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JPS5672695A - Preparation of l-leucine - Google Patents

Preparation of l-leucine

Info

Publication number
JPS5672695A
JPS5672695A JP14819479A JP14819479A JPS5672695A JP S5672695 A JPS5672695 A JP S5672695A JP 14819479 A JP14819479 A JP 14819479A JP 14819479 A JP14819479 A JP 14819479A JP S5672695 A JPS5672695 A JP S5672695A
Authority
JP
Japan
Prior art keywords
leucine
medium
resistant strain
liquid medium
escherichia coli
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14819479A
Other languages
Japanese (ja)
Other versions
JPS6234397B2 (en
Inventor
Takayasu Tsuchida
Shigeru Nakamori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP14819479A priority Critical patent/JPS5672695A/en
Publication of JPS5672695A publication Critical patent/JPS5672695A/en
Publication of JPS6234397B2 publication Critical patent/JPS6234397B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare a large amount of L-leucine, by the aerobic cultivation of a β-2-thienylanlanine-resistant strain belonging to Escherichia genus in a liquid medium.
CONSTITUTION: A β-2-thienylalanine-resistant strain such as Echerichia coli AJ11478, Escherichia coli AJ11479, etc. derived from Escherichia coli K-12 by induced mutation, is cultured in a conventional medium, and the accumulated L- leucine is separated by conventional process. The medium is e.g. a liquid medium containing glucose, ammonium sulfate, a phosphate, etc., and the culturing is carried out under aerobic conditions.
COPYRIGHT: (C)1981,JPO&Japio
JP14819479A 1979-11-15 1979-11-15 Preparation of l-leucine Granted JPS5672695A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14819479A JPS5672695A (en) 1979-11-15 1979-11-15 Preparation of l-leucine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14819479A JPS5672695A (en) 1979-11-15 1979-11-15 Preparation of l-leucine

Publications (2)

Publication Number Publication Date
JPS5672695A true JPS5672695A (en) 1981-06-16
JPS6234397B2 JPS6234397B2 (en) 1987-07-27

Family

ID=15447351

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14819479A Granted JPS5672695A (en) 1979-11-15 1979-11-15 Preparation of l-leucine

Country Status (1)

Country Link
JP (1) JPS5672695A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0698668A1 (en) 1994-06-30 1996-02-28 Kyowa Hakko Kogyo Co., Ltd. Process for producing L-leucine
US5629180A (en) * 1994-06-30 1997-05-13 Kyowa Hakko Kogyo Co., Ltd. Process for producing L-amino acid

