FI56833B - Foerfarande foer framstaellning av antiflogistiskt verkande (1-(p-klorbenzoyl)-5-metoxi-2-metyl-3-indol)-acetoxiaettiksyra och dess salter - Google Patents

Foerfarande foer framstaellning av antiflogistiskt verkande (1-(p-klorbenzoyl)-5-metoxi-2-metyl-3-indol)-acetoxiaettiksyra och dess salter

Info

Publication number: FI56833B
Authority: FI; Finland
Prior art keywords: acetoxyethyxide; antiflogistic; chlorbenzoyl; indol; methoxy
Prior art date: 1972-07-14

Application number

FI2213/73A

Other languages

English (en)

Other versions

FI56833C (fi

Inventor

Karl-Heinz Boltze

Otfried Brendler

Hans-Dieter Dell

Haireddin Jacobi

Original Assignee

Troponwerke Dinklage & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-07-14

Filing date

1973-07-12

Publication date

1979-12-31

1973-07-12 Application filed by Troponwerke Dinklage & Co filed Critical Troponwerke Dinklage & Co

1979-12-31 Publication of FI56833B publication Critical patent/FI56833B/fi

1980-04-10 Application granted granted Critical

1980-04-10 Publication of FI56833C publication Critical patent/FI56833C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI2213/73A 1972-07-14 1973-07-12 Foerfarande foer framstaellning av antiflogistiskt verkande (1-(p-klorbenzoyl)-5-metoxi-2-metyl-3-indol)-acetoxiaettiksyra och dess salter FI56833C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2234651A DE2234651C3 (de)	1972-07-14	1972-07-14	Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen
DE2234651		1972-07-14

Publications (2)

Publication Number	Publication Date
FI56833B true FI56833B (fi)	1979-12-31
FI56833C FI56833C (fi)	1980-04-10

Family

ID=5850654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI2213/73A FI56833C (fi)	1972-07-14	1973-07-12	Foerfarande foer framstaellning av antiflogistiskt verkande (1-(p-klorbenzoyl)-5-metoxi-2-metyl-3-indol)-acetoxiaettiksyra och dess salter

Country Status (27)

Country	Link
US (1)	US3910952A (fi)
JP (1)	JPS5147708B2 (fi)
AR (1)	AR197345A1 (fi)
AT (1)	AT324322B (fi)
AU (1)	AU473000B2 (fi)
BE (1)	BE802358A (fi)
CA (1)	CA979893A (fi)
CH (1)	CH582141A5 (fi)
CS (1)	CS179418B2 (fi)
DD (1)	DD107917A5 (fi)
DE (1)	DE2234651C3 (fi)
DK (1)	DK134400C (fi)
ES (1)	ES416877A1 (fi)
FI (1)	FI56833C (fi)
FR (1)	FR2192828B1 (fi)
GB (1)	GB1411350A (fi)
HU (1)	HU165158B (fi)
IE (1)	IE38039B1 (fi)
IL (1)	IL42728A (fi)
NL (1)	NL173748C (fi)
OA (1)	OA04546A (fi)
PL (1)	PL91610B1 (fi)
RO (1)	RO64477A (fi)
SE (1)	SE380522B (fi)
SU (1)	SU474980A3 (fi)
YU (1)	YU35353B (fi)
ZA (1)	ZA734735B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1531546A (en) *	1976-05-19	1978-11-08	Pierrel Spa	Anti-inflammatory indole derivative
JPS52156862A (en) *	1976-06-22	1977-12-27	Hisamitsu Pharmaceut Co Inc	Novel indoleacetic acid ester derivatives
CS190723B1 (en) *	1976-06-30	1979-06-29	Ludmila Fisnerova	2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same
GB1587070A (en) *	1977-06-02	1981-03-25	Sterwin Ag	Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them
DE2735537A1 (de) *	1977-08-06	1979-02-22	Troponwerke Gmbh & Co Kg	Indolacetoxyacetylaminosaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2943125A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure
DE2943127A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	(1-(4-chlorbenzoyl)-methoxy-2-methyl-3-indol) -acetoxyessigsaeuremonohydrat, verfahren zur herstellung sowie dessen verwendung in arzneimitteln
DE2943126A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	Laevulinoyloxyessigsaeure und verfahren zu ihrer herstellung
FR2499076A1 (fr) *	1981-02-02	1982-08-06	Panmedica Laboratoires	Nouveaux derives de l'acide ((indol-3 yl)-3 amino-2 propionyloxy)-2 acetique, procedes pour leur preparation et medicaments les contenant
CH653326A5 (de) *	1981-12-28	1985-12-31	Siegfried Ag	Verfahren zur herstellung eines indolderivates.
DE3206886A1 (de) *	1982-02-26	1983-10-27	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3- indolacetoxyessigsaeure
DE3206888A1 (de) *	1982-02-26	1983-09-15	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure
JPS59204172A (ja) *	1983-04-28	1984-11-19	Kowa Co	アセメタシンの製造法
JPS60112760A (ja) *	1983-11-18	1985-06-19	Green Cross Corp:The	インド−ル酢酸誘導体及びその脂肪乳剤
WO2006099677A1 (en) *	2005-03-24	2006-09-28	Medical Therapies Limited	Metal complexes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3775429A (en) *	1966-10-13	1973-11-27	Merck & Co Inc	Process for preparing 3-indolyl acetic acids
US3518280A (en) *	1968-06-27	1970-06-30	Merck & Co Inc	1-p-chlorobenzoyl-2-methyl-5-methoxyindole-3-malonic acid derivatives

