JPS6129322B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to shampoo compositions. Shampoo is a hair or scalp cleansing agent, and its purpose is to remove sebum, dandruff, and residual hair styling products, and to cleanse the hair and scalp. Shampoo has the highest penetration rate among cosmetics, and is important not only for general households but also for professional use in hairdressers and beauty salons. Conventionally, shampoo has been made mainly from surfactants such as soap, alkylbenzene sulfonates, higher alcohol sulfate ester salts, polyoxyethylene alkyl sulfate ester salts, and amphoteric surfactants, and foaming agents such as fatty acid alkanolamides and foaming agents. Motsutomo (motsutomo) containing a sticky agent and the like is commonly used. However, the cleaning power of such shampoos is so strong that it not only removes dirt from the scalp and hair, but also removes the lipids that protect the scalp and hair, leaving the scalp dry and dry. As a result, it lost its luster, and it also had drawbacks such as difficulty in combing. In order to compensate for these drawbacks, fatty acid ester oils such as myristate isopropyl ester or protein hydrolysates are added to shampoos to prevent excessive degreasing of the scalp and hair, in other words to provide a conditioning effect. It is difficult to say that a sufficient effect is uniformly obtained regardless of the type of treatment. However, as a result of various studies, the present inventors have found that when using a shampoo containing a salt of an acidic amino acid or an N-lower aliphatic acyl sulfur-containing amino acid and a basic amino acid, or a mixture of these salts, there is no difference in hair type. It has been found that a remarkable conditioning effect can be obtained, and it has been found that the dryness of the hair and the ease of combing are significantly improved. That is, the present invention is a shampoo composition containing a salt of an acidic amino acid or an N-lower aliphatic acyl sulfur-containing amino acid and a basic amino acid, or a mixture thereof. In the present invention, examples of the basic amino acid salts of acidic amino acids to be incorporated into the shampoo composition include salts of acidic amino acids such as glutamic acid and aspartic acid with basic amino groups such as histidine, arginine, lysine, and oxylysine. , especially aspartic acid/arginine equimolar salts, aspartic acid/lysine equimolar salts, glutamic acid/
Arginine equimolar salts and glutamic acid/lysine equimolar salts can be suitably used. In addition, basic amino acid salts of N-lower aliphatic acyl sulfur-containing amino acids include N-acetylmethionine, N-acetylcysteine, N-propionylmethionine, N-
Examples include salts of N-lower aliphatic acyl sulfur-containing amino acids such as propionylcysteine, N-butyrylmethionine, N-butyrylcysteine, and N・N'-diacetylcystine and the above basic amino acids, especially N-acetylcysteine. Equimolar salts of basic amino acids of N-lower aliphatic acyl sulfur-containing amino acids such as equimolar salts of methionine/arginine and equimolar N-acetylcysteine/arginine salts can be suitably used. The above-mentioned salts of acidic amino acids or N-lower aliphatic acyl sulfur-containing amino acids and basic amino acids (hereinafter simply referred to as basic amino acid salts) can be easily prepared by a salt-forming reaction using a conventional method. It is something. For example, basic amino acids (0.1 mol)
Dissolve in 300 ml of distilled water at room temperature with stirring,
Then, a basic amino acid salt can be prepared by dissolving an acidic amino acid or an N-lower aliphatic acyl sulfur-containing amino acid (0.1 mol) at room temperature to 40°C with stirring. The acidic or basic amino acids and N-lower aliphatic acyl sulfur-containing amino acids used as raw materials for the salt-forming reaction may be optically active or optically inactive racemic forms; Even in this case, a basic amino acid salt having a remarkable conditioning effect can be obtained by carrying out the above reaction. In the present invention, the amount of the basic amino acid salt added to the shampoo composition is usually about 0.5 to 10
%W/V is appropriate, but especially in the case of basic amino acid salts of acidic amino acids, it is approximately 1.5 to 3%W/V.
Approximately W/V% is preferable, and furthermore, when blending a mixture of a basic amino acid salt of an acidic amino acid and a basic amino acid salt of an N-lower aliphatic acyl sulfur-containing amino acid, the mixing ratio thereof is approximately 5%. :1 to 2:1 is suitable. In this case especially 1-2
It is preferable to mix it in an amount of about W/V%. According to the present invention, the shampoo composition includes polyoxyethylene higher alkyl ether sulfate salts such as sodium polyoxyethylene lauryl ether sulfate, sodium polyoxyethylene myristyl ether sulfate, triethanolamine lauryl sulfate salt, ammonium lauryl sulfate salt, Higher alkanol sulfate salts such as sodium lauryl sulfate, 2-lauryl-
Add a surfactant such as N-carboxymethyl-N-hydroxyethylimidazolinium betaine or higher alcohol sulfate salt to purified water at a rate of about 15 to
It is prepared by adding a basic amino acid salt at the above ratio and dissolving it. The shampoo composition prepared above includes foaming agents such as fatty acid alkanolamides such as coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, and myristic acid diethanolamide, and tertiary amine oxides such as lauryl dimethylamine oxide. Ordinary shampoo composition additives such as foam stabilizers, thickeners, humectants, bactericidal agents, preservatives, colorants, fragrances, etc. can be blended, and even if such additives are blended, The conditioning effect of the shampoo composition of the present invention is not impaired in any way. Experimental Example 1 (1) Preparation of shampoo composition (shampoo composition of the present invention) Among the formulations shown in Table 1 below, sodium polyoxyethylene lauryl ether sulfate and lauryl dimethylamine oxide were added to half of the purified water. The mixture is dissolved under stirring, and a basic amino acid salt is mixed and dissolved therein. A shampoo composition is prepared by adding the remaining amount of purified water to this solution to make a total volume of 100 ml. (Control Shampoo Composition) A shampoo composition is prepared by using isopropyl myristate in place of the basic amino acid salt and performing the same treatment as above. (2) Experimental method (half-head method) and results Four subjects were employed as subjects, and the left and right vertical halves of their hair were used for each. Two of the subjects used the right half of their hair, and the other two used the left half of their hair, and the hair was washed with the shampoo composition of the present invention in a conventional manner. The remaining hair on the head was treated in the same manner with a control shampoo composition, and the two were compared. After washing, the hair was thoroughly washed with water and dried. The hair was evaluated by scoring by 20 hair stylists, and the final evaluation was made using the maximum number of evaluation values. The results are shown in Table 2.

【table】

【table】

[Table] ◎: Significantly superior to the control.
○: Clearly superior to the control.
Experimental Example 2 (1) Preparation of shampoo composition (shampoo composition of the present invention) Among the formulations shown in Table 3 below, sodium polyoxyethylene lauryl ether sulfate and lauryl dimethylamine oxide were added to half of the purified water. The mixture is dissolved under stirring, and a basic amino acid salt is mixed and dissolved therein. A shampoo composition is prepared by adding the remaining amount of purified water to this solution to make a total volume of 100 ml. (Control Shampoo Composition) A shampoo composition is prepared by using isopropyl myristate in place of the basic amino acid salt and performing the same treatment as above. (2) Experimental method and results The experimental method was the same as in Experimental Example 1.
The results are shown in Table 4.

【table】

[Table] Example 1 <Formulation> Aspartic acid-arginine equimolar salt 2 g Lauryl sulfate triethanolamine salt 15 g Lauryl dimethylamine oxide 3 g Icpropyl myristate 0.5 g Oleyl alcohol 0.5 g Colorant Appropriate amount Flavor Appropriate amount Above Dissolve each ingredient in the formula in purified water and make a total of 100%
Shampoo as ml. Example 2 <Formulation> Equimolar amount of aspartic acid-arginine 2 g Sodium polyoxyethylene lauryl ether sulfate 15 g Coconut oil fatty acid diethanolamide 3 g Isopropyl myristate 0.5 g Oleyl alcohol 0.5 g Colorant Appropriate amount Fragrance Appropriate amount Above formulation Dissolve each component in purified water and make a total amount of 100%
Shampoo as ml. Example 3 <Formulation> Glutamic acid-arginine equimolar salt 2.5g 2-lauryl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine
15 g Lauryl dimethylamine oxide 3 g Myristate isopropyl ester 0.5 g Oleyl alcohol 0.5 g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above recipe in purified water to make a total amount of 100 g
Shampoo as ml. Example 4 <Formulation> Glutamic acid-arginine equimolar salt 2.5g 2-lauryl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine
15 g Coconut oil fatty acid diethanolamide 3 g Myristate isopropyl ester 0.5 g Oleyl alcohol 0.5 g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above formulation in purified water to make a total amount of 100 g
Shampoo as ml. Example 5 <Formulation> Aspartic acid-lysine equimolar salt 2.0 g Sodium polyoxyethylene lauryl ether sulfate 15 g Coconut oil fatty acid diethanolamide 3 g Myristate isopropyl ester 0.5 g Oleyl alcohol 0.5 g Coloring agent Appropriate amount Flavor Appropriate amount Above formulation Dissolve each component in purified water, total amount 100
Shampoo as ml. Example 6 <Formulation> N-acetylmethionine-arginine equimolar salt
1.0g Sodium polyoxyethylene lauryl ether sulfate 15g Lauryl dimethylamine oxide 3g Myristate isopropyl ester 0.5g Oleyl alcohol 0.5g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above recipe in purified water, total amount 100g
Shampoo as ml. Example 7 <Formulation> N-acetylcysteine-arginine equimolar salt
1.0g Sodium polyoxyethylene lauryl ether sulfate 15g Lauryl dimethylamine oxide 3g Isopropyl myristate 0.5g Oleyl alcohol 0.5g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above recipe in purified water, total amount 100g
Shampoo as ml. Example 8 <Formulation> Aspartic acid-arginine equimolar salt 1.5g N-acetylcysteine-arginine equimolar salt
1.0g Lauryl sulfate triethanolamine salt 15g Lauryl dimethylamine oxide 3g Myristate isopropyl ester 0.5g Oleyl alcohol 0.5g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above recipe in purified water, total amount 100g
Shampoo as ml. Example 9 <Formulation> Aspartic acid-arginine equimolar salt 4 g 2-lauryl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine
10 g Sodium polyoxyethylene lauryl ether sulfate 10 g Coconut oil fatty acid diethanolamide 3 g Isopropyl myristate 0.5 g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above recipe in purified water to make a total volume of 100 g
Shampoo as ml. Example 10 <Formulation> Glutamic acid-lysine equimolar salt 7 g Lauryl sulfate triethanolamine salt 20 g Coconut oil fatty acid diethanolamide 3 g Myristate isopropyl ester 0.5 g Oleyl alcohol 0.5 g Colorant Appropriate amount Flavor Appropriate amount Each component of the above formulation Dissolve in purified water and make a total amount of 100
Shampoo as ml. Example 11 <Formulation> N-acetylcysteine-arginine equimolar salt
0.5g 2-lauryl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine
5 g Sodium polyoxyethylene lauryl ether sulfate 15 g Coconut oil fatty acid diethanolamide 3 g Isopropyl myristate 0.5 g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above recipe in purified water to make a total amount of 100 g
Shampoo as ml. Example 12 <Formulation> N-acetylmethionine-lysine equimolar salt
5 g Lauryl sulfate triethanolamine salt 15 g Coconut oil fatty acid diethanolamide 3 g Myristate isopropyl ester 0.5 g Oleyl alcohol 0.5 g Colorant Appropriate amount Fragrance Appropriate amount Dissolve each component of the above recipe in purified water to make a total of 100 g
Shampoo as ml. Example 13 <Formulation> Aspartic acid-arginine equimolar salt 3.2g N-acetylmethionine-arginine equimolar salt
0.8 g Sodium polyoxyethylene lauryl ether sulfate 15 g Lauryl dimethylamine oxide 3 g Isopropyl myristate 0.5 g Colorant as appropriate amount Flavor as appropriate amount Dissolve each component of the above recipe in purified water to make a total volume of 100 g
Shampoo as ml. Example 14 <Formulation> Glutamic acid-lysine equimolar salt 1.5g N-acetylcysteine-arginine equimolar salt
0.5 g Ammonium lauryl sulfate 15 g Lauric acid monoethanolamide 3 g Oleyl alcohol 0.5 g Coloring agent Appropriate amount Fragrance Appropriate amount Dissolve each component of the above formulation in purified water to make a total amount of 100 g
Shampoo as ml. Example 15 <Formulation>N・N'-diacetylcystine-arginine equimolar salt 1 g Lauryl sulfate triethanolamine salt 15 g Lauryl dimethylamine oxide 3 g Myristate isopropyl ester 0.5 g Oleyl alcohol 0.5 g Colorant Appropriate amount Fragrance Appropriate amount Dissolve each component of the above formulation in purified water and make 100% of the total amount.
Shampoo as ml.

Claims (1)

[Scope of Claims] 1. A shampoo composition comprising a salt of an acidic amino acid or an N-lower aliphatic acyl sulfur-containing amino acid and a basic amino acid, or a mixture thereof. 2. The composition according to claim 1, wherein the salt of the acidic amino acid or the N-lower aliphatic acyl sulfur-containing amino acid and the basic amino acid is an equimolar salt. 3. A salt of an acidic amino acid or an N-lower aliphatic acyl sulfur-containing amino acid and a basic amino acid, or a mixture thereof, in an amount of about 0.5 to 10 W/W to the composition.
% of the composition according to claim 1 or 2. 4 Basic amino acid salts of acidic amino acids are aspartic acid/arginine equimolar salts, aspartic acid,
The composition according to claim 2 or 3, which is an equimolar salt of lysine, an equimolar salt of glutamic acid/arginine, or an equimolar salt of glutamic acid/lysine. 5 The basic amino acid salt of an N-lower aliphatic acyl sulfur-containing amino acid is an equimolar salt of N-acetylmethionine/arginine, an equimolar salt of N-acetylcysteine/arginine, or an equimolar salt of N/N'-diacetylcystine/arginine. A composition according to certain claims 2 or 3. 6. Claims 1, 2, or 2, wherein the mixing ratio of the basic amino acid salt of an acidic amino acid and the basic amino acid salt of an N-lower aliphatic acyl sulfur-containing amino acid is about 5:1 to 2:1. Composition according to item 3.