IL155335A0 - Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament - Google Patents

Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Info

Publication number: IL155335A0
Authority: IL; Israel
Prior art keywords: medicament; producing; production; same; crystalline monohydrate
Prior art date: 2000-10-12

Application number

IL15533501A

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2001-09-28

Publication date

2003-11-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL155335(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-09-28 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2003-11-23 Publication of IL155335A0 publication Critical patent/IL155335A0/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL15533501A 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament IL155335A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10050621		2000-10-12
PCT/EP2001/011225 WO2002030928A1 (en)	2000-10-12	2001-09-28	Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Publications (1)

Publication Number	Publication Date
IL155335A0 true IL155335A0 (en)	2003-11-23

Family

ID=7659568

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15533501A IL155335A0 (en)	2000-10-12	2001-09-28	Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament
IL155335A IL155335A (en)	2000-10-12	2003-04-10	Crystalline monohydrate of tiotropium bromide, method for producing the same and the use thereof in the production of a medicament

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL155335A IL155335A (en)	2000-10-12	2003-04-10	Crystalline monohydrate of tiotropium bromide, method for producing the same and the use thereof in the production of a medicament

Country Status (47)

Country	Link
EP (2)	EP1468998A1 (en)
JP (1)	JP3764422B2 (en)
KR (1)	KR100823860B1 (en)
CN (2)	CN100519558C (en)
AP (1)	AP1572A (en)
AR (2)	AR034389A1 (en)
AT (1)	ATE276253T1 (en)
AU (2)	AU1499602A (en)
BG (1)	BG66161B1 (en)
BR (1)	BR0114584A (en)
CA (1)	CA2425539C (en)
CR (1)	CR6938A (en)
CZ (1)	CZ301841B6 (en)
DE (1)	DE50103666D1 (en)
DK (1)	DK1326862T3 (en)
DZ (1)	DZ3478A1 (en)
EA (1)	EA004381B1 (en)
EC (1)	ECSP034540A (en)
EE (1)	EE04567B1 (en)
EG (1)	EG24142A (en)
ES (1)	ES2228965T3 (en)
GE (1)	GEP20063905B (en)
HK (2)	HK1060567A1 (en)
HR (1)	HRP20030276B1 (en)
HU (1)	HU226830B1 (en)
IL (2)	IL155335A0 (en)
IS (1)	IS2339B (en)
MA (1)	MA25842A1 (en)
ME (2)	ME00243B (en)
MX (1)	MXPA03003221A (en)
MY (1)	MY126931A (en)
NO (1)	NO328465B1 (en)
NZ (1)	NZ525733A (en)
OA (1)	OA12403A (en)
PE (1)	PE20020422A1 (en)
PL (1)	PL207870B1 (en)
PT (1)	PT1326862E (en)
RS (1)	RS50218B (en)
SA (1)	SA01220412B1 (en)
SI (1)	SI1326862T1 (en)
SK (1)	SK287009B6 (en)
TR (1)	TR200402579T4 (en)
TW (1)	TW589313B (en)
UA (1)	UA74215C2 (en)
UY (2)	UY26962A1 (en)
WO (1)	WO2002030928A1 (en)
ZA (1)	ZA200302500B (en)

Families Citing this family (74)

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US6608055B2 (en)	2001-06-22	2003-08-19	Boehringer Ingelheim Pharma Kg	Crystalline anticholinergic, processes for preparing it and its use for preparing a pharmaceutical composition
KR100971616B1 (en) *	2001-06-22	2010-07-22	베링거 잉겔하임 파르마 게엠베하 운트 코 카게	Crystalline anticholinergic method for its production and pharmaceutical composition comprising the same
DE10212264A1 (en)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Crystalline micronisate, process for its preparation and its use for the manufacture of a medicament
US7311894B2 (en)	2002-03-28	2007-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations containing an anticholinergic
DE10214263A1 (en) *	2002-03-28	2003-10-16	Boehringer Ingelheim Pharma	HFA suspension formulations containing an anticholinergic
US7244415B2 (en)	2002-03-28	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations of an anhydrate
US7056916B2 (en)	2002-11-15	2006-06-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments for the treatment of chronic obstructive pulmonary disease
DE10317461A1 (en)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Preparing microparticles labeled with technetium, useful as powders for inhalation, e.g. to study deposition of pharmaceuticals, such as anticholinergic agents, involves incubation with solution of technetium salt
AU2004285683C1 (en) *	2003-11-03	2011-09-08	Boehringer Ingelheim International Gmbh	Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
EA012369B1 (en) *	2003-11-03	2009-10-30	Бёрингер Ингельхайм Интернациональ Гмбх	Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
US7968717B2 (en)	2003-11-03	2011-06-28	Boehringer Ingelhein International Gmbh	Crystalline anhydrate with anticholinergic efficacy
RS20060291A (en) *	2003-11-03	2008-06-05	Boehringer Ingelheim International Gmbh.,	Novel crystalline anhydride with anticholinergic effect
DE102004016179A1 (en) *	2004-03-30	2005-10-20	Boehringer Ingelheim Pharma	Compounds for the treatment of proliferative processes
PT1781298E (en)	2004-04-22	2012-02-03	Boehringer Ingelheim Int	Pharmaceutical combinations containing benzoxazine for treating respiratory diseases
DE102004024454A1 (en)	2004-05-14	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Novel enantiomerically pure beta agonists, process for their preparation and their use as pharmaceuticals
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
ATE427108T1 (en)	2004-08-11	2009-04-15	Boehringer Ingelheim Pharma	MEDICINAL PRODUCTS CONTAINING ANTICHOLINERGICS FOR THE TREATMENT OF DISEASES OF THE URINARY TRACT
US20060079544A1 (en) *	2004-08-13	2006-04-13	Boehringer Ingelheim International Gmbh	Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
DE102004048389A1 (en)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modification of surfaces of lactose as adjuvant for use with powder inhalants
EA013776B1 (en) *	2004-10-21	2010-06-30	Бёрингер Ингельхайм Интернациональ Гмбх	Blister for inhalers
CA2600636A1 (en) *	2005-03-09	2006-09-14	Boehringer Ingelheim International Gmbh	New pharmaceutical compositions based on anticholinergics and pde 5-inhibitors
AU2006237354B2 (en)	2005-04-21	2012-03-01	Boehringer Ingelheim International Gmbh	Dihydrothienopyrimidines for the treatment of inflammatory diseases
BRPI0609899A2 (en)	2005-04-28	2010-05-11	Boehringer Ingelheim International Gmbh	compounds for the treatment of inflammatory diseases, their use, pharmaceutical formulations, drug combinations and intermediate products
EP1879888A2 (en) *	2005-05-02	2008-01-23	Boehringer Ingelheim International GmbH	Crystalline forms of tiotropium bromide
PL1881980T3 (en)	2005-05-02	2013-01-31	Boehringer Ingelheim Int	Novel crystalline forms of tiotropium bromide
JP5315048B2 (en) *	2005-06-15	2013-10-16	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Method for producing novel tiotropium salt, novel tiotropium salt and pharmaceutical composition thereof
