JP2000290133A - Bleaching preparation - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject bleaching preparation controlling melanization by ultraviolet damage, promoting discharge of melanin pigment, especially exhibiting excellent bleaching effect by including yeast essence or a fungus culture product and an extract of wheat embryo bud. SOLUTION: This bleaching preparation contains (A) a yeast essence or a fungus cultured substance containing the essence and (B) an extract of wheat embryo bud. Preferably the cosmetic contains 0.001-20 wt.% calculated as a solid content of the component A and 0.0001-10 wt.% of the component B. For example, a cultured product of lactic bacteria (e.g. Streptococcus thermophilus, Lactobacillus bulugarius, Streptococcus lactis, etc.), cultured in a medium containing a yeast essence, a cultured product of a mushroom microbial cell [e.g. Lentinus edodes, Pleurotus ostreatus, etc.], etc., may be cited as the component A. A substance obtained by extracting wheat embryo bud with water, concentrating and filtering can be used as the composition B.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to cosmetics and quasi-drugs.

[0002]

2. Description of the Related Art Conventionally, whitening cosmetics for the purpose of preventing or treating skin spots and freckles include L-ascorbic acid and its derivatives, hydroquinone derivatives, pyrones of kojic acid, placenta extract and the like. A placenta extract is included.

[0003] These substances have effects such as suppression of melanin production and light-color bleaching action of the produced melanin, and are widely known as substances having a whitening effect. However, when these substances are used alone, for example, L-ascorbic acid and its derivatives have insufficient storage stability and their effects are not sufficiently exerted, and hydroquinone derivatives have insufficient safety, for example, they have a problem in safety. It was not something.

[0004]

The inventors of the present invention have conducted intensive studies to solve the above-mentioned drawbacks. As a result, the whitening cosmetics described below suppress melanin production due to ultraviolet damage and promote excretion of melanin pigments, The present inventors have found that a whitening effect is synergistically developed, and completed the present invention.

[0005] That is, an object of the present invention is to provide a whitening cosmetic which suppresses melanin production due to ultraviolet damage and promotes excretion of melanin pigment, and expresses a particularly excellent whitening effect.

[0006]

The present invention, which achieves the above object, is a whitening cosmetic comprising a yeast extract or a bacterial culture containing the yeast extract and an extract obtained from wheat germ.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION An embodiment of the present invention is a whitening cosmetic. Hereinafter, the configuration of the present invention will be described in detail.

The yeast extract used in the present invention includes, for example, commercially available yeast extract for reagents and industrial use, and more specifically, yeast extract for reagents (manufactured by Difco) and industrial raw materials. Biodyne (manufactured by Brooks Industry Co., Ltd.) which is a yeast extract, and a chitocatalyzer (manufactured by Bio-Dell Co.) are exemplified.

The bacterial culture containing yeast extract used in the present invention includes, for example, lactic acid bacteria culture cultured on a medium containing yeast extract, mushroom cell culture and the like. As the lactic acid bacteria, for example, Steptococcus thermop
hilus, Lactobacillusbulugarius, Streptococcus lact
is, etc., and as mushroom cells, for example, Lent
Examples include inus edodes (shiitake), Pleurotus ostreatus (hiratake), and Flammuiina velutipes (enokitake).

The amount of these components is preferably 0.001 to 20.0% by weight in terms of solids in the total amount of the whitening cosmetic of the present invention, but is not limited thereto. .

The extract selected from wheat germ used in the present invention can be obtained by, for example, extracting with water, concentrating the extract, and filtering. However, it is not limited to this manufacturing method.

The amount of the extract obtained from the wheat germ of the present invention is preferably 0.0001 to 10.0% by weight in terms of solids in the total amount of the whitening cosmetic of the present invention, but is not limited thereto. .

In the cosmetic of the present invention, in addition to the above-mentioned raw materials,
Dyes, fragrances, preservatives, surfactants, pigments, antioxidants, humectants, ultraviolet absorbers, and the like can be appropriately compounded as long as the object of the present invention is achieved.

The dosage form of the cosmetic of the present invention is a cream.
Any of the dosage forms commonly used in cosmetics, such as emulsions, emulsions, lotions, packs, etc. may be used.

[0015] In the case of a lotion, for example, this cosmetic can be produced by a usual method such as mixing and dissolving each component.

