IT1177501B - Resinato di un acido carbossilico sosituito, procedimento per la sua preparazione, suo impiego e preparati farmaceutici che contengono questo - Google Patents

Resinato di un acido carbossilico sosituito, procedimento per la sua preparazione, suo impiego e preparati farmaceutici che contengono questo

Info

Publication number: IT1177501B
Authority: IT; Italy
Prior art keywords: resinate; procedure; contain; preparation; carboxylic acid
Prior art date: 1983-01-12

Application number

IT47527/84A

Other languages

English (en)

Other versions

IT8447527A0 (it

Inventor

Satish Chandra Khanna

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-01-12

Filing date

1984-01-10

Publication date

1987-08-26

1984-01-10 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1984-01-10 Publication of IT8447527A0 publication Critical patent/IT8447527A0/it

1987-08-26 Application granted granted Critical

1987-08-26 Publication of IT1177501B publication Critical patent/IT1177501B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/44—Preparation of metal salts or ammonium salts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Polymers & Plastics (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IT47527/84A 1983-01-12 1984-01-10 Resinato di un acido carbossilico sosituito, procedimento per la sua preparazione, suo impiego e preparati farmaceutici che contengono questo IT1177501B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH14783A CH655507B (it)	1983-01-12	1983-01-12

Publications (2)

Publication Number	Publication Date
IT8447527A0 IT8447527A0 (it)	1984-01-10
IT1177501B true IT1177501B (it)	1987-08-26

Family

ID=4180317

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT47527/84A IT1177501B (it)	1983-01-12	1984-01-10	Resinato di un acido carbossilico sosituito, procedimento per la sua preparazione, suo impiego e preparati farmaceutici che contengono questo

Country Status (41)

Country	Link
US (1)	US4510128A (it)
EP (1)	EP0122219B1 (it)
JP (1)	JPS59134759A (it)
KR (1)	KR900006747B1 (it)
AR (1)	AR240310A1 (it)
AT (2)	AT391467B (it)
AU (1)	AU570230B2 (it)
BE (1)	BE898649A (it)
CA (1)	CA1218077A (it)
CH (1)	CH655507B (it)
CS (1)	CS269954B2 (it)
DD (1)	DD218373A5 (it)
DE (2)	DE3474152D1 (it)
DK (1)	DK166683B1 (it)
DZ (1)	DZ593A1 (it)
EG (1)	EG16562A (it)
ES (1)	ES8504849A1 (it)
FI (1)	FI82682C (it)
FR (1)	FR2542735B1 (it)
GB (1)	GB2134529B (it)
GR (1)	GR79793B (it)
HK (1)	HK90390A (it)
HU (1)	HU190750B (it)
IE (1)	IE56545B1 (it)
IL (1)	IL70660A (it)
IT (1)	IT1177501B (it)
LU (1)	LU85171A1 (it)
MA (1)	MA20000A1 (it)
MC (1)	MC1564A1 (it)
MT (1)	MTP943B (it)
NL (1)	NL8400098A (it)
NO (1)	NO162862C (it)
NZ (1)	NZ206815A (it)
OA (1)	OA07628A (it)
PH (1)	PH21795A (it)
PL (1)	PL142737B1 (it)
PT (1)	PT77932B (it)
RO (1)	RO88481A (it)
SE (1)	SE457959B (it)
ZA (1)	ZA84212B (it)
ZW (1)	ZW484A1 (it)

Families Citing this family (42)

