MEP22508A - NOVI DERIVATI 1.2,3-SUPSTITUISANOG INDOLIZINA I NHIBUTORI FGFa, POSTUPCI ZA NJIHOVO DOBIJANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVE DERIVATE - Google Patents

NOVI DERIVATI 1.2,3-SUPSTITUISANOG INDOLIZINA I NHIBUTORI FGFa, POSTUPCI ZA NJIHOVO DOBIJANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVE DERIVATE

Info

Publication number: MEP22508A
Authority: ME; Montenegro
Prior art keywords: alk; nr5r6; same; fgfs; inhibitors
Prior art date: 2002-04-04

Application number

MEP-225/08A

Other languages

English (en)

Croatian (hr)

Inventor

Alain Badorc

Francoise Bono

Marie-Francoise Bordes

Nathalie Guillo

Jean-Marc Herbert

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-04

Filing date

2003-04-02

Publication date

2010-06-10

2003-04-02 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2010-06-10 Publication of MEP22508A publication Critical patent/MEP22508A/bs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Pulmonology (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Oncology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MEP-225/08A 2002-04-04 2003-04-02 NOVI DERIVATI 1.2,3-SUPSTITUISANOG INDOLIZINA I NHIBUTORI FGFa, POSTUPCI ZA NJIHOVO DOBIJANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVE DERIVATE MEP22508A (bs)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0204220A FR2838123B1 (fr)	2002-04-04	2002-04-04	Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
PCT/FR2003/001030 WO2003084956A1 (fr)	2002-04-04	2003-04-02	NOUVEAUX DERIVES D'INDOLIZINE 1,2,3 SUBSTITUEE, INHIBITEURS DES FGFs, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

Publications (1)

Publication Number	Publication Date
MEP22508A true MEP22508A (bs)	2010-06-10

Family

ID=28052118

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
MEP-225/08A MEP22508A (bs)	2002-04-04	2003-04-02	NOVI DERIVATI 1.2,3-SUPSTITUISANOG INDOLIZINA I NHIBUTORI FGFa, POSTUPCI ZA NJIHOVO DOBIJANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVE DERIVATE
MEP-2008-225A ME00118B (me)	2002-04-04	2003-04-02	NOVI DERIVATI 1.2,3-SUPSTITUISANOG INDOLIZINA I iNHIBITORI FGFa, POSTUPCI ZA NJIHOVO DOBIJANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVE DERIVATE

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
MEP-2008-225A ME00118B (me)	2002-04-04	2003-04-02	NOVI DERIVATI 1.2,3-SUPSTITUISANOG INDOLIZINA I iNHIBITORI FGFa, POSTUPCI ZA NJIHOVO DOBIJANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVE DERIVATE

Country Status (34)

Country	Link
US (2)	US7442708B2 (bs)
EP (1)	EP1495023B1 (bs)
JP (1)	JP4741799B2 (bs)
KR (1)	KR101022138B1 (bs)
CN (1)	CN100413863C (bs)
AR (1)	AR040404A1 (bs)
AT (1)	ATE304013T1 (bs)
AU (1)	AU2003240984B2 (bs)
BR (1)	BR0309026A (bs)
CA (1)	CA2476056C (bs)
CO (1)	CO5631442A2 (bs)
DE (1)	DE60301570T2 (bs)
DK (1)	DK1495023T3 (bs)
EA (1)	EA007902B1 (bs)
EC (1)	ECSP045338A (bs)
ES (1)	ES2247540T3 (bs)
FR (1)	FR2838123B1 (bs)
HK (1)	HK1074631A1 (bs)
HR (1)	HRP20040912B1 (bs)
IL (2)	IL163755A0 (bs)
IS (1)	IS2475B (bs)
MA (1)	MA27297A1 (bs)
ME (2)	MEP22508A (bs)
MX (1)	MXPA04009639A (bs)
NO (1)	NO329025B1 (bs)
NZ (1)	NZ534786A (bs)
PL (1)	PL215265B1 (bs)
RS (1)	RS51399B (bs)
SI (1)	SI1495023T1 (bs)
TN (1)	TNSN04188A1 (bs)
TW (1)	TWI335222B (bs)
UA (1)	UA78016C2 (bs)
WO (1)	WO2003084956A1 (bs)
ZA (1)	ZA200406613B (bs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2859997B1 (fr) *	2003-09-18	2006-02-03	Sanofi Synthelabo	Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant.
JPWO2005042737A1 (ja) *	2003-11-04	2007-05-10	株式会社ディナベック研究所	遺伝子導入された樹状細胞の製造方法
FR2865934B1 (fr)	2004-02-05	2006-05-05	Sanofi Synthelabo	Utilisation de derives d'indolizine 1,2,3 substitues, inhibiteurs des fgfs, pour la preparation de medicaments utiles pour le traitement de maladies liees a une angiogenese pathologique choroidienne
WO2006001120A1 (ja) *	2004-06-24	2006-01-05	Dnavec Research Inc.	マイナス鎖rnaウイルスを含む抗癌剤
KR20070086595A (ko) *	2004-11-22	2007-08-27	쓰레솔드 파마슈티컬스, 인코포레이티드	튜불린 결합 항암제 및 이의 전구약물
FR2883286B1 (fr) *	2005-03-16	2008-10-03	Sanofi Aventis Sa	NOUVEAUX DERIVES D'IMIDAZO[1,5-a]PYRIDINES, INHIBITEURS DE FGFs, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
FR2896247B1 (fr) *	2006-01-13	2008-02-29	Sanofi Aventis Sa	Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique
EP1891955A1 (en) *	2006-07-24	2008-02-27	Sanofi-Aventis	Use of 1,2,3-substituted indolizine derivatives, inhibitors of FGFs, for the preparation of a medicament intended for the treatment of degenerative joint diseases
CA2735521A1 (en) *	2008-09-04	2010-03-11	Boehringer Ingelheim International Gmbh	Indolizine inhibitors of leukotriene production
WO2010108503A1 (en)	2009-03-24	2010-09-30	Life & Brain Gmbh	Promotion of neuronal integration in neural stem cell grafts
EP2270043A1 (en) *	2009-07-03	2011-01-05	Sanofi-Aventis	Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor
CN101648953B (zh) *	2009-09-24	2012-09-05	绍兴文理学院	一种咪唑并[1，2-b]吡咯并[1，2-f]哒嗪衍生物及其制备方法和用途
FR2962438B1 (fr) *	2010-07-06	2012-08-17	Sanofi Aventis	Derives d'indolizines, procedes de preparation et application en therapeutique
FR2962437B1 (fr)	2010-07-06	2012-08-17	Sanofi Aventis	Derives d'imidazopyridine, leur procede de preparation et leur application en therapeutique
FR2967412B1 (fr) *	2010-11-17	2012-12-14	Sanofi Aventis	Nouveaux derives d'indolizine, leur preparation et leur application en therapeutique
FR2985258A1 (fr) *	2011-12-28	2013-07-05	Sanofi Sa	Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique
AU2015362422B2 (en) *	2014-12-10	2019-11-14	Ono Pharmaceutical Co., Ltd.	Dihydroindolizinone derivative
EP3318563A1 (en) *	2016-11-07	2018-05-09	Sanofi	Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders
CN108864083B (zh) *	2018-06-07	2021-05-25	广东药科大学	一类具有抗癌活性的氨基取代吲嗪类化合物及其衍生物
CN110251513A (zh) *	2019-07-03	2019-09-20	南京大学	一种含吡唑的中氮茚化合物在制备抗肿瘤药物中的应用
US11976066B1 (en)	2023-10-23	2024-05-07	King Faisal University	Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ193926A (en)	1979-07-06	1984-05-31	Labaz Sanofi Nv	2-(alkyl or phenyl)-3(4-hydroxybenzoyl)indolizines
US4378362A (en)	1979-12-06	1983-03-29	S.A. Labaz N.V.	Indolizine derivatives and process for preparing the same
FR2528845A1 (fr) *	1982-06-17	1983-12-23	Sanofi Sa	Nouveaux derives d'indolizine, leur procede de preparation ainsi que les compositions therapeutiques les contenant
FR2594438B1 (fr) *	1986-02-14	1990-01-26	Labaz Sanofi Nv	Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
GB9318790D0 (en) *	1993-09-10	1993-10-27	Fujisawa Pharmaceutical Co	Heterocyclic derivatives
EP1183033B1 (en) *	1999-05-21	2006-03-01	Bristol-Myers Squibb Company	Pyrrolotriazine inhibitors of kinases
WO2002098876A1 (en)	2001-06-06	2002-12-12	Vertex Pharmaceuticals Incorporated	Cak inhibitors and uses thereof
FR2859997B1 (fr) *	2003-09-18	2006-02-03	Sanofi Synthelabo	Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant.

