IT1240765B - Composizioni farmaceutiche a base di ciclosporine. - Google Patents

Composizioni farmaceutiche a base di ciclosporine.

Info

Publication number: IT1240765B
Authority: IT; Italy
Prior art keywords: pharmaceutical compositions; cyclosporine; cyclosporine pharmaceutical; compositions; pharmaceutical
Prior art date: 1989-02-20

Application number

IT47650A

Other languages

English (en)

Other versions

IT9047650A1 (it

IT9047650A0 (it

Inventor

Ulrich Posanski

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-20

Filing date

1990-02-20

Publication date

1993-12-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10651981&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1240765(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-02-20 Application filed by Sandoz Ag filed Critical Sandoz Ag

1990-02-20 Publication of IT9047650A0 publication Critical patent/IT9047650A0/it

1990-08-21 Publication of IT9047650A1 publication Critical patent/IT9047650A1/it

1993-12-17 Application granted granted Critical

1993-12-17 Publication of IT1240765B publication Critical patent/IT1240765B/it

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IT47650A 1989-02-20 1990-02-20 Composizioni farmaceutiche a base di ciclosporine. IT1240765B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898903804A GB8903804D0 (en)	1989-02-20	1989-02-20	Improvements in or relating to organic compounds

Publications (3)

Publication Number	Publication Date
IT9047650A0 IT9047650A0 (it)	1990-02-20
IT9047650A1 IT9047650A1 (it)	1990-08-21
IT1240765B true IT1240765B (it)	1993-12-17

Family

ID=10651981

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT47650A IT1240765B (it)	1989-02-20	1990-02-20	Composizioni farmaceutiche a base di ciclosporine.

Country Status (9)

