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KR910018419A - 프로필렌과 또 다른 1-알켄의 공중합체 - Google Patents

프로필렌과 또 다른 1-알켄의 공중합체 Download PDF

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Publication number
KR910018419A
KR910018419A KR1019910005425A KR910005425A KR910018419A KR 910018419 A KR910018419 A KR 910018419A KR 1019910005425 A KR1019910005425 A KR 1019910005425A KR 910005425 A KR910005425 A KR 910005425A KR 910018419 A KR910018419 A KR 910018419A
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South Korea
Prior art keywords
alkene
another
copolymer
propylene
partial pressure
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KR1019910005425A
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English (en)
Inventor
케르트 위르겐
쾰레 페터
졸크 랄프
Original Assignee
비텐베르크, 바르츠
바스프 악티엔게젤샤프트
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Application filed by 비텐베르크, 바르츠, 바스프 악티엔게젤샤프트 filed Critical 비텐베르크, 바르츠
Publication of KR910018419A publication Critical patent/KR910018419A/ko

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F210/00—Copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
    • A61K47/557—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells the modifying agent being biotin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
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  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)

Abstract

내용 없음

Description

프로필렌과 또 다른 1-알켄의 공중합체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (7)

  1. 전치 압력하에서, 기체 공간에서 단량체 혼합물의 어떠한 축합도 일어나지 않고, 더우기, 프로필렌과 또다른1-알켄의 부분압력 비가 5 : 1 내지 100 : 1로 조절 되도록 온도를 선택하면서, 티탄-함유 고체 성분 이외에, 알루미늄 성분과 전자 공여체를 함유하는 지이글러-나타 촉매계의 도움으로 1내지 5시간이 중합체의 평균 체류 시간을 가지고 60 내지 90℃에서, 15내지 30bar의 압력하에 액체 반응 매질의 부재하에서 프로필렌과 또다른 1-알켄의 혼합물의 기체-상 중합에 의해 얻을 수 있는, 프로필렌과 또다른 1-알켄의 공중합체.
  2. 제1항에 있어서, 상기 방법에서 프로팰렌과 또다른 1-알켄의 부분 압력 비를 5;1 내지50:1로 조절함으로써 얻을 수 있는 것을 특징으로 하는 공중합체.
  3. 제1 또는 2항에 있어서, 상기 방법에서 1-알켄으로서 에틸렌을 사용함으로써 얻을 수 있는 것을 특징으로 하는 공중합체.
  4. 제1또는 2항에 있어서, 상기 방법에서 1-알켄으로서 1-부텐을 사용함으로서 얻을 수 있는 것을 특징으로 하는 공중합체.
  5. 제1 또는 2항에 있어서, 상기 방법에서 에틸렌과 C4-C10-1-알켄의 혼합물들을 사용하고 에틸렌과 C4-C10-1-알켄 사이의 부분 압력비를 1 ; 1내지 100 : 1로 조절함으로써 얻을 수 있는 것을 특징으로 하는 공중합체.
  6. 전치차 압력하에, 기체 공간에서 단량체 혼합물의 어떠한 축합도 일어나지 않고, 더우기, 프로필렌과 또다른 1-알켄의 부분 압력비가 5 : 1 내지 100 : 1로 조절되도록 온도를 선택하는 것으로 이루어지는, 티탄-함유고체 성분 이외에 알루미늄 성분과 전자 공여체를 함유하는 지이글러-나타 촉매계의 도움으로, 1 내지 5시간의 중합체의 체류시간을 가지고 60 내지 90℃에서, 15 내지 30bar의 압력하에 액체 반응 매질의 부재하에서 프로필렌과 또다른 1-알켄의 혼합물의 기체-상 중합을 일으키는, 교반된 고정층에서 프로필렌과 또다른 1-알켄의 공중합체를 제조하는 방법.
  7. 제1 내지 5항중 어느 한 항에 따르는 공중합체로 이루어진 시트 또는 성형품.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910005425A 1990-04-06 1991-04-04 프로필렌과 또 다른 1-알켄의 공중합체 KR910018419A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4011601 1990-04-10
DE4011601A DE4011601A1 (de) 1990-04-10 1990-04-10 Hapten-biotin-konjugate und ihre verwendung

Publications (1)

Publication Number Publication Date
KR910018419A true KR910018419A (ko) 1991-11-30

