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IS1947B - Setin bensýlamínópíperidín efnasambönd og lyfjablöndur þeirra - Google Patents

Setin bensýlamínópíperidín efnasambönd og lyfjablöndur þeirra

Info

Publication number
IS1947B
IS1947B IS4644A IS4644A IS1947B IS 1947 B IS1947 B IS 1947B IS 4644 A IS4644 A IS 4644A IS 4644 A IS4644 A IS 4644A IS 1947 B IS1947 B IS 1947B
Authority
IS
Iceland
Prior art keywords
pharmaceutical compositions
substituted
compounds
substituted benzylaminopiperidine
benzylaminopiperidine compounds
Prior art date
Application number
IS4644A
Other languages
English (en)
Other versions
IS4644A (is
Inventor
Satake Kunio
Shishido Yuji
Wakabayashi Hiroaki
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of IS4644A publication Critical patent/IS4644A/is
Publication of IS1947B publication Critical patent/IS1947B/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IS4644A 1995-08-24 1997-12-30 Setin bensýlamínópíperidín efnasambönd og lyfjablöndur þeirra IS1947B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24
PCT/IB1996/000572 WO1997008144A1 (en) 1995-08-24 1996-06-10 Substituted benzylaminopiperidine compounds

Publications (2)

Publication Number Publication Date
IS4644A IS4644A (is) 1997-12-30
IS1947B true IS1947B (is) 2004-10-13

Family

ID=11004362

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4644A IS1947B (is) 1995-08-24 1997-12-30 Setin bensýlamínópíperidín efnasambönd og lyfjablöndur þeirra

Country Status (42)

Country Link
US (1) US6506775B1 (is)
EP (2) EP1114817B1 (is)
JP (1) JP3084069B2 (is)
KR (1) KR100288673B1 (is)
CN (1) CN1153764C (is)
AP (1) AP643A (is)
AR (1) AR006305A1 (is)
AT (2) ATE258166T1 (is)
AU (1) AU702698B2 (is)
BG (1) BG64126B1 (is)
BR (1) BR9609989A (is)
CA (1) CA2227814C (is)
CO (1) CO4480738A1 (is)
CZ (1) CZ297543B6 (is)
DE (2) DE69631390T2 (is)
DK (2) DK0861235T3 (is)
DZ (1) DZ2086A1 (is)
ES (2) ES2211684T3 (is)
HK (1) HK1014935A1 (is)
HR (1) HRP960386B1 (is)
HU (1) HU225480B1 (is)
IL (1) IL119078A (is)
IS (1) IS1947B (is)
MA (1) MA23961A1 (is)
MX (1) MX9801467A (is)
MY (1) MY114800A (is)
NO (1) NO310720B1 (is)
NZ (1) NZ308207A (is)
OA (1) OA10666A (is)
PE (2) PE20010700A1 (is)
PL (1) PL186773B1 (is)
PT (2) PT861235E (is)
RO (1) RO119299B1 (is)
RU (1) RU2152930C2 (is)
SI (2) SI0861235T1 (is)
SK (1) SK282925B6 (is)
TN (1) TNSN96107A1 (is)
TR (1) TR199800300T1 (is)
TW (1) TW340842B (is)
UA (1) UA48981C2 (is)
WO (1) WO1997008144A1 (is)
YU (1) YU49122B (is)