Country	Link
JP (1)	JPH0611703B2 (it)
BE (1)	BE1005236A3 (it)
CH (1)	CH680650A5 (it)
CY (1)	CY1886A (it)
DE (1)	DE4005190A1 (it)
FR (1)	FR2643262B1 (it)
GB (2)	GB8903804D0 (it)
HK (1)	HK149595A (it)
IT (1)	IT1240765B (it)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5639724A (en)	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
GB8904182D0 (en) *	1989-02-23	1989-04-05	Glaxo Canada	Pharmaceutical compositions
HU208491B (en) *	1990-11-27	1993-11-29	Gyogyszerkutato Intezet	Process for producing oral pharmaceutical composition containing cyclosporin
AU688920B2 (en) *	1991-06-27	1998-03-19	Novartis Ag	Transesterified corn oil products
US6262022B1 (en)	1992-06-25	2001-07-17	Novartis Ag	Pharmaceutical compositions containing cyclosporin as the active agent
IL102236A0 (en) *	1991-06-27	1993-01-14	Ltt Inst Co Ltd	Topical preparations containing cyclosporin
GB9113872D0 (en) *	1991-06-27	1991-08-14	Sandoz Ag	Improvements in or relating to organic compounds
ES2098739T3 (es)	1992-05-13	1997-05-01	Sandoz Ltd	Composiciones oftalmicas conteniendo una cyclosporin.
US5759566A (en) *	1992-07-28	1998-06-02	Poli Industria Chimica Spa	Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents
EP0589843B1 (en) *	1992-09-25	2001-11-28	Novartis AG	Pharmaceutical compositions containing cyclosporins
DK0697881T3 (da) †	1993-04-20	2002-10-07	Novartis Ag	Nye farmaceutiske præparater til oral indgivelse indeholdende cyclosporin
DE4412201A1 (de) *	1993-04-20	1994-11-10	Rentschler Arzneimittel	Neue pharmazeutische Zubereitungen zur oralen Verabreichung enthaltend Cyclosporin
NZ247516A (en) *	1993-04-28	1995-02-24	Bernard Charles Sherman	Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant
DE4322826A1 (de) *	1993-07-08	1995-01-12	Galenik Labor Freiburg Gmbh	Pharmazeutisches Präparat
DE4340781C3 (de) *	1993-11-30	2000-01-27	Novartis Ag	Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung
US5891846A (en) *	1994-02-17	1999-04-06	Shiseido Company, Ltd.	Cyclosporin-containing emulsion composition
EP0694308A4 (en) *	1994-02-17	1997-09-10	Shiseido Co Ltd	CYCLOSPORIN EMULSION COMPOSITION
GB9405304D0 (en) *	1994-03-16	1994-04-27	Scherer Ltd R P	Delivery systems for hydrophobic drugs
US5474979A (en) *	1994-05-17	1995-12-12	Allergan, Inc.	Nonirritating emulsions for sensitive tissue
ES2177652T3 (es)	1994-11-03	2002-12-16	Novartis Ag	Nuevas formas de preparacion de ciclosporina para la aplicacion oral con composicion simple y alta biodisponibilidad, y procedimiento para su obtencion.
US5603951A (en) *	1994-11-09	1997-02-18	Hanmi Pharm. Ind. Co., Ltd.	Cyclosporin-containing soft capsule compositions
KR0167613B1 (ko) *	1994-12-28	1999-01-15	한스 루돌프 하우스, 니콜 케르커	사이클로스포린-함유 연질캅셀제 조성물
US5766629A (en) *	1995-08-25	1998-06-16	Sangstat Medical Corporation	Oral cyclosporin formulations
US5834017A (en) *	1995-08-25	1998-11-10	Sangstat Medical Corporation	Oral cyclopsporin formulations
US5962019A (en) *	1995-08-25	1999-10-05	Sangstat Medical Corporation	Oral cyclosporin formulations
US5827822A (en) *	1996-03-25	1998-10-27	Sangstat Medical Corporation	Cyclosporin a formulations as nanoparticles
DE19544507B4 (de)	1995-11-29	2007-11-15	Novartis Ag	Cyclosporin enthaltende Präparate
CZ288631B6 (cs) *	1996-01-18	2001-08-15	Galena, A. S.	Léčivé přípravky s obsahem cyklosporinu
US5858401A (en) *	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
RU2211047C2 (ru)	1997-01-30	2003-08-27	Новартис Аг	Желатиновые капсулы с твердым покрытием, включающие фармацевтические композиции, практически не содержащие масел
ATE286403T1 (de) *	1997-03-12	2005-01-15	Abbott Lab	Hydrophile binäre systeme zur verabreichung von cyclosporin
WO1998040051A1 (en) *	1997-03-12	1998-09-17	Abbott Laboratories	Lipophilic binary systems for the administration of lipophilic compounds
JP5005847B2 (ja)	1997-07-29	2012-08-22	ベーリンガー・インゲルハイム・インテルナツィオナール・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	親油性化合物用の自己乳化性処方
CA2294033C (en)	1997-07-29	2007-01-09	Pharmacia & Upjohn Company	Pharmaceutical composition for acidic lipophilic compounds in a form of a self-emulsifying formulation
US6008191A (en) *	1997-09-08	1999-12-28	Panacea Biotec Limited	Pharmaceutical compositions containing cyclosporin
US6187747B1 (en)	1997-09-08	2001-02-13	Panacea Biotech Limited	Pharmaceutical composition comprising cyclosporin
US6346511B1 (en)	1997-09-08	2002-02-12	Panacea Biotec Limited	Pharmaceutical composition comprising cyclosporin
US5981607A (en) *	1998-01-20	1999-11-09	Allergan	Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers
ID25908A (id) *	1998-03-06	2000-11-09	Novartis Ag	Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
DE19859910C2 (de) *	1998-12-23	2001-03-22	Ratiopharm Gmbh	Orales Arzneimittel
US6248363B1 (en) *	1999-11-23	2001-06-19	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
GB9912476D0 (en)	1999-05-28	1999-07-28	Novartis Ag	Organic compounds
WO2001032143A1 (en) *	1999-11-02	2001-05-10	Cipla Ltd.	A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and a process for preparation thereof
GB2362573A (en) *	2000-05-25	2001-11-28	Cipla Ltd	Cyclosporin formulation
EP1151755B1 (en) *	2000-05-04	2005-03-16	Panacea Biotec Limited	Pharmaceutical compositions comprising cyclosporin as active ingredient
DE10030378A1 (de) *	2000-06-21	2002-03-14	Audit Inst For Medical Service	Neue pharmazeutische Zusammensetzung zur topischen Anwendung von wasserunlöslichen und/oder schwer wasserlöslichen Wirkstoffen
US6979672B2 (en)	2002-12-20	2005-12-27	Polichem, S.A.	Cyclosporin-based pharmaceutical compositions
JP4381037B2 (ja)	2003-06-04	2009-12-09	花王株式会社	油脂組成物
US8673351B2 (en)	2005-03-21	2014-03-18	Ivax Pharmaceuticals S.R.O.	Crystallization inhibitor and its use in gelatin capsules
US8492369B2 (en)	2010-04-12	2013-07-23	Clarus Therapeutics Inc	Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
JP5887044B2 (ja)	2005-04-15	2016-03-16	クラルスセラピューティクス, インコーポレーテッドClarus Therapeutic, Inc.	疎水性薬物のドラッグデリバリーシステムとその組成物
FR2914188B1 (fr) *	2007-03-28	2012-06-22	Trophos	Nouvelle composition a base d'oxime de cholest-4-en-3-one
GB2451811A (en)	2007-08-09	2009-02-18	Ems Sa	Delivery composition for solubilising water-insoluble pharmaceutical active ingredients
US11304960B2 (en)	2009-01-08	2022-04-19	Chandrashekar Giliyar	Steroidal compositions
CA2690490C (en) *	2010-01-19	2012-06-26	Accucaps Industries Limited	Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
US20180153904A1 (en)	2010-11-30	2018-06-07	Lipocine Inc.	High-strength testosterone undecanoate compositions
US9034858B2 (en)	2010-11-30	2015-05-19	Lipocine Inc.	High-strength testosterone undecanoate compositions
US9358241B2 (en)	2010-11-30	2016-06-07	Lipocine Inc.	High-strength testosterone undecanoate compositions
US20120148675A1 (en)	2010-12-10	2012-06-14	Basawaraj Chickmath	Testosterone undecanoate compositions
WO2015108045A1 (ja) *	2014-01-16	2015-07-23	マルホ株式会社	経皮投与用外用剤
WO2016033556A1 (en)	2014-08-28	2016-03-03	Lipocine Inc.	BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
WO2016033549A2 (en)	2014-08-28	2016-03-03	Lipocine Inc.	(17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
EP3544614A4 (en)	2016-11-28	2020-08-05	Lipocine Inc.	ORAL TESTOSTERONE UNDECANOATE THERAPY
AU2019308326A1 (en)	2018-07-20	2021-03-18	Lipocine Inc.	Liver disease
CA3136485A1 (en)	2019-04-11	2020-10-15	R.P. Scherer Technologies, Llc	Formulation for oral delivery of proteins, peptides and small molecules with poor permeability

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI65914C (fi) *	1978-03-07	1984-08-10	Sandoz Ag	Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
CH641356A5 (en) *	1979-02-27	1984-02-29	Sandoz Ag	Pharmaceutical compositions containing cyclosporin
AU558155B2 (en) *	1982-02-01	1987-01-22	Sandoz Ltd.	Treating multiple sclerosis with dihydro-cyclosporin d

1989
- 1989-02-20 GB GB898903804A patent/GB8903804D0/en active Pending
1990
- 1990-02-16 CH CH504/90A patent/CH680650A5/de not_active IP Right Cessation
- 1990-02-16 GB GB9003616A patent/GB2228198B/en not_active Expired - Lifetime
- 1990-02-19 DE DE4005190A patent/DE4005190A1/de not_active Ceased
- 1990-02-19 BE BE9000181A patent/BE1005236A3/fr not_active IP Right Cessation
- 1990-02-19 JP JP2038168A patent/JPH0611703B2/ja not_active Expired - Lifetime
- 1990-02-19 FR FR9002086A patent/FR2643262B1/fr not_active Expired - Lifetime
- 1990-02-20 IT IT47650A patent/IT1240765B/it active IP Right Grant
1995
- 1995-09-21 HK HK149595A patent/HK149595A/xx not_active IP Right Cessation
1996
- 1996-04-05 CY CY188696A patent/CY1886A/xx unknown

Also Published As

Publication number	Publication date
FR2643262B1 (fr)	1993-06-11
GB9003616D0 (en)	1990-04-11
GB2228198A (en)	1990-08-22
HK149595A (en)	1995-09-29
CY1886A (en)	1996-04-05
DE4005190A1 (de)	1990-08-23
GB2228198B (en)	1992-12-16
IT9047650A1 (it)	1990-08-21
JPH0611703B2 (ja)	1994-02-16
BE1005236A3 (fr)	1993-06-08
IT9047650A0 (it)	1990-02-20
JPH02255623A (ja)	1990-10-16
CH680650A5 (it)	1992-10-15
GB8903804D0 (en)	1989-04-05
FR2643262A1 (fr)	1990-08-24

Publication	Publication Date	Title
IT1240765B (it)	1993-12-17	Composizioni farmaceutiche a base di ciclosporine.
IT8948369A0 (it)	1989-09-15	Composizioni farmaceutiche a base di ciclosporine
IT9047609A0 (it)	1990-02-08	Composizioni galeniche a base di ciclosporina.
FI901102A0 (fi)	1990-03-05	Farmaceutiska kompositioner.
FI922364A0 (fi)	1992-05-22	Farmaceutiska kompositioner.
IT8920486A0 (it)	1989-05-12	Composizioni farmaceutiche.
DE69115263D1 (de)	1996-01-18	Pharmazeutische zusammensetzungen.
DE68900991D1 (de)	1992-04-23	Cyclosporin-zusammensetzungen.
NO901838L (no)	1990-10-29	Emulgerbare pasticidiske faststoff-sammensetninger.
IT8820386A0 (it)	1988-04-29	Composizioni farmaceutiche orosolubili contenti acetilcisteina.
FI893643A0 (fi)	1989-08-01	Farmaceutiska kompositioner.
DE68924530D1 (de)	1995-11-16	Chipträger-sockel niedriger bauhöhe.
FR2661830B1 (fr)	1992-09-04	Nouvelle compositions pharmaceutiques a base de flavonoside.
FI923371A (fi)	1992-07-24	En farmaceutisk formulation.
IT8921722A0 (it)	1989-09-15	Composizioni farmaceutiche stabili a base di calcitonina.
DE3768109D1 (de)	1991-04-04	Pharmazeutische zusammensetzungen.
DE69003003D1 (de)	1993-10-07	Pharmazeutische Zusammensetzung.
IT8721670A0 (it)	1987-08-18	Composizioni farmaceutiche a basedi ottreotide.
IT8919844A0 (it)	1989-03-21	Composizioni farmaceutiche.
IT9021735A0 (it)	1990-10-12	Composizioni farmaceutiche a base di calcitonine
IT1229230B (it)	1991-07-26	Piperidinilimidazopiridine farmacologicamente attive.
IT8423550A0 (it)	1984-11-13	Composizioni farmaceutiche stabili a base di cefatrizina.
IT1230877B (it)	1991-11-08	Composizioni cosmetiche a base di mucoproteine.
IT8920556A0 (it)	1989-05-19	Composizioni cosmetiche a base di mucoproteine.
IT8820026A0 (it)	1988-03-30	Composizioni farmaceutiche adattivita' antineoplastica.

Legal Events

Date	Code	Title	Description
1993-12-17	0001	Granted
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970226