[go: up one dir, main page]

LV10265A - Piridil- un pirimidil-atvasinajumi to iegusanas panemiens farmaceitiska kompozicija un arstesanas metode - Google Patents

Piridil- un pirimidil-atvasinajumi to iegusanas panemiens farmaceitiska kompozicija un arstesanas metode

Info

Publication number
LV10265A
LV10265A LV930577A LV930577A LV10265A LV 10265 A LV10265 A LV 10265A LV 930577 A LV930577 A LV 930577A LV 930577 A LV930577 A LV 930577A LV 10265 A LV10265 A LV 10265A
Authority
LV
Latvia
Prior art keywords
pyridyl
lower alkyl
completed
pharmaceutical composition
treatment method
Prior art date
Application number
LV930577A
Other languages
English (en)
Other versions
LV10265B (en
Inventor
Knut Gunnar Olsson
Aina Lisbeth Abramo
Lundstedt Erik Torbjoern
Nordvi Curt Harry
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of LV10265A publication Critical patent/LV10265A/lv
Publication of LV10265B publication Critical patent/LV10265B/lv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
LVP-93-577A 1988-09-28 1993-06-15 Derivatives of pyridine and pyrimidine, their preparation, pharmaceutical composition and treating method LV10265B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8803429A SE8803429D0 (sv) 1988-09-28 1988-09-28 Novel pyridyl- and pyrimidyl derivatives
HU895103A HU203232B (en) 1988-09-28 1989-09-28 Process for producing new pyridyl and pyrimidinyl derivatives

Publications (2)

Publication Number Publication Date
LV10265A true LV10265A (lv) 1994-10-20
LV10265B LV10265B (en) 1995-08-20

Family

ID=26317811

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-577A LV10265B (en) 1988-09-28 1993-06-15 Derivatives of pyridine and pyrimidine, their preparation, pharmaceutical composition and treating method

Country Status (25)

Country Link
US (1) US5034390A (lv)
EP (1) EP0361271B1 (lv)
JP (1) JP2857693B2 (lv)
KR (1) KR930007413B1 (lv)
CN (1) CN1028756C (lv)
AT (1) ATE97665T1 (lv)
AU (1) AU616307B2 (lv)
CA (1) CA1337417C (lv)
DD (1) DD290884A5 (lv)
DE (1) DE68910922T2 (lv)
DK (1) DK171133B1 (lv)
ES (1) ES2060709T3 (lv)
FI (1) FI94629C (lv)
HU (1) HU203232B (lv)
IE (1) IE62790B1 (lv)
IL (1) IL91701A (lv)
LT (1) LT3549B (lv)
LV (1) LV10265B (lv)
NO (1) NO174667C (lv)
NZ (1) NZ230743A (lv)
PH (1) PH27039A (lv)
PT (1) PT91826B (lv)
RU (1) RU2021269C1 (lv)
SE (1) SE8803429D0 (lv)
ZA (1) ZA897404B (lv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219855A (en) * 1988-01-29 1993-06-15 Mitsubishi Kasei Corporation Anxiolytic drug
IE911774A1 (en) * 1990-06-11 1991-12-18 Akzo Nv Pyridinylpiperazine derivatives
US5166148A (en) * 1990-07-09 1992-11-24 The Du Pont Merck Pharmaceutical Company 2-amino-1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
US5270312A (en) * 1990-11-05 1993-12-14 Warner-Lambert Company Substituted piperazines as central nervous system agents
AU681310B2 (en) * 1994-09-30 1997-08-21 Pfizer Inc. 2,7-substituted octahydro-1h-pyrido{1,2-a}pyrazine derivatives
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
DE19600934A1 (de) 1996-01-12 1997-07-17 Basf Ag Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung
SE9601708D0 (sv) * 1996-05-06 1996-05-06 Pharmacia Ab Pyridyl- and pyrimidyl-piperazines in the treatment of substance abuse disorders
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
CZ299499B6 (cs) 1997-10-27 2008-08-13 Neurosearch A/S Homopiperazinový derivát, farmaceutická kompoziceho obsahující a jeho použití
WO2004083235A2 (en) * 2003-03-19 2004-09-30 Exelixis Inc. Tie-2 modulators and methods of use
WO2018148529A1 (en) * 2017-02-10 2018-08-16 Florida A&M University Identification of agents displaying functional activation of dopamine d2 and d4 receptors