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MX9706196A (es) * 1996-08-14 1998-02-28 Pfizer Compuestos triciclicos de piperidinilamino como antagonistas de la sustancia p.
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
US6777428B1 (en) 1999-02-10 2004-08-17 Eli Lilly And Company 5-HT1f agonist
EE200100586A (et) * 1999-05-06 2003-02-17 Pfizer Products Inc. Asendatud bensolaktaamühendid
RS49964B (sr) 1999-05-17 2008-09-29 Pfizer Products Inc., Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
AU775861B2 (en) 1999-05-21 2004-08-19 Pfizer Products Inc. 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives
JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のnk−1レセプターアンタゴニスト及びエレトリプタン
US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (en) * 2000-09-28 2003-03-26 Pfizer Products Inc. Combination, for treating depression and anxiety, containing an NK-3 receptor antagonist and a CNS penetrant NK-1 receptor antagonist
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
CN1777584A (zh) 2003-04-18 2006-05-24 伊莱利利公司 作为5-ht1f激动剂的(哌啶氧基)苯基、(哌啶氧基)吡啶基、(哌啶硫基)苯基和(哌啶硫基)吡啶基化合物
CA2566920A1 (en) * 2004-05-21 2005-12-01 Pfizer Products Inc. Metabolites of (+)-(2s, 3s)-3-(2-methoxy-5-trifluoromethoxybenzylamino)-2-phenyl-piperidine
MX2007000428A (es) 2004-07-15 2008-03-05 Amr Technology Inc Tetrahidroisoquinolinas sustituidas con arilo y heteroarilo y uso de las mismas para bloquear la captacion de norepinefrina, dopamina y serotonina.
ES2382814T3 (es) 2005-05-17 2012-06-13 Merck Sharp & Dohme Ltd. Ácido cis-4-[(4-clorofenil)sulfonil]-4-(2,5-difluorofenil)ciclohexanopropanoico para el tratamiento del cáncer
UA95454C2 (uk) 2005-07-15 2011-08-10 Амр Текнолоджи, Інк. Арил- і гетероарилзаміщені тетрагідробензазепіни і їх застосування для блокування зворотного захоплення норепінефрину, допаміну і серотоніну
EP1940842B1 (en) 2005-09-29 2012-05-30 Merck Sharp & Dohme Corp. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
EP2083831B1 (en) 2006-09-22 2013-12-25 Merck Sharp & Dohme Corp. Method of treatment using fatty acid synthesis inhibitors
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
AU2008204380B2 (en) 2007-01-10 2013-08-15 Msd Italia S.R.L. Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
AU2008233662B2 (en) 2007-04-02 2012-08-23 Msd K.K. Indoledione derivative
JP5501227B2 (ja) 2007-06-27 2014-05-21 メルク・シャープ・アンド・ドーム・コーポレーション ヒストンデアセチラーゼ阻害剤としての4−カルボキシベンジルアミノ誘導体
JP2011515343A (ja) 2008-03-03 2011-05-19 タイガー ファーマテック チロシンキナーゼ阻害薬
EP2264029A4 (en) 2008-03-31 2011-08-24 Kowa Co 1,3-dihydroisobenzofuran DERIVATIVE
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
MX2011011901A (es) 2009-05-12 2012-01-20 Albany Molecular Res Inc Tetrahidroisoquinolinas aril, heteroaril, y heterociclo sustituidas y uso de las mismas.
KR20120023072A (ko) 2009-05-12 2012-03-12 브리스톨-마이어스 스큅 컴퍼니 (S)-7-(〔1,2,4〕트리아졸〔1,5-a〕피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린의 결정형 및 이의 용도
MX2011011907A (es) 2009-05-12 2012-01-20 Albany Molecular Res Inc 7-([1,2,4,]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2, 3,4-tetrahidroisoquinolina y uso de la misma.
MY174452A (en) 2009-10-14 2020-04-19 Schering Corp Substituted piperidines that increase p53 activity and the uses thereof
US8999957B2 (en) 2010-06-24 2015-04-07 Merck Sharp & Dohme Corp. Heterocyclic compounds as ERK inhibitors
WO2012018754A2 (en) 2010-08-02 2012-02-09 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
AU2011292261B2 (en) 2010-08-17 2015-05-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of Hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA)
US8883801B2 (en) 2010-08-23 2014-11-11 Merck Sharp & Dohme Corp. Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
EP2613782B1 (en) 2010-09-01 2016-11-02 Merck Sharp & Dohme Corp. Indazole derivatives useful as erk inhibitors
WO2012036997A1 (en) 2010-09-16 2012-03-22 Schering Corporation Fused pyrazole derivatives as novel erk inhibitors
DK2632472T3 (en) 2010-10-29 2018-03-19 Sirna Therapeutics Inc RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
US9351965B2 (en) 2010-12-21 2016-05-31 Merck Sharp & Dohme Corp. Indazole derivatives useful as ERK inhibitors
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AU2013323508B2 (en) 2012-09-28 2017-11-02 Merck Sharp & Dohme Corp. Novel compounds that are ERK inhibitors
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
AU2013352568B2 (en) 2012-11-28 2019-09-19 Merck Sharp & Dohme Llc Compositions and methods for treating cancer
US8846657B2 (en) 2012-12-20 2014-09-30 Merck Sharp & Dohme Corp. Substituted imidazopyridines as HDM2 inhibitors
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US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
CZ289960B6 (cs) * 1991-03-26 2002-05-15 Pfizer Inc. Způsob přípravy substituovaných piperidinů
ES2092113T3 (es) * 1991-06-20 1996-11-16 Pfizer Derivados fluoroalcoxibencilamino de heterociclos que contienen nitrogeno.
US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
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Also Published As