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CH664085A5 (de) *	1985-02-08	1988-02-15	Ciba Geigy Ag	Pharmazeutische praeparate mit analgetischer wirksamkeit, sowie deren herstellung.
ES8604955A1 (es) *	1985-11-08	1986-03-16	Covex Sa	Procedimiento para la preparacion de resinatos de la (-) eburnamenina-14-(15h)-ona
GB8730010D0 (en) *	1987-12-23	1988-02-03	Smith Kline French Lab	Compounds
US5230885A (en) *	1987-12-23	1993-07-27	Smith Kline & French Laboratories Limited	Polystyrene anion exchange polymer pharmaceutical composition
AU608114B2 (en) *	1987-12-23	1991-03-21	Smith Kline & French Laboratories Limited	Compounds
CH675537A5 (it) *	1988-03-25	1990-10-15	Ciba Geigy Ag
SE509029C2 (sv) *	1988-08-16	1998-11-30	Ss Pharmaceutical Co	Långtidsverkande diklofenak-natriumpreparat
US4960799A (en) *	1988-09-13	1990-10-02	Ciba-Geigy Corporation	Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
ES2054089T3 (es) *	1988-11-10	1994-08-01	Ciba Geigy Ag	Formulaciones orales liquidas.
CA2002492A1 (en) *	1988-11-11	1990-05-11	Sandra T. A. Malkowska	Pharmaceutical ion exchange resin composition
GB8911719D0 (en) *	1989-05-22	1989-07-05	Smith Kline French Lab	Compounds
GB8913700D0 (en) *	1989-06-14	1989-08-02	Smith Kline French Lab	Compounds
GB8913699D0 (en) *	1989-06-14	1989-08-02	Smith Kline French Lab	Compounds
US5079001A (en) *	1989-11-03	1992-01-07	Ciba-Geigy Corporation	Liquid oral formulation of diclofenac
GB8928278D0 (en) *	1989-12-14	1990-02-21	Smith Kline French Lab	Compounds
SE9004129D0 (sv) *	1990-12-21	1990-12-21	Pharmacia Lkb Biotech	Anion exchanger
EP0592569A1 (en) *	1991-07-03	1994-04-20	Sano Corporation	Composition and method for transdermal delivery of diclofenac
EP1250937B1 (en) *	2001-04-09	2009-05-13	Rohm And Haas Company	Controlled dissolution of active ingredients
US20020176842A1 (en) *	2001-04-09	2002-11-28	Lyn Hughes	Extended release of active ingredients
US20030180249A1 (en) *	2002-03-18	2003-09-25	Khanna Satish Chandra	Dosage forms for hygroscopic active ingredients
US20050036977A1 (en) *	2003-08-11	2005-02-17	Dilip Gole	Taste-masked resinate and preparation thereof
US20080095842A1 (en) *	2004-12-06	2008-04-24	Antarkar Amit K	Rapidly Disintegrating Taste Masked Compositions and a Process for Its Preparations
RU2435569C2 (ru)	2006-03-16	2011-12-10	Трис Фарма, Инк.	Композиции с модифицированным высвобождением, содержащие комплексы лекарственное вещество - ионообменная смола
US7799347B2 (en)	2006-09-07	2010-09-21	Chondrex Inc.	Endotoxin-adsorbent for the prevention and treatment of autoimmune diseases
AU2009298112B2 (en) *	2008-10-02	2015-11-12	University Of Pittsburgh - Of The Commonwealth System Of Higher Education	Administration of an adsorbent polymer for treatment of systemic inflammation
JP5968300B2 (ja)	2010-03-24	2016-08-10	ジャズ、ファーマシューティカルズ、インコーポレイテッドＪａｚｚＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃ．	高用量、水溶性及び吸湿性薬剤基質用の制御放出性剤形
EP2884961B1 (en)	2012-08-15	2019-03-06	Tris Pharma Inc.	Methylphenidate extended release chewable tablet
US10398662B1 (en)	2015-02-18	2019-09-03	Jazz Pharma Ireland Limited	GHB formulation and method for its manufacture
US11590228B1 (en)	2015-09-08	2023-02-28	Tris Pharma, Inc	Extended release amphetamine compositions
US12186296B1 (en)	2016-07-22	2025-01-07	Flamel Ireland Limited	Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11986451B1 (en)	2016-07-22	2024-05-21	Flamel Ireland Limited	Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
UY37341A (es)	2016-07-22	2017-11-30	Flamel Ireland Ltd	Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US11504347B1 (en)	2016-07-22	2022-11-22	Flamel Ireland Limited	Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en)	2016-07-22	2023-03-14	Flamel Ireland Limited	Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602513B1 (en)	2016-07-22	2023-03-14	Flamel Ireland Limited	Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US20180263936A1 (en)	2017-03-17	2018-09-20	Jazz Pharmaceuticals Ireland Limited	Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
US11590081B1 (en)	2017-09-24	2023-02-28	Tris Pharma, Inc	Extended release amphetamine tablets
CA3115122A1 (en)	2018-11-19	2020-05-28	Jazz Pharmaceuticals Ireland Limited	Alcohol-resistant drug formulations
CN113473980A (zh)	2019-03-01	2021-10-01	弗拉梅尔爱尔兰有限公司	在进食状态下具有改善的药代动力学的γ-羟基丁酸酯组合物
TW202139986A (zh)	2020-02-21	2021-11-01	愛爾蘭商爵士製藥愛爾蘭有限責任公司	治療原發性嗜睡症之方法
US11779557B1 (en)	2022-02-07	2023-10-10	Flamel Ireland Limited	Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11583510B1 (en)	2022-02-07	2023-02-21	Flamel Ireland Limited	Methods of administering gamma hydroxybutyrate formulations after a high-fat meal

