2019-05-16 2023-01-25 ExThera Medical Corporation METHODS OF MODULATION OF ENDOTHELIAL GLYCOCALYX STRUCTURE
WO2021119195A1 (en) 2019-12-12 2021-06-17 Chawla Lakhmir Singh Extracorporeal blood treatment systems and methods employing batch processing
WO2021119197A1 (en) 2019-12-12 2021-06-17 Chawla Lakhmir Singh Syringe-based manual extracorporeal blood treatment systems and methods employing batch processing
MX2023010736A (es) 2021-04-06 2023-09-20 Exthera Medical Corp Medios de filtracion.

Also Published As

Publication number Publication date
ES2625351T1 (es) 2017-07-19
AU2020200029A1 (en) 2020-01-30
EP3134146A1 (en) 2017-03-01
ES2625351T3 (en) 2025-04-07
CN106255520A (zh) 2016-12-21
BR112016024569A2 (pt) 2017-08-15
WO2015164198A1 (en) 2015-10-29
AU2015250107A1 (en) 2016-11-17
BR112016024569B1 (pt) 2023-01-03
AU2020200029B2 (en) 2022-07-28
US11844895B2 (en) 2023-12-19
US20200171233A1 (en) 2020-06-04
CA2946294A1 (en) 2015-10-29
CA2946294C (en) 2023-03-21
EP3134146A4 (en) 2018-01-10
KR20170020749A (ko) 2017-02-24
DE15782250T1 (de) 2017-08-10
CN106255520B (zh) 2022-08-12
BR112016024569A8 (pt) 2021-06-01
JP2021045573A (ja) 2021-03-25
JP2022125040A (ja) 2022-08-26
JP7184864B2 (ja) 2022-12-06
US20170035956A1 (en) 2017-02-09
EP3134146B1 (en) 2024-12-25
JP2017513636A (ja) 2017-06-01

Similar Documents

Publication Publication Date Title
MX2016013873A (es) Metodo para eliminar bacterias de la sangre usando alta velocidad de flujo.
MX2024009339A (es) Biomarcadores utiles en el diagnostico de infecciones bacterianas y virales.
AU2015339284A8 (en) Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
IL262603B (en) Devices, systems and methods for treating medical devices that have passages with ozone gas
EP4414005A3 (en) Apparatus for extracorporeal treatment of blood
PH12015501787A1 (en) Systems and methods for ocular surgery
PT3407945T (pt) Método para medir características de fluxo num inalador, inalador e sistema
PH12018500887A1 (en) Anti-htra1 antibodies and methods of use thereof
EP3035612A4 (en) Method for making flow table multiple levels, and multi-level flow table processing method and device
MY173304A (en) Induction of immune tolerance using methotrexate
EP3127564A4 (en) Blood purification device and fluid replacement/priming method for blood purification device
EP3277431A4 (en) Double filter with pass-through and method for dynamically compensating for the inlet fluid contamination
EP3294386A4 (en) SYSTEMS AND METHOD FOR IMPROVED BUBBLE DETECTION FOR INFUSION PUMPS
MX2017014738A (es) Solventes para remover mercurio.
MX2015012236A (es) Sistema de valvula de purga del canister.
EP3332375A4 (en) SYSTEM AND METHOD FOR IDENTIFYING THE INTERESTS OF A USER THROUGH A SOCIAL MEDIA
MY190476A (en) Steady state fluid flow verification for sample takeoff
MX2018002499A (es) Sistemas y metodos para conservacion de muestra de sangre y separacion de hematocritos.
EP3487572A4 (en) DEVICE AND METHOD FOR DELIVERING LIQUIDS AND / OR GASES TO THE LUNG
IL254285A0 (en) Systems and methods for controlling electric fields in liquids, gases and bacteria
PL3765126T3 (pl) Urządzenie, zestaw i sposób wytwarzania medycznie dostarczalnego dożylnego roztworu soli fizjologicznej
EP3194945A4 (en) Apparatuses, methods, systems, and computer-readable media for fluid potential artifact correction in reagent delivery systems
ZA201800475B (en) Regenerated media useful in the treatment of fermented liquids
SG11202104595PA (en) Fluid pump assemblies and kits, and related methods
EP3848116A4 (en) COBAL ION ADSORPENT, PROCESS FOR THE PRODUCTION THEREOF AND TREATMENT APPARATUS FOR COBAL ION CONTAINING LIQUID