IT1227626B - Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione - Google Patents
Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazioneInfo
- Publication number
- IT1227626B IT1227626B IT8822770A IT2277088A IT1227626B IT 1227626 B IT1227626 B IT 1227626B IT 8822770 A IT8822770 A IT 8822770A IT 2277088 A IT2277088 A IT 2277088A IT 1227626 B IT1227626 B IT 1227626B
- Authority
- IT
- Italy
- Prior art keywords
- increased dissolution
- drugs
- procedure
- preparation
- increased
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/797—Lipid particle
- Y10S977/798—Lipid particle having internalized material
- Y10S977/799—Containing biological material
- Y10S977/801—Drug
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nanotechnology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Electroluminescent Light Sources (AREA)
- Control Of El Displays (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8822770A IT1227626B (it) | 1988-11-28 | 1988-11-28 | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
| YU02211/89A YU221189A (en) | 1988-11-28 | 1989-11-22 | Process for obtaining pharmaceutic compounds, with increased dissolving speed |
| PT92416A PT92416B (pt) | 1988-11-28 | 1989-11-27 | Processo de preparacao de drogas suportadas possuindo velocidade de dissolucao aumentada |
| KR1019890017219A KR900007398A (ko) | 1988-11-28 | 1989-11-27 | 증가된 용해속도를 갖는 지지된 약물 및 이의 제조방법 |
| HU896191A HU203468B (en) | 1988-11-28 | 1989-11-27 | Process for producing pharmaceutical compositions on carrier with improved solubility |
| AT89121865T ATE123940T1 (de) | 1988-11-28 | 1989-11-27 | Arzneimittel auf trägern mit erhöhter lösungsgeschwindigkeit und verfahren zu ihrer herstellung. |
| IL9245489A IL92454A (en) | 1988-11-28 | 1989-11-27 | Drugs with increased dissolution rate and their preparation |
| SU894742518A RU1837868C (ru) | 1988-11-28 | 1989-11-27 | Способ получени лекарственного средства на носителе с повышенной скоростью растворени |
| DE68923157T DE68923157T2 (de) | 1988-11-28 | 1989-11-27 | Arzneimittel auf Trägern mit erhöhter Lösungsgeschwindigkeit und Verfahren zu ihrer Herstellung. |
| EP89121865A EP0371431B1 (en) | 1988-11-28 | 1989-11-27 | Supported drugs with increased dissolution rate, and a process for their preparation |
| DK198905958A DK175684B1 (da) | 1988-11-28 | 1989-11-27 | Lægemiddel med forøget opløsningshastighed og indeholdende et bærestof samt fremgangsmåde til fremstilling af et sådant lægemiddel |
| ES89121865T ES2076192T3 (es) | 1988-11-28 | 1989-11-27 | Farmacos soportados con proporcion de disolucion incrementada, y un proceso para su preparacion. |
| CA002004064A CA2004064C (en) | 1988-11-28 | 1989-11-28 | Supported drugs with increased dissolution rate, and a process for theirpreparation |
| FI895693A FI895693A7 (fi) | 1988-11-28 | 1989-11-28 | Parantuneen liukoisuuden omaavia kantaja/lääkeainekoostumuksia ja menetelmä niiden valmistamiseksi |
| JP1308833A JP2823170B2 (ja) | 1988-11-28 | 1989-11-28 | 溶解率を向上した担体支持薬剤およびその製造方法 |
| US07/827,496 US5354560A (en) | 1988-11-28 | 1992-01-30 | Supported drugs with increased dissolution rate, and a process for their preparation |
| SU925052176A RU2097027C1 (ru) | 1988-11-28 | 1992-07-16 | Лекарственные препараты на носителе |
| US08/203,034 US5449521A (en) | 1988-11-28 | 1994-02-28 | Supported drugs with increased dissolution rate, and a process for their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8822770A IT1227626B (it) | 1988-11-28 | 1988-11-28 | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8822770A0 IT8822770A0 (it) | 1988-11-28 |
| IT1227626B true IT1227626B (it) | 1991-04-23 |
Family
ID=11200272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8822770A IT1227626B (it) | 1988-11-28 | 1988-11-28 | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US5354560A (it) |
| EP (1) | EP0371431B1 (it) |
| JP (1) | JP2823170B2 (it) |
| KR (1) | KR900007398A (it) |
| AT (1) | ATE123940T1 (it) |
| CA (1) | CA2004064C (it) |
| DE (1) | DE68923157T2 (it) |
| DK (1) | DK175684B1 (it) |