[0016]

The present invention will be described below in detail based on examples and comparative examples. In addition, the compounding% shown in the examples is% by weight. The skin color lightness recovery test method and sensory test (whitening effect) described in the examples are as follows. In addition, methods for preparing a bacterial culture containing yeast extract and an extract obtained from wheat germ used in the examples are as follows, but the scope of the present invention is not limited only to these.

(Method for Preparing Culture of Bacteria Containing Yeast Extract) 10 g of skim milk and 1 g of potato dextrose plus 10 g of yeast extract (manufactured by Difco) are dissolved in purified water, and the volume is increased to 100 ml. The medium was prepared by autoclaving for 20 minutes. This was pre-cultured with a Brain Heart Infusion medium (Difco) at 30 ° C. for 16 hours.
1% of ctis (IFO 12007) was inoculated. After culturing at 30 ° C. for 24 hours, the culture supernatant from which the cells were removed by centrifugation was used for 80 hours.
What was treated at 30 ° C. for 30 minutes was used as a bacterial culture.

(Preparation Method of Extract Obtained from Wheat Germ) 50 g of wheat germ is immersed in 1 L of water, and stirred for 1 hour.
Leave day and night. The obtained liquid was concentrated and then filtered. Thus, 15.7 g of wheat germ extract (solid equivalent: 0.
16 g) were obtained.

(1) Skin Color Brightness Recovery Test Method The back skin of 20 subjects was irradiated with ultraviolet rays in the UV-B region twice as much as the minimum erythema dose, and a sample-applied portion and a non-applied portion were set. The reference lightness (V0 value, V0 'value) was measured. Then, apply the sample twice a day to the application site.
After continuous application for 5 weeks, the lightness (Vn value, Vn) of the skin at the application site and the non-application site after 3, 6, 9, 12, and 15 weeks
n ′ value), and the recovery of skin color was evaluated according to the following criteria. The lightness of the skin (Munsell color system V
Value) was calculated from the X, Y, and Z values obtained by measuring with a high-speed spectral colorimeter. In addition, the evaluation was shown as an average value of the evaluation points after 3 weeks for 20 subjects.

[0020]

[Table 1]

(2) Sensory test Twenty test subjects evaluated the characteristics of the sample after continuously using the sample for 10 days. The evaluation was shown by the number of respondents who answered that "the whitening effect was felt" to the questionnaire item of the whitening effect.

Examples 1-3, Comparative Examples 1-3 Bacterial cultures containing yeast extract and extracts obtained from wheat germ were blended in the compositions shown in Tables 2 and 3, and skin creams were prepared according to the following preparation methods. Prepared. The above test was performed for each, and the results are shown in Table 3.

[0023]

[Table 2]

[0024]

[Table 3]

Preparation method: (A) and (B) are uniformly dissolved at 70 ° C., and (B) is poured into (A) while stirring (A) to emulsify and disperse. Prepare by cooling to ° C.

Characteristics: The skin creams of Examples 1 to 3 of the present invention showed good results in the above tests. On the other hand, the skin creams of Comparative Examples 1 to 3 did not show a sufficient effect and were inferior to the examples of the present invention.

Example 4 (Skin lotion) A skin lotion of the present invention was prepared according to the composition shown in Table 4 by the following method.

[0028]

[Table 4]

Preparation method: Each component was mixed and dissolved to prepare a skin lotion.

Properties: The skin lotion of Example 4 showed good results in the above tests.

Example 5 (Day Essence) According to the composition shown in Table 5, the day essence (daytime beauty liquid) of the present invention was prepared by the following method.

[0032]

[Table 5]

Preparation method: (A) and (B) were mixed and dissolved at 70 ° C. for each component, (B) was added to (A), mixed, stirred and cooled to 30 ° C.

Characteristics: The day essence of Example 4 is as follows:
Good results were shown in the above tests.

[0035]

As described above, it is apparent that the present invention provides an excellent whitening cosmetic which exhibits a whitening effect in a short period of time.

Continued on front page (72) Inventor Toshio Horikoshi 5-28, Kotobuki-cho, Odawara-shi, Kanagawa F-term in Kanebo Co., Ltd. Basic Research Laboratory 4C083 AA082 AA111 AA112 AB242 AC012 AC022 AC092 AC122 AC242 AC392 AC442 AC482 AC662 AD352 AD572 CC04 CC05 DD27 DD31 EE16

Claims (1)

[Claims] 1. A whitening cosmetic comprising a yeast extract or a bacterial culture containing the yeast extract and an extract obtained from wheat germ.