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ATE208377T1 - Substituierte benzylaminopiperloin verbindungen - Google Patents

Substituierte benzylaminopiperloin verbindungen

Info

Publication number
ATE208377T1
ATE208377T1 AT96914375T AT96914375T ATE208377T1 AT E208377 T1 ATE208377 T1 AT E208377T1 AT 96914375 T AT96914375 T AT 96914375T AT 96914375 T AT96914375 T AT 96914375T AT E208377 T1 ATE208377 T1 AT E208377T1
Authority
AT
Austria
Prior art keywords
benzylaminopiperloin
substituted
compounds
substituted benzylaminopiperloin
benzylaminopiperloin compounds
Prior art date
Application number
AT96914375T
Other languages
English (en)
Inventor
Kunio Satake
Yuji Shishido
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE208377T1 publication Critical patent/ATE208377T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96914375T 1995-08-24 1996-06-10 Substituierte benzylaminopiperloin verbindungen ATE208377T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24
PCT/IB1996/000572 WO1997008144A1 (en) 1995-08-24 1996-06-10 Substituted benzylaminopiperidine compounds

Publications (1)

Publication Number Publication Date
ATE208377T1 true ATE208377T1 (de) 2001-11-15

Family

ID=11004362

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01108350T ATE258166T1 (de) 1995-08-24 1996-06-10 Substituierte benzylaminpiperidin-verbindungen
AT96914375T ATE208377T1 (de) 1995-08-24 1996-06-10 Substituierte benzylaminopiperloin verbindungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01108350T ATE258166T1 (de) 1995-08-24 1996-06-10 Substituierte benzylaminpiperidin-verbindungen

Country Status (41)

Country Link
US (1) US6506775B1 (de)
EP (2) EP1114817B1 (de)
JP (1) JP3084069B2 (de)
KR (1) KR100288673B1 (de)
CN (1) CN1153764C (de)
AP (1) AP643A (de)
AR (1) AR006305A1 (de)
AT (2) ATE258166T1 (de)
AU (1) AU702698B2 (de)
BG (1) BG64126B1 (de)
BR (1) BR9609989A (de)
CA (1) CA2227814C (de)
CO (1) CO4480738A1 (de)
CZ (1) CZ297543B6 (de)
DE (2) DE69631390T2 (de)
DK (2) DK0861235T3 (de)
DZ (1) DZ2086A1 (de)
ES (2) ES2163017T3 (de)
HR (1) HRP960386B1 (de)
HU (1) HU225480B1 (de)
IL (1) IL119078A (de)
IS (1) IS1947B (de)
MA (1) MA23961A1 (de)
MX (1) MX9801467A (de)
MY (1) MY114800A (de)
NO (1) NO310720B1 (de)
NZ (1) NZ308207A (de)
OA (1) OA10666A (de)
PE (2) PE1398A1 (de)
PL (1) PL186773B1 (de)
PT (2) PT861235E (de)
RO (1) RO119299B1 (de)
RU (1) RU2152930C2 (de)
SI (2) SI0861235T1 (de)
SK (1) SK282925B6 (de)
TN (1) TNSN96107A1 (de)
TR (1) TR199800300T1 (de)
TW (1) TW340842B (de)
UA (1) UA48981C2 (de)
WO (1) WO1997008144A1 (de)
YU (1) YU49122B (de)