DE102005030733A1 (en)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug combinations for the treatment of respiratory diseases containing long-acting beta-2 agonists and at least one other active ingredient
RU2422144C2 (en) *	2005-08-06	2011-06-27	Бёрингер Ингельхайм Интернациональ Гмбх	Application of tiotropium salts for treatment of severe forms of persistent asthma
JP5270343B2 (en)	2005-08-15	2013-08-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Beta mimetic manufacturing method
TWI396541B (en)	2005-10-10	2013-05-21	Boehringer Ingelheim Int	Novel combinations of medicaments for the treatment of respiratory diseases
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
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WO2007075858A2 (en) *	2005-12-19	2007-07-05	Sicor Inc.	Novel forms of tiotropium bromide and processes for preparation thereof
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EP1847543A1 (en)	2006-04-19	2007-10-24	Boehringer Ingelheim Pharma GmbH & Co. KG	Dihydrothienopyrimidines for the treatment of inflammatory diseases
US20080051582A1 (en)	2006-07-10	2008-02-28	Sicor Inc.	Process for the preparation of tiotropium bromide
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ATE542825T1 (en)	2007-10-19	2012-02-15	Boehringer Ingelheim Int	SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES
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WO2011073155A1 (en)	2009-12-17	2011-06-23	Boehringer Ingelheim International Gmbh	Novel antagonists for ccr2 and uses thereof
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BR112012018865A2 (en)	2010-01-29	2016-04-12	Boehringer Ingelheim Int	substituted naphthyridines and their use as syk kinase inhibitors
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EP2569298B1 (en)	2010-05-12	2015-11-25	Boehringer Ingelheim International GmbH	Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments
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2001
- 2001-09-28 BR BR0114584-3A patent/BR0114584A/en active Pending
- 2001-09-28 CN CNB2005100977370A patent/CN100519558C/en not_active Ceased
- 2001-09-28 DZ DZ013478A patent/DZ3478A1/en active
- 2001-09-28 JP JP2002534314A patent/JP3764422B2/en not_active Expired - Lifetime
- 2001-09-28 EA EA200300457A patent/EA004381B1/en not_active IP Right Cessation
- 2001-09-28 ME MEP-2008-400A patent/ME00243B/en unknown
- 2001-09-28 AT AT01983510T patent/ATE276253T1/en active
- 2001-09-28 ME MEP-400/08A patent/MEP40008A/en unknown
- 2001-09-28 HU HU0301022A patent/HU226830B1/en unknown
- 2001-09-28 SI SI200130219T patent/SI1326862T1/en unknown
- 2001-09-28 DE DE50103666T patent/DE50103666D1/en not_active Expired - Lifetime
- 2001-09-28 ES ES01983510T patent/ES2228965T3/en not_active Expired - Lifetime
- 2001-09-28 OA OA1200300107A patent/OA12403A/en unknown
- 2001-09-28 EP EP04016877A patent/EP1468998A1/en not_active Withdrawn
- 2001-09-28 CA CA002425539A patent/CA2425539C/en not_active Expired - Lifetime
- 2001-09-28 EE EEP200300171A patent/EE04567B1/en unknown
- 2001-09-28 SK SK436-2003A patent/SK287009B6/en not_active IP Right Cessation
- 2001-09-28 UA UA2003054185A patent/UA74215C2/en unknown
- 2001-09-28 CZ CZ20031025A patent/CZ301841B6/en not_active IP Right Cessation
- 2001-09-28 IL IL15533501A patent/IL155335A0/en active IP Right Grant
- 2001-09-28 NZ NZ525733A patent/NZ525733A/en not_active IP Right Cessation
- 2001-09-28 PL PL366041A patent/PL207870B1/en unknown
- 2001-09-28 PT PT01983510T patent/PT1326862E/en unknown
- 2001-09-28 AU AU1499602A patent/AU1499602A/en active Pending
- 2001-09-28 RS YU27303A patent/RS50218B/en unknown
- 2001-09-28 CN CNB018171435A patent/CN1221549C/en not_active Ceased
- 2001-09-28 KR KR1020037005083A patent/KR100823860B1/en active IP Right Grant
- 2001-09-28 GE GE5214A patent/GEP20063905B/en unknown
- 2001-09-28 DK DK01983510T patent/DK1326862T3/en active
- 2001-09-28 AP APAP/P/2003/002775A patent/AP1572A/en active Active
- 2001-09-28 EP EP01983510A patent/EP1326862B1/en not_active Expired - Lifetime
- 2001-09-28 WO PCT/EP2001/011225 patent/WO2002030928A1/en active IP Right Grant
- 2001-09-28 AU AU2002214996A patent/AU2002214996B2/en not_active Expired
- 2001-09-28 TR TR2004/02579T patent/TR200402579T4/en unknown
- 2001-09-28 MX MXPA03003221A patent/MXPA03003221A/en active IP Right Grant
- 2001-10-02 SA SA01220412A patent/SA01220412B1/en unknown
- 2001-10-09 TW TW090124963A patent/TW589313B/en active
- 2001-10-09 EG EG20011058A patent/EG24142A/en active
- 2001-10-10 UY UY26962A patent/UY26962A1/en not_active Application Discontinuation
- 2001-10-10 PE PE2001001000A patent/PE20020422A1/en active IP Right Grant
- 2001-10-10 MY MYPI20014705A patent/MY126931A/en unknown
- 2001-10-12 AR ARP010104782A patent/AR034389A1/en active Pending
2003
- 2003-03-26 CR CR6938A patent/CR6938A/en unknown
- 2003-03-28 BG BG107687A patent/BG66161B1/en active Active
- 2003-03-31 ZA ZA200302500A patent/ZA200302500B/en unknown
- 2003-04-07 EC EC2003004540A patent/ECSP034540A/en unknown
- 2003-04-08 MA MA27102A patent/MA25842A1/en unknown
- 2003-04-09 IS IS6772A patent/IS2339B/en unknown
- 2003-04-10 HR HR20030276A patent/HRP20030276B1/en not_active IP Right Cessation
- 2003-04-10 IL IL155335A patent/IL155335A/en unknown
- 2003-04-11 NO NO20031694A patent/NO328465B1/en not_active IP Right Cessation
2004
- 2004-05-20 HK HK04103583A patent/HK1060567A1/en not_active IP Right Cessation
2006
- 2006-06-07 HK HK06106478.2A patent/HK1086557A1/en not_active IP Right Cessation
2008
- 2008-09-19 AR ARP080104109A patent/AR068527A2/en unknown
2013
- 2013-07-11 UY UY34901A patent/UY34901A/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
EA004381B1 (en)	2004-04-29
PL207870B1 (en)	2011-02-28
EG24142A (en)	2008-08-06
AR068527A2 (en)	2009-11-18
IS2339B (en)	2008-02-15
AR034389A1 (en)	2004-02-25
UY34901A (en)	2015-02-27
AP2003002775A0 (en)	2003-03-31
PE20020422A1 (en)	2002-06-28
CA2425539C (en)	2007-04-03
JP3764422B2 (en)	2006-04-05
ME00243B (en)	2011-05-10
EP1326862B1 (en)	2004-09-15
SK4362003A3 (en)	2003-08-05
DK1326862T3 (en)	2004-11-22
AP1572A (en)	2006-02-13
EP1468998A1 (en)	2004-10-20
ZA200302500B (en)	2004-04-22
HU226830B1 (en)	2009-11-30
TW589313B (en)	2004-06-01
BR0114584A (en)	2003-08-26
KR20030042008A (en)	2003-05-27
OA12403A (en)	2006-04-18
HK1060567A1 (en)	2004-08-13
DE50103666D1 (en)	2004-10-21
SI1326862T1 (en)	2005-02-28
HUP0301022A2 (en)	2003-10-28
BG107687A (en)	2003-09-30
JP2004526668A (en)	2004-09-02
HUP0301022A3 (en)	2005-12-28
MA25842A1 (en)	2003-07-01
IL155335A (en)	2009-02-11
EA200300457A1 (en)	2003-10-30
WO2002030928A1 (en)	2002-04-18
HK1086557A1 (en)	2006-09-22
TR200402579T4 (en)	2004-12-21
NO328465B1 (en)	2010-02-22
HRP20030276A2 (en)	2005-02-28
IS6772A (en)	2003-04-09
SK287009B6 (en)	2009-09-07
GEP20063905B (en)	2006-08-25
EP1326862A1 (en)	2003-07-16
MEP40008A (en)	2011-02-10
CR6938A (en)	2004-10-28
NZ525733A (en)	2005-01-28
BG66161B1 (en)	2011-09-30
YU27303A (en)	2006-05-25
SA01220412B1 (en)	2006-11-05
DZ3478A1 (en)	2002-04-18
RS50218B (en)	2009-07-15
PT1326862E (en)	2004-11-30
NO20031694L (en)	2003-04-11
ES2228965T3 (en)	2005-04-16
UA74215C2 (en)	2005-11-15
ECSP034540A (en)	2003-07-25
AU1499602A (en)	2002-04-22
UY26962A1 (en)	2002-06-20
CN100519558C (en)	2009-07-29
CA2425539A1 (en)	2003-04-11
PL366041A1 (en)	2005-01-24
CN1733761A (en)	2006-02-15
CN1221549C (en)	2005-10-05
EE200300171A (en)	2003-06-16
AU2002214996B2 (en)	2007-03-15
KR100823860B1 (en)	2008-04-21
CZ301841B6 (en)	2010-07-07
EE04567B1 (en)	2005-12-15
MXPA03003221A (en)	2004-12-03
MY126931A (en)	2006-10-31
ATE276253T1 (en)	2004-10-15
HRP20030276B1 (en)	2006-02-28
CN1469877A (en)	2004-01-21
NO20031694D0 (en)	2003-04-11

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Legal Events

Date	Code	Title	Description
2009-12-24	FF	Patent granted
2009-12-24	KB	Patent renewed