1972
- 1972-07-14 DE DE2234651A patent/DE2234651C3/de not_active Expired
1973
- 1973-06-28 US US374615A patent/US3910952A/en not_active Expired - Lifetime
- 1973-07-06 CS CS7300004899A patent/CS179418B2/cs unknown
- 1973-07-06 SU SU1942666A patent/SU474980A3/ru active
- 1973-07-09 YU YU1858/73A patent/YU35353B/xx unknown
- 1973-07-11 RO RO7375429A patent/RO64477A/ro unknown
- 1973-07-11 PL PL1973163991A patent/PL91610B1/pl unknown
- 1973-07-12 FI FI2213/73A patent/FI56833C/fi active
- 1973-07-12 CA CA176,315A patent/CA979893A/en not_active Expired
- 1973-07-12 DD DD172231A patent/DD107917A5/xx unknown
- 1973-07-12 IL IL42728A patent/IL42728A/en unknown
- 1973-07-12 HU HUTO961A patent/HU165158B/hu unknown
- 1973-07-12 AU AU58011/73A patent/AU473000B2/en not_active Expired
- 1973-07-12 IE IE1181/73A patent/IE38039B1/xx unknown
- 1973-07-12 ZA ZA734735A patent/ZA734735B/xx unknown
- 1973-07-13 BE BE133498A patent/BE802358A/xx not_active IP Right Cessation
- 1973-07-13 AR AR249094A patent/AR197345A1/es active
- 1973-07-13 GB GB3343573A patent/GB1411350A/en not_active Expired
- 1973-07-13 DK DK389973A patent/DK134400C/da not_active IP Right Cessation
- 1973-07-13 SE SE7309900A patent/SE380522B/xx unknown
- 1973-07-13 FR FR7325791A patent/FR2192828B1/fr not_active Expired
- 1973-07-13 AT AT619473A patent/AT324322B/de not_active IP Right Cessation
- 1973-07-13 CH CH1026673A patent/CH582141A5/xx not_active IP Right Cessation
- 1973-07-13 NL NLAANVRAGE7309811,A patent/NL173748C/xx not_active IP Right Cessation
- 1973-07-13 OA OA54967A patent/OA04546A/xx unknown
- 1973-07-13 ES ES416877A patent/ES416877A1/es not_active Expired
- 1973-07-13 JP JP48079201A patent/JPS5147708B2/ja not_active Expired

