IL42728A - (1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indole)-acetoxy-acetic acid,its preparation and pharmaceutical compositions containing it - Google Patents

(1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indole)-acetoxy-acetic acid,its preparation and pharmaceutical compositions containing it

Info

Publication number: IL42728A
Authority: IL; Israel
Prior art keywords: indole; acetoxy; chlorobenzoyl; methoxy; methyl
Prior art date: 1972-07-14

Application number

IL42728A

Other languages

English (en)

Other versions

IL42728A0 (en

Original Assignee

Troponwerke Dinklage & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-07-14

Filing date

1973-07-12

Publication date

1976-05-31

1973-07-12 Application filed by Troponwerke Dinklage & Co filed Critical Troponwerke Dinklage & Co

1973-10-25 Publication of IL42728A0 publication Critical patent/IL42728A0/xx

1976-05-31 Publication of IL42728A publication Critical patent/IL42728A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL42728A 1972-07-14 1973-07-12 (1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indole)-acetoxy-acetic acid,its preparation and pharmaceutical compositions containing it IL42728A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2234651A DE2234651C3 (de)	1972-07-14	1972-07-14	Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen

Publications (2)

Publication Number	Publication Date
IL42728A0 IL42728A0 (en)	1973-10-25
IL42728A true IL42728A (en)	1976-05-31

Family

ID=5850654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL42728A IL42728A (en)	1972-07-14	1973-07-12	(1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indole)-acetoxy-acetic acid,its preparation and pharmaceutical compositions containing it

Country Status (27)

Country	Link
US (1)	US3910952A (fi)
JP (1)	JPS5147708B2 (fi)
AR (1)	AR197345A1 (fi)
AT (1)	AT324322B (fi)
AU (1)	AU473000B2 (fi)
BE (1)	BE802358A (fi)
CA (1)	CA979893A (fi)
CH (1)	CH582141A5 (fi)
CS (1)	CS179418B2 (fi)
DD (1)	DD107917A5 (fi)
DE (1)	DE2234651C3 (fi)
DK (1)	DK134400C (fi)
ES (1)	ES416877A1 (fi)
FI (1)	FI56833C (fi)
FR (1)	FR2192828B1 (fi)
GB (1)	GB1411350A (fi)
HU (1)	HU165158B (fi)
IE (1)	IE38039B1 (fi)
IL (1)	IL42728A (fi)
NL (1)	NL173748C (fi)
OA (1)	OA04546A (fi)
PL (1)	PL91610B1 (fi)
RO (1)	RO64477A (fi)
SE (1)	SE380522B (fi)
SU (1)	SU474980A3 (fi)
YU (1)	YU35353B (fi)
ZA (1)	ZA734735B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1531546A (en) *	1976-05-19	1978-11-08	Pierrel Spa	Anti-inflammatory indole derivative
JPS52156862A (en) *	1976-06-22	1977-12-27	Hisamitsu Pharmaceut Co Inc	Novel indoleacetic acid ester derivatives
CS190723B1 (en) *	1976-06-30	1979-06-29	Ludmila Fisnerova	2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same
GB1587070A (en) *	1977-06-02	1981-03-25	Sterwin Ag	Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them
DE2735537A1 (de) *	1977-08-06	1979-02-22	Troponwerke Gmbh & Co Kg	Indolacetoxyacetylaminosaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2943125A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure
DE2943127A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	(1-(4-chlorbenzoyl)-methoxy-2-methyl-3-indol) -acetoxyessigsaeuremonohydrat, verfahren zur herstellung sowie dessen verwendung in arzneimitteln
DE2943126A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	Laevulinoyloxyessigsaeure und verfahren zu ihrer herstellung
FR2499076A1 (fr) *	1981-02-02	1982-08-06	Panmedica Laboratoires	Nouveaux derives de l'acide ((indol-3 yl)-3 amino-2 propionyloxy)-2 acetique, procedes pour leur preparation et medicaments les contenant
CH653326A5 (de) *	1981-12-28	1985-12-31	Siegfried Ag	Verfahren zur herstellung eines indolderivates.
DE3206886A1 (de) *	1982-02-26	1983-10-27	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3- indolacetoxyessigsaeure
DE3206888A1 (de) *	1982-02-26	1983-09-15	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure
JPS59204172A (ja) *	1983-04-28	1984-11-19	Kowa Co	アセメタシンの製造法
JPS60112760A (ja) *	1983-11-18	1985-06-19	Green Cross Corp:The	インド−ル酢酸誘導体及びその脂肪乳剤
WO2006099677A1 (en) *	2005-03-24	2006-09-28	Medical Therapies Limited	Metal complexes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3775429A (en) *	1966-10-13	1973-11-27	Merck & Co Inc	Process for preparing 3-indolyl acetic acids
US3518280A (en) *	1968-06-27	1970-06-30	Merck & Co Inc	1-p-chlorobenzoyl-2-methyl-5-methoxyindole-3-malonic acid derivatives

