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IT1243745B - Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione. - Google Patents

Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.

Info

Publication number
IT1243745B
IT1243745B IT02176690A IT2176690A IT1243745B IT 1243745 B IT1243745 B IT 1243745B IT 02176690 A IT02176690 A IT 02176690A IT 2176690 A IT2176690 A IT 2176690A IT 1243745 B IT1243745 B IT 1243745B
Authority
IT
Italy
Prior art keywords
transdermal therapeutic
therapeutic compositions
preparation
compositions containing
promoting agent
Prior art date
Application number
IT02176690A
Other languages
English (en)
Other versions
IT9021766A0 (it
IT9021766A1 (it
Inventor
Fabio Carli
Luca Doretti
Original Assignee
Vectorpharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma Int filed Critical Vectorpharma Int
Publication of IT9021766A0 publication Critical patent/IT9021766A0/it
Priority to IT02176690A priority Critical patent/IT1243745B/it
Priority to EP91117639A priority patent/EP0481443B1/en
Priority to DE69126270T priority patent/DE69126270T2/de
Priority to ES91117639T priority patent/ES2104642T3/es
Priority to DK91117639.4T priority patent/DK0481443T3/da
Priority to AT91117639T priority patent/ATE153538T1/de
Priority to US07/777,123 priority patent/US5582836A/en
Publication of IT9021766A1 publication Critical patent/IT9021766A1/it
Application granted granted Critical
Publication of IT1243745B publication Critical patent/IT1243745B/it
Priority to GR970402206T priority patent/GR3024567T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT02176690A 1990-10-17 1990-10-17 Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione. IT1243745B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT02176690A IT1243745B (it) 1990-10-17 1990-10-17 Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
DK91117639.4T DK0481443T3 (da) 1990-10-17 1991-10-15 Transdermale terapeutiske præparater
DE69126270T DE69126270T2 (de) 1990-10-17 1991-10-15 Transdermale therapeutische Zubereitungen
ES91117639T ES2104642T3 (es) 1990-10-17 1991-10-15 Composiciones terapeuticas transdermicas.
EP91117639A EP0481443B1 (en) 1990-10-17 1991-10-15 Transdermal therapeutic compositions
AT91117639T ATE153538T1 (de) 1990-10-17 1991-10-15 Transdermale therapeutische zubereitungen
US07/777,123 US5582836A (en) 1990-10-17 1991-10-16 Transdermal therapeutic compositions
GR970402206T GR3024567T3 (en) 1990-10-17 1997-08-28 Transdermal therapeutic compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02176690A IT1243745B (it) 1990-10-17 1990-10-17 Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.

Publications (3)

Publication Number Publication Date
IT9021766A0 IT9021766A0 (it) 1990-10-17
IT9021766A1 IT9021766A1 (it) 1992-04-17
IT1243745B true IT1243745B (it) 1994-06-21

Family

ID=11186565

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02176690A IT1243745B (it) 1990-10-17 1990-10-17 Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.

Country Status (8)

Country Link
US (1) US5582836A (it)
EP (1) EP0481443B1 (it)
AT (1) ATE153538T1 (it)
DE (1) DE69126270T2 (it)
DK (1) DK0481443T3 (it)
ES (1) ES2104642T3 (it)
GR (1) GR3024567T3 (it)
IT (1) IT1243745B (it)

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US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
EP0707465A4 (en) * 1993-07-08 1997-04-16 Cygnus Therapeutic Systems MONOLITHIC MATRIX TRANSDERMAL DELIVERY SYSTEM
WO1995001766A1 (en) * 1993-07-09 1995-01-19 Cygnus Therapeutic Systems Method and device for providing nicotine replacement therapy transdermally/transbuccally
DE4338414C1 (de) * 1993-11-10 1995-03-16 Linde Ag Verfahren zur Herstellung linearer Olefine
WO1996022084A2 (en) * 1995-01-19 1996-07-25 Cygnus, Inc. Polymer adhesive formulation containing sorbent particles
FR2735024B1 (fr) * 1995-06-08 1997-11-28 Sanofi Sa Dispositif d'administration cutanee d'un produit medicamenteux ou cosmetique.
ES2196208T3 (es) * 1996-03-09 2003-12-16 Nitto Denko Corp Preparacion percutanea adhesiva.
US5912009A (en) * 1996-10-30 1999-06-15 Theratech, Inc. Fatty acid esters of glycolic acid and its salts
US8679534B2 (en) * 1997-12-12 2014-03-25 Andrx Labs, Llc HMG-CoA reductase inhibitor extended release formulation
US6344218B1 (en) 1998-11-23 2002-02-05 The Procter & Gamble Company Skin deodorizing and santizing compositions
DE19906152B4 (de) * 1999-02-10 2005-02-10 Jenapharm Gmbh & Co. Kg Wirkstoffhaltige Laminate für Transdermalsysteme
US20040147534A1 (en) * 2003-01-23 2004-07-29 Foote Mary Ann Topical composition and method for treating occlusive wounds
DE10358747A1 (de) * 2003-12-12 2005-07-07 Lts Lohmann Therapie-Systeme Ag Darreichungsform basierend auf vernetzten hydrophilen Polymeren
US20050202073A1 (en) * 2004-03-09 2005-09-15 Mylan Technologies, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US9205062B2 (en) 2004-03-09 2015-12-08 Mylan Pharmaceuticals, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
EP1616581B1 (en) * 2004-06-18 2009-12-23 Nippon Shokubai Co., Ltd. Water absorbent resin composition and production method thereof
TWI353360B (en) 2005-04-07 2011-12-01 Nippon Catalytic Chem Ind Production process of polyacrylic acid (salt) wate
GB2431104A (en) * 2005-10-10 2007-04-18 Univ Greenwich Microgel particles grafted to a substrate
US7888422B2 (en) 2005-11-09 2011-02-15 Mylan Technologies Inc. Long-wearing removable pressure sensitive adhesive
GB0524958D0 (en) * 2005-12-07 2006-01-18 Pharmakodex Ltd Transdermal administration of active agents
TWI394789B (zh) 2005-12-22 2013-05-01 Nippon Catalytic Chem Ind 吸水性樹脂組成物及其製造方法、吸收性物品
EP1837348B9 (en) 2006-03-24 2020-01-08 Nippon Shokubai Co.,Ltd. Water-absorbing resin and method for manufacturing the same
DE102006026578B4 (de) 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
US9017301B2 (en) * 2007-09-04 2015-04-28 Mylan Technologies, Inc. Transdermal drug delivery systems comprising a coated release liner
US20110033515A1 (en) * 2009-08-04 2011-02-10 Rst Implanted Cell Technology Tissue contacting material
CN102548654A (zh) 2009-09-29 2012-07-04 株式会社日本触媒 颗粒状吸水剂及其制造方法
CN103124565A (zh) * 2010-08-06 2013-05-29 大日本住友制药株式会社 用于控制水溶性药物释放的药物制剂
DE102011090178A1 (de) 2011-12-30 2013-07-04 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation
US20180235903A1 (en) * 2015-03-13 2018-08-23 Amneal Pharmaceuticals Llc Fentanyl Transdermal Delivery System
KR20180127315A (ko) 2015-12-30 2018-11-28 코리움 인터네셔널, 인크. 장기 경피 투여를 위한 시스템 및 방법
JP7174632B2 (ja) 2016-06-23 2022-11-17 コリウム， インコーポレイテッド 親水性ドメインおよび疎水性ドメインならびに処置剤との接着剤マトリックス
KR102508993B1 (ko) * 2016-07-27 2023-03-10 코리움, 인크. 메만틴 경피 송달 시스템

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US4818540A (en) * 1985-02-25 1989-04-04 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
US5045319A (en) * 1985-02-25 1991-09-03 Rutgers, The State University Of New Jersey Transdermal dosage unit, system and process
US4615699A (en) * 1985-05-03 1986-10-07 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes
EP0241806A1 (en) * 1986-04-14 1987-10-21 Fujisawa Pharmaceutical Co., Ltd. Sustained-release transdermal delivery preparations
US4946870A (en) * 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
US5001139A (en) * 1987-06-12 1991-03-19 American Cyanamid Company Enchancers for the transdermal flux of nivadipine
IT1216570B (it) * 1988-04-08 1990-03-08 Vectorpharma Int Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione.
IT1230566B (it) * 1988-10-17 1991-10-28 Vectorpharma Int Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5002773A (en) * 1989-09-29 1991-03-26 Marion Merrell Dow Inc. Transdermal delivery of (+) (2S,3S)-3-acetoxy-8-chloro-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4-(5H)-one
US5051426A (en) * 1990-03-27 1991-09-24 Parnell Pharmaceuticals, Inc. Method for effecting withdrawal from drug dependency

Also Published As

Publication number Publication date
ATE153538T1 (de) 1997-06-15
ES2104642T3 (es) 1997-10-16
IT9021766A0 (it) 1990-10-17
US5582836A (en) 1996-12-10
IT9021766A1 (it) 1992-04-17
DE69126270T2 (de) 1997-12-04
EP0481443A1 (en) 1992-04-22
EP0481443B1 (en) 1997-05-28
DE69126270D1 (de) 1997-07-03
GR3024567T3 (en) 1997-12-31
DK0481443T3 (da) 1997-12-22

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971030