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GB857193A (en) *	1957-03-14	1960-12-29	Clinical Products Ltd	Resin-drug compounds
GB823000A (en) *	1957-10-03	1959-11-04	Clinical Products Ltd	Resin-drug compounds
GB869149A (en) *	1958-09-16	1961-05-31	Clinical Products Ltd	Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substances
US3316282A (en) *	1965-02-08	1967-04-25	Squibb & Sons Inc	Anion exchange resin complex of a cycloborate ester of a steroid
FI49600C (fi) *	1967-12-20	1975-08-11	Ciba Geigy Ag	Menetelmä substituoitujen fenyylietikkahappojen ja näiden suolojen val mistamiseksi.
CH519476A (de) *	1968-03-30	1972-02-29	Hoechst Ag	Verfahren zur Herstellung von Salzen von Acylamino-alkylbenzolsulfonyl-harnstoffen mit Anionenaustauschern
US3926864A (en) *	1971-06-21	1975-12-16	Ionics	Ion exchange membranes having a macroporous surface area
GB1423694A (en) *	1973-07-10	1976-02-04	Beecham Group Ltd	Pharmaceutical compositions
US4058491A (en) *	1975-02-11	1977-11-15	Plastomedical Sciences, Inc.	Cationic hydrogels based on heterocyclic N-vinyl monomers
FR2352547A1 (fr) *	1976-05-25	1977-12-23	Viridis Ets	Nouvelle resine anionique a action hypocholesterolemiante, son procede de preparation et compositions therapeutiques la contenant
US4217421A (en) *	1977-06-27	1980-08-12	Rohm And Haas Company	Anion exchange resins prepared from crosslinked polystyrenesulfonylchloride
US4380590A (en) *	1978-09-19	1983-04-19	Rohm And Haas Company	Emulsion copolymer cation exchange resins
IT1106718B (it) *	1978-12-21	1985-11-18	Alfa Farmaceutici Spa	Composizioni a base di resine anioniche salificate farmacologicamente attive
US4207399A (en) *	1979-03-14	1980-06-10	Rohm And Haas Company	Methylquinoline high polymer based on quaternary ammonium polymers
US4302548A (en) *	1980-05-22	1981-11-24	Rohm And Haas Company	Production of ion exchange resins, the resins so produced and ion exchange processes using them

