IT8222046A0 - Metodo per la sintesi in fase solida di polipeptidi retroinvertiti - Google Patents
Metodo per la sintesi in fase solida di polipeptidi retroinvertitiInfo
- Publication number
- IT8222046A0 IT8222046A0 IT8222046A IT2204682A IT8222046A0 IT 8222046 A0 IT8222046 A0 IT 8222046A0 IT 8222046 A IT8222046 A IT 8222046A IT 2204682 A IT2204682 A IT 2204682A IT 8222046 A0 IT8222046 A0 IT 8222046A0
- Authority
- IT
- Italy
- Prior art keywords
- polypeptides
- inverted
- solid phase
- phase synthesis
- synthesis
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000010532 solid phase synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22046/82A IT1190891B (it) | 1982-06-24 | 1982-06-24 | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
| AT83200889T ATE30033T1 (de) | 1982-06-24 | 1983-06-17 | Verfahren zur herstellung von retro-inverso polypeptiden in fester phase. |
| DE8383200889T DE3373908D1 (en) | 1982-06-24 | 1983-06-17 | Method for the solid-phase synthesis of retro-inverso polypeptides |
| EP83200889A EP0097994B1 (en) | 1982-06-24 | 1983-06-17 | Method for the solid-phase synthesis of retro-inverso polypeptides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22046/82A IT1190891B (it) | 1982-06-24 | 1982-06-24 | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8222046A0 true IT8222046A0 (it) | 1982-06-24 |
| IT1190891B IT1190891B (it) | 1988-02-24 |
Family
ID=11190672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT22046/82A IT1190891B (it) | 1982-06-24 | 1982-06-24 | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0097994B1 (it) |
| AT (1) | ATE30033T1 (it) |
| DE (1) | DE3373908D1 (it) |
| IT (1) | IT1190891B (it) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984003044A1 (en) * | 1983-02-07 | 1984-08-16 | Ferring Ab | Enzyme inhibitors |
| IT1164225B (it) * | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
| IT1164240B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica |
| IT1164239B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica |
| US4668476A (en) * | 1984-03-23 | 1987-05-26 | Applied Biosystems, Inc. | Automated polypeptide synthesis apparatus |
| IT1178789B (it) * | 1984-12-21 | 1987-09-16 | Assorenti | Peptidi retro-invertiti analoghi del potenziatore della bradichinina bpp 5a |
| IT1178786B (it) * | 1984-12-21 | 1987-09-16 | Assorenti | Analoghi retro-inverso parzialmente modificati della neurotensina |
| IT1184317B (it) * | 1985-02-05 | 1987-10-28 | Eniricerche Spa | Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a |
| IT1190389B (it) * | 1985-09-19 | 1988-02-16 | Eniricerche Spa | Esapeptidi ad attivita' ipotensiva |
| IT1188206B (it) * | 1985-11-28 | 1988-01-07 | Eniricerche Spa | Procedimento per la sintesi in fase solida di peptidi in cui almeno un legame ammidico e' retroinvertito |
| GB2187461A (en) * | 1986-02-03 | 1987-09-09 | Medical Res Council | Monitoring method for the synthesis of a linear of amino acid residues |
| IT1196500B (it) * | 1986-07-16 | 1988-11-16 | Eniricerche Spa | Derivati dell'acido malonico e metodi per la loro sintesi |
| ES2052517T3 (es) * | 1986-07-16 | 1994-07-16 | Eniricerche Spa | Analogos de tuftsina parcialmente retroinversos, metodo de preparacion de los mismos y composiciones farmaceuticas que los contienen. |
| JP4116072B2 (ja) | 1992-08-27 | 2008-07-09 | バイオクローンズ（プロプライエタリー）リミテッド | 逆向き、鏡像体および逆向き鏡像体合成ペプチド類似物 |
