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MD4009C2 - Use of 1-methyl-4-(N-methylaminobutyl-4)-b-carboline as antituberculous remedy - Google Patents

Use of 1-methyl-4-(N-methylaminobutyl-4)-b-carboline as antituberculous remedy

Info

Publication number
MD4009C2
MD4009C2 MDA20080198A MD20080198A MD4009C2 MD 4009 C2 MD4009 C2 MD 4009C2 MD A20080198 A MDA20080198 A MD A20080198A MD 20080198 A MD20080198 A MD 20080198A MD 4009 C2 MD4009 C2 MD 4009C2
Authority
MD
Moldova
Prior art keywords
antituberculous
remedy
methylaminobutyl
carboline
methyl
Prior art date
Application number
MDA20080198A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD4009B1 (en
Inventor
Флюр МАКАЕВ
Еуджения СТЫНГАЧ
Даниела ДУКА
Георге ДУКА
Original Assignee
Институт Химии Академии Наук Молдовы
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт Химии Академии Наук Молдовы filed Critical Институт Химии Академии Наук Молдовы
Priority to MDA20080198A priority Critical patent/MD4009C2/en
Publication of MD4009B1 publication Critical patent/MD4009B1/en
Publication of MD4009C2 publication Critical patent/MD4009C2/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention relates to chemistry, namely to the use of brevicarine alkaloid compound as antituberculous remedy.Summary of the invention consists in the use of 1-methyl-4-(N-methylaminobutyl-4)- β-carboline (brevicarine) of general formula:as antituberculous remedy.
MDA20080198A 2008-07-15 2008-07-15 Use of 1-methyl-4-(N-methylaminobutyl-4)-b-carboline as antituberculous remedy MD4009C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20080198A MD4009C2 (en) 2008-07-15 2008-07-15 Use of 1-methyl-4-(N-methylaminobutyl-4)-b-carboline as antituberculous remedy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20080198A MD4009C2 (en) 2008-07-15 2008-07-15 Use of 1-methyl-4-(N-methylaminobutyl-4)-b-carboline as antituberculous remedy

Publications (2)

Publication Number Publication Date
MD4009B1 MD4009B1 (en) 2010-01-29
MD4009C2 true MD4009C2 (en) 2010-08-31

Family

ID=43568882

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20080198A MD4009C2 (en) 2008-07-15 2008-07-15 Use of 1-methyl-4-(N-methylaminobutyl-4)-b-carboline as antituberculous remedy

Country Status (1)

Country Link
MD (1) MD4009C2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4125C1 (en) * 2010-09-17 2012-03-31 Inst De Chimie Al Academiei De Stiinte A Moldovei 1,3,4-Oxadiazole compounds with antituberculous properties containing monosubstituted thiourea

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4404C1 (en) * 2015-03-18 2016-09-30 Институт Химии Академии Наук Молдовы 2-(Propylthio)-5H-[1,3,4]thiadiazole[2,3-b]quinazoline-5-one compound, exhibiting antituberculous activity and method for synthesis thereof

Citations (10)

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SU859889A1 (en) * 1980-01-17 1981-08-30 Читинский Медицинский Институт Method of 1-methyl-4-(n-methylpyrrolidil-1)- -carbolene hydrochloride quantitative determination
RU97105192A (en) * 1996-04-04 1999-04-10 Байер Аг METHODS OF OBTAINING CYCLO-ALKANOINDOL- AND AZAINDOL- AND PYRIMIDO [1,2-A] INDOL-CARBONIC ACIDS AND THEIR ACTIVATED DERIVATIVES IN THE FORM OF PURE ENANTIOMERS AND INTERIM PRODUCTS
RU2001128881A (en) * 1999-03-23 2003-09-27 Холлис-Иден Фармасетикалз, Инк. (Us) IMMUNOMODULATORY STEROIDS, IN PARTICULAR, 16 ALPHA-BROMOEPIANDROSTERONE HEMIDATE 16
UA71629C2 (en) * 1999-08-03 2004-12-15 Lilli Icos Llc Composition containing free drug particulate form of ?-carboline (variants), method for its manufacture (variants), and method for treating sexual dysfunction
RU2004122642A (en) * 2002-01-23 2005-03-10 Фармация Энд Апджон Компани (Us) COMBINED THERAPY FOR TREATMENT OF BACTERIAL INFECTIOUS DISEASES
RU2005137567A (en) * 2003-05-02 2006-04-27 Джорджтаун Юниверсити (Us) Ginkgo Biloba Extract as a Means for the Treatment of Therapeutic Induced Neurotoxicity
UA78839C2 (en) * 2002-07-31 2007-04-25 Lilly Icos Llc Modified pictet-spengler reaction and products prepared therefrom
RU2006110936A (en) * 2003-09-05 2007-10-10 Уайт (Us) APPLICATION OF TIGECYCLINE, SEPARATELY OR IN COMBINATION WITH RIFAMPIN, FOR THE TREATMENT OF OSTEOMYELITIS AND / OR SEPTIC ARTHRITIS
EA010651B1 (en) * 2004-05-28 2008-10-30 Янссен Фармацевтика Н.В. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
RU2007121729A (en) * 2004-11-12 2008-12-20 Панакос Фармасьютикалз NEW BETULIN DERIVATIVES, OBTAINING THE INDICATED COMPOUNDS AND THEIR APPLICATION

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US5817321A (en) * 1992-10-08 1998-10-06 Supratek Pharma, Inc. Biological agent compositions
IT1311923B1 (en) * 1999-04-13 2002-03-20 Nicox Sa PHARMACEUTICAL COMPOUNDS.
IT1311924B1 (en) * 1999-04-13 2002-03-20 Nicox Sa PHARMACEUTICAL COMPOUNDS.
IT1314184B1 (en) * 1999-08-12 2002-12-06 Nicox Sa PHARMACEUTICAL COMPOSITIONS FOR THE THERAPY OF STRESS-OXIDATIVE CONDITIONS
DE19951360A1 (en) * 1999-10-26 2001-05-03 Aventis Pharma Gmbh Substituted indoles
IT1317735B1 (en) * 2000-01-26 2003-07-15 Nicox Sa SALTS OF ANTIMICROBIAL AGENTS.
UA74826C2 (en) * 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors

Patent Citations (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU859889A1 (en) * 1980-01-17 1981-08-30 Читинский Медицинский Институт Method of 1-methyl-4-(n-methylpyrrolidil-1)- -carbolene hydrochloride quantitative determination
RU98100213A (en) * 1995-06-07 1999-11-27 Супратек Фарма, Инк. COMPOSITIONS INCLUDING BIOLOGICAL AGENT
RU97105192A (en) * 1996-04-04 1999-04-10 Байер Аг METHODS OF OBTAINING CYCLO-ALKANOINDOL- AND AZAINDOL- AND PYRIMIDO [1,2-A] INDOL-CARBONIC ACIDS AND THEIR ACTIVATED DERIVATIVES IN THE FORM OF PURE ENANTIOMERS AND INTERIM PRODUCTS
RU2001128881A (en) * 1999-03-23 2003-09-27 Холлис-Иден Фармасетикалз, Инк. (Us) IMMUNOMODULATORY STEROIDS, IN PARTICULAR, 16 ALPHA-BROMOEPIANDROSTERONE HEMIDATE 16
RU2001127576A (en) * 1999-04-13 2003-07-20 Никокс С.А. Pharmaceutical Compositions
RU2001127573A (en) * 1999-04-13 2003-08-10 Никокс С.А. Pharmaceutical Compositions
RU2001127574A (en) * 1999-04-13 2003-09-27 Никокс С.А. Pharmaceutical Compositions
UA71629C2 (en) * 1999-08-03 2004-12-15 Lilli Icos Llc Composition containing free drug particulate form of ?-carboline (variants), method for its manufacture (variants), and method for treating sexual dysfunction
RU2002103509A (en) * 1999-08-12 2003-09-20 Никокс С.А. Pharmaceutical Compounds
RU2002113651A (en) * 1999-10-26 2003-11-20 Авентис Фарма Дойчланд Гмбх SUBSTITUTED INDOLES
RU2002120480A (en) * 2000-01-26 2004-04-27 Никокс С.А. NITRATE SALTS OF ANTI-MICROBIAL AGENTS
RU2002133867A (en) * 2000-05-17 2004-06-27 Орто-Макнейл Фармасьютикал, Инк. BETA-CARBOLINE DERIVATIVES USEFUL AS PHOSPHODIESTHESIS INHIBITORS
RU2004122642A (en) * 2002-01-23 2005-03-10 Фармация Энд Апджон Компани (Us) COMBINED THERAPY FOR TREATMENT OF BACTERIAL INFECTIOUS DISEASES
UA78839C2 (en) * 2002-07-31 2007-04-25 Lilly Icos Llc Modified pictet-spengler reaction and products prepared therefrom
RU2005137567A (en) * 2003-05-02 2006-04-27 Джорджтаун Юниверсити (Us) Ginkgo Biloba Extract as a Means for the Treatment of Therapeutic Induced Neurotoxicity
RU2006110936A (en) * 2003-09-05 2007-10-10 Уайт (Us) APPLICATION OF TIGECYCLINE, SEPARATELY OR IN COMBINATION WITH RIFAMPIN, FOR THE TREATMENT OF OSTEOMYELITIS AND / OR SEPTIC ARTHRITIS
EA010651B1 (en) * 2004-05-28 2008-10-30 Янссен Фармацевтика Н.В. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
RU2007121729A (en) * 2004-11-12 2008-12-20 Панакос Фармасьютикалз NEW BETULIN DERIVATIVES, OBTAINING THE INDICATED COMPOUNDS AND THEIR APPLICATION

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Matcovshi C., Procopişin V., Parii B. Ghid farmacoterapeutic. Chişinău, 2006, p.1093-1095 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4125C1 (en) * 2010-09-17 2012-03-31 Inst De Chimie Al Academiei De Stiinte A Moldovei 1,3,4-Oxadiazole compounds with antituberculous properties containing monosubstituted thiourea

Also Published As

Publication number Publication date
MD4009B1 (en) 2010-01-29

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees