[go: up one dir, main page]

MX2010008591A - Dispositivos, sistemas y metodos de separacion de fluidos. - Google Patents

Dispositivos, sistemas y metodos de separacion de fluidos.

Info

Publication number
MX2010008591A
MX2010008591A MX2010008591A MX2010008591A MX2010008591A MX 2010008591 A MX2010008591 A MX 2010008591A MX 2010008591 A MX2010008591 A MX 2010008591A MX 2010008591 A MX2010008591 A MX 2010008591A MX 2010008591 A MX2010008591 A MX 2010008591A
Authority
MX
Mexico
Prior art keywords
blood
plasma
separation device
patient
membraneless separation
Prior art date
Application number
MX2010008591A
Other languages
English (en)
Inventor
Edward F Leonard
Ilan K Reich
Stanley Cortell
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of MX2010008591A publication Critical patent/MX2010008591A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3482Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate by filtrating the filtrate using another cross-flow filter, e.g. a membrane filter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/11Laminar flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Un dispositivo de separación sin membrana se puede aplicar en una diversidad de tratamientos, tal como la ultrafiltración de sangre para un paciente con una enfermedad renal en la etapa final. Un dispositivo de ultrafiltración puede incluir un dispositivo de separación sin membrana el cual separa el flujo de sangre entrante en un flujo de plasma sustancialmente libre de cuerpos citoplásmicos y la fracción remanente y una segunda etapa libre de dializado la cual separa selectivamente el exceso de fluido, toxinas y otras sustancias del flujo de plasma y regresa el plasma procesado al dispositivo de separación sin membrana. Un procedimiento de tratamiento puede incluir la ultrafiltración de sangre de un paciente utilizando el dispositivo de ultrafiltración y al realizar un tratamiento secundario sobre la sangre del paciente a una frecuencia reducida en comparación con el ultrafiltrado. El dispositivo de separación sin membrana también se puede aplicar al tratamiento, análisis y/o intercambio del plasma desde la sangre o se puede combinar con dializadores convencionales para realizar diálisis en una fracción de plasma libre de cuerpos citoplásmicos.
MX2010008591A 2008-02-04 2009-02-04 Dispositivos, sistemas y metodos de separacion de fluidos. MX2010008591A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US686608P 2008-02-04 2008-02-04
US7395108P 2008-06-19 2008-06-19
PCT/US2009/033111 WO2009100154A1 (en) 2008-02-04 2009-02-04 Fluid separation devices, systems and methods

Publications (1)

Publication Number Publication Date
MX2010008591A true MX2010008591A (es) 2010-08-30

Family

ID=40952445

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010008591A MX2010008591A (es) 2008-02-04 2009-02-04 Dispositivos, sistemas y metodos de separacion de fluidos.

Country Status (9)

