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IT1274356B - Tassani semisintetici odtati di attivita' antitumorale - Google Patents

Tassani semisintetici odtati di attivita' antitumorale

Info

Publication number
IT1274356B
IT1274356B ITMI941592A ITMI941592A IT1274356B IT 1274356 B IT1274356 B IT 1274356B IT MI941592 A ITMI941592 A IT MI941592A IT MI941592 A ITMI941592 A IT MI941592A IT 1274356 B IT1274356 B IT 1274356B
Authority
IT
Italy
Prior art keywords
antitumoural activity
semisynthetic
taxanes
antitumoural
activity
Prior art date
Application number
ITMI941592A
Other languages
English (en)
Inventor
Ezio Bombardelli
Bellis Paolo De
Bruno Gabetta
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of ITMI941592A0 publication Critical patent/ITMI941592A0/it
Priority to ITMI941592A priority Critical patent/IT1274356B/it
Priority to RO97-00125A priority patent/RO115875B1/ro
Priority to JP8505456A priority patent/JP2986550B2/ja
Priority to CA002195844A priority patent/CA2195844C/en
Priority to PCT/EP1995/002896 priority patent/WO1996003394A1/en
Priority to SK100-97A priority patent/SK281526B6/sk
Priority to KR1019970700442A priority patent/KR100220490B1/ko
Priority to DE69507702T priority patent/DE69507702T2/de
Priority to CN95194333A priority patent/CN1073105C/zh
Priority to PL95318289A priority patent/PL187579B1/pl
Priority to AU31641/95A priority patent/AU684218B2/en
Priority to SI9520078A priority patent/SI9520078B/sl
Priority to ES95927699T priority patent/ES2126919T3/es
Priority to DK95927699T priority patent/DK0773938T3/da
Priority to ROA200000502A priority patent/RO116549B1/ro
Priority to EP95927699A priority patent/EP0773938B1/en
Priority to RU97102722A priority patent/RU2134688C1/ru
Priority to HU9700206A priority patent/HU222496B1/hu
Priority to AT95927699T priority patent/ATE176464T1/de
Priority to CZ1997199A priority patent/CZ293076B6/cs
Priority to US08/505,924 priority patent/US5756776A/en
Publication of ITMI941592A1 publication Critical patent/ITMI941592A1/it
Priority to NO19970296A priority patent/NO315116B1/no
Priority to BG101165A priority patent/BG62851B1/bg
Priority to FI970271A priority patent/FI120398B/fi
Application granted granted Critical
Publication of IT1274356B publication Critical patent/IT1274356B/it
Priority to HK98112903A priority patent/HK1011687A1/xx
Priority to GR990400393T priority patent/GR3029309T3/el
Priority to CN00129055A priority patent/CN1130356C/zh
Priority to CN00129054A priority patent/CN1120161C/zh
Priority to CN00129056A priority patent/CN1128795C/zh

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invenzione riguarda nuovi derivati ottenibili per ossidazione e riduzione stereospecifica della 10-deacetilbaccatina III e successiva esterificazione con catena isoserinica variamente sostituita per l'ottenimento di analoghi del tassolo. I prodotti dell'invenzione sono dotati di attività citotossica ed antitumorale e possono essere somministrati per via iniettiva e/o per via orale quando opportunamente formulati.
ITMI941592A 1994-07-26 1994-07-26 Tassani semisintetici odtati di attivita' antitumorale IT1274356B (it)

Priority Applications (29)

