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MC1651A1 - Gluconate de l'amino-2 ethoxycarbonylamino-3(fluoro-4 benzylamino)-6 pyridine et compositions pharmaceutiques renfermant ce compose - Google Patents

Gluconate de l'amino-2 ethoxycarbonylamino-3(fluoro-4 benzylamino)-6 pyridine et compositions pharmaceutiques renfermant ce compose

Info

Publication number
MC1651A1
MC1651A1 MC851765A MC1765A MC1651A1 MC 1651 A1 MC1651 A1 MC 1651A1 MC 851765 A MC851765 A MC 851765A MC 1765 A MC1765 A MC 1765A MC 1651 A1 MC1651 A1 MC 1651A1
Authority
MC
Monaco
Prior art keywords
ethoxycarbonylamino
benzylamino
fluoro
amino
gluconate
Prior art date
Application number
MC851765A
Other languages
English (en)
French (fr)
Inventor
Helmut Hettche
Peter Emig
Jurgen Engel
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of MC1651A1 publication Critical patent/MC1651A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/10—Polyhydroxy carboxylic acids
    • C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC851765A 1984-05-05 1985-05-03 Gluconate de l'amino-2 ethoxycarbonylamino-3(fluoro-4 benzylamino)-6 pyridine et compositions pharmaceutiques renfermant ce compose MC1651A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843416609 DE3416609A1 (de) 1984-05-05 1984-05-05 2-amino-3-ethoxycarbonylamino-6-(p-fluor-benzylamino)- pyridin-gluconat und pharmazeutische zubereitungen, die diese substanz enthalten

Publications (1)

Publication Number Publication Date
MC1651A1 true MC1651A1 (fr) 1986-04-07

Family

ID=6235001

Family Applications (1)

Application Number Title Priority Date Filing Date
MC851765A MC1651A1 (fr) 1984-05-05 1985-05-03 Gluconate de l'amino-2 ethoxycarbonylamino-3(fluoro-4 benzylamino)-6 pyridine et compositions pharmaceutiques renfermant ce compose

Country Status (25)

Country Link
US (1) US4673666A (cs)
EP (1) EP0160865B1 (cs)
JP (1) JPS60239469A (cs)
KR (1) KR850008678A (cs)
AT (1) ATE33638T1 (cs)
AU (1) AU4194385A (cs)
BG (1) BG44537A3 (cs)
CA (1) CA1263398A (cs)
CS (1) CS248743B2 (cs)
DD (1) DD236927A5 (cs)
DE (2) DE3416609A1 (cs)
DK (1) DK157016C (cs)
ES (1) ES8603423A1 (cs)
FI (1) FI80443C (cs)
GR (1) GR851065B (cs)
HU (1) HU193753B (cs)
IE (1) IE57766B1 (cs)
IL (1) IL75086A (cs)
MC (1) MC1651A1 (cs)
NO (1) NO851772L (cs)
PL (1) PL253202A1 (cs)
PT (1) PT80386B (cs)
SU (1) SU1398772A3 (cs)
YU (1) YU71785A (cs)
ZA (1) ZA853351B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689370B1 (en) 1995-04-20 2004-02-10 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US6117432A (en) * 1995-04-20 2000-09-12 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
FR2733151B1 (fr) * 1995-04-20 1997-05-23 Seppic Sa Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
DE10327674A1 (de) 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
EP2346826A2 (en) 2008-06-09 2011-07-27 AWD.pharma GmbH & Co.KG Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine
EP2350009B1 (en) 2008-06-09 2016-03-16 TEVA GmbH Sulfonate salts of flupirtine
DE102010030053A1 (de) 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
WO2012004391A1 (en) 2010-07-09 2012-01-12 K.H.S. Pharma Holding Gmbh Process for the preparation of flupirtine maleate
CN102850265B (zh) * 2011-06-29 2015-11-25 陈小花 一种氟吡汀偶联物及其制备方法和用途
CN102351786A (zh) * 2011-11-01 2012-02-15 东南大学 一种氟吡汀丙二酸盐及其制备方法
CN103910674B (zh) * 2013-12-19 2015-12-02 天津红日药业股份有限公司 用于马来酸氟吡汀分析中的参比化合物
CN104974087A (zh) * 2015-01-30 2015-10-14 吉林修正药业新药开发有限公司 一种氟吡汀二聚体的合成方法
DE102017007385A1 (de) 2017-08-02 2019-02-07 Christoph Hoock Maleatfreie feste Arzneimittelformen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481205A (en) * 1980-09-13 1984-11-06 Degussa Aktiengesellschaft 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate
DE3133519A1 (de) * 1980-09-13 1982-06-09 Degussa Ag, 6000 Frankfurt "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat"

Also Published As

Publication number Publication date
DK157016B (da) 1989-10-30
DK198785D0 (da) 1985-05-02
JPH0144185B2 (cs) 1989-09-26
ES542817A0 (es) 1985-12-16
CA1263398A (en) 1989-11-28
AU4194385A (en) 1985-11-07
FI851752L (fi) 1985-11-06
ATE33638T1 (de) 1988-05-15
YU71785A (en) 1988-02-29
BG44537A3 (en) 1988-12-15
FI851752A0 (fi) 1985-05-03
DE3562242D1 (en) 1988-05-26
IE57766B1 (en) 1993-03-24
IE851117L (en) 1985-11-05
PT80386B (de) 1987-04-16
HU193753B (en) 1987-11-30
DK198785A (da) 1985-11-06
IL75086A0 (en) 1985-09-29
FI80443B (fi) 1990-02-28
DE3416609A1 (de) 1985-11-07
EP0160865A2 (de) 1985-11-13
KR850008678A (ko) 1985-12-21
GR851065B (cs) 1985-11-25
IL75086A (en) 1988-03-31
CS248743B2 (en) 1987-02-12
PT80386A (de) 1985-06-01
ZA853351B (en) 1985-12-24
ES8603423A1 (es) 1985-12-16
NO851772L (no) 1985-11-06
DD236927A5 (de) 1986-06-25
HUT37758A (en) 1986-02-28
PL253202A1 (en) 1986-07-15
JPS60239469A (ja) 1985-11-28
DK157016C (da) 1990-03-26
FI80443C (fi) 1990-06-11
EP0160865A3 (en) 1986-03-12
US4673666A (en) 1987-06-16
SU1398772A3 (ru) 1988-05-23
EP0160865B1 (de) 1988-04-20

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