Publication number Publication date
US6506775B1 (en) 2003-01-14
DK1114817T3 (da) 2004-04-26
HRP960386A2 (en) 1998-04-30
AU702698B2 (en) 1999-03-04
PL186773B1 (pl) 2004-02-27
EP1114817B1 (en) 2004-01-21
DZ2086A1 (fr) 2002-07-22
SK282925B6 (sk) 2003-01-09
PL325332A1 (en) 1998-07-20
OA10666A (en) 2002-11-25
TR199800300T1 (xx) 1998-06-22
PT1114817E (pt) 2004-05-31
CO4480738A1 (es) 1997-07-09
DE69616817D1 (de) 2001-12-13
SK20798A3 (en) 1999-03-12
KR100288673B1 (ko) 2001-05-02
ATE208377T1 (de) 2001-11-15
HUP9901159A3 (en) 2000-05-29
MA23961A1 (fr) 1997-04-01
JPH10510554A (ja) 1998-10-13
MY114800A (en) 2003-01-31
NO980751L (no) 1998-02-23
HRP960386B1 (en) 2002-04-30
NO980751D0 (no) 1998-02-23
RO119299B1 (ro) 2004-07-30
CZ297543B6 (cs) 2007-02-07
JP3084069B2 (ja) 2000-09-04
EP1114817A1 (en) 2001-07-11
YU49122B (sh) 2004-03-12
ES2163017T3 (es) 2002-01-16
IS4644A (is) 1997-12-30
HU225480B1 (en) 2006-12-28
MX9801467A (es) 1998-05-31
IL119078A0 (en) 1996-11-14
HK1014935A1 (en) 1999-10-08
DE69631390D1 (de) 2004-02-26
EP0861235A1 (en) 1998-09-02
WO1997008144A1 (en) 1997-03-06
DE69616817T2 (de) 2002-04-04
HUP9901159A2 (hu) 1999-07-28
AR006305A1 (es) 1999-08-25
CA2227814C (en) 2002-12-31
NO310720B1 (no) 2001-08-20
DE69631390T2 (de) 2004-11-25
BR9609989A (pt) 1999-07-06
ATE258166T1 (de) 2004-02-15
BG64126B1 (bg) 2004-01-30
CA2227814A1 (en) 1997-03-06
KR19990044077A (ko) 1999-06-25
SI1114817T1 (en) 2004-06-30
RU2152930C2 (ru) 2000-07-20
PT861235E (pt) 2002-03-28
CZ52198A3 (cs) 1999-01-13
NZ308207A (en) 1998-07-28
AP643A (en) 1998-04-24
EP0861235B1 (en) 2001-11-07
TNSN96107A1 (fr) 2005-03-15
PE20010700A1 (es) 2001-07-09
AP9600850A0 (en) 1996-10-31
SI0861235T1 (en) 2002-04-30
CN1153764C (zh) 2004-06-16
BG102288A (en) 1998-09-30
DK0861235T3 (da) 2001-12-27
CN1193961A (zh) 1998-09-23
UA48981C2 (uk) 2002-09-16
PE1398A1 (es) 1998-02-27
AU5776996A (en) 1997-03-19
TW340842B (en) 1998-09-21
YU47896A (sh) 1998-12-23
ES2211684T3 (es) 2004-07-16
IL119078A (en) 2003-11-23

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