1983
- 1983-01-12 CH CH14783A patent/CH655507B/de not_active IP Right Cessation
1984
- 1984-01-02 AT AT0000784A patent/AT391467B/de not_active IP Right Cessation
- 1984-01-05 MT MT943A patent/MTP943B/xx unknown
- 1984-01-06 AT AT84810008T patent/ATE37378T1/de not_active IP Right Cessation
- 1984-01-06 DE DE8484810008T patent/DE3474152D1/de not_active Expired
- 1984-01-06 GB GB08400251A patent/GB2134529B/en not_active Expired
- 1984-01-06 MA MA20221A patent/MA20000A1/fr unknown
- 1984-01-06 EP EP84810008A patent/EP0122219B1/de not_active Expired
- 1984-01-06 US US06/568,976 patent/US4510128A/en not_active Expired - Lifetime
- 1984-01-09 FI FI840069A patent/FI82682C/fi not_active IP Right Cessation
- 1984-01-09 CS CS84178A patent/CS269954B2/cs unknown
- 1984-01-09 RO RO84113260A patent/RO88481A/ro unknown
- 1984-01-09 PT PT77932A patent/PT77932B/pt unknown
- 1984-01-09 DE DE19843400491 patent/DE3400491A1/de active Granted
- 1984-01-10 ZW ZW4/84A patent/ZW484A1/xx unknown
- 1984-01-10 ES ES528770A patent/ES8504849A1/es not_active Expired
- 1984-01-10 IT IT47527/84A patent/IT1177501B/it active
- 1984-01-10 GR GR73478A patent/GR79793B/el unknown
- 1984-01-10 DD DD84259312A patent/DD218373A5/de not_active IP Right Cessation
- 1984-01-10 MC MC841684A patent/MC1564A1/xx unknown
- 1984-01-10 DZ DZ847047A patent/DZ593A1/fr active
- 1984-01-10 FR FR8400288A patent/FR2542735B1/fr not_active Expired
- 1984-01-10 PL PL1984245656A patent/PL142737B1/pl unknown
- 1984-01-10 SE SE8400098A patent/SE457959B/sv not_active IP Right Cessation
- 1984-01-10 AR AR295384A patent/AR240310A1/es active
- 1984-01-10 OA OA58200A patent/OA07628A/xx unknown
- 1984-01-10 CA CA000445018A patent/CA1218077A/en not_active Expired
- 1984-01-11 IE IE49/84A patent/IE56545B1/en not_active IP Right Cessation
- 1984-01-11 NO NO840090A patent/NO162862C/no not_active IP Right Cessation
- 1984-01-11 IL IL70660A patent/IL70660A/xx not_active IP Right Cessation
- 1984-01-11 ZA ZA84212A patent/ZA84212B/xx unknown
- 1984-01-11 DK DK011884A patent/DK166683B1/da not_active IP Right Cessation
- 1984-01-11 HU HU8473A patent/HU190750B/hu unknown
- 1984-01-11 AU AU23230/84A patent/AU570230B2/en not_active Expired
- 1984-01-11 NZ NZ206815A patent/NZ206815A/en unknown
- 1984-01-11 NL NL8400098A patent/NL8400098A/nl not_active Application Discontinuation
- 1984-01-11 LU LU85171A patent/LU85171A1/de unknown
- 1984-01-11 PH PH30094A patent/PH21795A/en unknown
- 1984-01-11 BE BE0/212185A patent/BE898649A/fr not_active IP Right Cessation
- 1984-01-11 JP JP59002106A patent/JPS59134759A/ja active Granted
- 1984-01-11 KR KR1019840000085A patent/KR900006747B1/ko not_active IP Right Cessation
- 1984-01-14 EG EG26/84A patent/EG16562A/xx active
1990