Also Published As

Publication number	Publication date
JPS5147708B2 (fi)	1976-12-16
DD107917A5 (fi)	1974-08-20
AR197345A1 (es)	1974-03-29
IE38039B1 (en)	1977-12-07
NL7309811A (fi)	1974-01-16
AU473000B2 (en)	1976-06-10
HU165158B (fi)	1974-06-28
DE2234651B2 (de)	1978-02-23
AT324322B (de)	1975-08-25
FR2192828A1 (fi)	1974-02-15
DE2234651C3 (de)	1978-11-09
SE380522B (sv)	1975-11-10
NL173748C (nl)	1984-03-01
IL42728A (en)	1976-05-31
FI56833C (fi)	1980-04-10
AU5801173A (en)	1975-01-16
PL91610B1 (fi)	1977-03-31
BE802358A (fr)	1974-01-14
IE38039L (en)	1974-01-14
RO64477A (fr)	1979-08-15
YU35353B (en)	1980-12-31
ZA734735B (en)	1974-06-26
NL173748B (nl)	1983-10-03
OA04546A (fr)	1980-04-30
ES416877A1 (es)	1976-02-16
DE2234651A1 (de)	1974-04-04
DK134400B (da)	1976-11-01
YU185873A (en)	1980-06-30
US3910952A (en)	1975-10-07
IL42728A0 (en)	1973-10-25
CA979893A (en)	1975-12-16
CH582141A5 (fi)	1976-11-30
GB1411350A (en)	1975-10-22
JPS4943970A (fi)	1974-04-25
SU474980A3 (ru)	1975-06-25
DK134400C (da)	1977-03-28
FR2192828B1 (fi)	1976-10-22
CS179418B2 (en)	1977-10-31

Publication	Publication Date	Title
SE407960B (sv)	1979-04-30	Anleggning for tillverkning av flerglasrutor
SE404019B (sv)	1978-09-18	Forfarande for framstellnig av n-fosfonometylglycin
SE409733B (sv)	1979-09-03	Net och forfarande for dess framstellning
NO142663C (no)	1980-09-24	Anordning for paafoering av limbaandlapper.
FI53940B (fi)	1978-05-31	Foerfarande och anordning foer framstaellning av en polymerskumstroem
NO144223C (no)	1981-07-15	Fremgangsmaate til fremstilling av strekkbart papir
FI56833B (fi)	1979-12-31	Foerfarande foer framstaellning av antiflogistiskt verkande (1-(p-klorbenzoyl)-5-metoxi-2-metyl-3-indol)-acetoxiaettiksyra och dess salter
NO143441C (no)	1981-02-11	Large scale integration (l.s.i.) skivepakke og fremgangsmaate for fremstilling av denne
SE7604260L (sv)	1976-04-12	Forfarande for isolering av ap-glykoproteiner
SE417968B (sv)	1981-04-27	Forfarande for framstellning av penamderivat
NO143220C (no)	1981-01-02	Fremgangsmaate for ekstraksjon av omegalaktamer
NO140478C (no)	1979-09-05	Fremgangsmaate for fremstilling av fibriller
NO138174C (no)	1978-07-26	Fremgangsmaate til fremstilling av antrakinon
SU439983A3 (ru)	1974-08-15	Способ получения производных этиленбензоила
CH532258A (de)	1972-12-31	Peilverfahren
SE414025B (sv)	1980-07-07	Forfarande for framstellning av fototropa flerfokala glasogonglas
BG20834A3 (bg)	1975-12-20	Устройство за регулиране тембъра на звука
FI55626B (fi)	1979-05-31	Anordning foer framstaellning av en behaollare
SE423540B (sv)	1982-05-10	Forfarande for framstellning av vissa 13-tiaprostaglandiner
SE7512972L (sv)	1975-11-18	Forfarande for framstellning av en mellanprodukt
NO139130C (no)	1979-01-10	Fremgangsmaate til fremstilling av 2-alkylamino-dihydropyridiner
FI56670B (fi)	1979-11-30	Foerfarande foer framstaellning av 5-cyklohexyl-6-halogenindan-1-karboxylsyraderivat
FI53452C (fi)	1978-05-10	Foerfarande foer framstaellning av n-laegre-alkyl-1,4-dihydro-4-oxokinolin-3-karboxylsyror
NO138364C (no)	1978-08-23	Anordning til fremstilling av fiberarmerte plastroer
FI55176B (fi)	1979-02-28	Foerfarande foer framstaellning av isopropylaminer