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MX2015017959A - Composiciones y metodos para inmunoterapia. - Google Patents

Composiciones y metodos para inmunoterapia.

Info

Publication number
MX2015017959A
MX2015017959A MX2015017959A MX2015017959A MX2015017959A MX 2015017959 A MX2015017959 A MX 2015017959A MX 2015017959 A MX2015017959 A MX 2015017959A MX 2015017959 A MX2015017959 A MX 2015017959A MX 2015017959 A MX2015017959 A MX 2015017959A
Authority
MX
Mexico
Prior art keywords
compositions
immunotherapy
methods
antigen
lymphocytes
Prior art date
Application number
MX2015017959A
Other languages
English (en)
Other versions
MX375994B (es
Inventor
David Jones Timothy
Joseph Carr Francis
Mccreedy Bruce
Original Assignee
Neximmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neximmune Inc filed Critical Neximmune Inc
Publication of MX2015017959A publication Critical patent/MX2015017959A/es
Publication of MX375994B publication Critical patent/MX375994B/es

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
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    • A61K47/6931—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
    • A61K47/6935—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being obtained otherwise than by reactions involving carbon to carbon unsaturated bonds, e.g. polyesters, polyamides or polyglycerol
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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  • Veterinary Medicine (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención provee composiciones y métodos de inmunoterapia que incluyen composiciones farmacéuticas estables en condiciones de almacenamiento para la inducción de linfocitos T específicos para un antígeno. Dichas composiciones son utilizadas como componentes en una cédula que presenta antígenos artificiales (aAPC) con el fin de proporcionarle a un paciente complejos de presentación de una molécula de coestimulación de linfocitos T y/o un antígeno (por ejemplo, un antígeno tumoral).
MX2015017959A 2013-06-24 2014-06-23 Composicion farmaceutica que comprende particulas de plga-peg. MX375994B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361838547P 2013-06-24 2013-06-24
US201461948916P 2014-03-06 2014-03-06
PCT/US2014/043629 WO2014209868A1 (en) 2013-06-24 2014-06-23 Compositions and methods for immunotherapy

Publications (2)

Publication Number Publication Date
MX2015017959A true MX2015017959A (es) 2018-03-01
MX375994B MX375994B (es) 2025-03-07

Family

ID=52142591

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015017959A MX375994B (es) 2013-06-24 2014-06-23 Composicion farmaceutica que comprende particulas de plga-peg.

Country Status (13)

Country Link
US (3) US20160129133A1 (es)
EP (2) EP3995145B1 (es)
JP (1) JP6566938B2 (es)
KR (2) KR20160022370A (es)
CN (2) CN113797332B (es)
AU (1) AU2014302784B2 (es)
BR (1) BR112015032277B1 (es)
CA (1) CA2916465C (es)
ES (1) ES2902413T3 (es)
IL (2) IL243235B (es)
MX (1) MX375994B (es)
SG (2) SG10201710737VA (es)
WO (1) WO2014209868A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3970748B1 (en) 2014-12-24 2024-07-24 NexImmune, Inc. Nanoparticle compositions and methods for immunotherapy
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