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MX2016013693A - Crema transdermica. - Google Patents

Crema transdermica.

Info

Publication number
MX2016013693A
MX2016013693A MX2016013693A MX2016013693A MX2016013693A MX 2016013693 A MX2016013693 A MX 2016013693A MX 2016013693 A MX2016013693 A MX 2016013693A MX 2016013693 A MX2016013693 A MX 2016013693A MX 2016013693 A MX2016013693 A MX 2016013693A
Authority
MX
Mexico
Prior art keywords
pharmaceutical compositions
progesterone
limonene
medium
transdermal
Prior art date
Application number
MX2016013693A
Other languages
English (en)
Inventor
Persicaner Peter
Thorsteinsson Thorsteinn
Ghanta Ajay
Amadio Julia
Shadiack Annette
Winneker Richard
Legassie Jason
Original Assignee
Therapeuticsmd Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therapeuticsmd Inc filed Critical Therapeuticsmd Inc
Publication of MX2016013693A publication Critical patent/MX2016013693A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta descripción se refiere a composiciones farmacéuticas transdérmicas que contienen progesterona en una combinación con uno o más agentes solubilizantes y agentes mejoradores de penetración, en donde las composiciones farmacéuticas se formulan como cremas para administración tópica. En algunas modalidades, las composiciones farmacéuticas transdérmicas contienen progesterona, un aceite de cadena media, y d-limoneno . En algunas modalidades, las composiciones farmacéuticas transdérmicas contienen progesterona, un aceite de cadena media, un agente mejorador de penetración (por ejemplo, propilen glicol, un éster de ácido graso de propilen glicol, un éter de glicol), y opcionalmente d-limoneno. En ciertas modalidades, las composiciones farmacéuticas incluyen además estradiol. También se describen métodos para tratar condiciones asociadas con deficiencia hormonal en un sujeto.
MX2016013693A 2014-07-29 2015-07-29 Crema transdermica. MX2016013693A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462030540P 2014-07-29 2014-07-29
US201562152674P 2015-04-24 2015-04-24
PCT/US2015/042621 WO2016018993A1 (en) 2014-07-29 2015-07-29 Transdermal cream

Publications (1)

Publication Number Publication Date
MX2016013693A true MX2016013693A (es) 2017-10-31

Family

ID=55178912

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016013693A MX2016013693A (es) 2014-07-29 2015-07-29 Crema transdermica.

Country Status (11)

Country Link
US (2) US10098894B2 (es)
EP (1) EP3174542A4 (es)
JP (1) JP2017523138A (es)
KR (1) KR20170040209A (es)
AU (1) AU2015296609A1 (es)
BR (1) BR112016029338A2 (es)
CA (1) CA2951284A1 (es)
IL (1) IL248984A0 (es)
MX (1) MX2016013693A (es)
RU (1) RU2016141135A (es)
WO (1) WO2016018993A1 (es)

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US20200038392A1 (en) * 2018-08-03 2020-02-06 Aldeyra Therapeutics, Inc. Topical compositions and methods of preparation and use
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US12098132B2 (en) 2019-05-02 2024-09-24 Aldeyra Therapeutics, Inc. Process for preparation of aldehyde scavenger and intermediates
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