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EE04719B1 (et) * 1999-05-21 2006-10-16 Pfizer Products Inc. 1-trifluorometüül-4-hüdroksü-7-piperidinüül-aminometüülkromaani derivaadid
DE60007599T2 (de) * 1999-10-18 2004-11-11 Pfizer Products Inc., Groton Verfahren zur Herstellung von zyklischen Piperidinylaminomethyl-trifluoromethyl-etherderivaten
JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のｎｋ−１レセプターアンタゴニスト及びエレトリプタン
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
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EP1192952A3 (de) * 2000-09-28 2003-03-26 Pfizer Products Inc. Ein NK-3 rezeptorantagonisten und ein ZNS-penetrierende NK-1 rezeptorantagonisten enthaltende Zusammensetzung zur Behandlung von Depression und Angst
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
BRPI0409211A (pt) 2003-04-18 2006-03-28 Lilly Co Eli composto, composição farmacêutica, métodos para ativar receptores 5-ht1f, para inibir extravasão de proteìna neuronial, e para o tratamento ou prevenção de enxaqueca em um mamìfero, e, uso de um composto
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US8362075B2 (en) 2005-05-17 2013-01-29 Merck Sharp & Dohme Corp. Cyclohexyl sulphones for treatment of cancer
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JP5489333B2 (ja) 2006-09-22 2014-05-14 メルク・シャープ・アンド・ドーム・コーポレーション 脂肪酸合成阻害剤を用いた治療の方法
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
CA2674436C (en) 2007-01-10 2012-07-17 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
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AU2009222122A1 (en) 2008-03-03 2009-09-11 Tiger Pharmatech Tyrosine kinase inhibitors
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US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
ES2446971T3 (es) 2009-05-12 2014-03-11 Albany Molecular Research, Inc. Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso
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Also Published As

Publication number Publication date
DE69631390D1 (de) 2004-02-26
TNSN96107A1 (fr) 2005-03-15
PT1114817E (pt) 2004-05-31
PE20010700A1 (es) 2001-07-09
RO119299B1 (ro) 2004-07-30
TR199800300T1 (xx) 1998-06-22
SI0861235T1 (en) 2002-04-30
ES2211684T3 (es) 2004-07-16
IS1947B (is) 2004-10-13
JPH10510554A (ja) 1998-10-13
MA23961A1 (fr) 1997-04-01
PE1398A1 (es) 1998-02-27
AU702698B2 (en) 1999-03-04
EP0861235B1 (de) 2001-11-07
OA10666A (en) 2002-11-25
NO310720B1 (no) 2001-08-20
BG102288A (en) 1998-09-30
AU5776996A (en) 1997-03-19
NO980751L (no) 1998-02-23
US6506775B1 (en) 2003-01-14
IL119078A0 (en) 1996-11-14
MX9801467A (es) 1998-05-31
HUP9901159A3 (en) 2000-05-29
DK0861235T3 (da) 2001-12-27
DE69616817D1 (de) 2001-12-13
EP1114817A1 (de) 2001-07-11
ATE258166T1 (de) 2004-02-15
IL119078A (en) 2003-11-23
PT861235E (pt) 2002-03-28
HRP960386B1 (en) 2002-04-30
KR19990044077A (ko) 1999-06-25
EP1114817B1 (de) 2004-01-21
CO4480738A1 (es) 1997-07-09
EP0861235A1 (de) 1998-09-02
PL325332A1 (en) 1998-07-20
HRP960386A2 (en) 1998-04-30
CN1153764C (zh) 2004-06-16
DE69631390T2 (de) 2004-11-25
CA2227814C (en) 2002-12-31
HU225480B1 (en) 2006-12-28
DK1114817T3 (da) 2004-04-26
CN1193961A (zh) 1998-09-23
HK1014935A1 (en) 1999-10-08
AR006305A1 (es) 1999-08-25
YU47896A (sh) 1998-12-23
JP3084069B2 (ja) 2000-09-04
SI1114817T1 (en) 2004-06-30
AP643A (en) 1998-04-24
IS4644A (is) 1997-12-30
NZ308207A (en) 1998-07-28
RU2152930C2 (ru) 2000-07-20
CZ52198A3 (cs) 1999-01-13
SK282925B6 (sk) 2003-01-09
MY114800A (en) 2003-01-31
BG64126B1 (bg) 2004-01-30
NO980751D0 (no) 1998-02-23
UA48981C2 (uk) 2002-09-16
CZ297543B6 (cs) 2007-02-07
KR100288673B1 (ko) 2001-05-02
PL186773B1 (pl) 2004-02-27
ES2163017T3 (es) 2002-01-16
SK20798A3 (en) 1999-03-12
YU49122B (sh) 2004-03-12
WO1997008144A1 (en) 1997-03-06
HUP9901159A2 (hu) 1999-07-28
AP9600850A0 (en) 1996-10-31
BR9609989A (pt) 1999-07-06
DE69616817T2 (de) 2002-04-04
TW340842B (en) 1998-09-21
DZ2086A1 (fr) 2002-07-22
CA2227814A1 (en) 1997-03-06

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