1972
- 1972-07-14 DE DE2234651A patent/DE2234651C3/de not_active Expired
1973
- 1973-06-28 US US374615A patent/US3910952A/en not_active Expired - Lifetime
- 1973-07-06 CS CS7300004899A patent/CS179418B2/cs unknown
- 1973-07-06 SU SU1942666A patent/SU474980A3/ru active
- 1973-07-09 YU YU1858/73A patent/YU35353B/xx unknown
- 1973-07-11 RO RO7375429A patent/RO64477A/ro unknown
- 1973-07-11 PL PL1973163991A patent/PL91610B1/pl unknown
- 1973-07-12 FI FI2213/73A patent/FI56833C/fi active
- 1973-07-12 CA CA176,315A patent/CA979893A/en not_active Expired
- 1973-07-12 DD DD172231A patent/DD107917A5/xx unknown
- 1973-07-12 IL IL42728A patent/IL42728A/en unknown
- 1973-07-12 HU HUTO961A patent/HU165158B/hu unknown
- 1973-07-12 AU AU58011/73A patent/AU473000B2/en not_active Expired
- 1973-07-12 IE IE1181/73A patent/IE38039B1/xx unknown
- 1973-07-12 ZA ZA734735A patent/ZA734735B/xx unknown
- 1973-07-13 BE BE133498A patent/BE802358A/xx not_active IP Right Cessation
- 1973-07-13 AR AR249094A patent/AR197345A1/es active
- 1973-07-13 GB GB3343573A patent/GB1411350A/en not_active Expired
- 1973-07-13 DK DK389973A patent/DK134400C/da not_active IP Right Cessation
- 1973-07-13 SE SE7309900A patent/SE380522B/xx unknown
- 1973-07-13 FR FR7325791A patent/FR2192828B1/fr not_active Expired
- 1973-07-13 AT AT619473A patent/AT324322B/de not_active IP Right Cessation
- 1973-07-13 CH CH1026673A patent/CH582141A5/xx not_active IP Right Cessation
- 1973-07-13 NL NLAANVRAGE7309811,A patent/NL173748C/xx not_active IP Right Cessation
- 1973-07-13 OA OA54967A patent/OA04546A/xx unknown
- 1973-07-13 ES ES416877A patent/ES416877A1/es not_active Expired
- 1973-07-13 JP JP48079201A patent/JPS5147708B2/ja not_active Expired

