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JPS5470265A - Substituted indolinone and its preparation - Google Patents

Substituted indolinone and its preparation

Info

Publication number
JPS5470265A
JPS5470265A JP13495277A JP13495277A JPS5470265A JP S5470265 A JPS5470265 A JP S5470265A JP 13495277 A JP13495277 A JP 13495277A JP 13495277 A JP13495277 A JP 13495277A JP S5470265 A JPS5470265 A JP S5470265A
Authority
JP
Japan
Prior art keywords
compound
formula
indolinone
amino
dichlorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13495277A
Other languages
Japanese (ja)
Inventor
Isao Hashiba
Yumiko Ando
Ikuo Kawakami
Ryozo Sakota
Kazuo Nagano
Toshiki Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Priority to JP13495277A priority Critical patent/JPS5470265A/en
Publication of JPS5470265A publication Critical patent/JPS5470265A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

NEW MATERIAL:1-(4-amino-2,6-dichlorophenyl) indolinone of formula I.
USE: An intermediate for 2-(2,6-dichloroanilino) phenylacetic acid useful as a raw material for medicines having pharmacological action, e.g. anti-inflammatory, analgesic, and antipyretic actions.
PROCESS: The amino group of 2,6-dichloro-4-nitroaniline is diazotized to give a diazonium salt, which is substituted by halogen, e.g. I, Br, Cl, etc. to form 2,6- dichloro-4-nitrohalobenzene (A). The compound (A) is reacted with aniline to form the compound of formula II, which is reacted with oxalyl chloride to form the compound of formula III. The compound of formula III is converted to the compound of formula IV by the Friedel-Crafts reaction. The compound of the formula IV is reduced to give 1-(4-amino-2,6-dichlorophenyl) indolinone via the compound of formula V.
COPYRIGHT: (C)1979,JPO&Japio
JP13495277A 1977-11-10 1977-11-10 Substituted indolinone and its preparation Pending JPS5470265A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13495277A JPS5470265A (en) 1977-11-10 1977-11-10 Substituted indolinone and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13495277A JPS5470265A (en) 1977-11-10 1977-11-10 Substituted indolinone and its preparation

Publications (1)

Publication Number Publication Date
JPS5470265A true JPS5470265A (en) 1979-06-05

Family

ID=15140395

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13495277A Pending JPS5470265A (en) 1977-11-10 1977-11-10 Substituted indolinone and its preparation

Country Status (1)

Country Link
JP (1) JPS5470265A (en)

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