KR930008138A - 특정한 뉴클레오티드 시퀀스를 포함하는 약독화(弱毒化)된 홍역 백신 바이러스 균주와 그의 완벽한 동정 방법 - Google Patents
특정한 뉴클레오티드 시퀀스를 포함하는 약독화(弱毒化)된 홍역 백신 바이러스 균주와 그의 완벽한 동정 방법 Download PDFInfo
- Publication number
- KR930008138A KR930008138A KR1019920003759A KR920003759A KR930008138A KR 930008138 A KR930008138 A KR 930008138A KR 1019920003759 A KR1019920003759 A KR 1019920003759A KR 920003759 A KR920003759 A KR 920003759A KR 930008138 A KR930008138 A KR 930008138A
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- South Korea
- Prior art keywords
- measles vaccine
- vaccine virus
- specific nucleotide
- nucleotide sequences
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- Prior art date
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- 229940041323 measles vaccine Drugs 0.000 title claims abstract 8
- 241000700605 Viruses Species 0.000 title claims abstract 7
- 108091028043 Nucleic acid sequence Proteins 0.000 title claims description 4
- 238000000034 method Methods 0.000 title claims 6
- 230000002238 attenuated effect Effects 0.000 title 1
- 239000002773 nucleotide Substances 0.000 claims abstract 6
- 125000003729 nucleotide group Chemical group 0.000 claims abstract 6
- 230000003612 virological effect Effects 0.000 claims abstract 4
- 238000000636 Northern blotting Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 238000003752 polymerase chain reaction Methods 0.000 claims 1
- 229940124862 Measles virus vaccine Drugs 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18421—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (54)
- 홍역 바이러스 백신과 종자 바이러스에서 하기 시퀀스의 15894개의 뉴클레오티드로 이루어진 전체 바이러스 게놈 RNA으로 이루어진 특정 뉴클레오티드 시퀀스를 포함하는 홍역백신 바이러스 균주
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- 제1항에 있어서, 돌연변이 시퀀스 또는 손상된 시퀀스의 부분적인 첨가를 가지는 뉴클레오티드 시퀀스로 이루어진 바이러스 게놈 RNA로 구성되는 홍역 백신 바이러스.
- 홍역 백신 바이러스 균주의 게놈 RNA 중에서 제1항에 의한 15894개의 뉴클레오티드로 이루어진 특정 뉴클레오티드 시퀀스를 탐지하는 것으로 이루어진 홍역 백신 바이러스 균주에 대한 완벽한 동정 방법.
- 제3항에 있어서, 완벽한 동정 방법은 노던 블릇 테크닉과 폴리머레이즈 체인 반응 방법으로 바이러스 게놈 RNA의 뉴클레오티드 시퀀스의 부분을 검출하는 것이 특징인 동정 방법.
- ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP91-293625 | 1991-10-14 | ||
JP3293625A JP3045581B2 (ja) | 1991-10-14 | 1991-10-14 | 麻疹ワクチンウイルス株同定方法 |
JP293625 | 1991-10-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR930008138A true KR930008138A (ko) | 1993-05-21 |
KR950012759B1 KR950012759B1 (ko) | 1995-10-21 |
Family
ID=17797135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019920003759A Expired - Lifetime KR950012759B1 (ko) | 1991-10-14 | 1992-03-07 | 특정 염기 배열을 포함하는 약독화(弱毒化)된 홍역 백신 바이러스주 및 그의 절대적 동정법 |
Country Status (10)
Country | Link |
---|---|
US (2) | US5654136A (ko) |
EP (1) | EP0540135B1 (ko) |
JP (1) | JP3045581B2 (ko) |
KR (1) | KR950012759B1 (ko) |
AT (1) | ATE193726T1 (ko) |
DE (1) | DE69231143T2 (ko) |
DK (1) | DK0540135T3 (ko) |
ES (1) | ES2148164T3 (ko) |
GR (1) | GR3034278T3 (ko) |
PT (1) | PT540135E (ko) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2133339A1 (en) * | 1992-04-08 | 1993-10-09 | Jennifer S. Rota | Wild-type measles virus glycoproteins: vaccine and detection method therefor |
US6638482B1 (en) * | 1993-11-01 | 2003-10-28 | Nanogen, Inc. | Reconfigurable detection and analysis apparatus and method |
AU4452897A (en) * | 1996-07-31 | 1998-02-25 | Claude P. Muller | Peptides |
BR9712138A (pt) * | 1996-09-27 | 2000-01-18 | American Cyanamid Co | Vìrus de rna isolado, vacina, processo para imunizr um indivìduo para induzir proteção contra um vìrus de rna não segmentado, sentido negativo, de filamento único, da ordem mononegavirales e para produzir vìrus de rna, molécula de ácido nucleico isolada e composição. |
