KR102119316B1 - Cosmetic composition containing Paeonia suffruticosa complex extract - Google Patents

Abstract

The present invention relates to a cosmetic composition containing a complex extract of peony flowers, sseonhwa, pearls, persimmons, motherwort, sunbokhwa, yulmu and motherwort, and the complex extract as an active ingredient is made of natural extracts and has little side effects and irritation to skin. Excellent anti-acid, anti-inflammatory, anti-wrinkle and whitening effect.

Description

Cosmetic composition containing a peony complex extract {Cosmetic composition containing Paeonia suffruticosa complex extract}

The present invention relates to a cosmetic composition containing a complex peony extract, specifically, contains a complex extract of peony flowers, ssoonhwa, pearls, persimmons, caps, sunbokhwa, yulmu and motherwort as an active ingredient, antioxidant, anti-inflammatory, wrinkles It relates to a cosmetic composition excellent in improving and whitening activity.

Recently, interest in cosmetics derived from natural products is growing. In addition, as the demand for functional cosmetics increases, there is a problem in that the protective or regenerating ability of the skin is deteriorated due to various chemical components used as functional ingredients. Accordingly, it is popular to make and use cosmetics made from natural materials, including skins, lotions, and color cosmetics. In the case of people with skin diseases such as atopy or sensitive skin, interest in cosmetics derived from natural products having excellent skin improvement activity while minimizing skin irritation is increasing.

Peony (Paeonia suffruticosa) is a deciduous tree belonging to the family Asteraceae. Also called Mokdan, it grows about 2m in height and has thick, hairless branches. Leaves are alternate, 2 times upper right biplane, and lobule is divided into two or three again, and there is no hair on the surface. Flowers bloom in May, are benign, have a diameter of 15 cm or more, and are reddish purple, but are white, red, pink, scarlet, deep red, purple, and yellow. There are 5 to 7 petals, but varieties with many petals running have been developed. The flowering period is 2 to 3 days, but many petals bloom 7 to 10 days. The bark of the root has the efficacy of antipyretic, analgesic, jinkyung (鎭痙), gueohyeol (驅瘀血), tongyeong (通經), yanghyeol (凉血), anti-inflammatory (消炎) and is used as a medicine. Yakseong is positive and declaring. Hyperthermia of various febrile diseases, sensitizing fever, span and various blood circulation disorders, menstrual disorders, menopause, vaginal damage, ongjong, etc. Take it as a pill or powder.

Traditionally, peony flower or peony flower, which is a medicine made from the root skin of peonies, has been widely used as a raw material for anti-oxidation, anti-wrinkle, anti-inflammatory, and whitening cosmetics due to its skin improvement activity.

Republic of Korea Patent Publication No. 2011-0001538 "flower mixed extract having antioxidant and whitening activity and a method for extracting it and a cosmetic composition containing the flower mixed extract" "flower mixed extract containing peony flower has antioxidant and whitening activity" In the Republic of Korea Patent Registration No. 1485104, "Cosmetic composition containing herbal extracts," it is disclosed that the'mokdanpi extract has excellent antioxidant and anti-inflammatory effects'.

The present inventors have researched various natural products having skin improvement activity, and when using peony flower as a complex extract with snail, pearl, persimmon, cap, pear, yulmu and motherwort, more excellent antioxidant, anti-inflammatory, wrinkle improvement and whitening The present invention was completed by confirming that it has activity.

An object of the present invention is to provide a cosmetic composition exhibiting excellent antioxidant, anti-inflammatory, anti-wrinkle and whitening activity by containing a complex extract of peony flowers, sseonhwa, pearls, persimmons, motherwort, sunbokhwa, yulmu and motherwort .

According to the present invention to achieve the above object, there is provided a cosmetic composition containing a complex extract of peony flowers, sseonhwa, pearls, persimmons, caps, sunbokhwa, yulmu and motherwort.

The complex extract is a peony flower, sseonhwa, pearl, persimmon, hat half, sunbok, yulmu and motherwort, then hot water extracted or water, lower alcohol having 1 to 4 carbon atoms, ethyl acetate, glycerin, ethylene glycol, propylene glycol And it is prepared by extraction with at least one solvent selected from the group consisting of butylene glycol.

The complex extract is peony flower, sseonhwa, pearls, persimmon, hat half, sunbokhwa, Yulmu and motherwort, respectively 1~2: 1~2: 1~2: 1~2: 1~2: 1~2 : It is extracted after mixing at a weight ratio of 1 to 2.

