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KR870003793A - 트롬빈 제재의 방법 - Google Patents

트롬빈 제재의 방법 Download PDF

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Publication number
KR870003793A
KR870003793A KR1019860008973A KR860008973A KR870003793A KR 870003793 A KR870003793 A KR 870003793A KR 1019860008973 A KR1019860008973 A KR 1019860008973A KR 860008973 A KR860008973 A KR 860008973A KR 870003793 A KR870003793 A KR 870003793A
Authority
KR
South Korea
Prior art keywords
thrombin
preparation
sanctions
buffer
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
KR1019860008973A
Other languages
English (en)
Inventor
비. 실버링 스트븐
유. 네스비트 러셀
비. 파우지 매디
Original Assignee
스테펜 라인스
워너-램버트 컴패니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25154936&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR870003793(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 스테펜 라인스, 워너-램버트 컴패니 filed Critical 스테펜 라인스
Publication of KR870003793A publication Critical patent/KR870003793A/ko
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/22—Blood coagulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

내용 없음

Description

트롬빈 제재의 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 생성물의 최종 pH가 약 5.0 내지 약 6.0이 되도록, 트롬빈을 자기분해 방지량과 접촉시키는 단계로 구성되는 안정화된 제제를 포함하는 생성물을 제조하는 방법.
  2. 제1항에 있어서, 최종 pH가 약 5.3인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860008973A 1985-10-28 1986-10-27 트롬빈 제재의 방법 Abandoned KR870003793A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/791,836 US4696812A (en) 1985-10-28 1985-10-28 Thrombin preparations
US791.836 1985-10-28

Publications (1)

Publication Number Publication Date
KR870003793A true KR870003793A (ko) 1987-05-04

Family

ID=25154936

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860008973A Abandoned KR870003793A (ko) 1985-10-28 1986-10-27 트롬빈 제재의 방법

Country Status (14)

Country Link
US (1) US4696812A (ko)
EP (1) EP0221700B1 (ko)
JP (1) JPH0764747B2 (ko)
KR (1) KR870003793A (ko)
AT (1) ATE83927T1 (ko)
AU (1) AU586897B2 (ko)
CA (1) CA1272128A (ko)
DE (1) DE3687402T2 (ko)
DK (1) DK512686A (ko)
ES (1) ES2053442T3 (ko)
GR (1) GR3006727T3 (ko)
NZ (1) NZ217190A (ko)
PH (1) PH23444A (ko)
ZA (1) ZA868223B (ko)

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ZA88227B (en) * 1987-01-28 1988-06-30 Warner-Lambert Company Thrombin preparations
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JP2715104B2 (ja) * 1988-08-18 1998-02-18 株式会社ミドリ十字 トロンビン乾燥製剤
US4891359A (en) * 1988-12-08 1990-01-02 Johnson & Johnson Patient Care, Inc. Hemostatic collagen paste composition
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US5219328A (en) * 1990-01-03 1993-06-15 Cryolife, Inc. Fibrin sealant delivery method
US5318524A (en) * 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
IE73210B1 (en) * 1990-01-24 1997-05-07 Warner Lambert Co Process for the production of thrombin and high purity thrombin preparation thereby obtained
JPH0813750B2 (ja) * 1990-03-01 1996-02-14 持田製薬株式会社 経口用トロンビン製剤
US5595735A (en) * 1990-05-23 1997-01-21 Johnson & Johnson Medical, Inc. Hemostatic thrombin paste composition
ATE143411T1 (de) * 1991-03-28 1996-10-15 Warner Lambert Co Hochreine thrombinzubereitung
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JP3230713B2 (ja) * 1992-10-23 2001-11-19 トヨタ自動車株式会社 ピークトルク低減機構
US5795780A (en) * 1993-06-23 1998-08-18 Bristol-Myers Squibb Company Method of use of autologous thrombin blood fraction in a cell culture with keratinocytes
US5506127A (en) * 1994-09-21 1996-04-09 Proba; Zbigniew Therapeutic grade thrombin produced by chromatography
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JP3401162B2 (ja) * 1996-11-21 2003-04-28 積水化学工業株式会社 血液凝固促進剤及び血液検査用容器
JP3927403B2 (ja) * 1996-11-21 2007-06-06 積水化学工業株式会社 血液凝固促進剤及び血液検査用容器
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
US6472162B1 (en) 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
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DE10012732A1 (de) * 2000-03-18 2001-09-20 Aventis Behring Gmbh Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung
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US7923431B2 (en) 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
BR0317237A (pt) 2002-12-11 2005-11-01 Ferrosan As Dispositivo para amostragem ou coleta, kit, usos de um dispositivo e de um kit, e, métodos para diminuir a quantidade de um marcador em uma área de amostra, para amostrar de modo qualitativo ou quantitativo uma área quanto ao teor de um marcador e para cultivar microorganismos ou células de mamìferos coletados
US20040243044A1 (en) * 2003-06-02 2004-12-02 Penegor Stephen A. Hemostatic wound dressing
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
EP1713521B1 (en) 2004-01-30 2010-07-28 Ferrosan A/S Haemostatic sprays and compositions
ES2313383T3 (es) * 2004-06-22 2009-03-01 Zymogenetics, Inc. Composiciones de trombina.
RU2369408C2 (ru) 2004-07-09 2009-10-10 Ферросан А/С Гемостатическая композиция, включающая гиалуроновую кислоту
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Also Published As

Publication number Publication date
NZ217190A (en) 1989-05-29
CA1272128A (en) 1990-07-31
EP0221700A2 (en) 1987-05-13
ATE83927T1 (de) 1993-01-15
DE3687402D1 (de) 1993-02-11
EP0221700B1 (en) 1992-12-30
PH23444A (en) 1989-08-07
JPH0764747B2 (ja) 1995-07-12
DK512686D0 (da) 1986-10-27
GR3006727T3 (ko) 1993-06-30
AU6451786A (en) 1987-04-30
DK512686A (da) 1987-04-29
AU586897B2 (en) 1989-07-27
ZA868223B (en) 1987-07-29
JPS62106028A (ja) 1987-05-16
US4696812A (en) 1987-09-29
EP0221700A3 (en) 1987-08-26
ES2053442T3 (es) 1994-08-01
DE3687402T2 (de) 1993-05-06

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Patent event code: PA01091R01D

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Patent event date: 19861027

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Patent event date: 19911026

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Patent event code: PE09021S01D

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