Also Published As

Publication number	Publication date
JPS5147708B2 (fi)	1976-12-16
DD107917A5 (fi)	1974-08-20
AR197345A1 (es)	1974-03-29
IE38039B1 (en)	1977-12-07
NL7309811A (fi)	1974-01-16
AU473000B2 (en)	1976-06-10
HU165158B (fi)	1974-06-28
DE2234651B2 (de)	1978-02-23
AT324322B (de)	1975-08-25
FR2192828A1 (fi)	1974-02-15
DE2234651C3 (de)	1978-11-09
SE380522B (sv)	1975-11-10
NL173748C (nl)	1984-03-01
FI56833B (fi)	1979-12-31
FI56833C (fi)	1980-04-10
AU5801173A (en)	1975-01-16
PL91610B1 (fi)	1977-03-31
BE802358A (fr)	1974-01-14
IE38039L (en)	1974-01-14
RO64477A (fr)	1979-08-15
YU35353B (en)	1980-12-31
ZA734735B (en)	1974-06-26
NL173748B (nl)	1983-10-03
OA04546A (fr)	1980-04-30
ES416877A1 (es)	1976-02-16
DE2234651A1 (de)	1974-04-04
DK134400B (da)	1976-11-01
YU185873A (en)	1980-06-30
US3910952A (en)	1975-10-07
IL42728A0 (en)	1973-10-25
CA979893A (en)	1975-12-16
CH582141A5 (fi)	1976-11-30
GB1411350A (en)	1975-10-22
JPS4943970A (fi)	1974-04-25
SU474980A3 (ru)	1975-06-25
DK134400C (da)	1977-03-28
FR2192828B1 (fi)	1976-10-22
CS179418B2 (en)	1977-10-31

Publication	Publication Date	Title
IL42728A (en)	1976-05-31	(1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indole)-acetoxy-acetic acid,its preparation and pharmaceutical compositions containing it
US3725548A (en)	1973-04-03	Substituted indenyl acetic acids in the treatment of pain, fever or inflammation
US3932498A (en)	1976-01-13	3-Indenyl-γ-(ketobutyric)-acid compounds
US3712900A (en)	1973-01-23	Benzyl amino carbamate substituted pyridines
CH542201A (de)	1973-09-30	Verfahren zur Herstellung von Indolinderivaten
US3803176A (en)	1974-04-09	Sulfonylurea derivatives
US3728346A (en)	1973-04-17	Hydroxyphenylhydroxyalkylaminoalkyltheophyllines
IE34314B1 (en)	1975-04-02	Dibenzodioxocine derivatives
US2605285A (en)	1952-07-29	Urea derivatives and their preparation
US3781415A (en)	1973-12-25	Product,process and composition
US3778511A (en)	1973-12-11	Alpha-(1,2,3,4-tetrahydro-6-quinoyl)-carboxylic acids and derivatives thereof for treating inflammation
IL33226A (en)	1973-10-25	Omega-nor and omega-homo pgf2beta derivatives and process for their preparation
US3968219A (en)	1976-07-06	Hydroxy phenylbutazone derivatives and their preparation
IL42384A (en)	1976-12-31	N-benzhydryl-n'-p-hydroxybenzyl-piperazines and processes for their manufacture and pharmaceutical compositions containing them
IL31570A (en)	1972-03-28	Laevorotatory indole derivatives,their production and pharmaceutical compositions containing them
US3725419A (en)	1973-04-03	Quinuclidylalkyl esters
GB1476053A (en)	1977-06-10	Glycyrrhetinic acid derivatives
ES363199A1 (es)	1970-12-01	Procedimiento para la preparacion de benzoxazinas.
US4110376A (en)	1978-08-29	Cyclopropylmethylamine derivatives
US3598862A (en)	1971-08-10	2 - (4 - (3',5' - diphenylcyclohexyl) - phenoxy)lower aliphatic monocarbocylic acids and esters thereof
US3853954A (en)	1974-12-10	Tyrosine derivatives
US3821415A (en)	1974-06-28	Heterocyclic compounds in pharmaceutical compositions and methods
GB1334125A (en)	1973-10-17	Aminopropionanilides and a process for the preparation thereof
US3455999A (en)	1969-07-15	Substituted malonic acid monohydrazides
US3897558A (en)	1975-07-29	Hypolipemiant and vasodilatatory methods of use