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MX2009008143A - Antienos multivariables acomplejados con anticuerpo monoclonal humanizado de apuntamiento. - Google Patents

Antienos multivariables acomplejados con anticuerpo monoclonal humanizado de apuntamiento.

Info

Publication number
MX2009008143A
MX2009008143A MX2009008143A MX2009008143A MX2009008143A MX 2009008143 A MX2009008143 A MX 2009008143A MX 2009008143 A MX2009008143 A MX 2009008143A MX 2009008143 A MX2009008143 A MX 2009008143A MX 2009008143 A MX2009008143 A MX 2009008143A
Authority
MX
Mexico
Prior art keywords
monoclonal antibody
humanized monoclonal
antigens complexed
targeting humanized
multivariable
Prior art date
Application number
MX2009008143A
Other languages
English (en)
Inventor
Gerard Zuraws
Original Assignee
Baylor Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Res Inst filed Critical Baylor Res Inst
Publication of MX2009008143A publication Critical patent/MX2009008143A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/35—Valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Transplantation (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención incluye composiciones y métodos para diseñar, fabricar y usar anticuerpos recombinantes modulares o fragmentos de los mismos con una mitad de un par de cohesina-dockerina que permite el ensamble rápido de conjugados de antígeno multivariantes.
MX2009008143A 2007-02-02 2008-01-31 Antienos multivariables acomplejados con anticuerpo monoclonal humanizado de apuntamiento. MX2009008143A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88802907P 2007-02-02 2007-02-02
PCT/US2008/052714 WO2008097817A2 (en) 2007-02-02 2008-01-31 Multivariable antigens complexed with targeting humanized monoclonal antibody

Publications (1)

Publication Number Publication Date
MX2009008143A true MX2009008143A (es) 2009-10-20

Family

ID=39682338

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008143A MX2009008143A (es) 2007-02-02 2008-01-31 Antienos multivariables acomplejados con anticuerpo monoclonal humanizado de apuntamiento.

Country Status (16)

Country Link
US (3) US7786267B2 (es)
EP (2) EP2684889A3 (es)
JP (1) JP5543785B2 (es)
KR (1) KR20090114425A (es)
CN (1) CN101657464A (es)
AU (1) AU2008214077B2 (es)
BR (1) BRPI0807344A2 (es)
CA (1) CA2715042C (es)
DK (1) DK2114985T3 (es)
ES (1) ES2536900T3 (es)
IL (1) IL200092A0 (es)
MX (1) MX2009008143A (es)
NZ (2) NZ592859A (es)
TW (1) TW200846371A (es)
WO (1) WO2008097817A2 (es)
ZA (1) ZA200905447B (es)

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Also Published As

Publication number Publication date
US20100330115A1 (en) 2010-12-30
EP2114985B1 (en) 2014-12-17
CN101657464A (zh) 2010-02-24
US7786267B2 (en) 2010-08-31
WO2008097817A3 (en) 2008-10-30
CA2715042A1 (en) 2008-08-14
TW200846371A (en) 2008-12-01
JP2010518020A (ja) 2010-05-27
BRPI0807344A2 (pt) 2014-05-20
ES2536900T3 (es) 2015-05-29
NZ592859A (en) 2012-05-25
AU2008214077A1 (en) 2008-08-14
ZA200905447B (en) 2010-05-26
CA2715042C (en) 2021-02-02
IL200092A0 (en) 2010-04-15
US20080254044A1 (en) 2008-10-16
US20160031988A1 (en) 2016-02-04
EP2114985A2 (en) 2009-11-11
EP2114985A4 (en) 2010-09-22
KR20090114425A (ko) 2009-11-03
NZ578657A (en) 2012-02-24
EP2684889A2 (en) 2014-01-15
JP5543785B2 (ja) 2014-07-09
AU2008214077B2 (en) 2012-12-13
DK2114985T3 (en) 2015-03-30
WO2008097817A2 (en) 2008-08-14
EP2684889A3 (en) 2014-03-05

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