Application Number Priority Date Filing Date Title
ITMI941592A IT1274356B (it) 1994-07-26 1994-07-26 Tassani semisintetici odtati di attivita' antitumorale
ROA200000502A RO116549B1 (ro) 1994-07-26 1995-07-21 Derivati de taxan, procedeu pentru prepararea acestora, intermediar pentru prepararea acestora si compozitie farmaceutica care ii contine
EP95927699A EP0773938B1 (en) 1994-07-26 1995-07-21 Semi-synthetic taxanes with anti-tumoural activity
CA002195844A CA2195844C (en) 1994-07-26 1995-07-21 Semi-synthetic taxanes with anti-tumoural activity
PCT/EP1995/002896 WO1996003394A1 (en) 1994-07-26 1995-07-21 Semi-synthetic taxanes with anti-tumoural activity
SK100-97A SK281526B6 (sk) 1994-07-26 1995-07-21 Semisyntetický taxán, spôsob jeho prípravy a medziprodukt, semisyntetický sekotaxán, spôsob jeho prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
KR1019970700442A KR100220490B1 (ko) 1994-07-26 1995-07-21 항암작용을 갖는 반합성 탁산유도체
DE69507702T DE69507702T2 (de) 1994-07-26 1995-07-21 Semisynthetisch taxal derivate mit antitumor wirkung
CN95194333A CN1073105C (zh) 1994-07-26 1995-07-21 具有抗肿瘤活性的半合成紫杉烷
PL95318289A PL187579B1 (pl) 1994-07-26 1995-07-21 Nowe półsyntetyczne taksany, sposób wytwarzania półsyntetycznych taksanów, nowe związki pośrednie, nowe półsyntetyczne seko-taksany, sposób wytwarzania półsyntetycznych seko-taksanów i przeciwnowotworowe kompozycje farmaceutyczne
AU31641/95A AU684218B2 (en) 1994-07-26 1995-07-21 Semi-synthetic taxanes with anti-tumoural activity
SI9520078A SI9520078B (sl) 1994-07-26 1995-07-21 Polsintetski taksani z antitumorsko aktivnostjo
ES95927699T ES2126919T3 (es) 1994-07-26 1995-07-21 Taxanos semisinteticos con actividad antitumoral.
DK95927699T DK0773938T3 (da) 1994-07-26 1995-07-21 Semi-syntetiske taxaner med anti-tumoraktivitet
RO97-00125A RO115875B1 (ro) 1994-07-26 1995-07-21 Derivati de taxan, procedeu pentru prepararea acestora, intermediar pentru prepararea acestora si compozitie farmaceutica care ii contine
RU97102722A RU2134688C1 (ru) 1994-07-26 1995-07-21 Полусинтетический таксан, промежуточные соединения, способы получения и фармацевтическая композиция
CZ1997199A CZ293076B6 (cs) 1994-07-26 1995-07-21 Polosyntetické taxany, způsob jejich výroby, farmaceutické prostředky s jejich obsahem a meziprodukty pro jejich výrobu
JP8505456A JP2986550B2 (ja) 1994-07-26 1995-07-21 抗腫瘍活性を有する半合成タキサン
AT95927699T ATE176464T1 (de) 1994-07-26 1995-07-21 Semisynthetisch taxal derivate mit antitumor wirkung
HU9700206A HU222496B1 (hu) 1994-07-26 1995-07-21 Félszintetikus taxánszármazékok, eljárás ezek előállítására, valamint ezeket tartalmazó gyógyászati készítmények
US08/505,924 US5756776A (en) 1994-07-26 1995-07-24 Semi-synthetic taxanes with anti-tumoural activity
NO19970296A NO315116B1 (no) 1994-07-26 1997-01-23 Semi-syntetiske taksaner med anti-tumoral aktivitet
BG101165A BG62851B1 (bg) 1994-07-26 1997-01-23 Полусинтетични таксани с противотуморно действие, метод за получаване и приложението им
FI970271A FI120398B (fi) 1994-07-26 1997-01-23 Puolisynteettiset taksaanit, joilla on kasvaimia torjuvaa vaikutusta, sekä niiden valmistusmenetelmät, välituotteet ja farmaseuttiset koostumukset
HK98112903A HK1011687A1 (en) 1994-07-26 1998-12-07 Semi-synthetic taxanes with anti-tumoural activity
GR990400393T GR3029309T3 (en) 1994-07-26 1999-02-09 Semi-synthetic taxanes with anti-tumoural activity
CN00129055A CN1130356C (zh) 1994-07-26 2000-09-29 具有抗肿瘤活性的半合成断紫杉烷
CN00129054A CN1120161C (zh) 1994-07-26 2000-09-29 具有抗肿瘤活性的半合成紫杉烷
CN00129056A CN1128795C (zh) 1994-07-26 2000-09-29 具有抗肿瘤活性的半合成紫杉烷

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI941592A IT1274356B (it) 1994-07-26 1994-07-26 Tassani semisintetici odtati di attivita' antitumorale

Publications (3)

Publication Number Publication Date
ITMI941592A0 ITMI941592A0 (it) 1994-07-26
ITMI941592A1 ITMI941592A1 (it) 1996-01-26
IT1274356B true IT1274356B (it) 1997-07-17

Family

ID=11369367

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI941592A IT1274356B (it) 1994-07-26 1994-07-26 Tassani semisintetici odtati di attivita' antitumorale

Country Status (1)

Country Link
IT (1) IT1274356B (it)

Also Published As

Publication number Publication date
ITMI941592A0 (it) 1994-07-26
ITMI941592A1 (it) 1996-01-26

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970729