SE380522B - Forfarande for framstellning av (1- (p-klorbensoyl)-5-metoxi-2-metyl-3-indol) - acetoxiettiksyra med antiflogistisk verkan - Google Patents

Forfarande for framstellning av (1- (p-klorbensoyl)-5-metoxi-2-metyl-3-indol) - acetoxiettiksyra med antiflogistisk verkan

Info

Publication number: SE380522B
Authority: SE; Sweden
Prior art keywords: chlorenbenoyl; acetoxyetic; antiflogistic; indole; methoxy
Prior art date: 1972-07-14

Application number

SE7309900A

Other languages

English (en)

Inventor

K-H Boltze

O Brendler

H-D Dell

H Jacobi

Original Assignee

Troponwerke Dinklage & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-07-14

Filing date

1973-07-13

Publication date

1975-11-10

1973-07-13 Application filed by Troponwerke Dinklage & Co filed Critical Troponwerke Dinklage & Co

1975-11-10 Publication of SE380522B publication Critical patent/SE380522B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SE7309900A 1972-07-14 1973-07-13 Forfarande for framstellning av (1- (p-klorbensoyl)-5-metoxi-2-metyl-3-indol) - acetoxiettiksyra med antiflogistisk verkan SE380522B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2234651A DE2234651C3 (de)	1972-07-14	1972-07-14	Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen

Publications (1)

Publication Number	Publication Date
SE380522B true SE380522B (sv)	1975-11-10

Family

ID=5850654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7309900A SE380522B (sv)	1972-07-14	1973-07-13	Forfarande for framstellning av (1- (p-klorbensoyl)-5-metoxi-2-metyl-3-indol) - acetoxiettiksyra med antiflogistisk verkan

Country Status (27)

Country	Link
US (1)	US3910952A (sv)
JP (1)	JPS5147708B2 (sv)
AR (1)	AR197345A1 (sv)
AT (1)	AT324322B (sv)
AU (1)	AU473000B2 (sv)
BE (1)	BE802358A (sv)
CA (1)	CA979893A (sv)
CH (1)	CH582141A5 (sv)
CS (1)	CS179418B2 (sv)
DD (1)	DD107917A5 (sv)
DE (1)	DE2234651C3 (sv)
DK (1)	DK134400C (sv)
ES (1)	ES416877A1 (sv)
FI (1)	FI56833C (sv)
FR (1)	FR2192828B1 (sv)
GB (1)	GB1411350A (sv)
HU (1)	HU165158B (sv)
IE (1)	IE38039B1 (sv)
IL (1)	IL42728A (sv)
NL (1)	NL173748C (sv)
OA (1)	OA04546A (sv)
PL (1)	PL91610B1 (sv)
RO (1)	RO64477A (sv)
SE (1)	SE380522B (sv)
SU (1)	SU474980A3 (sv)
YU (1)	YU35353B (sv)
ZA (1)	ZA734735B (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1531546A (en) *	1976-05-19	1978-11-08	Pierrel Spa	Anti-inflammatory indole derivative
JPS52156862A (en) *	1976-06-22	1977-12-27	Hisamitsu Pharmaceut Co Inc	Novel indoleacetic acid ester derivatives
CS190723B1 (en) *	1976-06-30	1979-06-29	Ludmila Fisnerova	2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same
GB1587070A (en) *	1977-06-02	1981-03-25	Sterwin Ag	Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them
DE2735537A1 (de) *	1977-08-06	1979-02-22	Troponwerke Gmbh & Co Kg	Indolacetoxyacetylaminosaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2943125A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure
DE2943127A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	(1-(4-chlorbenzoyl)-methoxy-2-methyl-3-indol) -acetoxyessigsaeuremonohydrat, verfahren zur herstellung sowie dessen verwendung in arzneimitteln
DE2943126A1 (de) *	1979-10-25	1981-05-14	Troponwerke GmbH & Co KG, 5000 Köln	Laevulinoyloxyessigsaeure und verfahren zu ihrer herstellung
FR2499076A1 (fr) *	1981-02-02	1982-08-06	Panmedica Laboratoires	Nouveaux derives de l'acide ((indol-3 yl)-3 amino-2 propionyloxy)-2 acetique, procedes pour leur preparation et medicaments les contenant
CH653326A5 (de) *	1981-12-28	1985-12-31	Siegfried Ag	Verfahren zur herstellung eines indolderivates.
DE3206886A1 (de) *	1982-02-26	1983-10-27	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3- indolacetoxyessigsaeure
DE3206888A1 (de) *	1982-02-26	1983-09-15	Troponwerke GmbH & Co KG, 5000 Köln	Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure
JPS59204172A (ja) *	1983-04-28	1984-11-19	Kowa Co	アセメタシンの製造法
JPS60112760A (ja) *	1983-11-18	1985-06-19	Green Cross Corp:The	インド−ル酢酸誘導体及びその脂肪乳剤
WO2006099677A1 (en) *	2005-03-24	2006-09-28	Medical Therapies Limited	Metal complexes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3775429A (en) *	1966-10-13	1973-11-27	Merck & Co Inc	Process for preparing 3-indolyl acetic acids
US3518280A (en) *	1968-06-27	1970-06-30	Merck & Co Inc	1-p-chlorobenzoyl-2-methyl-5-methoxyindole-3-malonic acid derivatives