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2979508A (en) * 1959-10-12 1961-04-11 Paul A J Janssen Heterocyclic derivatives of 1-phenyl-omega-(piperazine) alkanols
GB966493A (en) * 1961-11-13 1964-08-12 Soc Ind Fab Antibiotiques Sifa Novel n,n-disubstituted piperazine compounds and their preparation
US4191765A (en) * 1976-05-25 1980-03-04 Hoechst Aktiengesellschaft 1-Aryloxy-2-hydroxy-3-aminopropanes
US4339580A (en) * 1979-06-26 1982-07-13 Mitsubishi Chemical Industries, Limited Piperazinylalkoxyindanes and acid addition salts thereof
CH659069A5 (en) * 1983-11-02 1986-12-31 Sandoz Ag 2-Piperazino- or -homopiperazino-quinazoline derivatives, process for their preparation and pharmaceuticals containing them
US4701456A (en) * 1984-09-19 1987-10-20 Warner-Lambert Company Aminoalkoxybenzopyranones as antipsychotic and anxiolytic agents
US4892943A (en) * 1985-10-16 1990-01-09 American Home Products Corporation Fused bicyclic imides with psychotropic activity
GB8603120D0 (en) * 1986-02-07 1986-03-12 Pfizer Ltd Anti-dysrhythmia agents
US4704390A (en) * 1986-02-13 1987-11-03 Warner-Lambert Company Phenyl and heterocyclic tetrahydropyridyl alkoxy-benzheterocyclic compounds as antipsychotic agents
AR242678A1 (es) * 1986-03-05 1993-04-30 Gonzalez Jorge Alberto Mejoras en instrumentos musicales de cuerda de arco.
MX174210B (es) * 1987-02-17 1994-04-28 Pfizer Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
MX173180B (es) * 1987-10-26 1994-02-07 Pfizer Procedimiento para preparar agentes ansioliticos
JP2712222B2 (ja) * 1988-01-29 1998-02-10 三菱化学株式会社 抗不安薬
US4873331A (en) * 1988-12-09 1989-10-10 American Home Products Corporation Noradamantyl-carboxylic acid piperazinoalkyl esters

Also Published As

Publication number Publication date
KR930007413B1 (ko) 1993-08-10
ES2060709T3 (es) 1994-12-01
PH27039A (en) 1993-02-01
CA1337417C (en) 1995-10-24
RU2021269C1 (ru) 1994-10-15
LV10265B (en) 1995-08-20
DK477189A (da) 1990-03-29
DD290884A5 (de) 1991-06-13
AU616307B2 (en) 1991-10-24
US5034390A (en) 1991-07-23
IE892994L (en) 1990-03-28
PT91826A (pt) 1990-03-30
ATE97665T1 (de) 1993-12-15
NO174667C (no) 1994-06-15
PT91826B (pt) 1995-05-31
AU4173789A (en) 1990-04-05
FI94629B (fi) 1995-06-30
NO893853L (no) 1990-03-29
HU203232B (en) 1991-06-28
DK171133B1 (da) 1996-06-24
NO174667B (no) 1994-03-07
EP0361271A1 (en) 1990-04-04
CN1028756C (zh) 1995-06-07
IL91701A0 (en) 1990-06-10
DE68910922D1 (de) 1994-01-05
HUT51611A (en) 1990-05-28
NZ230743A (en) 1991-08-27
KR900004720A (ko) 1990-04-14
JP2857693B2 (ja) 1999-02-17
SE8803429D0 (sv) 1988-09-28
FI894604L (fi) 1990-03-29
FI94629C (fi) 1995-10-10
JPH02134368A (ja) 1990-05-23
LTIP604A (en) 1995-01-31
EP0361271B1 (en) 1993-11-24
IE62790B1 (en) 1995-03-08
IL91701A (en) 1993-05-13
FI894604A0 (fi) 1989-09-28
CN1041360A (zh) 1990-04-18
DE68910922T2 (de) 1994-03-17
NO893853D0 (no) 1989-09-27
ZA897404B (en) 1990-07-25
DK477189D0 (da) 1989-09-27
LT3549B (en) 1995-11-27

Similar Documents

Publication Publication Date Title
FI900613A0 (fi) Menetelmä farmakologisesti aktiivisten heterosyklisten yhdisteiden valmistamiseksi
LV10265A (lv) Piridil- un pirimidil-atvasinajumi to iegusanas panemiens farmaceitiska kompozicija un arstesanas metode
NL980001I1 (nl) Therapeutische heterocyclische verbindingen.
MX9205542A (es) Compuesto heterociclico nitrogenado.
ATE94534T1 (de) Antiarrhythmische verbindungen.
ATE72431T1 (de) 5-gliedrige heterocyclische angiotensinumwandlungsenzym-inhibitoren.
JO1164B1 (en) A process for preparing useful pyrimidone derivatives as useful 2-antihistamines
GEP19971013B (en) Novel pyridyl and pyrimidyl derivatives process for preparing thereof, and treatment method for mental disorder
MY101878A (en) 1,3,4-thiadiazole
PT79056A (en) Process for preparing pyridyl n-oxides