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KR950704054A - 분배 정치(dispensing apparatus) - Google Patents

분배 정치(dispensing apparatus)

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Publication number
KR950704054A
KR950704054A KR1019950701778A KR19950701778A KR950704054A KR 950704054 A KR950704054 A KR 950704054A KR 1019950701778 A KR1019950701778 A KR 1019950701778A KR 19950701778 A KR19950701778 A KR 19950701778A KR 950704054 A KR950704054 A KR 950704054A
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KR
South Korea
Prior art keywords
liquid
membrane
dispensing
supply means
liquid supply
Prior art date
Application number
KR1019950701778A
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English (en)
Other versions
KR100264246B1 (ko
Inventor
존 로빈 데이비슨
폴 바니스
제프리 브레이스
Original Assignee
엠. 에이. 톨벗
베스팍 피엘씨
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Publication of KR950704054A publication Critical patent/KR950704054A/ko
Application granted granted Critical
Publication of KR100264246B1 publication Critical patent/KR100264246B1/ko

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007Syringe-type or piston-type sprayers or atomisers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0066Inhalators with dosage or measuring devices with means for varying the dose size
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20Mixing gases with liquids
    • B01F23/21Mixing gases with liquids by introducing liquids into gaseous media
    • B01F23/213Mixing gases with liquids by introducing liquids into gaseous media by spraying or atomising of the liquids
    • B01F23/2132Mixing gases with liquids by introducing liquids into gaseous media by spraying or atomising of the liquids using nozzles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/717Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7179Feed mechanisms characterised by the means for feeding the components to the mixer using sprayers, nozzles or jets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0638Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0638Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
    • B05B17/0646Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0653Details
    • B05B17/0676Feeding means

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Biophysics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Nozzles (AREA)
  • Confectionery (AREA)
  • Medicinal Preparation (AREA)
  • Reciprocating Pumps (AREA)

Abstract

분배장치(1)는 그것을 통하여 저장기(16)로부터 액체(19)의 계량된 분량이 분무된 스프레이로서 분산되는 출구(3)를 형성한다. 액체의 액적(19)은 분무된 액적들이 막내에 형성된 구멍(7)들을 통하여 분배되도록 압전 변환기(10)에 의해 진동되는 천공된 막(6)상으로 계량한다. 액체의 계량된 양을 제공하는 전달수단(14)의 각각의 작동시, 변환기는 분배될 액적에 대하여 필요한 분배주기보다 더 큰 주기동안 막을 진동시키도록 작동된다, 상기 장치는 제제들의 분배용으로 특히 적절하다.

Description

분배 정치(DISPENSING APPARATUS)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명에 따른 제1구경의 개략단면도,
제2도는 피펫이 인덱싱 기구를 지니는 변형장치의 개략단면도,
제3도는 계량 펌프를 지니는 부가의 변형장치의 개략단면도,
제4도는 전기 구동된 펌프를 지니는 부가의 변형장치의 개량단면도,
제5도는 가입된 분배 용기가 계량 밸브를 지니는 부가의 변형장치의 개략 단면도.

Claims (16)