| ES (1) | ES2076192T3 (it) |
| FI (1) | FI895693A7 (it) |
| HU (1) | HU203468B (it) |
| IL (1) | IL92454A (it) |
| IT (1) | IT1227626B (it) |
| PT (1) | PT92416B (it) |
| RU (2) | RU1837868C (it) |
| YU (1) | YU221189A (it) |
Families Citing this family (109)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5569469A (en) * | 1984-10-16 | 1996-10-29 | Vectorpharma International, S.P.A. | Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate |
| IT1241088B (it) * | 1990-03-27 | 1993-12-29 | Chiesi Farma Spa | Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche |
| HU210921B (en) * | 1990-03-28 | 1995-09-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them |
| IT1246188B (it) * | 1990-07-27 | 1994-11-16 | Resa Farma | Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute. |
| IT1243745B (it) * | 1990-10-17 | 1994-06-21 | Vectorpharma Int | Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione. |
| US5552160A (en) * | 1991-01-25 | 1996-09-03 | Nanosystems L.L.C. | Surface modified NSAID nanoparticles |
| US5399363A (en) * | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| DE69231457T2 (de) * | 1991-06-21 | 2001-05-23 | Takeda Chemical Industries Ltd | Zyklodextrin-Zusammensetzung enthaltend Fumagillol-Derivate |
| EP0644755B1 (en) * | 1992-06-10 | 1997-03-19 | NanoSystems L.L.C. | Surface modified nsaid nanoparticles |
| IT1255462B (it) * | 1992-07-28 | 1995-11-02 | Grazia Maffione | Metodo di preparazione di composti di inclusione di nimesulide con ciclodestrine |
| AU660852B2 (en) * | 1992-11-25 | 1995-07-06 | Elan Pharma International Limited | Method of grinding pharmaceutical substances |
| HU213200B (en) | 1993-05-12 | 1997-03-28 | Chinoin Gyogyszer Es Vegyeszet | The cyclodextrin or cyclodextrin derivative cluster complexes of taxol, taxotere, or taxus, pharmaceutical preparations containing them and process for their production |
| GB9316580D0 (en) * | 1993-08-10 | 1993-09-29 | Smithkline Beecham Plc | Pharmaceutical composition |
| TW384224B (en) * | 1994-05-25 | 2000-03-11 | Nano Sys Llc | Method of preparing submicron particles of a therapeutic or diagnostic agent |
| US5684121A (en) * | 1994-12-06 | 1997-11-04 | Isp Investments Inc. | N-vinyl lactam polymer containing tablets of low friability and high rate of dissolution |
| US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
| US5759577A (en) * | 1995-01-17 | 1998-06-02 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
| US5518738A (en) * | 1995-02-09 | 1996-05-21 | Nanosystem L.L.C. | Nanoparticulate nsaid compositions |
| US5612053A (en) | 1995-04-07 | 1997-03-18 | Edward Mendell Co., Inc. | Controlled release insufflation carrier for medicaments |
| US6348469B1 (en) | 1995-04-14 | 2002-02-19 | Pharma Pass Llc | Solid compositions containing glipizide and polyethylene oxide |
| PT822808E (pt) * | 1995-04-20 | 2000-12-29 | Eurand Int | Composito com glicolato de amido e sodio como material de suporte e produtos seus derivados |
| US20050267302A1 (en) * | 1995-12-11 | 2005-12-01 | G.D. Searle & Co. | Eplerenone crystalline form exhibiting enhanced dissolution rate |
| US5686133A (en) * | 1996-01-31 | 1997-11-11 | Port Systems, L.L.C. | Water soluble pharmaceutical coating and method for producing coated pharmaceuticals |
| HUP9600758A2 (en) * | 1996-03-27 | 1998-03-02 | Cyclolab Ciklodextrin Kutato F | Diclofenac composition of diminished gastrointestinal irritation and enhanced biological resorption |
| US6048547A (en) * | 1996-04-15 | 2000-04-11 | Seth; Pawan | Process for manufacturing solid compositions containing polyethylene oxide and an active ingredient |
| WO1997039761A1 (en) | 1996-04-19 | 1997-10-30 | Alpha Therapeutic Corporation | A process for viral inactivation of lyophilized blood proteins |
| FR2757397B1 (fr) * | 1996-12-23 | 1999-03-05 | Mazal Pharma | Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree |
| US20050004049A1 (en) * | 1997-03-11 | 2005-01-06 | Elan Pharma International Limited | Novel griseofulvin compositions |