1972
- 1972-07-14 DE DE2234651A patent/DE2234651C3/de not_active Expired
1973
- 1973-06-28 US US374615A patent/US3910952A/en not_active Expired - Lifetime
- 1973-07-06 CS CS7300004899A patent/CS179418B2/cs unknown
- 1973-07-06 SU SU1942666A patent/SU474980A3/ru active
- 1973-07-09 YU YU1858/73A patent/YU35353B/xx unknown
- 1973-07-11 RO RO7375429A patent/RO64477A/ro unknown
- 1973-07-11 PL PL1973163991A patent/PL91610B1/pl unknown
- 1973-07-12 FI FI2213/73A patent/FI56833C/fi active
- 1973-07-12 CA CA176,315A patent/CA979893A/en not_active Expired
- 1973-07-12 DD DD172231A patent/DD107917A5/xx unknown
- 1973-07-12 IL IL42728A patent/IL42728A/en unknown
- 1973-07-12 HU HUTO961A patent/HU165158B/hu unknown
- 1973-07-12 AU AU58011/73A patent/AU473000B2/en not_active Expired
- 1973-07-12 IE IE1181/73A patent/IE38039B1/xx unknown
- 1973-07-12 ZA ZA734735A patent/ZA734735B/xx unknown
- 1973-07-13 BE BE133498A patent/BE802358A/xx not_active IP Right Cessation
- 1973-07-13 AR AR249094A patent/AR197345A1/es active
- 1973-07-13 GB GB3343573A patent/GB1411350A/en not_active Expired
- 1973-07-13 DK DK389973A patent/DK134400C/da not_active IP Right Cessation
- 1973-07-13 SE SE7309900A patent/SE380522B/sv unknown
- 1973-07-13 FR FR7325791A patent/FR2192828B1/fr not_active Expired
- 1973-07-13 AT AT619473A patent/AT324322B/de not_active IP Right Cessation
- 1973-07-13 CH CH1026673A patent/CH582141A5/xx not_active IP Right Cessation
- 1973-07-13 NL NLAANVRAGE7309811,A patent/NL173748C/xx not_active IP Right Cessation
- 1973-07-13 OA OA54967A patent/OA04546A/xx unknown
- 1973-07-13 ES ES416877A patent/ES416877A1/es not_active Expired
- 1973-07-13 JP JP48079201A patent/JPS5147708B2/ja not_active Expired