  1. 분배출구(3)를 형성하는 하우징(2), 상기 출구에 노출된 전방면(8) 및 사용시 분배될 액체의 의해 접촉되는 후방면(9)을 지니는 천공 막(6), 상기 막을 통해 액체 액적을 분배시키도록 막을 진동시킬 수 있으며 하우징에 연결된 진동수단(10), 하우징에 연결된 액체 공급수단(16) 및 각각 계량된 액체의 량(19)을 액체 공급수단으로부터 전달하여 막의 후방면과 접촉시키도록 연속적으로 작동될 수 있는 전달수단(14)을 포함하며, 사용시 계량된 액체의 량은 막을 통해 분배될 계량된 량에 대해 필요한 분배주기보다 큰 작동 주기동안 진동수단의 작동에 의해 출구에서 분무스프레이로 분배될 수 있는 분배장치(1).
  2. 제1항에 있어서, 액체 공급 수단은 피펫(35)을 포함하며, 전달수단은 피펫으로부터 액체를 이동시키도록 피펫에 이동가능하게 장착된 피스톤(36) 및 각각의 거리를 통해 연속작동으로 피스톤을 이동시켜 계량된 량의 액체를 이동시킬 수 있는 인덱싱수단(37)을 포함하는 분배장치.
  3. 제1항에 있어서, 액체 공급 수단은 액체를 포함하는 저장기(16)를 포함하며, 전달수단은 저장기에 연결된 계량펌프(14)를 포함하며, 상기 계량펌프는 챔버를 형성하는 실린더(42) 및 각가의 작동 행정시 챔버로부터 계량된 체적의 액체를 이동시키도록 실린더에 왕복동가능하게 장착된 피스톤(43)을 포함하는 분배장치.
  4. 제1항에 있어서, 액체 공급 수단은 저장기를 포함하며, 전달수단은 유동액체를 전달할 수 있는 전기구동펌프(51) 및 펌프를 작동시킬 수 있으며 계량된 체적의 액체를 전달한 후 펌프를 접속 및 단절시킬 수 있는 제어수단(52)을 포함하는 분배장치.
  5. 제1항에 있어서, 액체 공급 수단은 공급액체가 압력하에 유지되는 가압된 분배 용기(61)를 포함하며 전달수단은 계량된 체적의 액체를 용기로 부터 방출시킬 수 있는 계량밸브(62)를 포함하는 분배장치.
  6. 제1항에 있어서, 액체 공급 수단은 계량된 체적의 액체를 각각 포함하는 다수의 셀(72)을 포함하며, 전달 수단은 작동시 각각의 셀의 내용물을 배출시키도록 작동가능한 분배스테이션(73)을 포함하는 분배장치.
  7. 선행항중 어느 한 항에 있어서, 하우징은 진동 수단의 주변에 연결되며 막으로 덮여진 중앙구경(5)을 형성하는 환상부재(4)를 포함하는 분배장치.
  8. 제7항에 있어서, 상기 환상부재는 분배장치가 사용시 적합한 작동방향으로 유지될때 방사내향으로 하방으로 경사지도록 오목형으로 되는 상부표면을 포함하는 분배장치.
  9. 제8항에 있어서, 환상부재의 상부표면은 액체 추진재로 형성되는 분배장치.
  10. 제8항 내지 9항 중 어느 한 항에 있어서, 환상부재는 사용시 분배될 액체의 액적(19)을 수용하기 위한 웰(12)을 형성하도록 막과 상호작용하며 구경을 형성하는 최내측의 방사상 표면부(13)를 포함하는 분배장치.
  11. 선행항 중 어느 한 항에 있어서, 하우징은 공기입구(33)와 출구 포트(34)사이를 연통시키는 덕트(32)를 형성하며, 분배 출구는 막의 전방면이 덕트내의 공기에 노출되도록 공기 입구와 출구 포트의 중간의 덕트내에 배치되는 분배장치.
  12. 제11항에 있어서, 공기 임펠러(83)는 덕트를 통해 공기입구로부터 출구 포트까지 공기의 유동을 발생시키도록 작동될 수 있도록 하우징에 연결되는 분배장치.
  13. 제12항에 있어서, 하우징은 덕트와 연통하는 세안용컵(82)을 형성하는 분배장치.
  14. 제11항에 있어서, 출구포트는 구강 또는 비강 사용을 위한 흡입포트(34)를 포함하는 분배장치.
  15. 선행항 중 어느 한 항에 있어서, 진동 수단에 연결되어 진동 수단이 작동되는 동안 작동주기를 결정할 수 있도록 작동가능한 타이머를 포함하며, 작동 주기는 계량된 양이 막을 통해 분배되는데 필요한 분배주기 보다 크게 선택되는 분배장치.
  16. 액체 공급 수단으로부터 계량된 량의 액체를 천공 막의 후방면에 접촉 시키도록 전달하는 단계, 액체의 분무된 스프레이로 막을 통해 분배되도록 막을 진동시키는 단계, 및 계량된 량이 완전히 분배되는데 필요한 분배주기보다 큰 작동주기 동안 막을 연속 진동시키는 단계를 포함하는, 액체를 분무된 스프레이로 분배하는 방법.
    ※ 참고사항:최초출원 내용에 의하여 공개하는 것임.
KR1019950701778A 1992-11-04 1993-10-25 분배 장치 KR100264246B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9223120.8 1992-11-04
GB9223120A GB2272389B (en) 1992-11-04 1992-11-04 Dispensing apparatus
PCT/GB1993/002194 WO1994009912A1 (en) 1992-11-04 1993-10-25 Dispensing apparatus

