[go: up one dir, main page]

LU79024A1 - NEW IMIDAZOLES AND THEIR CORRESPONDING SULFOXIDE AND SULPHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NEW IMIDAZOLES AND THEIR CORRESPONDING SULFOXIDE AND SULPHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
LU79024A1
LU79024A1 LU79024A LU79024A LU79024A1 LU 79024 A1 LU79024 A1 LU 79024A1 LU 79024 A LU79024 A LU 79024A LU 79024 A LU79024 A LU 79024A LU 79024 A1 LU79024 A1 LU 79024A1
Authority
LU
Luxembourg
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
corresponding sulfoxide
sulphone derivatives
Prior art date
Application number
LU79024A
Other languages
French (fr)
Inventor
T Sharpe
S Cherkofsky
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/865,832 external-priority patent/US4159338A/en
Application filed by Du Pont filed Critical Du Pont
Publication of LU79024A1 publication Critical patent/LU79024A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LU79024A 1977-02-09 1978-02-08 NEW IMIDAZOLES AND THEIR CORRESPONDING SULFOXIDE AND SULPHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LU79024A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76722077A 1977-02-09 1977-02-09
US05/865,832 US4159338A (en) 1977-02-09 1978-01-05 Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones

Publications (1)

Publication Number Publication Date
LU79024A1 true LU79024A1 (en) 1979-05-25

Family

ID=27117879

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79024A LU79024A1 (en) 1977-02-09 1978-02-08 NEW IMIDAZOLES AND THEIR CORRESPONDING SULFOXIDE AND SULPHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (26)

Country Link
JP (1) JPS53130664A (en)
AR (1) AR219310A1 (en)
AT (1) AT361470B (en)
AU (1) AU517028B2 (en)
CA (1) CA1105024A (en)
CH (1) CH644108A5 (en)
DE (1) DE2805167A1 (en)
DK (1) DK16778A (en)
ES (1) ES466794A1 (en)
FI (1) FI69462C (en)
FR (1) FR2380275A1 (en)
GB (1) GB1564184A (en)
GR (1) GR64142B (en)
HU (1) HU178211B (en)
IE (1) IE46187B1 (en)
IL (1) IL53995A (en)
IT (1) IT1092588B (en)
LU (1) LU79024A1 (en)
MX (1) MX5933E (en)
NL (1) NL7801453A (en)
NO (1) NO148265C (en)
NZ (1) NZ186410A (en)
PH (1) PH13852A (en)
PT (1) PT67626B (en)
SE (1) SE7801467L (en)
YU (1) YU28878A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1302A (en) * 1978-04-11 1985-12-06 Ciba Geigy Ag Mercapto-imidazole derivatives,their preparation,their pharmaceutical compositions and applications
US4199592A (en) * 1978-08-29 1980-04-22 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-nitroimidazoles
DK337779A (en) * 1978-10-02 1980-04-03 Du Pont METHOD FOR PREPARING ANTI-INFLAMMATORY 2-SUBSTITUTED 1H-PHENANTRO (9,10) -IMIDAZOLES
AT374198B (en) * 1979-04-10 1984-03-26 Ciba Geigy Ag METHOD FOR PRODUCING NEW 2-SUBSTITUTED MERCAPTOIMIDAZOLE DERIVATIVES, THEIR N-OXYDES AND THEIR SALTS
FI850995L (en) * 1984-03-16 1985-09-17 Ciba Geigy Ag FOERFARANDE FOER FRAMSTAELLNING AV NYA 3-MERKAPTO-1,2,4-TRIAZACYKLOALKADIENDERIVAT.
EP0994858A1 (en) * 1997-06-30 2000-04-26 Ortho-McNeil Pharmaceutical, Inc. 2-substituted imidazoles useful in the treatment of inflammatory diseases
DE10107683A1 (en) 2001-02-19 2002-08-29 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituted imidazole derivatives and their use in pharmacy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2981739A (en) * 1958-01-27 1961-04-25 Diamond Alkali Co Certain alpha-haloaldehyde addition products of ethylenethioureas and process
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
JPS5343958B2 (en) * 1972-07-29 1978-11-24
SE428686B (en) * 1975-08-11 1983-07-18 Du Pont PROCEDURE FOR PREPARING ANTI-INFLAMMATORALLY ACTIVE IMIDAZOLS