Also Published As

Publication number	Publication date
JPS5147708B2 (sv)	1976-12-16
DD107917A5 (sv)	1974-08-20
AR197345A1 (es)	1974-03-29
IE38039B1 (en)	1977-12-07
NL7309811A (sv)	1974-01-16
AU473000B2 (en)	1976-06-10
HU165158B (sv)	1974-06-28
DE2234651B2 (de)	1978-02-23
AT324322B (de)	1975-08-25
FR2192828A1 (sv)	1974-02-15
DE2234651C3 (de)	1978-11-09
NL173748C (nl)	1984-03-01
IL42728A (en)	1976-05-31
FI56833B (fi)	1979-12-31
FI56833C (fi)	1980-04-10
AU5801173A (en)	1975-01-16
PL91610B1 (sv)	1977-03-31
BE802358A (fr)	1974-01-14
IE38039L (en)	1974-01-14
RO64477A (fr)	1979-08-15
YU35353B (en)	1980-12-31
ZA734735B (en)	1974-06-26
NL173748B (nl)	1983-10-03
OA04546A (fr)	1980-04-30
ES416877A1 (es)	1976-02-16
DE2234651A1 (de)	1974-04-04
DK134400B (da)	1976-11-01
YU185873A (en)	1980-06-30
US3910952A (en)	1975-10-07
IL42728A0 (en)	1973-10-25
CA979893A (en)	1975-12-16
CH582141A5 (sv)	1976-11-30
GB1411350A (en)	1975-10-22
JPS4943970A (sv)	1974-04-25
SU474980A3 (ru)	1975-06-25
DK134400C (da)	1977-03-28
FR2192828B1 (sv)	1976-10-22
CS179418B2 (en)	1977-10-31

Publication	Publication Date	Title
SE385885B (sv)	1976-07-26	Foerfarande foer framstaellning av 4-amino-6-arylpyrimidinderivat
NO140731C (no)	1979-10-31	Fremgangsmaate for fremstilling av dimetyleter
SE380522B (sv)	1975-11-10	Forfarande for framstellning av (1- (p-klorbensoyl)-5-metoxi-2-metyl-3-indol) - acetoxiettiksyra med antiflogistisk verkan
NO138883C (no)	1978-11-29	Fremgangsmaate for fremstilling av oksiranforbindelser
SE397677B (sv)	1977-11-14	Forfarande for framstellning av en alfa-dipeptidlagalkylester av l-asparaginsyra
SE385698B (sv)	1976-07-19	Forfarande for framstellning av kinolinettiksyraderivat
SE382053B (sv)	1976-01-12	Forfarande for framstellning av bifenylylalkanoylaminopyridiner
SE396387B (sv)	1977-09-19	Forfarande for framstellning av 1-(2-karboxikromonyloxi)-2-hydroxi-3-p-cyanfenoxi-propaner med terapentisk verkan
SE405477B (sv)	1978-12-11	Forfarande for framstellning av tetrazolyl-kinaldinsyraderivat med farmakologisk verkan
SE399701B (sv)	1978-02-27	Forfarande for framstellning av hydroxyalkyldiamin
SE403911B (sv)	1978-09-11	Forfarande for framstellning av aroylsubstituerade fenylettiksyraderivat med anti-inflammatorisk verkan
SE383151B (sv)	1976-03-01	Forfarande for framstellning av 1-hydroxi-2-pyridoner
SE394436B (sv)	1977-06-27	Forfarande for framstellning av 7-halogen-linkomyciner
SE399708B (sv)	1978-02-27	Forfarande for framstellning av tioxanton-2-karboxylsyraderivat
SE7511680L (sv)	1975-10-17	Forfarande for framstellning av furanderivat
SE402451B (sv)	1978-07-03	Forfarande for framstellning av 14-desoxi-14-acetoximutilin
SE380273B (sv)	1975-11-03	Forfarande for framstellning av tiopyrimidinderivat
SE385011B (sv)	1976-05-31	Forfarande for framstellning av alfa-linkosaminider
SE384685B (sv)	1976-05-17	Forfarande for framstellning av linkomycinderivat
SE393111B (sv)	1977-05-02	Forfarande for framstellning av d-2-halogen-6-metyl-8-substituerad - ergolin
SE380272B (sv)	1975-11-03	Forfarande for framstellning av n-fosfonmetylglycin
SE408418B (sv)	1979-06-11	Forfarande for framstellning av 5-fluor-pyrimidiner
FI56830B (fi)	1979-12-31	Foerfarande foer framstaellning av asparaginylgrupper innehaollande biologiskt aktiva polypeptider
SE395699B (sv)	1977-08-22	Forfarande for framstellning av kinuklidin-kinolinderivat
SE393808B (sv)	1977-05-23	Forfarande for framstellning av isomaltit