| FR2717081B1 (fr) * | 1994-03-14 | 1996-06-21 | Centre Nat Rech Scient | Rétropeptides, anticorps dirigés contre ces derniers, et leurs utilisations pour la vaccination et le diagnostic in vitro. |
| US6916904B2 (en) | 2002-04-24 | 2005-07-12 | Zolaris Biosciences, Llc | Inhibition of immune complex formation |
| CA2559887C (en) | 2004-03-10 | 2018-12-04 | Trinity Therapeutics, Inc. | Method for inhibiting immune complex formation in a subject |
| US8895002B2 (en) | 2007-04-09 | 2014-11-25 | The General Hospital Corporation | Hemojuvelin fusion proteins and uses thereof |
| TWI573806B (zh) | 2008-04-17 | 2017-03-11 | 巴克斯歐塔公司 | 生物活性胜肽 |
| MY160699A (en) | 2008-07-18 | 2017-03-15 | Trinity Therapeutics Inc | Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome |
| EP2688595B1 (en) | 2011-03-25 | 2018-03-14 | Children's Medical Center Corporation | Lin28-mediated control of let-7 biogenesis |
| EP2717898B1 (en) | 2011-06-10 | 2018-12-19 | Bioverativ Therapeutics Inc. | Pro-coagulant compounds and methods of use thereof |
| CA3077804C (en) | 2012-01-09 | 2023-07-25 | Serpin Pharma, Llc | Peptides and methods of using same |
| US9421245B2 (en) | 2012-06-25 | 2016-08-23 | The Brigham And Women's Hospital, Inc. | Targeted therapeutics |
| CN105473154A (zh) | 2013-03-12 | 2016-04-06 | 通用医疗公司 | 修饰的缪勒抑制物质(mis)蛋白及其用于疾病治疗的用途 |
| US10584147B2 (en) | 2013-11-08 | 2020-03-10 | Biovertiv Therapeutics Inc. | Procoagulant fusion compound |
| WO2016044707A1 (en) | 2014-09-18 | 2016-03-24 | Cedars-Sinai Medical Center | Compositions and methods for treating fibrosis |
| EP3285795B1 (en) | 2015-04-22 | 2022-11-16 | Cedars-Sinai Medical Center | Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes and obesity |
| CN113425837A (zh) | 2015-08-28 | 2021-09-24 | 赛品制药有限责任公司 | 用于疾病治疗的方法 |
| WO2017075478A2 (en) | 2015-10-28 | 2017-05-04 | The Broad Institute Inc. | Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures |
| WO2017075465A1 (en) | 2015-10-28 | 2017-05-04 | The Broad Institute Inc. | Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3 |
| WO2017075451A1 (en) | 2015-10-28 | 2017-05-04 | The Broad Institute Inc. | Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1 |
| WO2018049025A2 (en) | 2016-09-07 | 2018-03-15 | The Broad Institute Inc. | Compositions and methods for evaluating and modulating immune responses |
| CN112739367A (zh) | 2018-09-10 | 2021-04-30 | 肺疾治疗公司 | Cav-1蛋白的修饰的肽片段及其在纤维化治疗中的用途 |
| KR20210057127A (ko) | 2018-09-10 | 2021-05-20 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 카베올린-1 펩티드의 건조 분말 제형 및 이의 사용 방법 |
| WO2023200887A1 (en) | 2022-04-13 | 2023-10-19 | Paradigm Immunotherapeutics, Inc. | Methods of preventing or treating infection by respiratory viruses including sars-cov-2 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3862114A (en) * | 1971-11-22 | 1975-01-21 | Ici Australia Ltd | Analogs of substance p |
-
1982
- 1982-06-24 IT IT22046/82A patent/IT1190891B/it active
-
1983
- 1983-06-17 DE DE8383200889T patent/DE3373908D1/de not_active Expired
- 1983-06-17 AT AT83200889T patent/ATE30033T1/de not_active IP Right Cessation
- 1983-06-17 EP EP83200889A patent/EP0097994B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0097994A2 (en) | 1984-01-11 |
| IT1190891B (it) | 1988-02-24 |
| DE3373908D1 (en) | 1987-11-05 |
| EP0097994A3 (en) | 1985-11-27 |
| EP0097994B1 (en) | 1987-09-30 |
| ATE30033T1 (de) | 1987-10-15 |
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