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IT1230566B - Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione - Google Patents

Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione

Info

Publication number
IT1230566B
IT1230566B IT8822336A IT2233688A IT1230566B IT 1230566 B IT1230566 B IT 1230566B IT 8822336 A IT8822336 A IT 8822336A IT 2233688 A IT2233688 A IT 2233688A IT 1230566 B IT1230566 B IT 1230566B
Authority
IT
Italy
Prior art keywords
increase
polymeric substances
soluble drugs
dissolution speed
little soluble
Prior art date
Application number
IT8822336A
Other languages
English (en)
Other versions
IT8822336A0 (it
Inventor
Maria Lucia Lovrecich
Original Assignee
Vectorpharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma Int filed Critical Vectorpharma Int
Publication of IT8822336A0 publication Critical patent/IT8822336A0/it
Priority to IT8822336A priority Critical patent/IT1230566B/it
Priority to YU01984/89A priority patent/YU198489A/xx
Priority to CA002000744A priority patent/CA2000744C/en
Priority to KR1019890014823A priority patent/KR0148006B1/ko
Priority to HU895330A priority patent/HU203481B/hu
Priority to DE89119241T priority patent/DE68907687T2/de
Priority to ES89119241T priority patent/ES2060715T3/es
Priority to EP89119241A priority patent/EP0364944B1/en
Priority to JP1270148A priority patent/JP2869103B2/ja
Priority to AT89119241T priority patent/ATE91622T1/de
Application granted granted Critical
Publication of IT1230566B publication Critical patent/IT1230566B/it
Priority to US07/952,474 priority patent/US5225192A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
IT8822336A 1988-10-17 1988-10-17 Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione IT1230566B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT8822336A IT1230566B (it) 1988-10-17 1988-10-17 Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione
YU01984/89A YU198489A (en) 1988-10-17 1989-10-13 Process for making hard dissolving compounds, supported on polymeric substances in a suitable form for increasing their dissolving speed
HU895330A HU203481B (en) 1988-10-17 1989-10-16 Process for producing pharmaceutical compositions of improved solubility
KR1019890014823A KR0148006B1 (ko) 1988-10-17 1989-10-16 용해속도를 증가시키기에 적합한 형태로 중합체 기재로 지지된 저가용성약제 및 이의 제조방법
CA002000744A CA2000744C (en) 1988-10-17 1989-10-16 Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate
DE89119241T DE68907687T2 (de) 1988-10-17 1989-10-17 In einer zur Erhöhung ihrer Löslichkeitsrate geeigneten Form auf polymere Substanzen aufgebrachte schwerlösliche Arzneistoffe.
ES89119241T ES2060715T3 (es) 1988-10-17 1989-10-17 Medicamentos escasamente solubles inmovilizados en substancias polimericas de una manera adecuada para incrementar su grado de disolucion.
EP89119241A EP0364944B1 (en) 1988-10-17 1989-10-17 Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate
JP1270148A JP2869103B2 (ja) 1988-10-17 1989-10-17 溶解率向上に適した形態のポリマー基剤に担持させた低溶解性薬剤およびその製造方法
AT89119241T ATE91622T1 (de) 1988-10-17 1989-10-17 In einer zur erhoehung ihrer loeslichkeitsrate geeigneten form auf polymere substanzen aufgebrachte schwerloesliche arzneistoffe.
US07/952,474 US5225192A (en) 1988-10-17 1992-09-28 Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8822336A IT1230566B (it) 1988-10-17 1988-10-17 Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione

Publications (2)

Publication Number Publication Date
IT8822336A0 IT8822336A0 (it) 1988-10-17
IT1230566B true IT1230566B (it) 1991-10-28

Family

ID=11194858

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8822336A IT1230566B (it) 1988-10-17 1988-10-17 Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione

Country Status (10)

Country Link
EP (1) EP0364944B1 (it)
JP (1) JP2869103B2 (it)
KR (1) KR0148006B1 (it)
AT (1) ATE91622T1 (it)
CA (1) CA2000744C (it)
DE (1) DE68907687T2 (it)
ES (1) ES2060715T3 (it)
HU (1) HU203481B (it)
IT (1) IT1230566B (it)
YU (1) YU198489A (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243745B (it) * 1990-10-17 1994-06-21 Vectorpharma Int Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
DE69231457T2 (de) * 1991-06-21 2001-05-23 Takeda Chemical Industries Ltd Zyklodextrin-Zusammensetzung enthaltend Fumagillol-Derivate
IT1252867B (it) * 1991-12-31 1995-06-28 Gentili Ist Spa Composizioni farmaceutiche contenenti progesterone ad elevata biodisponibilita'
AU722246B2 (en) * 1995-06-07 2000-07-27 Johnson & Johnson Consumer Products, Inc. Stable complexes of crosslinked polyvinylpyrrolidone and iodine and method of making the same
NL1003503C2 (nl) * 1996-07-04 1998-01-07 Negma Steba International Dev Farmaceutische samenstelling voor orale toediening.
US6287693B1 (en) * 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
ATE356637T1 (de) * 1998-12-04 2007-04-15 California Inst Of Techn Supramolekulare komplexe enthaltende arzneimittel
IT1318404B1 (it) * 2000-03-17 2003-08-25 Eurand Int Processo per la preparazione di formulazioni a rilascio accelerato conimpiego di fluidi compressi.
KR101268258B1 (ko) 2002-09-06 2013-05-31 인설트 테라페틱스, 인코퍼레이티드 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
SI1844765T1 (sl) 2003-06-13 2015-05-29 Skendi Finance, Ltd. Formulacija estradiola in progesterona s počasnim sproščanjem
DE102006026578B4 (de) 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス， インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
EP2224914B1 (en) 2007-09-14 2015-01-21 Wockhardt Limited Diacerein compositions
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
TWI473610B (zh) * 2008-10-28 2015-02-21 Twi Biotechnology Inc 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物
IE20100799A1 (en) 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
JP7699467B2 (ja) * 2021-05-21 2025-06-27 沢井製薬株式会社 タファミジス含有固形製剤及びその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU189534B (en) 1981-09-09 1986-07-28 Chinoin Rt.,Hu Process for producing new tablets containing cyclodextrin polymer as desintegrator
DE3326167A1 (de) * 1983-07-20 1985-02-21 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Feste arzneiformen, die als wirkstoff n-4-(2-(5-chlor-2-methoxybenzamido)-ethyl)-phenylsulfonyl-n'-cyclohexylharnstoff enthalten und verfahren zu ihrer herstellung
IE63321B1 (en) * 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system

Also Published As

Publication number Publication date
JPH02149513A (ja) 1990-06-08
EP0364944A1 (en) 1990-04-25
ATE91622T1 (de) 1993-08-15
ES2060715T3 (es) 1994-12-01
DE68907687D1 (de) 1993-08-26
HUT52398A (en) 1990-07-28
CA2000744C (en) 1999-12-07
JP2869103B2 (ja) 1999-03-10
CA2000744A1 (en) 1990-04-17
EP0364944B1 (en) 1993-07-21
HU895330D0 (en) 1990-01-28
YU198489A (en) 1991-08-31
HU203481B (en) 1991-08-28
KR0148006B1 (ko) 1998-08-17
IT8822336A0 (it) 1988-10-17
DE68907687T2 (de) 1993-10-28
KR900005960A (ko) 1990-05-07

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940316