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ES2060715T3 - Medicamentos escasamente solubles inmovilizados en substancias polimericas de una manera adecuada para incrementar su grado de disolucion. - Google Patents

Medicamentos escasamente solubles inmovilizados en substancias polimericas de una manera adecuada para incrementar su grado de disolucion.

Info

Publication number
ES2060715T3
ES2060715T3 ES89119241T ES89119241T ES2060715T3 ES 2060715 T3 ES2060715 T3 ES 2060715T3 ES 89119241 T ES89119241 T ES 89119241T ES 89119241 T ES89119241 T ES 89119241T ES 2060715 T3 ES2060715 T3 ES 2060715T3
Authority
ES
Spain
Prior art keywords
dissolution
scarly
immobilized
degree
increase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89119241T
Other languages
English (en)
Inventor
Mara Lucia Lovrecich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vectorpharma International SpA
Original Assignee
Vectorpharma International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma International SpA filed Critical Vectorpharma International SpA
Application granted granted Critical
Publication of ES2060715T3 publication Critical patent/ES2060715T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DICHO MEDICAMENTO ES INCORPORADO A PARTICULAS DE UN POLIMERO LIGADO EN CRUZ, EL CUAL ES DILATABLE EN AGUA PERO NO SOLUBLE, Y EL PRODUCTO OBTENIDO ES LLEVADO A CONTACTAR CON UN DISOLVENTE CAPAZ DE DILATAR EL POLIMERO. EL PRODUCTO OBTENIDO POR ESTE TRATAMIENTO ES DESPUES SECADO AL VACIO Y TIENE UN PORCENTAJE DE DISOLUCION CONSIDERABLEMENTE MAYOR QUE EL MEDICAMENTO PURO.
ES89119241T 1988-10-17 1989-10-17 Medicamentos escasamente solubles inmovilizados en substancias polimericas de una manera adecuada para incrementar su grado de disolucion. Expired - Lifetime ES2060715T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8822336A IT1230566B (it) 1988-10-17 1988-10-17 Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione

Publications (1)

Publication Number Publication Date
ES2060715T3 true ES2060715T3 (es) 1994-12-01

Family

ID=11194858

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89119241T Expired - Lifetime ES2060715T3 (es) 1988-10-17 1989-10-17 Medicamentos escasamente solubles inmovilizados en substancias polimericas de una manera adecuada para incrementar su grado de disolucion.

Country Status (10)

Country Link
EP (1) EP0364944B1 (es)
JP (1) JP2869103B2 (es)
KR (1) KR0148006B1 (es)
AT (1) ATE91622T1 (es)
CA (1) CA2000744C (es)
DE (1) DE68907687T2 (es)
ES (1) ES2060715T3 (es)
HU (1) HU203481B (es)
IT (1) IT1230566B (es)
YU (1) YU198489A (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243745B (it) * 1990-10-17 1994-06-21 Vectorpharma Int Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
DE69231457T2 (de) * 1991-06-21 2001-05-23 Takeda Chemical Industries Ltd Zyklodextrin-Zusammensetzung enthaltend Fumagillol-Derivate
IT1252867B (it) * 1991-12-31 1995-06-28 Gentili Ist Spa Composizioni farmaceutiche contenenti progesterone ad elevata biodisponibilita'
AU722246B2 (en) * 1995-06-07 2000-07-27 Johnson & Johnson Consumer Products, Inc. Stable complexes of crosslinked polyvinylpyrrolidone and iodine and method of making the same
NL1003503C2 (nl) * 1996-07-04 1998-01-07 Negma Steba International Dev Farmaceutische samenstelling voor orale toediening.
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
WO2000033885A1 (en) * 1998-12-04 2000-06-15 California Institute Of Technology Supramolecular complexes containing therapeutic agents
IT1318404B1 (it) * 2000-03-17 2003-08-25 Eurand Int Processo per la preparazione di formulazioni a rilascio accelerato conimpiego di fluidi compressi.
ATE533513T1 (de) 2002-09-06 2011-12-15 Cerulean Pharma Inc Polymere auf basis von cyclodextrin zur verabreichung von an diese kovalent gebundene arzneimittel
PL1820494T3 (pl) 2003-06-13 2010-07-30 Skendi Finance Ltd Mikrocząstki składające się z estradiolu i cholesterolu
DE102006026578B4 (de) 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
EP3207921A1 (en) 2007-09-14 2017-08-23 Wockhardt Limited Rhein or diacerein compositions
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
TWI473610B (zh) * 2008-10-28 2015-02-21 Twi Biotechnology Inc 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物
IE20100799A1 (en) 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
JP7699467B2 (ja) * 2021-05-21 2025-06-27 沢井製薬株式会社 タファミジス含有固形製剤及びその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU189534B (en) 1981-09-09 1986-07-28 Chinoin Rt.,Hu Process for producing new tablets containing cyclodextrin polymer as desintegrator
DE3326167A1 (de) * 1983-07-20 1985-02-21 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Feste arzneiformen, die als wirkstoff n-4-(2-(5-chlor-2-methoxybenzamido)-ethyl)-phenylsulfonyl-n'-cyclohexylharnstoff enthalten und verfahren zu ihrer herstellung
IE63321B1 (en) * 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system

Also Published As

Publication number Publication date
DE68907687D1 (de) 1993-08-26
KR0148006B1 (ko) 1998-08-17
IT8822336A0 (it) 1988-10-17
HUT52398A (en) 1990-07-28
IT1230566B (it) 1991-10-28
HU203481B (en) 1991-08-28
CA2000744A1 (en) 1990-04-17
HU895330D0 (en) 1990-01-28
EP0364944A1 (en) 1990-04-25
YU198489A (en) 1991-08-31
KR900005960A (ko) 1990-05-07
DE68907687T2 (de) 1993-10-28
JP2869103B2 (ja) 1999-03-10
JPH02149513A (ja) 1990-06-08
CA2000744C (en) 1999-12-07
ATE91622T1 (de) 1993-08-15
EP0364944B1 (en) 1993-07-21

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