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LV11547A - Makrolidi ar imunodepresantu aktivitati - Google Patents

Makrolidi ar imunodepresantu aktivitati

Info

Publication number
LV11547A
LV11547A LV960112A LV960112A LV11547A LV 11547 A LV11547 A LV 11547A LV 960112 A LV960112 A LV 960112A LV 960112 A LV960112 A LV 960112A LV 11547 A LV11547 A LV 11547A
Authority
LV
Latvia
Prior art keywords
immunodepressant
macrolides
activity
immunodepressant activity
Prior art date
Application number
LV960112A
Other languages
English (en)
Other versions
LV11547B (en
Inventor
Mark Goulet
Helen M Organ
William H Parsons
Peter J Sinclair
Frederick Wong
Matthew J Wyvratt
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LV11547A publication Critical patent/LV11547A/lv
Publication of LV11547B publication Critical patent/LV11547B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Color Printing (AREA)
LVP-96-112A 1993-10-04 1996-04-15 O-aryl, o-alkyl, o-alkenyl and o-alkynyl- macrolides having immunosuppressive activity LV11547B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/132,072 US5565560A (en) 1991-05-13 1993-10-04 O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
PCT/US1994/011114 WO1995009857A1 (en) 1993-10-04 1994-09-30 O-aryl, o-alkyl, o-alkenyl and o-alkynyl-macrolides having immunosuppressive activity

Publications (2)

Publication Number Publication Date
LV11547A true LV11547A (lv) 1996-10-20
LV11547B LV11547B (en) 1997-02-20

Family

ID=22452330

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-96-112A LV11547B (en) 1993-10-04 1996-04-15 O-aryl, o-alkyl, o-alkenyl and o-alkynyl- macrolides having immunosuppressive activity

Country Status (18)

Country Link
US (2) US5565560A (lv)
EP (1) EP0722448A4 (lv)
JP (1) JPH09503507A (lv)
KR (1) KR960704896A (lv)
CN (1) CN1137275A (lv)
AU (1) AU690157B2 (lv)
BG (1) BG100474A (lv)
BR (1) BR9407720A (lv)
CA (1) CA2172124A1 (lv)
CZ (1) CZ99396A3 (lv)
FI (1) FI961496L (lv)
HU (1) HUT74591A (lv)
LV (1) LV11547B (lv)
NO (1) NO961345L (lv)
NZ (1) NZ275203A (lv)
PL (1) PL313870A1 (lv)
SK (1) SK43096A3 (lv)
WO (1) WO1995009857A1 (lv)

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US7410995B1 (en) 1998-08-14 2008-08-12 Gpi Nil Holdings Inc. N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders
US6218423B1 (en) 1998-08-14 2001-04-17 Gpi Nil Holdings, Inc. Pyrrolidine derivatives for vision and memory disorders
US6506788B1 (en) 1998-08-14 2003-01-14 Gpi Nil Holdings, Inc. N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders
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US7338976B1 (en) 1998-08-14 2008-03-04 Gpi Nil Holdings, Inc. Heterocyclic esters or amides for vision and memory disorders
US6399648B1 (en) 1998-08-14 2002-06-04 Gpi Nil Holdings, Inc. N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders
US6333340B1 (en) 1998-08-14 2001-12-25 Gpi Nil Holdings, Inc. Small molecule sulfonamides for vision and memory disorders
US6384056B1 (en) 1998-08-14 2002-05-07 Gpi Nil Holdings, Inc. Heterocyclic thioesters or ketones for vision and memory disorders
US7265150B1 (en) 1998-08-14 2007-09-04 Gpi Nil Holdings Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
AU2007237187B2 (en) * 2002-07-16 2010-08-05 Biotica Technology Limited Production of polyketides
ES2428354T3 (es) 2002-09-18 2013-11-07 Trustees Of The University Of Pennsylvania Rapamicina para usar en la inhibición o prevención de la neovascularización coroidea
DE10250870A1 (de) * 2002-10-31 2004-05-13 Switch Biotech Ag Zusammensetzung enthaltend Aktivatoren von IK-Kaliumkanälen und Calcineurin-Antagonisten und deren Verwendung
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TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
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CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US9597385B2 (en) 2012-04-23 2017-03-21 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
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EP4100003A4 (en) * 2020-02-07 2024-04-24 Qlaris Bio, Inc. IMPROVED METHODS AND COMPOSITIONS FOR CROMAKALIM PRODRUG THERAPY

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Also Published As

Publication number Publication date
FI961496A0 (fi) 1996-04-03
NO961345D0 (no) 1996-04-02
WO1995009857A1 (en) 1995-04-13
SK43096A3 (en) 1996-10-02
NZ275203A (en) 1998-01-26
KR960704896A (ko) 1996-10-09
BR9407720A (pt) 1997-03-04
AU8073794A (en) 1995-05-01
CZ99396A3 (en) 1996-09-11
CN1137275A (zh) 1996-12-04
AU690157B2 (en) 1998-04-23
EP0722448A4 (en) 1998-04-29
CA2172124A1 (en) 1995-04-13
JPH09503507A (ja) 1997-04-08
BG100474A (en) 1996-12-31
FI961496L (fi) 1996-04-03
EP0722448A1 (en) 1996-07-24
US5565560A (en) 1996-10-15
HUT74591A (en) 1997-01-28
PL313870A1 (en) 1996-07-22
NO961345L (no) 1996-06-03
US5532248A (en) 1996-07-02
HU9600870D0 (en) 1996-06-28
LV11547B (en) 1997-02-20

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