Publications (2)

Publication Number Publication Date
KR950704054A true KR950704054A (ko) 1995-11-17
KR100264246B1 KR100264246B1 (ko) 2000-08-16

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US (1) US6062212A (ko)
EP (1) EP0682570B1 (ko)
JP (1) JP3241729B2 (ko)
KR (1) KR100264246B1 (ko)
CN (1) CN1038730C (ko)
AU (1) AU670342B2 (ko)
CA (1) CA2144752C (ko)
DE (1) DE69316999T2 (ko)
ES (1) ES2113000T3 (ko)
FI (1) FI951490A0 (ko)
GB (1) GB2272389B (ko)
TW (1) TW235240B (ko)
WO (1) WO1994009912A1 (ko)

Families Citing this family (150)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7628339B2 (en) 1991-04-24 2009-12-08 Novartis Pharma Ag Systems and methods for controlling fluid feed to an aerosol generator
US6540154B1 (en) 1991-04-24 2003-04-01 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US5938117A (en) * 1991-04-24 1999-08-17 Aerogen, Inc. Methods and apparatus for dispensing liquids as an atomized spray
US5518179A (en) * 1991-12-04 1996-05-21 The Technology Partnership Limited Fluid droplets production apparatus and method
US5724957A (en) * 1993-01-29 1998-03-10 Aradigm Corporation Intrapulmonary delivery of narcotics
US5819730A (en) * 1993-06-09 1998-10-13 Glaxo Wellcome Australia Ltd. Device for administering pharmaceutical substances
BR9406968A (pt) * 1993-06-29 1996-08-06 Voges Innovation Pty Ltd Dispensador
GB9324250D0 (en) * 1993-11-25 1994-01-12 Minnesota Mining & Mfg Inhaler
US6000394A (en) * 1994-10-26 1999-12-14 Paul Rizau Pari-Werk Gmbh Generation of an aerosol of an exact dose
CA2215331C (en) * 1995-03-14 2002-01-22 Siemens Aktiengesellschaft Ultrasonic atomizer device with removable precision dosating unit
US5970974A (en) * 1995-03-14 1999-10-26 Siemens Aktiengesellschaft Dosating unit for an ultrasonic atomizer device
US6205999B1 (en) * 1995-04-05 2001-03-27 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US5758637A (en) * 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6085740A (en) 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
US6782886B2 (en) 1995-04-05 2004-08-31 Aerogen, Inc. Metering pumps for an aerosolizer
US6014970A (en) 1998-06-11 2000-01-18 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US6427682B1 (en) * 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
EP0778001B1 (en) 1995-05-12 2004-04-07 Seiko Epson Corporation Apparatus for diagnosing condition of living organism and control unit
AU5549498A (en) * 1997-01-17 1998-08-07 Per Andersen Aerosol inhaler device
US6672129B1 (en) 1997-10-22 2004-01-06 Microfab Technologies, Inc. Method for calibrating a sensor for measuring concentration of odors
US6390453B1 (en) 1997-10-22 2002-05-21 Microfab Technologies, Inc. Method and apparatus for delivery of fragrances and vapors to the nose
US6397838B1 (en) * 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
US6196218B1 (en) * 1999-02-24 2001-03-06 Ponwell Enterprises Ltd Piezo inhaler
US6702196B2 (en) * 1999-03-31 2004-03-09 Ngk Insulators, Ltd. Circuit for driving liquid drop spraying apparatus
US6338715B1 (en) 1999-03-31 2002-01-15 Microfab Technologies, Inc. Digital olfactometer and method for testing olfactory thresholds
SE9902627D0 (sv) * 1999-07-08 1999-07-08 Siemens Elema Ab Medical nebulizer
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US6530370B1 (en) * 1999-09-16 2003-03-11 Instrumentation Corp. Nebulizer apparatus
DE19953317C1 (de) * 1999-11-05 2001-02-01 Pari Gmbh Inhalationsvernebler
US6962151B1 (en) * 1999-11-05 2005-11-08 Pari GmbH Spezialisten für effektive Inhalation Inhalation nebulizer
US6748944B1 (en) * 2000-05-03 2004-06-15 Dellavecchia Michael Anthony Ultrasonic dosage device and method
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US7100600B2 (en) 2001-03-20 2006-09-05 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US6948491B2 (en) 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