2002
- 2002-04-04 FR FR0204220A patent/FR2838123B1/fr not_active Expired - Fee Related
2003
- 2003-02-04 UA UA20040807138A patent/UA78016C2/uk unknown
- 2003-03-27 TW TW092106944A patent/TWI335222B/zh not_active IP Right Cessation
- 2003-04-02 IL IL16375503A patent/IL163755A0/xx unknown
- 2003-04-02 JP JP2003582153A patent/JP4741799B2/ja not_active Expired - Lifetime
- 2003-04-02 AR AR20030101142A patent/AR040404A1/es active IP Right Grant
- 2003-04-02 ME MEP-225/08A patent/MEP22508A/bs unknown
- 2003-04-02 US US10/509,919 patent/US7442708B2/en not_active Expired - Lifetime
- 2003-04-02 ES ES03730302T patent/ES2247540T3/es not_active Expired - Lifetime
- 2003-04-02 WO PCT/FR2003/001030 patent/WO2003084956A1/fr active IP Right Grant
- 2003-04-02 KR KR1020047015666A patent/KR101022138B1/ko not_active IP Right Cessation
- 2003-04-02 ZA ZA200406613A patent/ZA200406613B/en unknown
- 2003-04-02 MX MXPA04009639A patent/MXPA04009639A/es active IP Right Grant
- 2003-04-02 EP EP03730302A patent/EP1495023B1/fr not_active Expired - Lifetime
- 2003-04-02 CN CNB038077361A patent/CN100413863C/zh not_active Expired - Lifetime
- 2003-04-02 DE DE60301570T patent/DE60301570T2/de not_active Expired - Lifetime
- 2003-04-02 NZ NZ534786A patent/NZ534786A/en not_active IP Right Cessation
- 2003-04-02 DK DK03730302T patent/DK1495023T3/da active
- 2003-04-02 RS YUP-864/04A patent/RS51399B/en unknown
- 2003-04-02 AT AT03730302T patent/ATE304013T1/de active
- 2003-04-02 AU AU2003240984A patent/AU2003240984B2/en not_active Expired
- 2003-04-02 CA CA2476056A patent/CA2476056C/fr not_active Expired - Lifetime
- 2003-04-02 SI SI200330093T patent/SI1495023T1/sl unknown
- 2003-04-02 BR BR0309026-4A patent/BR0309026A/pt not_active IP Right Cessation
- 2003-04-02 PL PL372812A patent/PL215265B1/pl unknown
- 2003-04-02 EA EA200400994A patent/EA007902B1/ru not_active IP Right Cessation
- 2003-04-02 ME MEP-2008-225A patent/ME00118B/me unknown
2004
- 2004-08-19 IS IS7413A patent/IS2475B/is unknown
- 2004-08-26 IL IL163755A patent/IL163755A/en not_active IP Right Cessation
- 2004-09-27 MA MA27876A patent/MA27297A1/fr unknown
- 2004-09-30 TN TNP2004000188A patent/TNSN04188A1/fr unknown
- 2004-09-30 NO NO20044156A patent/NO329025B1/no not_active IP Right Cessation
- 2004-10-01 CO CO04098197A patent/CO5631442A2/es not_active Application Discontinuation
- 2004-10-04 EC EC2004005338A patent/ECSP045338A/es unknown
- 2004-10-04 HR HRP20040912AA patent/HRP20040912B1/hr not_active IP Right Cessation
2005
- 2005-10-04 HK HK05108770A patent/HK1074631A1/xx not_active IP Right Cessation
2008
- 2008-08-26 US US12/198,545 patent/US7803811B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
TNSN04188A1 (fr)	2007-03-12
PL215265B1 (pl)	2013-11-29
PL372812A1 (en)	2005-08-08
JP4741799B2 (ja)	2011-08-10
JP2005532286A (ja)	2005-10-27
FR2838123B1 (fr)	2005-06-10
UA78016C2 (uk)	2007-02-15
RS51399B (en)	2011-02-28
CA2476056A1 (fr)	2003-10-16
CN100413863C (zh)	2008-08-27
HRP20040912A2 (en)	2004-12-31
IS2475B (is)	2008-12-15
CO5631442A2 (es)	2006-04-28
DE60301570T2 (de)	2006-05-18
US20090023770A1 (en)	2009-01-22
IL163755A0 (en)	2005-12-18
AU2003240984A1 (en)	2003-10-20
IL163755A (en)	2010-11-30
RS86404A (en)	2006-12-15
ES2247540T3 (es)	2006-03-01
US7803811B2 (en)	2010-09-28
MXPA04009639A (es)	2005-07-13
WO2003084956A1 (fr)	2003-10-16
FR2838123A1 (fr)	2003-10-10
US7442708B2 (en)	2008-10-28
HK1074631A1 (en)	2005-11-18
NO20044156L (no)	2005-01-03
ME00118B (me)	2010-10-10
EP1495023B1 (fr)	2005-09-07
CA2476056C (fr)	2012-03-06
DK1495023T3 (da)	2005-12-27
EA200400994A1 (ru)	2005-06-30
EP1495023A1 (fr)	2005-01-12
IS7413A (is)	2004-08-19
ZA200406613B (en)	2007-12-27
ATE304013T1 (de)	2005-09-15
TWI335222B (en)	2011-01-01
TW200306181A (en)	2003-11-16
NO329025B1 (no)	2010-08-02
CN1649867A (zh)	2005-08-03
DE60301570D1 (de)	2005-10-13
SI1495023T1 (sl)	2005-12-31
MA27297A1 (fr)	2005-05-02
AU2003240984B2 (en)	2008-07-31
KR101022138B1 (ko)	2011-03-17
EA007902B1 (ru)	2007-02-27
BR0309026A (pt)	2005-02-09
NZ534786A (en)	2006-06-30
HRP20040912B1 (hr)	2012-10-31
ECSP045338A (es)	2005-03-10
AR040404A1 (es)	2005-04-06
KR20040099388A (ko)	2004-11-26
US20050203126A1 (en)	2005-09-15

Publication	Publication Date	Title
MEP22508A (bs)	2010-06-10	NOVI DERIVATI 1.2,3-SUPSTITUISANOG INDOLIZINA I NHIBUTORI FGFa, POSTUPCI ZA NJIHOVO DOBIJANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVE DERIVATE
AR030959A1 (es)	2003-09-03	Derivados de aminoalcoholes, procedimiento para prepararlos, el uso de los mismos para preparar medicamentos y las composiciones farmaceuticas que las contienen
AR037676A1 (es)	2004-12-01	Inhibidores del factor xa y de otras proteasas de serina implicadas en la cascada de la coagulacion; composicion farmaceutica que los comprende y procedimiento para preparar compuestos de formula (i)
GEP20074148B (en)	2007-07-10	Pyrrolo-triazine aniline compounds useful as kinase inhibitors
RS51047B (sr)	2010-10-31	Derivati 4-tetrazolil-4-fenilpiperidina za lečenje bola
HRP20060100T3 (en)	2007-03-31	Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
RU2005116254A (ru)	2006-01-20	Производные пиридопирролизина и пиридоиндолизина
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