Country Link
US (1) US8496606B2 (es)
EP (1) EP2249899A4 (es)
JP (1) JP2011514182A (es)
CN (1) CN102065926A (es)
AU (1) AU2009212396A1 (es)
BR (1) BRPI0907473A2 (es)
CA (1) CA2714594A1 (es)
MX (1) MX2010008591A (es)
WO (1) WO2009100154A1 (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4821466B2 (ja) * 2006-07-03 2011-11-24 富士ゼロックス株式会社 液滴吐出ヘッド
WO2009039378A2 (en) * 2007-09-19 2009-03-26 The Charles Stark Draper Laboratory, Inc. Microfluidic structures for biomedical applications
WO2009079383A1 (en) * 2007-12-14 2009-06-25 The Trustees Of Columbia University In The City Of New York Systems, methods, and devices for blood treatment
WO2009094236A2 (en) * 2008-01-11 2009-07-30 California Institute Of Technology Autonomous electrochemical actuation of microfluidic circuits
US20090234332A1 (en) * 2008-03-17 2009-09-17 The Charles Stark Draper Laboratory, Inc Artificial microvascular device and methods for manufacturing and using the same
KR101691073B1 (ko) 2008-09-24 2016-12-29 리플리겐 코포레이션 흐름 여과를 교번하기 위한 스크린 필터 모듈
US10751464B2 (en) * 2009-08-25 2020-08-25 Nanoshell Company, Llc Therapeutic retrieval of targets in biological fluids
US11285494B2 (en) 2009-08-25 2022-03-29 Nanoshell Company, Llc Method and apparatus for continuous removal of sub-micron sized particles in a closed loop liquid flow system
US10099227B2 (en) 2009-08-25 2018-10-16 Nanoshell Company, Llc Method and apparatus for continuous removal of sub-micron sized particles in a closed loop liquid flow system
US20110082563A1 (en) * 2009-10-05 2011-04-07 The Charles Stark Draper Laboratory, Inc. Microscale multiple-fluid-stream bioreactor for cell culture
WO2011044116A2 (en) * 2009-10-05 2011-04-14 The Charles Stark Draper Laboratory, Inc. Three-dimensional microfluidic platforms and methods of use and manufacture thereof
WO2011133287A1 (en) * 2010-04-19 2011-10-27 The Trustees Of Columbia University In The City Of New York Portable blood filtration devices, systems, and methods
PL2590696T3 (pl) 2010-07-05 2017-08-31 Gambro Lundia Ab Ambulatoryjne urządzenie do ultrafiltracji, powiązane sposoby i produkt w postaci programu komputerowego
KR101227453B1 (ko) * 2010-07-29 2013-01-29 서강대학교산학협력단 인공 신단위 장치
EP3492574A3 (en) * 2010-08-25 2019-09-04 Refine Technology, LLC Fluid filtration systems
US9446354B2 (en) 2010-08-25 2016-09-20 Repligen Corporation Device, system and process for modification or concentration of cell-depleted fluid
CN107315086B (zh) 2011-06-29 2019-09-10 中央研究院 使用表面涂层对生物物质的捕获、纯化和释放
JP5834559B2 (ja) * 2011-07-12 2015-12-24 コニカミノルタ株式会社 目的細胞の検査方法
DE112014001309T5 (de) * 2013-03-13 2016-01-07 Nxstage Medical, Inc. Single-Pass-Dialyse in Kombination mit Multiple-Pass-Albumin-Dialyse
US9895109B2 (en) * 2013-03-20 2018-02-20 Gambro Lundia Ab Monitoring of cardiac arrest in a patient connected to an extracorporeal blood processing apparatus
EP3038673B1 (en) * 2013-08-30 2018-10-10 Kpr U.S., Llc Enteral feeding pump with pump set flushing and flow compensation
TW201623605A (zh) 2014-04-01 2016-07-01 中央研究院 用於癌症診斷及預後之方法及系統
KR101984559B1 (ko) * 2014-08-20 2019-05-31 스템 셀 에스.알.엘. 대상물의 분류를 위한 장치 및 분류 방법
CN105381824B (zh) 2014-08-26 2019-04-23 中央研究院 收集器架构布局设计
US10220132B2 (en) * 2014-12-19 2019-03-05 Fenwal, Inc. Biological fluid flow control apparatus and method
US10737012B2 (en) 2015-03-31 2020-08-11 Biomet Biologics, Inc. Cell washing using acoustic waves
US9855382B2 (en) * 2015-03-31 2018-01-02 Biomet Biologics, Llc Cell washing device using standing acoustic waves and a phantom material
JP6713730B2 (ja) 2015-05-20 2020-06-24 シスメックス株式会社 細胞検出装置および細胞検出方法
US9814822B2 (en) 2015-08-27 2017-11-14 Fresenius Medical Care Holdings, Inc. Plasma generation with dialysis systems
US10107726B2 (en) 2016-03-16 2018-10-23 Cellmax, Ltd. Collection of suspended cells using a transferable membrane
CN106092848B (zh) * 2016-03-22 2018-07-06 威海威高血液净化制品有限公司 透析器超滤性能测试液
EP3414011B1 (en) * 2016-04-28 2023-01-04 Hewlett-Packard Development Company, L.P. Microfluidic filtering
US10456515B2 (en) 2016-06-06 2019-10-29 The Trustees Of Columbia University In The City Of New York Wearable ultrafiltration devices methods and systems
MA39440A1 (fr) * 2016-11-07 2018-05-31 Univ Hassan Ii De Casablanca Dispositif portable d'ultrafiltration
JP6698558B2 (ja) * 2017-01-11 2020-05-27 東レエンジニアリング株式会社 成分濃度検出システム
CN110462367B (zh) * 2017-02-17 2023-06-27 斯泰特皮尔股份公司 过滤装置
WO2018187745A1 (en) * 2017-04-06 2018-10-11 Sri International Modular systems for performing multistep chemical reactions, and methods of using same
US11524295B2 (en) 2017-05-19 2022-12-13 Aipore Inc. Channel device and method for concentrating fine particles
US11027239B2 (en) * 2017-10-05 2021-06-08 Global Life Sciences Solutions Usa Llc Systems and methods for utilizing crossflow filtration for cell enrichment
CN108211032B (zh) 2018-02-01 2023-11-17 南方医科大学珠江医院 组合型生物人工肝支持系统
WO2020033021A1 (en) * 2018-08-08 2020-02-13 The Trustees Of Columbia University In The City Of New York Wearable ultrafiltration devices methods and systems
CN114269406A (zh) * 2019-04-05 2022-04-01 奇德尼实验室公司 用于肾脏治疗的吸着剂
US20230108155A1 (en) * 2020-02-19 2023-04-06 Qidni Labs Inc. Portable and wearable drug delivery system
US20240269357A1 (en) * 2020-08-19 2024-08-15 Shanghai Xinguang Bio-Pharmaceutical Ltd Fluid treatment method and fluid treatment device
CN116568345A (zh) * 2020-11-13 2023-08-08 费森尤斯医疗保健控股公司 增加红细胞计数的技术
CN113855886B (zh) * 2021-10-20 2024-11-08 中国科学技术大学 一种无膜透析微流控制芯片
CN114699581B (zh) * 2022-03-31 2025-03-07 中国科学技术大学 具有并行结构的无膜透析微流控芯片
US12303630B2 (en) 2022-07-25 2025-05-20 William M. Gosney Apparatus utilizing electric field for processing of blood to neutralize pathogen cells therein
US12138377B2 (en) * 2022-07-25 2024-11-12 William M. Gosney Apparatus for processing of blood to neutralize pathogen cells therein
US12133948B2 (en) 2022-07-25 2024-11-05 William M. Gosney Apparatus utilizing venting for processing of blood to remove pathogen cells therein
WO2024105681A1 (en) * 2022-11-19 2024-05-23 Ykrita Lifesciences Private Limited Extracorporeal bioengineered dual-cell liver regeneration system (ebdlr) and bio purifier therefor

Family Cites Families (213)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2885782A (en) * 1956-06-11 1959-05-12 James R Groves Vacuum ejector for dental debris
US3388803A (en) 1965-04-16 1968-06-18 Applied Biolog Sciences Lab In Wearable dialysis apparatus
US3799873A (en) * 1968-04-19 1974-03-26 Hydronautics Artificial kidney
US3506126A (en) * 1968-05-03 1970-04-14 Milton Roy Co Closed recirculating hemodialysis system
US3619423A (en) 1970-04-20 1971-11-09 Us Health Education & Welfare Cascade dialysis apparatus and method
DE2239254C2 (de) 1970-12-30 1983-08-04 Organon Teknika Corp., Oklahoma City, Okla. "Säule zur Regenerierung einer zirkulierenden Dialysatlösung und Verwendung dieser Säule".
BE788759A (fr) 1971-09-14 1973-01-02 Atomic Energy Commission Dialyseur compact pour la dialyse du sang et autres applications
BE792314A (fr) * 1971-12-06 1973-06-05 Rhone Poulenc Sa Perfectionnement aux reins artificiels
US3994799A (en) 1973-04-17 1976-11-30 Yao Shang J Blood and tissue detoxification apparatus
US3884808A (en) * 1973-06-20 1975-05-20 Res Dev Systems Inc Wearable, self-regenerating dialysis appliance
DE2444524A1 (de) * 1974-09-18 1976-04-08 Oeser Henning Dr Verfahren und vorrichtung zur ausfaellung von human-blutplasma-bestandteilen
US4083786A (en) * 1975-03-20 1978-04-11 Asahi Kasei Kogyo Kabushiki Kaisha Apparatus for treating ascites
US4153554A (en) * 1977-02-22 1979-05-08 American Micro-Bionics Corp. Apparatus for use in artificial kidney system
US4094775A (en) 1977-02-28 1978-06-13 California Institute Of Technology Dialysis system
FR2385406A1 (fr) 1977-03-28 1978-10-27 Akzo Nv Rein artificiel
US4243775A (en) * 1978-11-13 1981-01-06 American Cyanamid Company Synthetic polyester surgical articles
US4300565A (en) 1977-05-23 1981-11-17 American Cyanamid Company Synthetic polyester surgical articles
US4137921A (en) * 1977-06-24 1979-02-06 Ethicon, Inc. Addition copolymers of lactide and glycolide and method of preparation
US4166800A (en) 1977-08-25 1979-09-04 Sandoz, Inc. Processes for preparation of microspheres
US4181983A (en) * 1977-08-29 1980-01-08 Kulkarni R K Assimilable hydrophilic prosthesis
DE2843963A1 (de) 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
IT1174707B (it) * 1978-05-03 1987-07-01 Bonomini Vittorio Rene artificiale portatile per dialisi
US4390519A (en) 1978-05-19 1983-06-28 Sawyer Philip Nicholas Bandage with hemostatic agent and methods for preparing and employing the same
US4212742A (en) 1978-05-25 1980-07-15 United States Of America Filtration apparatus for separating blood cell-containing liquid suspensions
DE2838414C2 (de) * 1978-09-02 1984-10-31 Fresenius AG, 6380 Bad Homburg Vorrichtung zur Hämodialyse und zum Entziehen von Ultrafiltrat
FR2439003A1 (fr) 1978-10-20 1980-05-16 Anvar Nouvelles pieces d'osteosynthese, leur preparation et leur application
US4247393A (en) * 1979-01-11 1981-01-27 Wallace Richard A Hemodialysis assist device
JPS6032505B2 (ja) 1979-03-19 1985-07-29 株式会社吉野工業所 液体噴霧器
US4321192A (en) * 1980-01-10 1982-03-23 Ionics Incorporated Fractionation of protein mixtures by salt addition followed by dialysis treatment
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US5366734A (en) 1981-02-16 1994-11-22 Zeneca Limited Continuous release pharmaceutical compositions
US4585797A (en) * 1981-04-13 1986-04-29 Seton Company Cosmetic and pharmaceutical sheet material containing polypeptides
US4431019A (en) * 1981-06-25 1984-02-14 Baxter Travenol Laboratories, Inc. Fluid flow control device
US4394370A (en) 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4443333A (en) * 1981-09-24 1984-04-17 Mahurkar Sakharam D Portable dialysis system and pump therefor
US4409332A (en) 1982-01-12 1983-10-11 Jefferies Steven R Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same
US4538603A (en) 1982-04-22 1985-09-03 E. R. Squibb & Sons, Inc. Dressings, granules, and their use in treating wounds
US4539981A (en) 1982-11-08 1985-09-10 Johnson & Johnson Products, Inc. Absorbable bone fixation device
US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
US4765899A (en) 1983-10-11 1988-08-23 E. I. Du Pont De Nemours And Company Apparatus for continuous separation of leukocyte/platelet-enriched fraction from whole blood
US4818542A (en) * 1983-11-14 1989-04-04 The University Of Kentucky Research Foundation Porous microspheres for drug delivery and methods for making same
US5197977A (en) * 1984-01-30 1993-03-30 Meadox Medicals, Inc. Drug delivery collagen-impregnated synthetic vascular graft
US4623588A (en) 1984-02-06 1986-11-18 Biotek, Inc. Controlled release composite core coated microparticles
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
US4578384A (en) * 1984-02-15 1986-03-25 The United States Of America As Represented By The Secretary Of The Army Polylactic-polyglycolic acids combined with an acidic phospholipid-lysozyme complex for healing osseous tissue
CA1295796C (en) 1984-03-27 1992-02-18 Conrad Whyne Biodegradable matrix and methods for producing same
US4837285A (en) 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4765907A (en) 1984-03-28 1988-08-23 Research Development Systems, Inc. Wearable, continuously internally operable and externally regenerable dialysis device
US4596574A (en) 1984-05-14 1986-06-24 The Regents Of The University Of California Biodegradable porous ceramic delivery system for bone morphogenetic protein
US4663049A (en) * 1984-07-05 1987-05-05 University Of Utah Process for therapeutic dissociation of immune complexes and removal of antigens
US4678566A (en) 1984-07-20 1987-07-07 Terumo Kabushiki Kaisha Apparatus for separating proteins from blood plasma
US4661246A (en) * 1984-10-01 1987-04-28 Ash Medical Systems, Inc. Dialysis instrument with dialysate side pump for moving body fluids
JPH0662679B2 (ja) 1985-06-21 1994-08-17 新田ゼラチン株式会社 組織親和性コラ−ゲンとその製法
US4889119A (en) 1985-07-17 1989-12-26 Ethicon, Inc. Surgical fastener made from glycolide-rich polymer blends
US4741337A (en) * 1985-07-17 1988-05-03 Ethicon, Inc. Surgical fastener made from glycolide-rich polymer blends
EP0230654B1 (en) * 1985-12-28 1992-03-18 Sumitomo Pharmaceuticals Company, Limited Sustained pulsewise release pharmaceutical preparation
US5133755A (en) 1986-01-28 1992-07-28 Thm Biomedical, Inc. Method and apparatus for diodegradable, osteogenic, bone graft substitute device
US4968422A (en) 1986-06-23 1990-11-06 Runge Thomas M Pulsatile flow hemodialysis
US5106748A (en) * 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
US5013649A (en) * 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US5187076A (en) * 1986-07-01 1993-02-16 Genetics Institute, Inc. DNA sequences encoding BMP-6 proteins
US4877864A (en) 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
ZA874681B (en) 1986-07-01 1988-04-27 Genetics Inst Novel osteoinductive factors
US4839130A (en) 1986-07-17 1989-06-13 United States Surgical Corporation Process of making an absorbable surgical device
US4744365A (en) * 1986-07-17 1988-05-17 United States Surgical Corporation Two-phase compositions for absorbable surgical devices
JPS6368155A (ja) * 1986-09-11 1988-03-28 グンゼ株式会社 骨接合ピン
US5227157A (en) 1986-10-14 1993-07-13 Board Of Regents, The University Of Texas System Delivery of therapeutic agents
FI80605C (fi) * 1986-11-03 1990-07-10 Biocon Oy Benkirurgisk biokompositmaterial.
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US5051272A (en) 1988-07-19 1991-09-24 United States Surgical Corporation Method for improving the storage stability of a polymeric article susceptible to hydrolytic degradation and resulting article
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
US4844854A (en) 1987-09-22 1989-07-04 United States Surgical Corporation Process for making a surgical device using two-phase compositions
US4822278A (en) * 1987-10-16 1989-04-18 The Wilkinson Dental Manufacturing Company, Inc. Dental veneer instrument
GB8724914D0 (en) * 1987-10-23 1987-11-25 Research Corp Ltd Blood purification apparatus
FR2623402B1 (fr) * 1987-11-19 1994-04-29 Solvay Article en polymere d'acide lactique utilisable notamment comme prothese biodegradable et procede pour sa realisation
US4916193A (en) * 1987-12-17 1990-04-10 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US4961707A (en) 1987-12-22 1990-10-09 University Of Florida Guided periodontal tissue regeneration
US4898734A (en) * 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
US4968590A (en) 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
US5011691A (en) * 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US5108753A (en) * 1988-04-08 1992-04-28 Creative Biomolecules Osteogenic devices
DE3825211A1 (de) 1988-07-25 1990-02-01 Henkel Kgaa Verbesserte koerperresorbierbare knochenwachse (iii)
US5250584A (en) 1988-08-31 1993-10-05 G-C Dental Industrial Corp. Periodontium-regenerative materials
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
DE3837498A1 (de) * 1988-11-04 1990-05-17 Fresenius Ag Verfahren und vorrichtung zur ultrafiltration bei der haemodialyse
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5324520A (en) 1988-12-19 1994-06-28 Vipont Pharmaceutical, Inc. Intragingival delivery systems for treatment of periodontal disease
ATE105177T1 (de) 1988-12-22 1994-05-15 American Cyanamid Co Verfahren zur behandlung von periodontitis durch protrahierte wirkstoffabgabe von arzneimitteln in der zahnhoehle, zusammensetzung davon und vorrichtung zur verabreichung.
US5108755A (en) * 1989-04-27 1992-04-28 Sri International Biodegradable composites for internal medical use
US5534244A (en) 1989-05-24 1996-07-09 Tung; Ming S. Methods and compositions for mineralizing and/or fluoridating calcified tissues with amorphous strontium compounds
US5037639A (en) 1989-05-24 1991-08-06 American Dental Association Health Foundation Methods and compositions for mineralizing calcified tissues
US6056930A (en) * 1989-05-24 2000-05-02 American Dental Association Health Foundation Methods and compositions for mineralizing and fluoridating calcified tissues
US5460803A (en) 1989-05-24 1995-10-24 American Dental Association Health Foundation Methods and compositions for mineralizing and fluoridating calcified tissues
US6000341A (en) 1989-05-24 1999-12-14 American Dental Association Health Foundation Methods and composition for mineralizing and fluoridating calcified tissues
US5077049A (en) 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
US5268178A (en) 1989-09-25 1993-12-07 The Board Of Regents, The University Of Texas System Biodegradable antibiotic implants and methods of their use in treating and preventing infections
US5271961A (en) 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
US5193688A (en) * 1989-12-08 1993-03-16 University Of Utah Method and apparatus for hydrodynamic relaxation and sample concentration NIN field-flow fraction using permeable wall elements
US5185152A (en) * 1990-01-10 1993-02-09 Peyman Gholam A Method and apparatus for controlled release drug delivery to the cornea and anterior chamber of the eye
US5350580A (en) 1990-03-05 1994-09-27 Minnesota Mining And Manufacturing Company Device and method for extended delivery of pharmacologically active agents to the ear
US5288496A (en) 1990-05-15 1994-02-22 Stolle Research & Development Corporation Growth promoters for animals
ES2185615T3 (es) 1990-05-16 2003-05-01 Southern Res Inst Uso y liberacion controlada de las microcapsulas para estimular el crecimiento de la fibra nerviosa.
US5080665A (en) * 1990-07-06 1992-01-14 American Cyanamid Company Deformable, absorbable surgical device
US5324307A (en) 1990-07-06 1994-06-28 American Cyanamid Company Polymeric surgical staple
US5128136A (en) 1990-07-16 1992-07-07 The Oregon Health Sciences University Wound healing kit comprised of gelable collagen
US5081106A (en) * 1990-07-16 1992-01-14 The Oregon Health Sciences University Wound dressing protocol utilizing collagen gelatin formed with iodine
US5231169A (en) 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5114932A (en) * 1990-11-30 1992-05-19 Runge Thomas M Hyperosmolar oxyreplete hemosubstitute
US5206028A (en) 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
US5320624A (en) 1991-02-12 1994-06-14 United States Surgical Corporation Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorbable surgical devices made therefrom
US5171217A (en) 1991-02-28 1992-12-15 Indiana University Foundation Method for delivery of smooth muscle cell inhibitors
US5149691A (en) 1991-03-12 1992-09-22 Creative Biomolecules, Inc. Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
US5284559A (en) * 1992-06-16 1994-02-08 Rhode Island Hospital Preparative electrophoresis device and method
US5281419A (en) * 1992-09-28 1994-01-25 Thomas Jefferson University Biodegradable drug delivery system for the prevention and treatment of osteomyelitis
US5284470A (en) * 1992-11-02 1994-02-08 Beltz Alex D Wearable, portable, light-weight artificial kidney
DE4309410A1 (de) 1993-03-19 1995-02-16 Stange Jan Material, Verfahren und Einrichtung zur selektiven Trennung frei gelöster und stoffgebundener Stoffe aus flüssigen Stoffgemischen sowie Verfahren zur Herstellung des Materials
NL9401260A (nl) 1993-11-12 1995-06-01 Cornelis Johannes Maria Van Ri Membraan voor microfiltratie, ultrafiltratie, gasscheiding en katalyse, werkwijze ter vervaardiging van een dergelijk membraan, mal ter vervaardiging van een dergelijk membraan, alsmede diverse scheidingssystemen omvattende een dergelijk membraan.
US5415532A (en) * 1993-11-30 1995-05-16 The United States Of America As Represented By The Secretary Of The Army High effieciency balanced oscillating shuttle pump
US5577891A (en) 1993-11-30 1996-11-26 Instech Laboratories, Inc. Low power portable resuscitation pump
US5798042A (en) 1994-03-07 1998-08-25 Regents Of The University Of California Microfabricated filter with specially constructed channel walls, and containment well and capsule constructed with such filters
JPH07328110A (ja) 1994-06-10 1995-12-19 Nissho Corp 透析装置の除水制御機構
US5782796A (en) 1995-02-10 1998-07-21 Baxter International Inc. Foldable dialysis unit with integral pump and a method for performing solution exchange
US5591344A (en) 1995-02-13 1997-01-07 Aksys, Ltd. Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof
US5873853A (en) 1995-05-23 1999-02-23 Baxter International Inc. Portable pump apparatus for continuous ambulatory peritoneal dialysis and a method for providing same
US5716852A (en) * 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
DE69628016T2 (de) 1995-06-16 2004-04-01 University Of Washington, Seattle Miniaturisierte differentielle extraktionsvorrichtung und verfahren
US5944684A (en) 1995-08-31 1999-08-31 The Regents Of The University Of California Wearable peritoneum-based system for continuous renal function replacement and other biomedical applications
US20020090644A1 (en) 1999-05-21 2002-07-11 Weigl Bernhard H. Microscale diffusion immunoassay
US5948684A (en) 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
AU3214797A (en) * 1996-05-28 1998-01-05 Regents Of The University Of Michigan, The Engineering oral tissues
AU3570797A (en) 1996-06-14 1998-01-07 University Of Washington Absorption-enhanced differential extraction device
US5833954A (en) 1996-08-20 1998-11-10 American Dental Association Health Foundation Anti-carious chewing gums, candies, gels, toothpastes and dentifrices
ATE211258T1 (de) 1996-09-04 2002-01-15 Scandinavian Micro Biodevices Mikrofliesssystem für die teilchenanalyse und trennung
US5917322A (en) 1996-10-08 1999-06-29 Massachusetts Institute Of Technology Method and apparatus for quantum information processing
US5902336A (en) * 1996-10-15 1999-05-11 Mirimedical, Inc. Implantable device and method for removing fluids from the blood of a patient method for implanting such a device and method for treating a patient experiencing renal failure
US5871360A (en) 1996-12-31 1999-02-16 Gc Corporation Method for restoration of a cavity of a tooth using a resin reinforced type glass ionomer cement
US5855562A (en) 1997-01-07 1999-01-05 Hudson Respiratory Care Inc. Suction control valve
ES2129344B1 (es) 1997-01-07 2000-03-01 Univ Barcelona Autonoma Material remineralizante de tejidos organominerales.
US6001897A (en) * 1997-01-13 1999-12-14 American Dental Association Health Foundation Polymerizable conditioners for adhesive bonding to dentin and enamel
US6128764A (en) 1997-02-06 2000-10-03 California Institute Of Technology Quantum error-correcting codes and devices
US6159739A (en) 1997-03-26 2000-12-12 University Of Washington Device and method for 3-dimensional alignment of particles in microfabricated flow channels
DK0991705T3 (da) 1997-03-31 2004-01-12 Univ Michigan Technology Man W Åbenporede, bionedbrydelige matricer
US5980481A (en) 1997-05-08 1999-11-09 Transvivo, Inc. Method and apparatus for continuous peritoneal cascade dialysis and hemofiltration (CPCD/H)
US6117100A (en) 1997-06-06 2000-09-12 Powers; Kathleen M. Hemodialysis-double dialyzers in parallel
US6472210B1 (en) 1997-11-14 2002-10-29 Bonetec Corporation Polymer scaffold having microporous polymer struts defining interconnected macropores
US6200814B1 (en) 1998-01-20 2001-03-13 Biacore Ab Method and device for laminar flow on a sensing surface
US6114408A (en) * 1998-02-06 2000-09-05 American Dental Association Health Foundation Single-solution adhesive resin formulations
US6582385B2 (en) 1998-02-19 2003-06-24 Nstage Medical, Inc. Hemofiltration system including ultrafiltrate purification and re-infusion system
US6317766B1 (en) 1998-11-02 2001-11-13 Lucent Technologies Inc. Fast quantum mechanical algorithms
SE9803987L (sv) 1998-11-20 2000-05-02 Gambro Ab Förfarande och apparat för att förhindra proteinförlust vid peritonealdialys
US6398859B1 (en) 1998-12-24 2002-06-04 American Dental Association Health Foundation Resin-based pulp capping and basing cements
WO2000050049A2 (en) 1999-02-24 2000-08-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Artificial salivary gland
US6602719B1 (en) 1999-03-26 2003-08-05 Idexx Laboratories, Inc. Method and device for detecting analytes in fluids
US6551842B1 (en) * 1999-03-26 2003-04-22 Idexx Laboratories, Inc. Method and device for detecting analytes in fluids
US6511814B1 (en) 1999-03-26 2003-01-28 Idexx Laboratories, Inc. Method and device for detecting analytes in fluids
US6332985B1 (en) 1999-03-29 2001-12-25 Uop Llc Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions
ATE345827T1 (de) * 1999-04-23 2006-12-15 Renamed Biolog Inc Extrakorporaler kreislauf
US6406631B1 (en) 1999-07-30 2002-06-18 Nephros, Inc. Two stage diafiltration method and apparatus
US7015499B1 (en) * 1999-12-01 2006-03-21 D-Wave Systems, Inc. Permanent readout superconducting qubit
US6459097B1 (en) 2000-01-07 2002-10-01 D-Wave Systems Inc. Qubit using a Josephson junction between s-wave and d-wave superconductors
AU2001249176A1 (en) 2000-03-14 2001-09-24 Micronics, Inc. Microfluidic analysis cartridge
US6527735B1 (en) 2000-04-27 2003-03-04 Renaltech International Llc Method of peritoneal dialysis
US20010048637A1 (en) 2000-05-24 2001-12-06 Weigl Bernhard H. Microfluidic system and method
US20010055546A1 (en) 2000-06-23 2001-12-27 Weigl Bernhard H. Method and apparatus for controlling fluid flow rate in a microfluidic circuit
AU7707801A (en) 2000-07-21 2002-02-05 Us Health Adult human dental pulp stem cells in vitro and in vivo
US20020052571A1 (en) * 2000-09-13 2002-05-02 Fazio Frank A. Artificial kidney and methods of using same
US6899915B2 (en) * 2000-11-29 2005-05-31 President And Fellows Of Harvard College Methods and compositions for culturing a biological tooth
DE20113789U1 (de) 2001-01-10 2002-05-23 B. Braun Melsungen Ag, 34212 Melsungen Medizingerät
US6793725B2 (en) 2001-01-24 2004-09-21 Ada Foundation Premixed calcium phosphate cement pastes