The composite extract is contained in an amount of 0.01 to 10% by weight based on the total weight of the cosmetic composition.

The cosmetic composition may be used for antioxidant, anti-inflammatory, wrinkle improvement or whitening.

The peony flower, perennial, pearl, persimmon, motherwort, sunbokhwa, yulmu and motherwort complex extracts made of natural extracts have less side effects and less skin irritation and exhibit excellent antioxidant, anti-inflammatory, anti-wrinkle and whitening activity. It can be useful.

1 is a graph showing the cell viability of a composite extract according to an embodiment of the present invention.
Figure 2 is a graph showing the NO assay results of the complex extract according to an embodiment of the present invention.
3 is a graph showing the results of the MMP-1 assay of the complex extract according to an embodiment of the present invention.
4 is a graph showing the results of a Procollagen assay of a complex extract according to an embodiment of the present invention.
5 is a graph showing the effect of inhibiting the melanan complex extract according to an embodiment of the present invention.

Hereinafter, the present invention will be described in more detail.

The present invention relates to a cosmetic composition containing a complex extract of eight natural products including peony flowers as an active ingredient.

One of the raw materials constituting the complex extract of the present invention, Adonis amurensis, is a perennial plant of the family Asteraceae, Asteraceae, Asteraceae. It is also referred to as Wonilcho and Vengeance. It grows in the shade in a mountainous forest. It is 10-30cm in height. The rootstock is short, thick, and has many dark brown roots. The stem splits from the upper part, and there is no hair or the lower leaf is membranous and surrounds the main stem. The leaves have no hairs on both sides or small hairs on the back, and there are no leaf bodies at the bottom, only the bottom, and they are shifted upward and split into fine feathers. Flowers bloom in early April, yellow, 3-4cm in diameter, hanging one at the end of the main stem and branch. The calyx pieces are dark green, several petals are spread horizontally, 20-30 petals, there are many stamens, and the anther is 1-2mm long. The fruit is a fruit tree and runs on a flower jaw about 1 cm long and has hairs that go into a ball shape. It is used as an analgesic, changjong, gangsimje (强心劑), and a diuretic in oriental medicine and the private sector. In the present invention, the outpost or flower of ssoonhwa is used.

Pearl refers to a bead-like or hemispherical shiny glandular secretion composed mainly of calcium carbonate formed in the body of mollusk tribe shellfish. Pearl is widely used as a dietary supplement or as a beauty ingredient for skin because it is effective in detoxification, sedative action, and skin diseases, paralysis, and cramping. In particular, pearl powder is a calcium source useful for adults, and it is known that ingestion of pearlized nanoparticles is rapidly absorbed into the body and used, and when used on the skin, it suppresses aging and maintains the skin weakly acid to increase skin immunity.

Ecklonia cava is a perennial seaweed with brown seaweed kelp tree seaweed. It grows deep in the lunch table. The stem is cylindrical and the base is root-shaped. The middle part is thick and full of the stomach when you are young, but the stomach is empty after it has grown. It is an important algae plant that makes up seaweed and mainly feeds abalone and conch. It is the main raw material for making alginic acid, iodine, and potassium, and is also used for edible purposes.

Sargassum fulvellum is the seahorse of the brown algae capsicum cap. It grows under the intertidal zone. It is also commonly used as a term for a large brown algae belonging to the mother-family. The body is apparently distinct from the roots, stems, and leaves, and the roots are gaban-shaped and grow out larger than 1~3m by cutting out one central branch. The stem is triangular columnar or triangular and twisted. The leaves are curved toward the base from the stem, curved, and have a spatula shape or oval shape, and the middle part of the leaf is formed. The upper leaves are lanceolate and have serrated projections on the edges, and air bubbles are formed from the stems all over the body. Many types of caps are also edible, and are used as raw materials in the seaweed industry such as alginic acid or as fertilizer.

Seonbokhwa (旋覆花) is a medicinal herb that dried the flowers of the Asteraceae (Inula britannica var. japonica (Thunb.) Franch. & Sav). As a pharmacological action, anticonvulsant action and diuretic action of the bronchus were reported. Appearance is either spheroidal or spherical and consists of several guns arranged in a tile shape. The pieces of the gun are small, scaly and grayish-yellow. At the bottom of the gun, there are traces of calyx, and the fragments of the gun and the outer surface of the calyx are covered with white fur. There are many white hairs at the end of ovary and the length is about 5mm. Here is a small oval seed.

Yulmu (Coix lachrymajobi var. mayuen) is an annual plant of the monocotyledonous plant. It grows to 1~1.5m, has a hard inside, and grows straight and branches are split. The leaves are alternate, lanceolate, and the butterfly is about 2.5cm, and the lower part becomes the leaf sheath. Flowers bloom in July-September, and 3cm long male hairs hang at the end of the flower ear from the leaf axil. There is a female ear wrapped in an oval leaf house at the bottom. The fore is hard, elliptical, about 1.2 cm long, and ripens into a blackish brown. When the ovary matures, the leaf sheath becomes hard and becomes dark brown. Fruits are nuts and ripen in October. Breeding is done with seeds. It is a naturalized plant native to China and cultivated as a medicinal crop. The seeds are called Ui-in (인仁), so they are eaten with tea or used as medicines for edema, neuralgia, rheumatism, and bladder stones because they have diuretic, analgesic, analgesic, and tonic effects. Raw leaves are used as tea substitutes, and roots are used for jaundice and neuralgia. Leaves on the stem are also used as feed. In the present invention, the fruit of Yulmu is used.

The motherwort (Leonurus japonicus Houtt.) is a biennial plant of the dicotyledonous plant, the honeydew. It grows in the field and is about 1m high. The branches are split, the stem cross section is dull square, and white hairs appear white and green. The leaves face each other, and the leaves attached to the roots are egg-shaped, circular, and there are dull marks, and the leaves attached to the stem are divided into three. The forked pieces are feathers, divided into 2-3 pieces again, and have serrated teeth. Flowers bloom light red-purple in July-August, 6-7mm long, and run in layers at nodes. The hawk is a small nut and has a wide egg shape and ripens in September to October and is in the calyx. Seeds have 3 ridges and are 2~2.5mm long. Dry the entire bag and use it for postpartum hemostasis and abdominal pain. In the present invention, the outpost, stem or leaf of motherwort is used.

According to one embodiment of the present invention, the peony flower, sseonhwa, pearls, persimmons, caps, sunbokhwa, yulmu and motherwort complex extracts are prepared by the following method. First, a mixture is prepared by mixing washed and dried peony flowers, sseonhwa, pearl powder, persimmon, cap, bokbok, yulmu and motherwort. Subsequently, the mixture is extracted with hot water or extracted with at least one solvent selected from the group consisting of water, lower alcohol having 1 to 4 carbon atoms, ethyl acetate, glycerin, ethylene glycol, propylene glycol, and butylene glycol. Extraction can be performed according to a conventional method.

Preferably, the complex extract is peony flower, sseonhwa, pearls, persimmons, caps, bokbok, yulmu, and motherwort, respectively 1~2: 1~2: 1~2: 1~2: 1~2: 1~2: 1~2: It may be extracted after mixing at a weight ratio of 1~2, or after preparing each extract and mixing each at the above ratio. Most preferably, it is made by mixing at a weight ratio of 1:1:2:1:2:1:1:1.

The composite extract is contained in an amount of 0.01 to 10% by weight based on the total weight of the cosmetic composition.

Compared to the case where only the peony flower extract is used as the active ingredient, the peony flower, snow lily, pearl, persimmon, cap, bokbok, yulmu and motherwort complex extracts have a superior antioxidant effect, anti-inflammatory effect, and wrinkles due to their synergy. It was confirmed that it shows an improvement effect and a whitening effect. Therefore, the cosmetic composition containing it as an active ingredient can be used as an antioxidant, anti-inflammatory, wrinkle improvement or whitening cosmetics.

The cosmetic composition of the present invention can be prepared in any conventional formulation, for example, lotion, cream, essence, cleansing foam, cleansing water, pack, body lotion, body oil, body gel, shampoo, rinse, hair Conditioners, hair gels, foundations, lipsticks, mascaras, and makeup bases.

[Example]

Hereinafter, the present invention will be described in detail through the following examples and test examples, but the present invention is not limited by these examples.

Preparation Example 1: Preparation of peony flower extract

After washing and drying the peony flowers, extraction and filtration were repeated 3 times at room temperature for 5 days using 70% ethanol 10 times by weight, all of them were collected and concentrated under reduced pressure to obtain a concentrated solution of about 12 g.

Preparation Example 2: Preparation of the extract of sseonhwa

To extract the flower of the snow lily was prepared in the same manner as in Preparation Example 1, to prepare a snow lily flower extract.

Preparation Example 3: Preparation of pearl extract

After pulverizing the pearl grains, the powder filtered with 200 mesh was extracted in the same manner as in Preparation Example 1 to prepare a pearl extract.

Preparation Example 4: Preparation of persimmon extract

Persimmon extract was prepared in the same manner as in Preparation Example 1 to prepare persimmon extract.

Preparation Example 5: Preparation of capsicum extract

The extract was prepared in the same manner as in Preparation Example 1 to prepare the extract.

Preparation Example 6: Preparation of Sunbokhwa extract

The bokbok extract was extracted in the same manner as in Preparation Example 1 to prepare a bokbok extract.

Preparation Example 7: Preparation of Yulmu extract

Yulmu fruit was extracted in the same manner as in Preparation Example 1 to prepare Yulmu extract.

Preparation Example 8: Preparation of motherwort extract

Motherwort outpost was extracted in the same manner as in Preparation Example 1 to prepare motherwort extract.

Example 1: Preparation of a complex peony extract

10 g of peony flowers, 10 g of snow lily, 20 g of pearl powder, 10 g of persimmon, 20 g of capwort, 10 g of sunbokhwa, 10 g of Yulmu and 20 g of motherwort. The mixture was extracted and filtered at room temperature for 5 days using 70% ethanol 10 times the weight of the mixture for 3 times, and all of them were collected and concentrated under reduced pressure to prepare a peony complex extract.

Examples 2 to 4: Preparation of the complex extract of peonies

Peony flowers, sseonhwa, pearl powder, persimmon, hat half, sunbokhwa, yulmu and motherwort were changed to the weight of Table 1 to prepare a peony composite extract in the same manner as in Example 1.

Weight ratio Peony flower Snowflakes Pearl Feeling Hat half Sunbokhwa Yulmu motherwort Example 2 One One One One One One One One Example 3 One 2 One 2 2 One 2 One Example 4 2 2 One 2 2 One 2 2

Comparative Example 1: Preparation of complex extract without peony

10 g of ssoonhwa, 20 g of pearls, 10 g of persimmon, 20 g of caps, 10 g of sunbokhwa, 10 g of Yulmu and 20 g of motherwort were mixed. The mixture was extracted and filtered at room temperature for 5 days using 70% ethanol 10 times the weight of the mixture three times, and then all of them were collected and concentrated under reduced pressure to prepare a peony complex extract.

Test Example 1: Antioxidant activity test

In order to evaluate the antioxidant activity, a free radical scavenging effect assay for DPPH radicals using the extracts of Preparation Examples, Comparative Examples and Examples was performed in the following manner.

DPPH was purchased and used by Sigma Co., Ltd. (USA). First, a standard DPPH solution of 400 μm concentration was made. Then, in Examples 2 to 4 and Comparative Examples, ethanol was added to prepare samples at a concentration of 200 µg/ml. Then, the sample and the standard DPPH solution were added at the same rate, stirred well, reacted at 37°C for 30 minutes, and absorbance was measured at 520 nm. The free radical scavenging rate (%) was calculated using the following equation, and the EC50 value representing 50% free radical scavenging activity was calculated and the results are shown in Table 2 below.

Ascorbic acid (100ppm) was used as a control, and as a comparative example 2, peony oil (oil extracted by squeezing peony seeds) was used.

Free radical scavenging rate (%)=100-(reaction absorbance of sample/reaction absorbance of control) × 100

division EC50 Preparation Example 1 4.364 Preparation Example 2 6890 Preparation Example 3 7173 Preparation Example 4 8942 Preparation Example 5 6236 Preparation Example 6 5569 Preparation Example 7 1055 Preparation Example 8 8842 Comparative Example 1 8674 Comparative Example 2 9.449 Example 1 1.288 Example 2 12.36 Example 3 15.88 Example 4 18.32

As shown in Table 2, the anti-oxidant effect was confirmed in the peony flower extract of Preparation Example 1, the peony oil of Comparative Example 2, and the peony complex extract of Example. Antioxidant activity was not observed in the extracts of Preparation Examples 2 to 8 or the composite extract of Comparative Example 1 except for the peony flower, but it was confirmed that excellent antioxidant activity was exhibited in the complex extract of the example of the present invention containing the peony flower. The best antioxidant activity was found in the complex extract of Example 1.

Test Example 2: Confirmation of cell proliferation

Cell viability assay was performed on the extracts of Preparation Example 1, Comparative Example 1 and Example 1 in the following manner.

First, human fibroblast cells were inoculated in a 96-well plate (96 well plate, Corning) and cultured, and then Comparative Example 1, Example 1 and Preparation Example 1 were applied for each concentration for 2 days, and the MTT test was performed. The method was performed to evaluate cell proliferation. Serum-free medium was used as a control.

Cell viability was calculated according to the following formula and the results are shown in FIG. 1.

Cell viability (%) = (absorbance of each sample) / (control absorbance) × 100

As can be seen in Figure 1, it can be seen that the cell proliferation (Cell proliferation) by concentration in the peony complex extract of Example 1.

Test Example 3: anti-inflammatory activity confirmation (NO assay)

The anti-inflammatory activity was evaluated for the extracts of Preparation Example 1, Comparative Example 1 and Example 1 in the following manner.

First, the macrophage cell line RAW 246.7 cells using 10% Fetal bovine serum (FBS), 1% Penicillin/streptomycin (P/S) containing Dulveccos's modified eagles medium (DMEM) medium at 37 ℃, 5% CO ₂ conditions It was cultured in a constant temperature incubator. Cells were treated with 6×10 ⁴ cells per well in a 48-well culture plate and cultured for 24 hours. After incubation, treatment was performed with Preparation Example 1, Comparative Example 1, and Example 1 diluted to concentrations (5, 100, 200 μg/mL), and after 1 hour, Lipo poly saccharide (LPS) was treated in each well at a concentration of 1 μg/mL. After that, the cells were further cultured for 22 hours. When culture is complete, mix 100 μL of cell culture solution and 100 μL of Griess reagent [1% (w/v) sulfanilamide, 0.1% N-1-napthylethylene diamine in 2.5% (w/v) phosphoric acid] for 10 minutes in a 96 well plate. After the reaction, absorbance was measured at 540 nm. A standard curve was obtained using sodium nitrate, and the resulting nitrite value was calculated, and the results are shown in FIG. 2.

As can be seen in Figure 2, although the anti-inflammatory activity can be confirmed in the peony extract of Preparation Example 1 and the peony extract of Comparative Example 1, it showed better anti-inflammatory activity in the peony composite extract of Example 1 of the present invention. It can be seen that the peony complex extract of Example 1 is significantly decreased in a concentration-dependent manner.

Test Example 4: MMP-1 Assay

Wrinkle improvement activity of the extracts of Preparation Example 1, Comparative Example 1 and Example 1 was evaluated in the following manner.

Human-derived fibroblasts (human fibroblast cells) were inoculated into 24-well plates at a concentration of 5×10 ⁴ cells/well and stabilized in an incubator at 37° C. and 5% CO ₂ conditions for 24 hours. Thereafter, the cells were rinsed twice with PBS, removed, and exchanged with a culture medium to which 0.2% FBS was added, and the extracts of Preparation Example 1, Comparative Example 1 and Example 1 were treated for 48 hours for each cell. After 48 hours, only the supernatant was obtained and the absorbance was measured at a wavelength of 450 nm with a spectrophotometer using a human total MMP-1 ELISA kit (human total MMP-1 Cat.no.DY901, R&D systems). It is shown in 3.

As can be seen in Figure 3, although it can be seen that the concentration-dependent MMP-1 expression is also reduced in the peony extract of Preparation Example 1, it can be seen that the expression is significantly reduced in the peony complex extract of Example 1. As a result, excellent wrinkle improvement activity of the peony composite extract of Example 1 can be confirmed.

Test Example 5: Procollagen Assay

Wrinkle improvement activity of the extracts of Preparation Example 1, Comparative Example 1 and Example 1 was evaluated in the following manner.

The extracts of Preparation Example 1, Comparative Example 1 and Example 1 were added to the culture medium of human-derived fibroblasts, and cultured for 1 day. Then, the culture solution was taken and collagen was synthesized at each concentration with PICP EIA Kit. The degree was measured at 450 nm using a spectrophotometer. At this time, the collagen synthesis degree was measured in the same way for the sample to which the culture medium (control) of fibroblasts to which nothing was added was added for comparison of effects, and the results are shown in FIG. 4.

As can be seen in Figure 4, unlike other samples, it can be seen that the peony complex extract of Example 1 significantly increases Procollagen expression at a concentration of 1%.

Test Example 6: Whitening activity confirmation

The whitening activity of the extracts of Preparation Example 1, Comparative Example 1 and Example 1 was evaluated in the following manner.

First, the extracts of Preparation Example 1, Comparative Example 1 and Example 1 were added to the medium of malignant melanin tumor cells (B-16 mouse melanoma cell) together with aqueous hydroquinone solution, and cultured for 3 days, followed by treatment with trypsin. Cells were removed from the culture vessel and centrifuged to extract melanin. To this, 1 ml of sodium hydroxide solution (1 N concentration) was added, boiled for 10 minutes to dissolve melanin, and the absorbance at 400 nm was measured using a spectrophotometer to measure the amount of melanin produced as absorbance per unit cell. The experiment was repeated three or more times, and the amount of melanin produced relative to the control was calculated as the inhibition rate (%), and the results are shown in FIG. 5.

As can be seen in Figure 5, it can be seen that the peony extract of Preparation Example 1 does not affect melanogenesis, and in the complex extract except for the peony of Comparative Example 1, the melanogenesis increases in a concentration-dependent manner, and the color appears dark. However, unlike other samples, in the case of the peony complex extract of Example 1, melanogenesis was decreased in a concentration-dependent manner.

Formulation Example 1: Preparation of Serum Containing Peony Complex Extract

Serum containing the peony complex extract (Example 1) was prepared according to the conventional method with the composition and content of Table 3 below.

Raw material Content (% by weight) Peony complex extract (Example 1) 1.0 Wax 1.0 Polysorbate 60 1.5 Sorbitan sesquioleate 0.5 Mineral oil 10.0 Sorbitan stearate 0.5 Lipophilic monostearate glycerin 1.0 Stearic acid 1.5 Glyceryl stearate/page-400 stearate 1.0 Propylene glycol 3.0 Carboxy polymer 0.1 Triethanolamine 0.1 Phenoxyethanol Proper Purified water To 100

Formulation Example 2: Preparation of a cream containing a complex extract

The cream containing the peony complex extract (Example 1) was prepared according to the conventional method with the composition and content of Table 4 below.

Raw material Content (% by weight) Peony complex extract (Example 1) 1.0 Shea butter 2.0 Polysorbate 60 1.5 Sorbitan sesquioleate 0.8 Mineral oil 10.0 Dimethicone 3.0 Sorbitan stearate 0.5 Lipophilic monostearate glycerin 1.0 Cetearyl alcohol 2.0 Glyceryl stearate/PG??400 stearate 1.0 Propylene glycol 3.0 Carboxy polymer 0.25 Triethanolamine 0.25 Phenoxyethanol Proper Purified water To 100

Test Example 7: Confirmation of formulation stability

For the formulations prepared in Examples 1 and 2 of the above formulations, they are stored in an opaque vial container in a room, refrigerator and incubator kept constant at room temperature (25°C), refrigeration (4°C) and constant temperature (50°C) and stored for 12 weeks. And observation (discoloration, odor and separation), and stability was confirmed. Table 5 shows the results.

Temperature condition Stability check (discoloration, odor and separation) Formulation Example 1 Formulation Example 2 Room temperature (25℃) 0 0 Refrigeration (4℃) 0 0 Constant temperature (50℃) 0 0

<Formulation stability grade>

0: No change 1: Minor change 2: Change 3: Severe change

As shown in the above table, it was confirmed that both the formulation examples 1 and 2 formulations were stable without discoloration, odor and separation under 25°C, 4°C and 50°C temperature conditions.

Claims (7)

Peony flower, snow lily, pearl, persimmon, mother-of-pearl, sunbokhwa, yulmu, and motherwort, respectively, mixed in a weight ratio of 1: 1: 2: 1: 2: 1: 1, and then extracted peony flower, snow lily, pearl, persimmon , Mojangban, sunbokhwa, Yulmu and cosmetic composition containing a complex extract of motherwort. delete delete According to claim 1, The composite extract is a cosmetic composition characterized in that it is contained in an amount of 0.01 to 10% by weight relative to the total weight of the cosmetic composition. delete The cosmetic composition according to claim 1, wherein the cosmetic composition is for wrinkle improvement. The cosmetic composition according to claim 1, wherein the cosmetic composition is used for whitening.

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