JPH01199983A - 新規珪素含有ペプチド類、それらの製法および用途 - Google Patents
新規珪素含有ペプチド類、それらの製法および用途Info
- Publication number
- JPH01199983A JPH01199983A JP63316097A JP31609788A JPH01199983A JP H01199983 A JPH01199983 A JP H01199983A JP 63316097 A JP63316097 A JP 63316097A JP 31609788 A JP31609788 A JP 31609788A JP H01199983 A JPH01199983 A JP H01199983A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- trimethylsilylmethyl
- cyclohexylmethyl
- triaza
- butyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3742474.2 | 1987-12-15 | ||
DE3742474 | 1987-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH01199983A true JPH01199983A (ja) | 1989-08-11 |
Family
ID=6342652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63316097A Pending JPH01199983A (ja) | 1987-12-15 | 1988-12-14 | 新規珪素含有ペプチド類、それらの製法および用途 |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPH01199983A (it) |
CH (1) | CH677877A5 (it) |
FR (1) | FR2624513A1 (it) |
GB (1) | GB2212158A (it) |
IT (1) | IT1235166B (it) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06340677A (ja) * | 1990-09-17 | 1994-12-13 | Union Carbide Chem & Plast Co Inc | 潜在性カルバメートシリコンカツプリング剤、及びその製造法及び使用 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100220876B1 (ko) * | 1991-01-02 | 1999-10-01 | 슈테펜엘.네스비트 | 항 바이러스 화합물 |
DE69122266T2 (de) * | 1991-01-02 | 1997-03-27 | Merrell Pharmaceuticals Inc. (N.D.Ges.D. Staates Delaware), Cincinnati, Ohio | Antivirale verbindungen |
WO1995001958A1 (en) * | 1993-07-08 | 1995-01-19 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
AU683927B2 (en) * | 1993-09-09 | 1997-11-27 | Merrell Pharmaceuticals Inc. | Difluoro statone antiviral analogs |
US6114380A (en) * | 1995-12-18 | 2000-09-05 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
EP2261662B1 (en) | 2009-06-10 | 2014-01-22 | Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften | Novel synthetic blocking reagents |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984003044A1 (en) * | 1983-02-07 | 1984-08-16 | Ferring Ab | Enzyme inhibitors |
-
1988
- 1988-12-12 GB GB8828982A patent/GB2212158A/en not_active Withdrawn
- 1988-12-12 FR FR8816432A patent/FR2624513A1/fr not_active Withdrawn
- 1988-12-13 CH CH4597/88A patent/CH677877A5/de not_active IP Right Cessation
- 1988-12-13 IT IT8848638A patent/IT1235166B/it active
- 1988-12-14 JP JP63316097A patent/JPH01199983A/ja active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06340677A (ja) * | 1990-09-17 | 1994-12-13 | Union Carbide Chem & Plast Co Inc | 潜在性カルバメートシリコンカツプリング剤、及びその製造法及び使用 |
Also Published As
Publication number | Publication date |
---|---|
GB2212158A (en) | 1989-07-19 |
IT8848638A0 (it) | 1988-12-13 |
CH677877A5 (it) | 1991-07-15 |
IT1235166B (it) | 1992-06-22 |
FR2624513A1 (fr) | 1989-06-16 |
GB8828982D0 (en) | 1989-01-25 |
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