| US6451771B1 (en) | 1999-02-12 | 2002-09-17 | Nutramax Laboratories, Inc. | Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals |
| US20070141181A1 (en) | 1998-02-13 | 2007-06-21 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
| US6797289B2 (en) * | 1998-02-13 | 2004-09-28 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
| US6086242A (en) * | 1998-02-27 | 2000-07-11 | University Of Utah | Dual drive planetary mill |
| US6197347B1 (en) | 1998-06-29 | 2001-03-06 | Andrx Pharmaceuticals, Inc. | Oral dosage for the controlled release of analgesic |
| US6524620B2 (en) | 1998-07-20 | 2003-02-25 | Andrx Pharmaceuticals, Inc. | Diltiazem controlled release formulation and method of manufacture |
| FR2786100B1 (fr) * | 1998-11-24 | 2002-03-01 | Aventis Laboratoire | Nouvelle application therapeutique de la nicergoline |
| US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
| US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| UA74539C2 (en) | 1999-12-08 | 2006-01-16 | Pharmacia Corp | Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants) |
| US20030083493A1 (en) * | 1999-12-08 | 2003-05-01 | Barton Kathleen P. | Eplerenone drug substance having high phase purity |
| IL144757A0 (en) * | 1999-12-08 | 2002-06-30 | Pharmacia Corp | Eplerenone crystalline form |
| US7172769B2 (en) * | 1999-12-08 | 2007-02-06 | Pharmacia Corporation | Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect |
| US7108866B1 (en) | 1999-12-10 | 2006-09-19 | Biovall Laboratories International Srl | Chronotherapeutic diltiazem formulations and the administration thereof |
| US20060153914A1 (en) * | 1999-12-10 | 2006-07-13 | Biovail Laboratories International S.R.L. | Chronotherapeutic diltiazem formulations and the administration thereof |
| MY120279A (en) * | 2000-05-26 | 2005-09-30 | Pharmacia Corp | Use of a celecoxib composition for fast pain relief |
| US20020146409A1 (en) * | 2001-01-30 | 2002-10-10 | Herring Steven W. | Methods for stabilizing lyophilized blood proteins |
| RU2191577C1 (ru) * | 2001-04-19 | 2002-10-27 | Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" | Фармацевтическая противовоспалительная композиция и способ ее получения |
| BR0210516A (pt) | 2001-06-18 | 2004-10-05 | Noven Pharma | Distribuição intensificada de drogas em sistemas transdérmicos |
| CZ20033456A3 (en) * | 2001-06-22 | 2004-07-14 | Pfizer Products Inc. | Pharmaceutical compositions comprising adsorbates of amorphous drug |
| EP1269994A3 (en) * | 2001-06-22 | 2003-02-12 | Pfizer Products Inc. | Pharmaceutical compositions comprising drug and concentration-enhancing polymers |
| US8889182B2 (en) * | 2001-06-29 | 2014-11-18 | Aptalis Pharma Limited | Process of thermodynamical activation of water-insoluble drugs loaded into cross-linked polymers |
| US20030073609A1 (en) | 2001-06-29 | 2003-04-17 | Pinkerton Thomas C. | Enhanced pharmacokinetic profile of intradermally delivered substances |
| JP2005529060A (ja) * | 2001-09-25 | 2005-09-29 | ファルマシア コーポレイション | Ｎ−（２−ヒドロキシアセチル）−５−（４−ピペリヂル）−４−（４−ピリミヂニル）−３−（４−クロロフェニル）ピラゾールの固体形態 |
| RU2199307C1 (ru) * | 2001-12-24 | 2003-02-27 | Закрытое акционерное общество "Брынцалов-А" | Крем пироксифер, обладающий противовоспалительным и анальгезирующим действием |
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| RU2332425C2 (ru) * | 2002-09-06 | 2008-08-27 | Инсёрт Терапьютикс, Инк. | Полимеры на основе циклодекстрина для доставки терапевтических средств |
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| US9254294B2 (en) | 2003-02-24 | 2016-02-09 | Pharmaceutical Productions Inc. | Transmucosal hormone delivery system |
| US10172810B2 (en) | 2003-02-24 | 2019-01-08 | Pharmaceutical Productions, Inc. | Transmucosal ketamine delivery composition |
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| MXPA06001417A (es) * | 2003-08-04 | 2006-05-15 | Pfizer Prod Inc | Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas. |
| EA200800099A1 (ru) * | 2005-06-22 | 2008-06-30 | Элан Фарма Интернэшнл Лтд. | Композиции наночастиц мегестрола |
| BRPI0709409A2 (pt) | 2006-03-28 | 2011-07-12 | Javelin Pharmaceuticals Inc | composição farmacêutica e método para tratar um mamìfero necessitando de analgesia |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3079303A (en) * | 1958-12-11 | 1963-02-26 | Smith Kline French Lab | Basic tablet granulation and process of using same |
| NO98434A (it) * | 1959-04-30 | |||
| US3328256A (en) * | 1963-05-27 | 1967-06-27 | William E Gaunt | Spherical beads and their production |
| NL6414091A (nl) * | 1964-12-04 | 1966-06-06 | Organon Nv | Werkwijze voor het vloeibaar maken van poeders alsmede de aldus verkregen poeders |
| JPS5132719A (en) * | 1974-09-13 | 1976-03-19 | Yoshinobu Nakai | Iyakuhinnoshorihoho |
| US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| US4037794A (en) * | 1974-09-23 | 1977-07-26 | Dierks & Sohne | Granulation apparatus |
| DE2742442C3 (de) * | 1977-09-21 | 1980-03-06 | Balcke-Duerr Ag, 4030 Ratingen | Elastische Kupplung |
| JPS5849428A (ja) * | 1981-09-16 | 1983-03-23 | Takeda Chem Ind Ltd | 細粒剤の製造法 |
| DE3485000D1 (de) * | 1983-06-28 | 1991-10-10 | Takeda Chemical Industries Ltd | Gemahlene mischung. |
| DE3346123A1 (de) * | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
| GB8403359D0 (en) * | 1984-02-08 | 1984-03-14 | Erba Farmitalia | Pharmaceutical compositions |
| US4837031A (en) * | 1987-09-17 | 1989-06-06 | Mallinckrodt, Inc. | Compositions containing ibuprofen |
-
1988
- 1988-11-28 IT IT8822770A patent/IT1227626B/it active
-
1989
- 1989-11-22 YU YU02211/89A patent/YU221189A/xx unknown
- 1989-11-27 PT PT92416A patent/PT92416B/pt not_active IP Right Cessation
- 1989-11-27 DE DE68923157T patent/DE68923157T2/de not_active Expired - Fee Related
- 1989-11-27 EP EP89121865A patent/EP0371431B1/en not_active Expired - Lifetime
- 1989-11-27 RU SU894742518A patent/RU1837868C/ru active
- 1989-11-27 HU HU896191A patent/HU203468B/hu not_active IP Right Cessation
- 1989-11-27 KR KR1019890017219A patent/KR900007398A/ko not_active Withdrawn
- 1989-11-27 IL IL9245489A patent/IL92454A/en not_active IP Right Cessation
- 1989-11-27 DK DK198905958A patent/DK175684B1/da not_active IP Right Cessation
- 1989-11-27 ES ES89121865T patent/ES2076192T3/es not_active Expired - Lifetime
- 1989-11-27 AT AT89121865T patent/ATE123940T1/de not_active IP Right Cessation
- 1989-11-28 JP JP1308833A patent/JP2823170B2/ja not_active Expired - Fee Related
- 1989-11-28 CA CA002004064A patent/CA2004064C/en not_active Expired - Lifetime
- 1989-11-28 FI FI895693A patent/FI895693A7/fi not_active Application Discontinuation
-
1992
- 1992-01-30 US US07/827,496 patent/US5354560A/en not_active Expired - Fee Related
- 1992-07-16 RU SU925052176A patent/RU2097027C1/ru not_active IP Right Cessation
-
1994
- 1994-02-28 US US08/203,034 patent/US5449521A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK595889D0 (da) | 1989-11-27 |
| EP0371431A2 (en) | 1990-06-06 |
| HUT52366A (en) | 1990-07-28 |
| DE68923157T2 (de) | 1995-11-09 |
| FI895693A7 (fi) | 1990-05-29 |
| PT92416B (pt) | 1995-08-09 |
| US5354560A (en) | 1994-10-11 |
| CA2004064A1 (en) | 1990-05-28 |
| IL92454A (en) | 1994-06-24 |
| ES2076192T3 (es) | 1995-11-01 |
| RU1837868C (ru) | 1993-08-30 |
| DK175684B1 (da) | 2005-01-17 |
| HU203468B (en) | 1991-08-28 |
| CA2004064C (en) | 2000-02-08 |
| RU2097027C1 (ru) | 1997-11-27 |
| YU221189A (en) | 1991-06-30 |
| PT92416A (pt) | 1990-05-31 |
| IL92454A0 (en) | 1990-08-31 |
| DE68923157D1 (de) | 1995-07-27 |
| EP0371431B1 (en) | 1995-06-21 |
| IT8822770A0 (it) | 1988-11-28 |
| KR900007398A (ko) | 1990-06-01 |
| US5449521A (en) | 1995-09-12 |
| DK595889A (da) | 1990-05-29 |
| FI895693A0 (fi) | 1989-11-28 |
| ATE123940T1 (de) | 1995-07-15 |
| EP0371431A3 (en) | 1991-10-09 |
| JP2823170B2 (ja) | 1998-11-11 |
| HU896191D0 (en) | 1990-02-28 |
| JPH02184621A (ja) | 1990-07-19 |
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Legal Events
| Date | Code | Title | Description |
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| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950525 |