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JPH10500978A - p53タンパク質の調節による腫瘍の治療方法 - Google Patents

p53タンパク質の調節による腫瘍の治療方法

Info

Publication number
JPH10500978A
JPH10500978A JP8500420A JP50042096A JPH10500978A JP H10500978 A JPH10500978 A JP H10500978A JP 8500420 A JP8500420 A JP 8500420A JP 50042096 A JP50042096 A JP 50042096A JP H10500978 A JPH10500978 A JP H10500978A
Authority
JP
Japan
Prior art keywords
protein
nucleic acid
calpain
vector
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8500420A
Other languages
English (en)
Japanese (ja)
Inventor
ジヤン−マリー ブランシヤール,
セルジユ カリヨ,
マルク ピエシヤクジク,
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH10500978A publication Critical patent/JPH10500978A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP8500420A 1994-05-31 1995-05-22 p53タンパク質の調節による腫瘍の治療方法 Pending JPH10500978A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR94/06583 1994-05-31
FR9406583A FR2720277B1 (fr) 1994-05-31 1994-05-31 Méthode de traitement des cancers par régulation de la protéine P53.
PCT/FR1995/000670 WO1995033060A1 (fr) 1994-05-31 1995-05-22 Methode de traitement des cancers par regulation de la proteine p53

Publications (1)

Publication Number Publication Date
JPH10500978A true JPH10500978A (ja) 1998-01-27

Family

ID=9463670

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8500420A Pending JPH10500978A (ja) 1994-05-31 1995-05-22 p53タンパク質の調節による腫瘍の治療方法

Country Status (8)

Country Link
EP (1) EP0763121A1 (fi)
JP (1) JPH10500978A (fi)
AU (1) AU714209B2 (fi)
CA (1) CA2190293C (fi)
FI (1) FI120501B (fi)
FR (1) FR2720277B1 (fi)
NO (1) NO321411B1 (fi)
WO (1) WO1995033060A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19518488C1 (de) * 1995-05-19 1996-10-10 Progen Biotechnik Gmbh Autoantigen, geeignet zur Feststellung einer Thromboseneigung
EP0799892A3 (en) * 1996-04-05 1998-08-12 Takeda Chemical Industries, Ltd. Calpain, its production and use
US6232454B1 (en) 1998-02-27 2001-05-15 Incyte Genomics, Inc. Human proteinase molecules
AU2344100A (en) * 1998-11-18 2000-06-05 Canji, Inc. Viral vectors with late transgene expression
AU2001247922A1 (en) * 2000-03-31 2001-10-15 Parker Hughes Institute Calpain inhibitors in cancer treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753665B2 (ja) * 1984-04-20 1995-06-07 財団法人癌研究会 抗転移剤
US5340922B1 (en) * 1988-05-31 1999-11-02 Mclean Hospital Corp Neural calcium-activated neutral proteinase inhibitors
EP0395309B1 (en) * 1989-04-28 1995-12-27 Takara Shuzo Co. Ltd. Human calpastatin-like polypeptide
JPH0641067A (ja) * 1992-04-20 1994-02-15 Kitasato Inst:The 新規カルパイン阻害物質kp−1241及びその製造法
EP0580161A1 (en) * 1992-07-22 1994-01-26 THE McLEAN HOSPITAL CORPORATION Prophylactic and therapeutic treatment of Alzheimer's disease
US5607831A (en) * 1993-03-25 1997-03-04 The United States Of America As Represented By The Department Of Health And Human Services In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death

Also Published As

Publication number Publication date
FI120501B (fi) 2009-11-13
FI964783A0 (fi) 1996-11-29
FR2720277A1 (fr) 1995-12-01
EP0763121A1 (fr) 1997-03-19
CA2190293C (fr) 2011-06-28
AU714209B2 (en) 1999-12-23
WO1995033060A1 (fr) 1995-12-07
CA2190293A1 (fr) 1995-12-07
NO321411B1 (no) 2006-05-08
FI964783L (fi) 1996-11-29
FR2720277B1 (fr) 1996-07-12
NO964772L (no) 1996-11-11
NO964772D0 (no) 1996-11-11
AU2620695A (en) 1995-12-21

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