US6758975B2 (en) 2001-02-16 2004-07-06 Piedmont Renal Clinic, Pa Automated peritoneal dialysis system and process with in-line sterilization of dialysate
SE0103013D0 (sv) * 2001-03-09 2001-09-12 Erysave Ab Ideon System and method for treatment of whole blood
US6504172B2 (en) 2001-03-16 2003-01-07 D-Wave Systems, Inc. Superconducting dot/anti-dot flux qubit based on time-reversal symmetry breaking effects
ATE401566T1 (de) 2001-04-03 2008-08-15 Micronics Inc Getrennt fokussierendes zytometer
US6742661B1 (en) * 2001-04-03 2004-06-01 Micronics, Inc. Well-plate microfluidics
US6803599B2 (en) 2001-06-01 2004-10-12 D-Wave Systems, Inc. Quantum processing system for a superconducting phase qubit
US7481936B2 (en) * 2001-10-17 2009-01-27 Transvivo Inc. Method and apparatus for patient fluid management
US7309323B2 (en) * 2001-11-16 2007-12-18 National Quality Care, Inc. Wearable continuous renal replacement therapy device
EP1314442A1 (fr) * 2001-11-26 2003-05-28 Infomed S.A. Dispositif d'épuration intra- et extracorporelle
US6614047B2 (en) 2001-12-17 2003-09-02 D-Wave Systems, Inc. Finger squid qubit device
US6784451B2 (en) 2001-12-18 2004-08-31 D-Wave Systems Inc. Multi-junction phase qubit
US7002174B2 (en) * 2001-12-18 2006-02-21 D-Wave Systems, Inc. Characterization and measurement of superconducting structures
US6796955B2 (en) 2002-02-14 2004-09-28 Chf Solutions, Inc. Method to control blood and filtrate flowing through an extracorporeal device
US6670630B2 (en) 2002-03-16 2003-12-30 D-Wave Systems, Inc. Quantum phase-charge coupled device
US6605822B1 (en) 2002-03-16 2003-08-12 D-Wave Systems, Inc. Quantum phase-charge coupled device
US6911664B2 (en) 2002-04-15 2005-06-28 D-Wave Systems, Inc. Extra-substrate control system
US6900454B2 (en) 2002-04-20 2005-05-31 D-Wave Systems, Inc. Resonant controlled qubit system
US20040009096A1 (en) * 2002-06-08 2004-01-15 Wellman Parris S. Substantially inertia free hemodialysis
AU2003234566A1 (en) 2002-06-11 2003-12-22 Kionix, Inc. Methods and devices for microfluidic extraction
EP1380337B1 (en) * 2002-07-12 2012-11-14 Tosoh Corporation Fine channel device and a chemically operating method for fluid using the device
EP1523351B1 (en) * 2002-07-19 2010-01-06 Baxter International Inc. System for peritoneal dialysis
US7150834B2 (en) 2003-07-31 2006-12-19 Arryx, Inc. Multiple laminar flow-based rate zonal or isopycnic separation with holographic optical trapping of blood cells and other static components
US7118676B2 (en) 2003-09-04 2006-10-10 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US7582482B2 (en) 2002-09-03 2009-09-01 Dionex Corporation Continuous ion species removal device and method
US7094345B2 (en) 2002-09-09 2006-08-22 Cytonome, Inc. Implementation of microfluidic components, including molecular fractionation devices, in a microfluidic system
US6878271B2 (en) * 2002-09-09 2005-04-12 Cytonome, Inc. Implementation of microfluidic components in a microfluidic system
US20050266582A1 (en) 2002-12-16 2005-12-01 Modlin Douglas N Microfluidic system with integrated permeable membrane
US7351218B2 (en) * 2002-12-20 2008-04-01 Gambro Lundia Ab Device and process for extracorporeal treatment by citrate anticoagulant
US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
ATE510605T1 (de) * 2003-03-14 2011-06-15 Univ Columbia Systeme und verfahren für auf blut basierende therapien mit einer membranlosen mikrofluid- austauschvorrichtung
DE10345818A1 (de) 2003-09-30 2005-04-28 Boehringer Ingelheim Micropart Verfahren und Vorrichtung zum Separieren und Abführen von Gasblasen aus Flüssigkeiten
US7309232B2 (en) 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
WO2005062973A2 (en) * 2003-12-24 2005-07-14 Chemica Technologies, Inc. Dialysate regeneration system for portable human dialysis
JP2005224775A (ja) 2004-02-16 2005-08-25 Fuji Xerox Co Ltd 微粒子の処理方法及び処理装置
US7534336B2 (en) 2004-05-04 2009-05-19 Palo Alto Research Center Incorporated Continuous flow particle concentrator
JP2008515551A (ja) * 2004-10-06 2008-05-15 ステイト オブ オレゴン アクティング バイ アンド スルー ザ ステイト ボード オブ ハイヤー エデュケーション オン ビハーフ オブ オレゴン ステイト ユニバーシティー Mecs透析器
US20070196820A1 (en) * 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US20070054293A1 (en) * 2005-08-30 2007-03-08 California Institute Of Technology Microfluidic chaotic mixing systems and methods
US20070179436A1 (en) * 2005-12-21 2007-08-02 Braig James R Analyte detection system with periodic sample draw and laboratory-grade analyzer
US8133194B2 (en) * 2006-02-22 2012-03-13 Henry Ford Health System System and method for delivery of regional citrate anticoagulation to extracorporeal blood circuits
AU2007253702A1 (en) * 2006-05-22 2007-11-29 The Trustees Of Columbia University In The City Of New York Systems and methods of microfluidic membraneless exchange using filtration of extraction fluid outlet streams
US7735652B2 (en) * 2006-06-01 2010-06-15 The Trustees Of Princeton University Apparatus and method for continuous particle separation

Also Published As

Publication number Publication date
BRPI0907473A2 (pt) 2019-09-24
AU2009212396A2 (en) 2010-10-07
EP2249899A1 (en) 2010-11-17
CN102065926A (zh) 2011-05-18
US8496606B2 (en) 2013-07-30
US20110105982A1 (en) 2011-05-05
WO2009100154A1 (en) 2009-08-13
EP2249899A4 (en) 2011-05-11
AU2009212396A1 (en) 2009-08-13
JP2011514182A (ja) 2011-05-06
CA2714594A1 (en) 2009-08-13

Similar Documents

Publication Publication Date Title
MX2010008591A (es) Dispositivos, sistemas y metodos de separacion de fluidos.
WO2010135437A3 (en) Multi-lumen cannula
WO2009146913A3 (de) Organizer zum lösbaren aufnehmen von komponenten von blutschlauchsätzen und verfahren zum herstellen sowie zum vorbereiten desselben
WO2013052951A3 (en) Fluid component separation devices, methods, and systems
WO2011052910A3 (ko) 원심분리 키트 및 이를 이용한 원심분리 방법
WO2009125092A3 (fr) Dispositif d'aliquotage et de filtrage du sang
ATE548061T1 (de) Apheresesysteme mit drei schläuchen
EP2170431A4 (en) DEVICES, METHODS AND SYSTEMS FOR ESTABLISHING AN ADDITIONAL FLOW OF BLOOD OF THE CIRCULATORY SYSTEM
MX2012002495A (es) Dispositivos de tratamiento de dialisis para la remocion de urea.
WO2010122548A3 (en) Assembly, device kit and method for preparing platelet-rich plasma (prp)
WO2009064984A3 (en) Dialysis systems and methods
WO2007103411A3 (en) Wearable kidney
WO2010121750A8 (de) Verfahren zum entfernen von blut aus einem extrakorporalen blutkreislauf, behandlungsvorrichtung sowie schlauchsystem
IN2012DN04847A (es)
MX2019003646A (es) Sistema y metodo para realizar modalidades de dialisis alternativa y secuencial de sangre y peritoneo.
EP2278913A4 (en) AUTOMATED INTERVENTION POINT FLUID ANALYZING DEVICE AND METHOD OF USING THE SAME
WO2008050148A3 (en) Therapy for liver disease
SE0500369L (sv) Bärbart dialyssystem
JP2011514182A5 (ja) ポータブル装置
WO2005123230A3 (en) Dialysis system
WO2007089855A3 (en) Peritoneal dialysis methods and apparatus
WO2010054004A3 (en) Nucleic acid extraction on curved glass surfaces
EP2056899A4 (en) DEVICES, METHODS AND SYSTEMS FOR ESTABLISHING ADDITIONAL BLOOD FLOW IN THE CIRCULATORY SYSTEM
WO2012135573A3 (en) Systems and methods for varying blood flow to identify autoregulatory ranges in a patient
WO2007103390A3 (en) Quick priming connectors for blood circuit

Legal Events

Date Code Title Description
FA Abandonment or withdrawal