- 1990-11-01 HK HK903/90A patent/HK90390A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2542735A1 (fr)	1984-09-21
AU2323084A (en)	1984-07-19
DK11884D0 (da)	1984-01-11
EP0122219A2 (de)	1984-10-17
BE898649A (fr)	1984-07-11
EP0122219B1 (de)	1988-09-21
GB2134529A (en)	1984-08-15
MC1564A1 (fr)	1984-11-12
GB8400251D0 (en)	1984-02-08
GB2134529B (en)	1986-09-24
HU190750B (en)	1986-10-28
IE56545B1 (en)	1991-08-28
AT391467B (de)	1990-10-10
ES528770A0 (es)	1985-05-01
FI82682B (fi)	1990-12-31
IL70660A (en)	1987-08-31
PH21795A (en)	1988-02-29
MTP943B (en)	1984-06-05
EG16562A (en)	1991-12-30
NO162862B (no)	1989-11-20
PT77932B (en)	1986-07-22
ES8504849A1 (es)	1985-05-01
MA20000A1 (fr)	1984-10-01
CS269954B2 (en)	1990-05-14
IL70660A0 (en)	1984-04-30
DE3400491A1 (de)	1984-07-12
DK166683B1 (da)	1993-06-28
DZ593A1 (fr)	2004-09-13
ZW484A1 (en)	1984-08-08
ATE37378T1 (de)	1988-10-15
CS17884A2 (en)	1989-10-13
PL142737B1 (en)	1987-11-30
FI82682C (fi)	1991-04-10
SE8400098D0 (sv)	1984-01-10
FI840069A0 (fi)	1984-01-09
PL245656A1 (en)	1985-01-02
HUT34151A (en)	1985-02-28
FI840069A (fi)	1984-07-13
NO840090L (no)	1984-07-13
JPS59134759A (ja)	1984-08-02
FR2542735B1 (fr)	1986-04-18
HK90390A (en)	1990-11-09
AU570230B2 (en)	1988-03-10
LU85171A1 (de)	1984-10-24
SE457959B (sv)	1989-02-13
NO162862C (no)	1990-02-28
KR900006747B1 (ko)	1990-09-20
DD218373A5 (de)	1985-02-06
RO88481A (ro)	1986-01-30
ZA84212B (en)	1984-08-29
DE3400491C2 (it)	1988-11-10
GR79793B (it)	1984-10-31
PT77932A (en)	1984-02-01
SE8400098L (sv)	1984-07-13
CA1218077A (en)	1987-02-17
US4510128A (en)	1985-04-09
IT8447527A0 (it)	1984-01-10
DK11884A (da)	1984-07-13
NL8400098A (nl)	1984-08-01
OA07628A (fr)	1985-05-23
JPH0257058B2 (it)	1990-12-03
DE3474152D1 (en)	1988-10-27
NZ206815A (en)	1986-08-08
CH655507B (it)	1986-04-30
IE840049L (en)	1984-07-12
EP0122219A3 (en)	1985-05-08
AR240310A1 (es)	1990-03-30
KR840007562A (ko)	1984-12-08
ATA784A (de)	1990-04-15

Publication	Publication Date	Title
IT1177501B (it)	1987-08-26	Resinato di un acido carbossilico sosituito, procedimento per la sua preparazione, suo impiego e preparati farmaceutici che contengono questo
IT1153315B (it)	1987-01-14	Preparazioni di insulina stabilizzate e un procedimento per la loro preparazione
DK257485D0 (da)	1985-06-07	Farmaceutiske praeparater til oral indgift
NL190581B (nl)	1993-12-01	7beta-(d-2-amino-2-fenylaceetamido)-3-(propenyl)-3-cefem-4-carbonzuur verbinding en farmaceutisch preparaat dat deze verbinding omvat.
IT8719165A0 (it)	1987-01-26	Derivato di acido tiazolidin-4-carbossilico, sua preparazione e composizioni farmaceutiche che lo contengono.
IT1150499B (it)	1986-12-10	Acidi ossazafosforin-4-tio-alcansolfonici,loro sali neutri,procedimento per la loro preparazione e preparati farmaceutici che li contengono
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