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JP2009118740A (en) 2006-03-03 2009-06-04 Ajinomoto Co Inc Method for producing l-amino acid
EP2055771A3 (en) 2006-03-23 2009-07-08 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
JP2009165355A (en) 2006-04-28 2009-07-30 Ajinomoto Co Inc L-amino acid-producing microorganism and method for producing l-amino acid
WO2007136133A1 (en) 2006-05-23 2007-11-29 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family
RU2006143864A (en) 2006-12-12 2008-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF GENES cynT, cynS, cynX, OR cynR, OR THEIR COMBINATION IS DECREASED
JP2010110217A (en) 2007-02-22 2010-05-20 Ajinomoto Co Inc L-amino acid-producing microorganism and method for producing l-amino acid
EP2192170B1 (en) 2007-09-04 2017-02-15 Ajinomoto Co., Inc. Amino acid-producing microorganism and method of producing amino acid
RU2396336C2 (en) 2007-09-27 2010-08-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) METHOD OF PRODUCING AMINO ACIDS USING Escherichia GENUS BACTERIA
WO2009093703A1 (en) 2008-01-23 2009-07-30 Ajinomoto Co., Inc. Method of producing l-amino acid
RU2008105793A (en) 2008-02-19 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR DESIGNING OPERONS CONTAINING TRANSLATION-CONJUGATED GENES, BACTERIA CONTAINING SUCH OPERON, METHOD FOR PRODUCING USEFUL METABOLITIS AND METHOD FOR EXPRESS MONITORING
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
RU2460793C2 (en) 2010-01-15 2012-09-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Method for producing l-amino acids with use of bacteria of enterobacteriaceae family
JP2013074795A (en) 2010-02-08 2013-04-25 Ajinomoto Co Inc MUTANT rpsA GENE AND METHOD FOR PRODUCING L-AMINO ACID
RU2471868C2 (en) 2010-02-18 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Mutant adenylate cyclase, dna coding it, bacteria of enterobacteriaceae family containing said dan and method for preparing l-amino acids
RU2501858C2 (en) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR OBTAINING L-AMINOACID USING BACTERIUM OF Enterobacteriaceae FAMILY
RU2482188C2 (en) 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR PREPARING L-ARGININE WITH USE OF BACTERIA OF GENUS Escherichia WHEREIN astCADBE OPERON IS INACTIVATED
JP2014036576A (en) 2010-12-10 2014-02-27 Ajinomoto Co Inc Method for producing l-amino acids
RU2011134436A (en) 2011-08-18 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACID USING THE ENTEROBACTERIACEAE FAMILY POSSESSING AN INCREASED EXPRESSION OF GENES OF THE CASCADE OF THE FORMATION OF FLAGELLS AND CELL MOBILITY
RU2012112651A (en) 2012-04-02 2013-10-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") SELF-INDUCED EXPRESSION SYSTEM AND ITS APPLICATION FOR PRODUCING USEFUL METABOLITES USING THE Enterobacteriaceae Family Bacteria
RU2013118637A (en) 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE yjjK GENE IS ADJUSTABLE
JP2016165225A (en) 2013-07-09 2016-09-15 味の素株式会社 Method for producing useful substance
RU2013140115A (en) 2013-08-30 2015-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae FAMILY IN WHICH THE EXPRESSION OF THE znuACB GENERAL CLUSTER IS DISORDERED
JP2016192903A (en) 2013-09-17 2016-11-17 味の素株式会社 Method for manufacturing l-amino acid from biomass derived from seaweed
RU2013144250A (en) 2013-10-02 2015-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae FAMILY IN WHICH THE EXPRESSION OF A GENE CODING A PHOSPHATE TRANSPORTER IS DECREASED
JP6459962B2 (en) 2013-10-21 2019-01-30 味の素株式会社 Method for producing L-amino acid
RU2014105547A (en) 2014-02-14 2015-08-20 Адзиномото Ко., Инк. METHOD FOR PRODUCING L-AMINO ACIDS USING THE ENTEROBACTERIACEAE FAMILY HAVING A SUPER EXPRESSED GENE yajL
RU2015120052A (en) 2015-05-28 2016-12-20 Аджиномото Ко., Инк. A method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family in which gshA gene expression is weakened
CN109121422B (en) 2016-02-25 2021-12-21 味之素株式会社 Method for producing L-amino acids using bacteria of the Enterobacteriaceae family overexpressing genes coding for iron exporters
JP7066977B2 (en) 2017-04-03 2022-05-16 味の素株式会社 Manufacturing method of L-amino acid
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
BR112021014194A2 (en) 2019-02-22 2021-12-28 Ajinomoto Kk Method for producing an l-amino acid
JP2020162549A (en) 2019-03-29 2020-10-08 味の素株式会社 Control device, control method and program, and method for producing organic compound
BR112021017870A2 (en) 2019-04-05 2021-12-07 Ajinomoto Kk Method for producing an l-amino acid
WO2021060438A1 (en) 2019-09-25 2021-04-01 Ajinomoto Co., Inc. Method for producing l-amino acids by bacterial fermentation
JPWO2023195475A1 (en) 2022-04-04 2023-10-12

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0698668A1 (en) 1994-06-30 1996-02-28 Kyowa Hakko Kogyo Co., Ltd. Process for producing L-leucine
US5629180A (en) * 1994-06-30 1997-05-13 Kyowa Hakko Kogyo Co., Ltd. Process for producing L-amino acid
US5744331A (en) * 1994-06-30 1998-04-28 Kyowa Hakko Kogyo Co., Ltd. Process for producing L-leucine

Also Published As

Publication number Publication date
JPS6234397B2 (en) 1987-07-27

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