CA2262500C (en) | 1997-06-04 | 2004-03-16 | The Research Foundation For Microbial Diseases Of Osaka University | Measles virus mutant antigen and gene coding for the same |
EP1064358A2 (en) * | 1998-03-26 | 2001-01-03 | American Cyanamid Company | Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup b |
AU781005B2 (en) * | 1999-11-19 | 2005-04-28 | Daiichi Sankyo Company, Limited | Method for producing cell-fusion type morbillivirus mutant |
US6653069B2 (en) | 2000-01-31 | 2003-11-25 | The Research Foundation For Microbial Diseases Of Osaka University | Method for quality control of an attenuated vericella live vaccine |
AU2000279480B2 (en) * | 2000-02-10 | 2006-08-03 | Daiichi Sankyo Company, Limited | Methods for producing temperature-sensitive morbillivirus |
EP1375512B1 (en) * | 2002-06-20 | 2009-07-22 | Institut Pasteur | Infectious cDNA of an approved vaccine strain of measles virus. Use for immunogenic compositions |
EP1375670B1 (en) | 2002-06-20 | 2013-06-12 | Institut Pasteur | Recombinant measles viruses expressing epitopes of antigens of RNA viruses and use of the recombinant viruses for the preparation of vaccine compositions |
CA2432738A1 (en) | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
EP2420242A1 (en) | 2010-08-20 | 2012-02-22 | Lauer, Ulrich M. | Oncolytic measles virus |
CN104211769B (zh) * | 2013-05-30 | 2018-08-03 | 中国科学院过程工程研究所 | 一种小分子抗体亲和肽及其应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4617261A (en) * | 1984-03-21 | 1986-10-14 | Cetus Corporation | Process for labeling nucleic acids and hybridization probes |
JPS63307827A (ja) * | 1987-06-08 | 1988-12-15 | Kitasato Inst:The | 安定化された生ウイルスワクチンおよびその製造法 |
AU7007491A (en) * | 1990-02-02 | 1991-08-08 | Schweiz. Serum- & Impfinstitut Bern | Cdna corresponding to the genome of negative-strand rna viruses, and process for the production of infectious negative-strand rna viruses |
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1991
- 1991-10-14 JP JP3293625A patent/JP3045581B2/ja not_active Expired - Lifetime
-
1992
- 1992-03-07 KR KR1019920003759A patent/KR950012759B1/ko not_active Expired - Lifetime
- 1992-03-10 ES ES92302004T patent/ES2148164T3/es not_active Expired - Lifetime
- 1992-03-10 AT AT92302004T patent/ATE193726T1/de active
- 1992-03-10 EP EP92302004A patent/EP0540135B1/en not_active Expired - Lifetime
- 1992-03-10 DK DK92302004T patent/DK0540135T3/da active
- 1992-03-10 DE DE69231143T patent/DE69231143T2/de not_active Expired - Lifetime
- 1992-03-10 PT PT92302004T patent/PT540135E/pt unknown
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1994
- 1994-11-25 US US08/348,891 patent/US5654136A/en not_active Expired - Lifetime
-
1997
- 1997-08-04 US US08/905,817 patent/US5824777A/en not_active Expired - Lifetime
-
2000
- 2000-08-30 GR GR20000401965T patent/GR3034278T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP3045581B2 (ja) | 2000-05-29 |
KR950012759B1 (ko) | 1995-10-21 |
EP0540135A2 (en) | 1993-05-05 |
US5824777A (en) | 1998-10-20 |
DE69231143D1 (de) | 2000-07-13 |
US5654136A (en) | 1997-08-05 |
DK0540135T3 (da) | 2000-08-07 |
DE69231143T2 (de) | 2000-10-19 |
ATE193726T1 (de) | 2000-06-15 |
PT540135E (pt) | 2000-11-30 |
GR3034278T3 (en) | 2000-12-29 |
EP0540135A3 (en) | 1993-12-08 |
EP0540135B1 (en) | 2000-06-07 |
ES2148164T3 (es) | 2000-10-16 |
JPH05103665A (ja) | 1993-04-27 |
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