IL90533A - History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing them - Google Patents
History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL90533A IL90533A IL9053389A IL9053389A IL90533A IL 90533 A IL90533 A IL 90533A IL 9053389 A IL9053389 A IL 9053389A IL 9053389 A IL9053389 A IL 9053389A IL 90533 A IL90533 A IL 90533A
- Authority
- IL
- Israel
- Prior art keywords
- bridge
- benzazepines
- hydroxy
- hydrogen
- benzazepine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK325188A DK325188D0 (da) | 1988-06-15 | 1988-06-15 | Hidtil ukendte benzazepinderivater |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL90533A0 IL90533A0 (en) | 1990-01-18 |
| IL90533A true IL90533A (en) | 1994-05-30 |
Family
ID=8120790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9053389A IL90533A (en) | 1988-06-15 | 1989-06-05 | History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5010074A (no) |
| EP (1) | EP0347672B1 (no) |
| JP (1) | JP2769718B2 (no) |
| AT (1) | ATE102188T1 (no) |
| AU (1) | AU622911B2 (no) |
| CA (1) | CA1317938C (no) |
| DE (1) | DE68913367T2 (no) |
| DK (1) | DK325188D0 (no) |
| ES (1) | ES2061794T3 (no) |
| FI (1) | FI93354C (no) |
| IE (1) | IE891932L (no) |
| IL (1) | IL90533A (no) |
| NO (1) | NO173865C (no) |
| NZ (1) | NZ229521A (no) |
| PT (1) | PT90883B (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK67489D0 (da) * | 1989-02-14 | 1989-02-14 | Novo Industri As | Nye benzazepinderivater |
| US5158948A (en) * | 1990-11-16 | 1992-10-27 | Abbott Laboratories | Tetracyclic spirobenzazepine dopamine antagonists |
| US5470850A (en) * | 1992-02-24 | 1995-11-28 | Novo Nordisk A/S | 2,3,4,5-tetrahydro-1H-3-benzazepines |
| DK23392D0 (da) * | 1992-02-24 | 1992-02-24 | Novo Nordisk As | Heterocykliske forbindelser, deres anvendelse og fremstilling |
| PL189822B1 (pl) * | 1997-03-12 | 2005-09-30 | Addex Pharmaceuticals Sa | Zastosowanie (+)-5-(2,3-dihydrobenzofuran-7-ylo)-7-hydroksy-3-metylo-8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepiny lub jej farmaceutycznie dopuszczalnej soli do wytwarzania kompozycji farmaceutycznej |
| US6277844B1 (en) | 1998-09-14 | 2001-08-21 | Sydney Spector | Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis |
| GB0130576D0 (en) * | 2001-12-20 | 2002-02-06 | Cenes Ltd | Dopamine D1 receptor agonist pro-drug compounds & derivatives |
| CN1688584A (zh) * | 2002-08-29 | 2005-10-26 | 先灵公司 | 治疗肥胖和中枢神经系统疾病的选择性d1/d5受体拮抗剂 |
| AU2003294909B2 (en) | 2002-12-20 | 2007-05-17 | Glaxo Group Limited | Benzazepine derivatives for the treatment of neurological disorders |
| JP2006526021A (ja) * | 2003-05-22 | 2006-11-16 | シェーリング コーポレイション | 肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA974989A (en) * | 1968-03-11 | 1975-09-23 | Wallace And Tiernan Inc. | Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby |
| US4210749A (en) * | 1974-11-12 | 1980-07-01 | Pennwalt Corporation | Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines |
| ZA792044B (en) * | 1978-05-08 | 1980-05-28 | Scherico Ltd | Substituted 1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof,and pharmaceutical compositions containing them |
| US4327023A (en) * | 1980-01-31 | 1982-04-27 | Smithkline Corporation | Intermediates for preparing 7,8-amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US4284556A (en) * | 1980-01-31 | 1981-08-18 | Smithkline Corporation | 7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
| DK180485D0 (da) * | 1985-04-22 | 1985-04-23 | Novo Industri As | Nitrogenholdige forbindelser |
| WO1987004430A2 (en) * | 1986-01-16 | 1987-07-30 | Schering Corporation | Fused benzazepines |
| EP0244088A3 (en) * | 1986-04-03 | 1989-03-15 | Smithkline Beecham Corporation | 1-phenyl-3-benzazepine compounds and medicaments containing these compounds for treating gastrointestinal motility disorders |
-
1988
- 1988-06-15 DK DK325188A patent/DK325188D0/da not_active Application Discontinuation
-
1989
- 1989-06-05 IL IL9053389A patent/IL90533A/en unknown
- 1989-06-09 ES ES89110490T patent/ES2061794T3/es not_active Expired - Lifetime
- 1989-06-09 EP EP89110490A patent/EP0347672B1/en not_active Expired - Lifetime
- 1989-06-09 AT AT89110490T patent/ATE102188T1/de not_active IP Right Cessation
- 1989-06-09 DE DE68913367T patent/DE68913367T2/de not_active Expired - Lifetime
- 1989-06-12 US US07/365,250 patent/US5010074A/en not_active Expired - Lifetime
- 1989-06-13 CA CA000602684A patent/CA1317938C/en not_active Expired - Lifetime
- 1989-06-13 NZ NZ229521A patent/NZ229521A/en unknown
- 1989-06-14 NO NO892476A patent/NO173865C/no not_active IP Right Cessation
- 1989-06-14 AU AU36359/89A patent/AU622911B2/en not_active Expired
- 1989-06-15 JP JP1150662A patent/JP2769718B2/ja not_active Expired - Lifetime
- 1989-06-15 PT PT90883A patent/PT90883B/pt not_active IP Right Cessation
- 1989-06-15 IE IE891932A patent/IE891932L/xx not_active IP Right Cessation
- 1989-06-15 FI FI892946A patent/FI93354C/fi active IP Right Grant
-
1990
- 1990-02-07 US US07/477,450 patent/US5025009A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2061794T3 (es) | 1994-12-16 |
| NZ229521A (en) | 1991-12-23 |
| IL90533A0 (en) | 1990-01-18 |
| PT90883B (pt) | 1994-12-30 |
| NO173865C (no) | 1994-02-16 |
| IE891932L (en) | 1989-12-15 |
| PT90883A (pt) | 1989-12-29 |
| EP0347672B1 (en) | 1994-03-02 |
| NO173865B (no) | 1993-11-08 |
| EP0347672A1 (en) | 1989-12-27 |
| FI892946A (fi) | 1989-12-16 |
| JPH0240364A (ja) | 1990-02-09 |
| CA1317938C (en) | 1993-05-18 |
| NO892476D0 (no) | 1989-06-14 |
| FI93354C (fi) | 1995-03-27 |
| FI892946A0 (fi) | 1989-06-15 |
| US5010074A (en) | 1991-04-23 |
| DE68913367T2 (de) | 1994-06-01 |
| JP2769718B2 (ja) | 1998-06-25 |
| DK325188D0 (da) | 1988-06-15 |
| DE68913367D1 (de) | 1994-04-07 |
| US5025009A (en) | 1991-06-18 |
| FI93354B (fi) | 1994-12-15 |
| AU3635989A (en) | 1989-12-21 |
| AU622911B2 (en) | 1992-04-30 |
| NO892476L (no) | 1989-12-18 |
| ATE102188T1 (de) | 1994-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed |