MX2009004786A - Derivados de anilinopiperazina y sus metodos de uso. - Google Patents
Derivados de anilinopiperazina y sus metodos de uso.Info
- Publication number
- MX2009004786A MX2009004786A MX2009004786A MX2009004786A MX2009004786A MX 2009004786 A MX2009004786 A MX 2009004786A MX 2009004786 A MX2009004786 A MX 2009004786A MX 2009004786 A MX2009004786 A MX 2009004786A MX 2009004786 A MX2009004786 A MX 2009004786A
- Authority
- MX
- Mexico
- Prior art keywords
- anilinopiperazine derivatives
- methods
- disorder
- disease
- derivatives
- Prior art date
Links
- VDKZSHONJYADKP-UHFFFAOYSA-N n-phenylpiperazin-1-amine Chemical class C1CNCCN1NC1=CC=CC=C1 VDKZSHONJYADKP-UHFFFAOYSA-N 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 5
- 208000035475 disorder Diseases 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 231100000360 alopecia Toxicity 0.000 abstract 1
- 230000001028 anti-proliverative effect Effects 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 208000037906 ischaemic injury Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
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- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract
La presente invención se refiere a nuevos derivados de anilinopiperazina, a composiciones que comprenden los derivados de anilinopiperazina, y a métodos de uso de anilinopiperazina para tratar o prevenir un trastorno proliferativo, un trastorno antiproliferativo, inflamación, artritis, un trastorno del sistema nervioso central, una enfermedad cardiovascular, alopecia, una enfermedad neuronal, una lesión isquémica, una enfermedad viral, una infección fúngica o un trastorno relacionado con la actividad de una proteína quinasa.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85565406P | 2006-10-31 | 2006-10-31 | |
PCT/US2007/022829 WO2008054702A1 (en) | 2006-10-31 | 2007-10-29 | Anilinopiperazine derivatives and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009004786A true MX2009004786A (es) | 2009-06-05 |
Family
ID=39238269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009004786A MX2009004786A (es) | 2006-10-31 | 2007-10-29 | Derivados de anilinopiperazina y sus metodos de uso. |
Country Status (12)
Country | Link |
---|---|
US (1) | US9206142B2 (es) |
EP (1) | EP2078003B1 (es) |
JP (1) | JP5063700B2 (es) |
KR (1) | KR20090075873A (es) |
CN (1) | CN101578275A (es) |
AR (1) | AR063721A1 (es) |
AU (1) | AU2007314342B2 (es) |
CA (1) | CA2668210C (es) |
IL (1) | IL198397A0 (es) |
MX (1) | MX2009004786A (es) |
TW (1) | TW200829583A (es) |
WO (1) | WO2008054702A1 (es) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20090004976A (ko) | 2006-04-19 | 2009-01-12 | 아스테라스 세이야쿠 가부시키가이샤 | 아졸카르복사미드 유도체 |
EP2206707B1 (en) | 2007-10-24 | 2014-07-23 | Astellas Pharma Inc. | Azolecarboxamide compound or salt thereof |
MX2010004878A (es) * | 2007-10-29 | 2010-05-19 | Schering Corp | Derivados de tioeter y eter heterociclico y metodos de uso de los mismos. |
MX2010004875A (es) * | 2007-10-29 | 2010-05-19 | Schering Corp | Derivados de tiazol y metodos para utilizarlos. |
EP2070925A1 (de) * | 2007-12-10 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | Neue 2-substituierte Tiazol-4-carbonsäureamid-Derivative deren Herstellung und Verwendung als Arzneimittel |
EP2070916A1 (de) * | 2007-12-10 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | 2-Aryl-thiazol-4-carbonsäureamid-Derivate, deren Herstellung und Verwendung als Arzneimittel |
EP2070924A1 (de) * | 2007-12-10 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | Neue 2-Hetarylthiazol-4-carbonsäureamid-Derivative, deren Herstellung und Verwendung als Arzneimittel |
US8168794B2 (en) | 2008-03-03 | 2012-05-01 | Novartis Ag | Pim kinase inhibitors and methods of their use |
PE20091577A1 (es) * | 2008-03-03 | 2009-11-05 | Novartis Ag | Inhibidores de cinasa pim y metodos para su uso |
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WO2008054702A1 (en) | 2008-05-08 |
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TW200829583A (en) | 2008-07-16 |
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US9206142B2 (en) | 2015-12-08 |
AU2007314342A1 (en) | 2008-05-08 |
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CA2668210A1 (en) | 2008-05-08 |
CN101578275A (zh) | 2009-11-11 |
US20120328691A1 (en) | 2012-12-27 |
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