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MX2011008553A - Compuestos como antagonistas de bradiquinina b1. - Google Patents

Compuestos como antagonistas de bradiquinina b1.

Info

Publication number
MX2011008553A
MX2011008553A MX2011008553A MX2011008553A MX2011008553A MX 2011008553 A MX2011008553 A MX 2011008553A MX 2011008553 A MX2011008553 A MX 2011008553A MX 2011008553 A MX2011008553 A MX 2011008553A MX 2011008553 A MX2011008553 A MX 2011008553A
Authority
MX
Mexico
Prior art keywords
compounds
bradykinin
antagonists
production
salts
Prior art date
Application number
MX2011008553A
Other languages
English (en)
Inventor
Henri Doods
Norbert Hauel
Dieter Wiedenmayer
Henning Priepke
Ingo Konetzki
Annette Schuler-Metz
Juergen Mack
Rainer Walter
Angelo Ceci
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2011008553A publication Critical patent/MX2011008553A/es

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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

Objeto de la presente invención son los compuestos de la fórmula general I (ver fórmula (I)) en la que n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 y X se definen como se describe posteriormente, sus enantiómeros, sus diastereoisómeros, sus mezclas y sus sales, en especial sus sales fisiológicamente tolerables con ácidos o bases orgánicos o inorgánicos, que presentan valiosas propiedades, su preparación, los medicamentos que contienen los compuestos farmacológicamente eficaces, su preparación y su uso.
MX2011008553A 2009-02-26 2010-02-23 Compuestos como antagonistas de bradiquinina b1. MX2011008553A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09153778 2009-02-26
PCT/EP2010/052232 WO2010097372A1 (de) 2009-02-26 2010-02-23 Verbindungen als bradykinin-b1-antagonisten

Publications (1)

Publication Number Publication Date
MX2011008553A true MX2011008553A (es) 2011-09-09

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CO6430425A2 (es) 2012-04-30
HRP20130666T1 (en) 2013-10-11
MA33238B1 (fr) 2012-05-02
TW201041870A (en) 2010-12-01
JP2012518672A (ja) 2012-08-16
PL2401256T3 (pl) 2013-09-30
GEP20135933B (en) 2013-10-10
AP2011005808A0 (en) 2011-08-31
UY32463A (es) 2010-09-30
ECSP11011304A (es) 2011-10-31
RS53710B2 (sr) 2018-07-31
ME01526B (me) 2014-04-20
EA201201167A1 (ru) 2013-04-30
PT2401256E (pt) 2013-05-13
EA201101209A1 (ru) 2012-04-30
MY153941A (en) 2015-04-15
TN2011000438A1 (en) 2013-03-27
CN102414177A (zh) 2012-04-11
EA023437B1 (ru) 2016-06-30
KR101660357B1 (ko) 2016-09-27
CN102414177B (zh) 2014-07-02
IL214129A0 (en) 2011-08-31
EP2401256A1 (de) 2012-01-04
RS52801B (en) 2013-10-31
CL2011002076A1 (es) 2012-02-17
SI2401256T1 (sl) 2013-08-30
WO2010097372A1 (de) 2010-09-02
ECSP12012161A (es) 2012-10-30
PH12012501678A1 (en) 2019-07-10
ES2421630T3 (es) 2013-09-04
TN2012000417A1 (en) 2014-01-30
CY1114130T1 (el) 2016-07-27
US20100240669A1 (en) 2010-09-23
NZ594674A (en) 2013-12-20
US20130131075A1 (en) 2013-05-23
DK2401256T3 (da) 2013-06-03
BRPI1008779A2 (pt) 2020-12-22
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PE20120360A1 (es) 2012-04-14
JP5629274B2 (ja) 2014-11-19
UA105923C2 (uk) 2014-07-10
AU2010217606B2 (en) 2016-07-07
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KR20110120913A (ko) 2011-11-04
EA024656B1 (ru) 2016-10-31
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CA2759126C (en) 2017-08-22
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