MXPA02010884A (es) 2000-05-05 2003-03-27 Aerogen Ireland Ltd Aparato y metodo para el suministro de medicamentos al sistema respiratorio.
US7600511B2 (en) 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US6629524B1 (en) 2000-07-12 2003-10-07 Ponwell Enterprises Limited Inhaler
US6543443B1 (en) 2000-07-12 2003-04-08 Aerogen, Inc. Methods and devices for nebulizing fluids
CN1781559A (zh) * 2000-10-05 2006-06-07 欧姆龙健康医疗事业株式会社 液体雾化装置
EP1344545A1 (en) * 2000-10-05 2003-09-17 Omron Corporation Liquid atomizer
JP2007307560A (ja) * 2000-10-05 2007-11-29 Omron Healthcare Co Ltd 液体霧化装置
US6769626B1 (en) 2000-10-30 2004-08-03 Instrumentarium Corp. Device and method for detecting and controlling liquid supply to an apparatus discharging liquids
EP1205200A1 (en) * 2000-11-13 2002-05-15 The Technology Partnership Public Limited Company Triggering circuit for an aerosol drug-dispensing device
FR2817844B1 (fr) 2000-12-08 2003-03-28 Valois Sa Distributeur de produit fluide
DE10102846B4 (de) * 2001-01-23 2012-04-12 Pari Pharma Gmbh Aerosolgenerator
US20030072717A1 (en) * 2001-02-23 2003-04-17 Vapotronics, Inc. Inhalation device having an optimized air flow path
WO2002072169A2 (en) * 2001-03-09 2002-09-19 Antares Pharma, Inc. Ocular drug delivery nebulizer
US6546927B2 (en) 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
DE60205093T2 (de) 2001-03-15 2006-05-24 The Government of the United States of America, as represented by the Secretary, Centers for Disease Control and Prevention Vernebler mit kühlkammer
AU2002258961A1 (en) 2001-04-24 2002-11-05 Medi-Physics, Inc. Methods and devices for moisturizing hyperpolarized noble gases and pharmaceutical products thereof
US6554201B2 (en) * 2001-05-02 2003-04-29 Aerogen, Inc. Insert molded aerosol generator and methods
US6732944B2 (en) 2001-05-02 2004-05-11 Aerogen, Inc. Base isolated nebulizing device and methods
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
CA2472644C (en) 2002-01-07 2013-11-05 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US6851626B2 (en) * 2002-01-07 2005-02-08 Aerogen, Inc. Methods and devices for nebulizing fluids
ES2603067T3 (es) 2002-01-15 2017-02-23 Novartis Ag Métodos y sistemas para hacer funcionar un generador de aerosol
GB2384198B (en) * 2002-01-18 2005-03-02 Profile Drug Delivery Ltd Nebulizer metering
WO2003068412A1 (en) * 2002-02-11 2003-08-21 Sara Lee/De N.V. Liquid spray-head, apparatus comprising a liquid spray-head and container therefore
US6915962B2 (en) * 2002-05-20 2005-07-12 Aerogen, Inc. Apparatus for providing aerosol for medical treatment and methods
US20040039755A1 (en) * 2002-06-05 2004-02-26 Matthew Kunze Metadata relationships
US6827559B2 (en) * 2002-07-01 2004-12-07 Ventaira Pharmaceuticals, Inc. Piezoelectric micropump with diaphragm and valves
DK1539366T3 (da) * 2002-08-06 2009-07-06 Glaxo Group Ltd Afgiveindretning
DE10257381B4 (de) 2002-12-09 2006-09-14 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung
US6969008B2 (en) * 2003-01-29 2005-11-29 S. C. Johnson & Son, Inc. Point of purchase fragrance sampling
US7125727B2 (en) * 2003-01-29 2006-10-24 Protedyne Corporation Sample handling tool with piezoelectric actuator
DE10306683A1 (de) * 2003-02-13 2004-09-09 Ing. Erich Pfeiffer Gmbh Mikrodosiereinrichtung
JP2004283802A (ja) * 2003-03-25 2004-10-14 Omron Healthcare Co Ltd 液体霧化装置
GB2400839B (en) * 2003-04-22 2005-10-19 Bespak Plc Dispensing apparatus
US8012136B2 (en) 2003-05-20 2011-09-06 Optimyst Systems, Inc. Ophthalmic fluid delivery device and method of operation
CA2526362C (en) 2003-05-20 2012-10-09 James F. Collins Ophthalmic drug delivery system
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
JP4411901B2 (ja) * 2003-08-11 2010-02-10 セイコーエプソン株式会社 霧化装置
EP1559436B1 (en) 2004-01-26 2011-05-25 EP Systems SA Spray system for atomising liquids
US7380550B2 (en) 2004-01-30 2008-06-03 Hewlett-Packard Development Company, L.P. Systems and methods for particle detection
US7819115B2 (en) * 2004-01-30 2010-10-26 Hewlett-Packard Development Company, L.P. Inhalers and methods of controlling airflow in inhalers
GB0402695D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A metering pump system
GB0402690D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402697D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
AU2005262940B2 (en) 2004-04-02 2010-07-01 Creare Incorporated Aerosol delivery systems and methods
US7290541B2 (en) 2004-04-20 2007-11-06 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
US7267121B2 (en) 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
EP1604701B1 (en) * 2004-06-09 2010-12-15 Microflow Engineering SA Improved modular liquid spray system
TWI547431B (zh) * 2004-06-09 2016-09-01 史密斯克萊美占公司 生產藥物之裝置及方法
US7775459B2 (en) * 2004-06-17 2010-08-17 S.C. Johnson & Son, Inc. Liquid atomizing device with reduced settling of atomized liquid droplets
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
DE102005006375B4 (de) * 2005-02-11 2007-10-11 Pari GmbH Spezialisten für effektive Inhalation Aerosolerzeugungsvorrichtung für Inhalationstherapiegeräte
AU2006249574B2 (en) 2005-05-25 2012-01-19 Novartis Ag Vibration systems and methods
US7490815B2 (en) * 2005-11-14 2009-02-17 The Procter & Gamble Company Delivery system for dispensing volatile materials using an electromechanical transducer in combination with an air disturbance generator
EP1792662A1 (en) 2005-11-30 2007-06-06 Microflow Engineering SA Volatile liquid droplet dispenser device
JP5041550B2 (ja) * 2006-08-01 2012-10-03 日本たばこ産業株式会社 エアロゾル吸引器
WO2009111612A1 (en) * 2008-03-07 2009-09-11 Novartis Ag Aerosolization device
JP5339842B2 (ja) * 2008-10-06 2013-11-13 キヤノン株式会社 吐出ヘッド及び液滴吐出装置
US9132244B2 (en) 2009-11-04 2015-09-15 Koninklijke Philips N.V. Medication delivery apparatus including a medication metering system
US9180261B2 (en) 2010-01-12 2015-11-10 Dance Biopharm Inc. Preservative free insulin formulations and systems and methods for aerosolizing
US20130269684A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Methods and systems for supplying aerosolization devices with liquid medicaments
US10857311B2 (en) 2010-01-12 2020-12-08 Omega Life Science Ltd. Method and apparatus for producing fine concentrated aerosol
US20110303762A1 (en) * 2010-06-10 2011-12-15 Gojo Industries, Inc. Piezoelectric foaming pump
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
US8733935B2 (en) 2010-07-15 2014-05-27 Corinthian Ophthalmic, Inc. Method and system for performing remote treatment and monitoring
JP5964826B2 (ja) 2010-07-15 2016-08-03 アイノビア,インコーポレイティド 滴生成デバイス
US9087145B2 (en) 2010-07-15 2015-07-21 Eyenovia, Inc. Ophthalmic drug delivery
US9068566B2 (en) 2011-01-21 2015-06-30 Biodot, Inc. Piezoelectric dispenser with a longitudinal transducer and replaceable capillary tube
JP6306502B2 (ja) * 2011-05-10 2018-04-04 フラウンホッファー−ゲゼルシャフト ツァ フェルダールング デァ アンゲヴァンテン フォアシュンク エー.ファオ 制御可能な流体サンプル・ディスペンサおよびそれを用いた方法
EP2706838B1 (en) * 2011-05-10 2016-11-09 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V. Controllable scent sample dispenser
JP5405533B2 (ja) * 2011-07-20 2014-02-05 パナソニック株式会社 ミスト発生装置及び美容装置
JP6105621B2 (ja) 2011-12-12 2017-03-29 アイノビア,インコーポレイティド 高弾性高分子エジェクタ機構、エジェクタ装置及びそれらの使用方法
AT513810B1 (de) * 2012-12-18 2015-02-15 Harald Ing Rauchenschwandtner Ein Verfahren und eine Vorrichtung zum Ausbringen von wässrigen polymerhaltigen Bioziden mittels Ultraschalltechnologie im Raum
CN105451891B (zh) * 2013-08-08 2018-09-14 东芝三菱电机产业系统株式会社 雾化装置
JP6401273B2 (ja) * 2013-08-16 2018-10-10 ベクチュラ・ゲーエムベーハー 吸入装置用投与システム
ITRM20130562A1 (it) * 2013-10-11 2015-04-12 Manuele Casale Dispositivo di erogazione di una sostanza in forma di aerosol
CN103657750A (zh) * 2013-11-19 2014-03-26 梁福鹏 一种具备分注功能的试剂瓶
GB2522727B (en) * 2013-11-26 2017-01-25 Purity Health Pharma Ltd Pulmonary delivery devices
US10265216B2 (en) * 2014-01-31 2019-04-23 Eye-go A/S Device for applying an ophthalmic fluid
JP6363388B2 (ja) * 2014-05-01 2018-07-25 ロレアル ミストスプレー装置
US10307550B2 (en) 2014-06-09 2019-06-04 Dance Biopharm Inc. Liquid drug cartridges and associated dispenser
US10052443B2 (en) 2014-10-13 2018-08-21 Omega Life Science Ltd. Nebulizers and uses thereof
CA2973471A1 (en) 2015-01-12 2016-07-21 Kedalion Therapeutics, Inc. Micro-droplet delivery device and methods
CN107530509A (zh) * 2015-04-10 2018-01-02 科达莱昂治疗公司 具有可替换安瓿的压电分配器
WO2017115197A1 (en) * 2015-12-28 2017-07-06 Koninklijke Philips N.V. Aerosol generator device and nebulizer system with such a device
WO2017192773A1 (en) 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency
CN109475709B (zh) 2016-05-03 2022-12-27 精呼吸股份有限公司 使用液滴输送装置生成液滴并将其输送到肺部系统的方法
US11285285B2 (en) 2016-05-03 2022-03-29 Pneuma Respiratory, Inc. Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment
WO2017192774A1 (en) 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device
WO2017220273A1 (en) * 2016-06-20 2017-12-28 Philip Morris Products S.A. Vaporiser assembly for an aerosol-generating system
US10881140B2 (en) 2016-06-20 2021-01-05 Altria Client Services Llc Vaporiser assembly for an aerosol-generating system
CA3039106A1 (en) 2017-01-20 2018-07-26 Kedalion Therapeutics, Inc. Piezoelectric fluid dispenser
ES2979350T3 (es) * 2017-03-23 2024-09-25 Stamford Devices Ltd Dispositivo de suministro de aerosol
WO2018213834A1 (en) 2017-05-19 2018-11-22 Pneuma Respiratory, Inc. Dry powder delivery device and methods of use
AU2018279940B2 (en) * 2017-06-10 2023-12-14 Eyenovia, Inc. Methods and devices for handling a fluid and delivering the fluid to the eye
US11738158B2 (en) 2017-10-04 2023-08-29 Pneuma Respiratory, Inc. Electronic breath actuated in-line droplet delivery device and methods of use
CA3079189A1 (en) 2017-10-17 2019-04-25 Pneuma Respiratory, Inc. Nasal drug delivery apparatus and methods of use
DE102017124742A1 (de) * 2017-10-23 2019-04-25 Nebu-Tec Med. Produkte Eike Kern Gmbh Automatische Medikamentendosierung bei Verneblern
JP2021502178A (ja) 2017-11-08 2021-01-28 ニューマ・リスパイラトリー・インコーポレイテッド 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法
JP7436363B2 (ja) 2017-12-08 2024-02-21 ノバルティス アーゲー 流体送達アライメントシステム
US12186234B2 (en) 2018-04-12 2025-01-07 Bausch + Lomb Ireland Limited Topical ocular delivery methods and devices for use in the same
US20220001122A1 (en) * 2018-10-01 2022-01-06 Pneuma Respiratory, Inc. Delivery of low surface tension compositions to the pulmonary system via electronic breath actuated droplet delivery device
DE202019000718U1 (de) * 2019-02-14 2019-02-26 WERRTA GmbH Düsen- und Zerstäubungstechnik Inhalator
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
US12097145B2 (en) 2019-03-06 2024-09-24 Bausch + Lomb Ireland Limited Vented multi-dose ocular fluid delivery system
CN115038414A (zh) 2019-12-11 2022-09-09 艾诺维亚股份有限公司 用于向眼睛输送流体的系统和装置及使用方法
AU2021257273A1 (en) 2020-04-17 2022-11-17 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
EP4120973A4 (en) 2020-04-17 2024-04-17 Bausch + Lomb Ireland Limited HYDRODYNAMIC ACTUATED PRESERVATIVE-FREE DISPENSING SYSTEM WITH COLLAPSIBLE LIQUID CONTAINER
JP2024525200A (ja) 2021-06-22 2024-07-10 ニューマ・リスパイラトリー・インコーポレイテッド プッシュ排出を用いる液滴送達デバイス
DE102021003634A1 (de) 2021-07-14 2023-01-19 Lea Boberschmidt Zerstäubungsvorrichtung zur Zerstäubung von Flüssigkeiten
US12161795B2 (en) 2022-07-18 2024-12-10 Pneuma Respiratory, Inc. Small step size and high resolution aerosol generation system and method
JP7179399B1 (ja) * 2022-08-01 2022-11-29 合同会社クオビス 点眼補助具
CN118208790A (zh) * 2024-04-29 2024-06-18 桐乡清锋科技有限公司 一种可实现稳定雾化的加湿装置

