JP2001526210A - 親油性糖質副腎皮質ステロイドおよび界面活性剤を１つだけ含有するミセルを含んでなる医薬組成物 - Google Patents
親油性糖質副腎皮質ステロイドおよび界面活性剤を１つだけ含有するミセルを含んでなる医薬組成物Info
- Publication number
- JP2001526210A JP2001526210A JP2000525082A JP2000525082A JP2001526210A JP 2001526210 A JP2001526210 A JP 2001526210A JP 2000525082 A JP2000525082 A JP 2000525082A JP 2000525082 A JP2000525082 A JP 2000525082A JP 2001526210 A JP2001526210 A JP 2001526210A
- Authority
- JP
- Japan
- Prior art keywords
- surfactant
- composition
- corticosteroid
- aqueous medium
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
- 229960005294 triamcinolone Drugs 0.000 description 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical class [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704833-4 | 1997-12-22 | ||
| SE9704833A SE9704833D0 (sv) | 1997-12-22 | 1997-12-22 | New formulation |
| PCT/SE1998/002426 WO1999032089A1 (en) | 1997-12-22 | 1998-12-22 | Pharmaceutical compositions comprising micelles comprising lipophilic glucocorticosteroid and only one surfactant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2001526210A true JP2001526210A (ja) | 2001-12-18 |
Family
ID=20409536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000525082A Pending JP2001526210A (ja) | 1997-12-22 | 1998-12-22 | 親油性糖質副腎皮質ステロイドおよび界面活性剤を１つだけ含有するミセルを含んでなる医薬組成物 |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1043973A1 (xx) |
| JP (1) | JP2001526210A (xx) |
| KR (1) | KR20010024789A (xx) |
| CN (1) | CN1283106A (xx) |
| AR (1) | AR017220A1 (xx) |
| AU (1) | AU1993599A (xx) |
| BR (1) | BR9813811A (xx) |
| CA (1) | CA2315782A1 (xx) |
| EE (1) | EE200000388A (xx) |
| HU (1) | HUP0102365A3 (xx) |
| ID (1) | ID26945A (xx) |
| IL (1) | IL136880A0 (xx) |
| NO (1) | NO20003220L (xx) |
| NZ (1) | NZ505073A (xx) |
| PL (1) | PL341361A1 (xx) |
| SE (1) | SE9704833D0 (xx) |
| SK (1) | SK9532000A3 (xx) |
| TR (1) | TR200001977T2 (xx) |
| WO (1) | WO1999032089A1 (xx) |
| ZA (1) | ZA9811461B (xx) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2005018607A1 (ja) * | 2003-08-20 | 2007-11-01 | 味の素株式会社 | 溶解性を改善した医薬品製剤 |
| JP2011503073A (ja) * | 2007-11-13 | 2011-01-27 | メリテイジ ファーマ，インク． | コルチコステロイド組成物 |
| JP2013147480A (ja) * | 2012-01-23 | 2013-08-01 | Cac:Kk | 医薬組成物及びこれを用いた薬用化粧品 |
| US8865692B2 (en) | 2007-11-13 | 2014-10-21 | Meritage Pharma, Inc | Compositions for the treatment of gastrointestinal inflammation |
| US11413296B2 (en) | 2005-11-12 | 2022-08-16 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9902674D0 (sv) * | 1999-07-12 | 1999-07-12 | Astra Ab | New composition |
| SE0000332D0 (sv) * | 2000-01-31 | 2000-01-31 | Astrazeneca Ab | New use |
| US6750210B2 (en) | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
| US6787532B2 (en) * | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
| US6858596B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
| US6777400B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| JP2004505990A (ja) | 2000-08-05 | 2004-02-26 | グラクソ グループ リミテッド | 抗炎症剤としての１７β−カルボチオエート−１７α−アリールカルボニルオキシルオキシアンドロスタン誘導体 |
| GB0019172D0 (en) | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
| US6777399B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| US6858593B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| US6759398B2 (en) | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
| SE0100901D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | New composition |
| UA77656C2 (en) | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
| ES2314052T3 (es) | 2001-04-30 | 2009-03-16 | Glaxo Group Limited | Derivados de ester de 17beta-carbotioato de androstano con un grupo ester ciclico en la posicion 17alfa. |
| GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
| CN100579510C (zh) * | 2006-04-13 | 2010-01-13 | 新疆维吾尔自治区包虫病临床研究所 | 新型前体胶束制剂及其生产方法 |
| KR20110056516A (ko) * | 2008-09-12 | 2011-05-30 | 크리티컬 파머수티컬스 리미티드 | 점막 또는 피부를 통한 치료제의 흡수 개선 |
| CN101982168B (zh) * | 2010-11-02 | 2012-05-23 | 山东大学 | 一种槲皮素纳米胶束制剂及其制备方法 |
| CN102793678B (zh) * | 2011-05-26 | 2017-06-30 | 邓世明 | 一种不含吐温的多烯紫杉醇注射剂的制备方法 |
| DE102011108948A1 (de) * | 2011-07-29 | 2013-01-31 | Achim Göpferich | Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen |
| AU2014291615B2 (en) * | 2013-07-17 | 2019-09-26 | Council Of Scientific & Industrial Research | Pharmaceutical composition for the treatment of diminution of bone tissue |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| KR102086316B1 (ko) * | 2019-09-09 | 2020-03-09 | 한국콜마주식회사 | 경피흡수성이 우수한 화장료 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0179583A1 (en) * | 1984-10-04 | 1986-04-30 | Merck & Co. Inc. | A system for enhancing the water dissolution rate and solubility of poorly soluble drugs |
| US4994439A (en) * | 1989-01-19 | 1991-02-19 | California Biotechnology Inc. | Transmembrane formulations for drug administration |
| SA95160463B1 (ar) * | 1994-12-22 | 2005-10-04 | استرا أكتيبولاج | مساحيق للاستنشاق |
-
1997
- 1997-12-22 SE SE9704833A patent/SE9704833D0/xx unknown
-
1998
- 1998-12-14 ZA ZA9811461A patent/ZA9811461B/xx unknown
- 1998-12-17 AR ARP980106453A patent/AR017220A1/es not_active Application Discontinuation
- 1998-12-22 CA CA002315782A patent/CA2315782A1/en not_active Abandoned
- 1998-12-22 JP JP2000525082A patent/JP2001526210A/ja active Pending
- 1998-12-22 PL PL98341361A patent/PL341361A1/xx unknown
- 1998-12-22 IL IL13688098A patent/IL136880A0/xx unknown
- 1998-12-22 WO PCT/SE1998/002426 patent/WO1999032089A1/en not_active Application Discontinuation
- 1998-12-22 EP EP98964662A patent/EP1043973A1/en not_active Withdrawn
- 1998-12-22 BR BR9813811-1A patent/BR9813811A/pt not_active IP Right Cessation
- 1998-12-22 KR KR1020007006879A patent/KR20010024789A/ko not_active Withdrawn
- 1998-12-22 NZ NZ505073A patent/NZ505073A/xx unknown
- 1998-12-22 AU AU19935/99A patent/AU1993599A/en not_active Abandoned
- 1998-12-22 ID IDW20001131A patent/ID26945A/id unknown
- 1998-12-22 SK SK953-2000A patent/SK9532000A3/sk unknown
- 1998-12-22 TR TR2000/01977T patent/TR200001977T2/xx unknown
- 1998-12-22 CN CN98812507A patent/CN1283106A/zh active Pending
- 1998-12-22 EE EEP200000388A patent/EE200000388A/xx unknown
- 1998-12-22 HU HU0102365A patent/HUP0102365A3/hu unknown
-
2000
- 2000-06-21 NO NO20003220A patent/NO20003220L/no not_active Application Discontinuation
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2005018607A1 (ja) * | 2003-08-20 | 2007-11-01 | 味の素株式会社 | 溶解性を改善した医薬品製剤 |
| US11413296B2 (en) | 2005-11-12 | 2022-08-16 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| JP2011503073A (ja) * | 2007-11-13 | 2011-01-27 | メリテイジ ファーマ，インク． | コルチコステロイド組成物 |
| JP2014055171A (ja) * | 2007-11-13 | 2014-03-27 | Meritage Pharma Inc | コルチコステロイド組成物 |
| US8865692B2 (en) | 2007-11-13 | 2014-10-21 | Meritage Pharma, Inc | Compositions for the treatment of gastrointestinal inflammation |
| US9050368B2 (en) | 2007-11-13 | 2015-06-09 | Meritage Pharma, Inc. | Corticosteroid compositions |
| US10293052B2 (en) | 2007-11-13 | 2019-05-21 | Meritage Pharma, Inc. | Compositions for the treatment of gastrointestinal inflammation |
| US11357859B2 (en) | 2007-11-13 | 2022-06-14 | Viropharma Biologics Llc | Compositions for the treatment of gastrointestinal inflammation |
| JP2013147480A (ja) * | 2012-01-23 | 2013-08-01 | Cac:Kk | 医薬組成物及びこれを用いた薬用化粧品 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010024789A (ko) | 2001-03-26 |
| ZA9811461B (en) | 1999-06-22 |
| PL341361A1 (en) | 2001-04-09 |
| AR017220A1 (es) | 2001-08-22 |
| EP1043973A1 (en) | 2000-10-18 |
| ID26945A (id) | 2001-02-22 |
| CN1283106A (zh) | 2001-02-07 |
| NZ505073A (en) | 2002-09-27 |
| AU1993599A (en) | 1999-07-12 |
| WO1999032089A1 (en) | 1999-07-01 |
| TR200001977T2 (tr) | 2000-12-21 |
| HUP0102365A2 (hu) | 2001-11-28 |
| SE9704833D0 (sv) | 1997-12-22 |
| EE200000388A (et) | 2002-02-15 |
| IL136880A0 (en) | 2001-06-14 |
| SK9532000A3 (en) | 2000-11-07 |
| BR9813811A (pt) | 2000-10-03 |
| NO20003220L (no) | 2000-08-22 |
| CA2315782A1 (en) | 1999-07-01 |
| NO20003220D0 (no) | 2000-06-21 |
| HUP0102365A3 (en) | 2002-01-28 |
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