Family

ID=6404148

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KR1019910005425A KR910018419A (ko) 1990-04-06 1991-04-04 프로필렌과 또 다른 1-알켄의 공중합체

Country Status (8)

Country Link
US (1) US5219764A (ko)
EP (1) EP0451810B1 (ko)
JP (1) JPH082910B2 (ko)
KR (1) KR910018419A (ko)
AT (1) ATE126595T1 (ko)
DE (2) DE4011601A1 (ko)
DK (1) DK0451810T3 (ko)
ES (1) ES2077101T3 (ko)

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DE4239429A1 (de) * 1992-11-24 1994-05-26 Merck Patent Gmbh Verfahren zur Herstellung von Immunkonjugaten
AU670674B2 (en) * 1993-01-06 1996-07-25 Beckman Instruments, Inc. Method for making a preconjugate
US5536820A (en) * 1993-02-26 1996-07-16 E. I. Du Pont De Nemours And Company Avidin-binding azo reagents
EP0640836A3 (en) * 1993-08-24 1995-12-20 Wako Pure Chem Ind Ltd Immunoassay.
US5527711A (en) * 1993-12-13 1996-06-18 Hewlett Packard Company Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques
US5747352A (en) * 1994-05-23 1998-05-05 Beckman Instruments, Inc. Reagents and methods for the rapid and quantitative assay of pharmacological agents
US5716594A (en) * 1994-06-06 1998-02-10 The Jmde Trust Biotin compounds for targetting tumors and sites of infection
DE69533105T2 (de) * 1994-06-06 2005-06-09 The Jmde Trust, Newton Biotinverbindungen zum zielen auf tumore und infektionsherde
JP3260379B2 (ja) † 1995-12-29 2002-02-25 ビオテッツ ベルリン―ブッフ ゲーエムベーハー 西洋ワサビペルオキシダーゼを用いて生体分子を標識する方法
DE19748489A1 (de) 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
US6326479B1 (en) 1998-01-27 2001-12-04 Boston Probes, Inc. Synthetic polymers and methods, kits or compositions for modulating the solubility of same
US6153442A (en) * 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
JP2002296281A (ja) * 2001-03-07 2002-10-09 F Hoffmann La Roche Ag 改良された均一系イムノアッセイ法
US7145019B2 (en) * 2003-10-16 2006-12-05 Ambergen, Inc. Photocleavable isotope-coded affinity tags
WO2007112079A2 (en) * 2006-03-24 2007-10-04 Duke University Multivalent immunogen
JP2010053118A (ja) * 2008-07-28 2010-03-11 Fujifilm Corp ビオチン化チロキシン
CN113721012B (zh) * 2021-08-27 2022-08-09 深圳上泰生物工程有限公司 一种组合物及其试剂盒在检测甘胆酸中的用途
CN118265723A (zh) 2021-11-11 2024-06-28 豪夫迈·罗氏有限公司 针对l-甲状腺素的新颖单克隆抗体及其诊断用途

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US4617261A (en) * 1984-03-21 1986-10-14 Cetus Corporation Process for labeling nucleic acids and hybridization probes
NZ211453A (en) * 1984-03-22 1989-01-06 Biotechnology Research Enterpr Aryl azides, their preparation and use in the detection, localisation and isolation of polynucleotides
US4760142A (en) * 1984-11-27 1988-07-26 Hoechst Celanese Corporation Divalent hapten derivatives
EP0183901B1 (de) * 1984-11-27 1992-07-08 BEHRINGWERKE Aktiengesellschaft Bifunktionelle Haptene, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0310361A3 (en) * 1987-09-30 1989-05-24 Beckman Instruments, Inc. Tridentate conjugate and method of use thereof
ES2056936T3 (es) * 1987-09-30 1994-10-16 Beckman Instruments Inc Conjugado bidentado y metodo de utilizacion del mismo.
DE3822750A1 (de) * 1988-07-05 1990-01-11 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz

Also Published As

Publication number Publication date
ATE126595T1 (de) 1995-09-15
US5219764A (en) 1993-06-15
EP0451810A1 (de) 1991-10-16
JPH082910B2 (ja) 1996-01-17
ES2077101T3 (es) 1995-11-16
EP0451810B1 (de) 1995-08-16
JPH04224583A (ja) 1992-08-13
DK0451810T3 (da) 1996-01-02
DE4011601A1 (de) 1991-10-17
DE59106246D1 (de) 1995-09-21

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