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3790079A (en) * 1972-06-05 1974-02-05 Rnb Ass Inc Method and apparatus for generating monodisperse aerosol
US3806100A (en) * 1972-09-06 1974-04-23 Respiratory Care Reservoir for ultrasonically operated nebulizer
DE2445791C2 (de) * 1974-09-25 1984-04-19 Siemens AG, 1000 Berlin und 8000 München Ultraschall-Flüssigkeitszerstäuber
US4465234A (en) * 1980-10-06 1984-08-14 Matsushita Electric Industrial Co., Ltd. Liquid atomizer including vibrator
US4605167A (en) * 1982-01-18 1986-08-12 Matsushita Electric Industrial Company, Limited Ultrasonic liquid ejecting apparatus
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
FI69962C (fi) * 1983-12-28 1986-09-12 Huhtamaeki Oy Inhalationsanordning
EP0156409A3 (en) * 1984-02-23 1986-06-25 Jean Michel Anthony Device for moistening parts of the human body
DE3524701A1 (de) * 1985-07-11 1987-01-15 Bosch Gmbh Robert Ultraschallzerstaeuberduese
DE3627222A1 (de) * 1986-08-11 1988-02-18 Siemens Ag Ultraschall-taschenzerstaeubergeraet
DE3810262A1 (de) * 1988-03-25 1989-10-12 Henning Berlin Gmbh Vorrichtung zur dosierten verabreichung eines fluessigen arzneimittels
GB8924823D0 (en) * 1989-11-03 1989-12-20 Smith Kline French Lab Dosage inhalers
US5152456A (en) * 1989-12-12 1992-10-06 Bespak, Plc Dispensing apparatus having a perforate outlet member and a vibrating device
DE69117127T2 (de) * 1990-10-11 1996-11-07 Toda Koji Ultraschall-Zerstäuber
GB2265845B (en) * 1991-11-12 1996-05-01 Medix Ltd A nebuliser and nebuliser control system
US5518179A (en) * 1991-12-04 1996-05-21 The Technology Partnership Limited Fluid droplets production apparatus and method
US5586550A (en) * 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system

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CA2144752C (en) 2001-02-06
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US6062212A (en) 2000-05-16
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AU5341894A (en) 1994-05-24

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