Also Published As

Publication number Publication date
YU28878A (en) 1983-01-21
AU517028B2 (en) 1981-07-02
IT7820078A0 (en) 1978-02-07
NO780433L (en) 1978-08-10
FI780428A (en) 1978-08-10
IE46187B1 (en) 1983-03-23
PT67626B (en) 1979-07-17
AT361470B (en) 1981-03-10
NO148265B (en) 1983-05-30
DE2805167A1 (en) 1978-08-10
NL7801453A (en) 1978-08-11
FI69462B (en) 1985-10-31
FI69462C (en) 1986-02-10
ATA86978A (en) 1980-08-15
IL53995A (en) 1982-02-28
SE7801467L (en) 1978-08-10
JPS53130664A (en) 1978-11-14
FR2380275B1 (en) 1982-01-08
GB1564184A (en) 1980-04-02
GR64142B (en) 1980-01-28
IL53995A0 (en) 1978-04-30
CH644108A5 (en) 1984-07-13
FR2380275A1 (en) 1978-09-08
ES466794A1 (en) 1979-08-01
HU178211B (en) 1982-03-28
NO148265C (en) 1983-09-07
DK16778A (en) 1978-08-10
PT67626A (en) 1978-03-01
NZ186410A (en) 1979-12-11
AR219310A1 (en) 1980-08-15
PH13852A (en) 1980-10-22
IE780279L (en) 1978-08-09
CA1105024A (en) 1981-07-14
MX5933E (en) 1984-08-30
AU3309678A (en) 1979-08-16
IT1092588B (en) 1985-07-12

Similar Documents

Publication Publication Date Title
LU79028A1 (en) NEW IMIDAZOLES AND THEIR CORRESPONDING SULFOXIDE AND SULPHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BE863757A (en) NEW IMIDAZOLES AND THEIR CORRESPONDING SULFOXIDE AND SULPHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2432511B1 (en) TRIAZOLIC DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
BE873656A (en) NEW DERIVATIVES OF PYRIDINE, THEIR PREPARATION AND THEIR USE
FR2343736A1 (en) NEW DERIVATIVES OF SULPHONAMIDE, THEIR PREPARATION PROCESS AND THE THERAPEUTIC COMPOSITIONS CONTAINING THEM
FR2347365A1 (en) TRANS-HEXAHYDRO-PYRIDO-INDOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BE869261A (en) NEW DERIVATIVES OF PEPSTATINE, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM
LU79024A1 (en) NEW IMIDAZOLES AND THEIR CORRESPONDING SULFOXIDE AND SULPHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BE873658A (en) NEW GUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
BE839967R (en) NEW ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
FR2320745A1 (en) NEW ANTI-FLAMMATORY AGENTS IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS
BE848227A (en) NEW HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM,
BE860613A (en) NEW DERIVATIVES OF MORPHANTHRIDINE, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
BE753660A (en) NEW DERIVATIVES OF IMIDAZOLE, THEIR PREPARATION AND THE MEDICINAL COMPOSITIONS CONTAINING THEM
FR2339598A1 (en) NEW DERIVATIVES OF PYRROLIDINE, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
FR2340310A1 (en) SUBSTITUTED HYDRAZINOPHTALAZINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
LU81182A1 (en) NEW ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BE863215A (en) NEW DERIVATIVES OF BENZO (F) ISOQUINOLEINE, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
BE869834A (en) NEW 3-AMINO-17A-AZA-D-HOMO-ANDROSTANE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BE877555A (en) NOVEL DAUNORUBICIN DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2541276B1 (en) DITHIOLANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES
BE839969A (en) NEW ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
BE863802A (en) NEW DERIVATIVES OF EVERNINOMICINE, THEIR METHODS OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAID DERIVATIVES
BE870801A (en) NEW THIOPROPIONAMIDES, THEIR METHODS OF OBTAINING AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING
FR2335225A1 (en) NEW ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS